Andrea C. Vaiana

Staff Status
campusgoe
 

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  • 2019 Journal Article | 
    ​ ​Igaev, Maxim, Carsten Kutzner, Lars V. Bock, Andrea C. Vaiana, and Helmut Grubmüller. "Automated cryo-EM structure refinement using correlation-driven molecular dynamics​." ​eLife ​8 (2019): . ​https://doi.org/10.7554/eLife.43542.
    Details  DOI 
  • 2017 Journal Article
    ​ ​Huter, Paul, Stefan Arenz, Lars V. Bock, Michael Graf, Jan Ole Frister, Andre Heuer, Lauri Peil et al. "Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P​." ​Molecular cell ​68, no. 3 (2017): ​515.e6​-527.e6​. ​https://doi.org/10.1016/j.molcel.2017.10.014.
    Details  DOI  PMID  PMC 
  • 2016 Journal Article | 
    ​ ​Arenz, Stefan, Lars V. Bock, Michael Graf, C. Axel Innis, Roland Beckmann, Helmut Grubmüller, Andrea C. Vaiana, and Daniel N. Wilson. "A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest​." ​Nature communications ​7 (2016): ​12026​. ​https://doi.org/10.1038/ncomms12026.
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​Bock, Lars V., Stefan Arenz, Daniel N. Wilson, Helmut Grubmüller, and Andrea C. Vaiana. "ErmBL Translation on the Ribosome in the Presence of Erythromycin is Stalled by Inhibition of Peptide Bond Formation​." ​Biophysical Journal ​110, no. 3 (2016): ​234a​. ​https://doi.org/10.1016/j.bpj.2015.11.1291.
    Details  DOI 
  • 2016 Journal Article
    ​ ​Bock, Lars V., Christian Blau, Andrea C. Vaiana, and Helmut Grubmüller. "Low Energy Barriers and a Dynamic Contact Network between Ribosomal Subunits Enable Rapid tRNA Translocation​." ​Biophysical Journal ​110, no. 3 (2016): ​3a​. ​https://doi.org/10.1016/j.bpj.2015.11.061.
    Details  DOI 
  • 2015 Journal Article
    ​ ​Bock, Lars V., Christian Blau, Andrea C. Vaiana, and Helmut Grubmüller. "Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation​." ​Nucleic Acids Research ​43, no. 14 (2015): ​6747​-6760​. ​https://doi.org/10.1093/nar/gkv649.
    Details  DOI  PMID  PMC 
  • 2015 Journal Article
    ​ ​Blau, Christian, Lars Bock, Carsten Kutzner, Andrea Vaiana, and Helmut Grubmüller. "Bayesian cryo-EM Refinement​." ​Biophysical Journal ​108, no. 2 (2015): ​470a​. ​https://doi.org/10.1016/j.bpj.2014.11.2571.
    Details  DOI 
  • 2015 Journal Article
    ​ ​Vaiana, Andrea C., Carsten Kutzner, Lars V. Bock, Christian Blau, and Helmut Grubmüller. "Structural Determinants of Hybrid State Intermediates of the Bacterial Ribosome​." ​Biophysical Journal ​108, no. 2 (2015): ​318a​. ​https://doi.org/10.1016/j.bpj.2014.11.1730.
    Details  DOI 
  • 2015 Journal Article
    ​ ​Bock, Lars V., Christian Blau, Andrea C. Vaiana, and Helmut Grubmüller. "Balanced Interactions between Ribosomal Subunits Allow Rapid Large-Scale Rotation​." ​Biophysical Journal ​108, no. 2 (2015): ​26a​. ​https://doi.org/10.1016/j.bpj.2014.11.168.
    Details  DOI 
  • 2014 Journal Article
    ​ ​Vaiana, Andrea C., Carsten Kutzner, Lars V. Bock, Christian Blau, and Helmut Grubmüller. "Refining Crystal Structures Against Cryo-EM Data using Molecular Dynamics Simulations to Obtain a Complete Atomistic Pathway of Transfer RNA Translocation​." ​Biophysical Journal ​106, no. 2 (2014): ​240a​. ​https://doi.org/10.1016/j.bpj.2013.11.1405.
    Details  DOI 
  • 2014 Journal Article
    ​ ​Bock, Lars V., Christian Blau, Andrea C. Vaiana, and Helmut Grubmüller. "Concerted Interactions between Ribosomal Subunits Allow for Large-Scale Rotations​." ​Biophysical Journal ​106, no. 2 (2014): ​491a​. ​https://doi.org/10.1016/j.bpj.2013.11.2748.
    Details  DOI 
  • 2014 Conference Abstract
    ​ ​Blau, Christian, Lars V. Bock, Gunnar F. Schröder, Iakov I. Davydov, Niels Fischer, Holger Stark, Marina V. Rodnina, Andrea C. Vaiana, and Helmut Grubmüller. "Ribosomal Kinetics and Concerted Motions from Nanoseconds to Seconds​." ​In Biophysical Journal , Volume 106 , Issue 2 , 250a, ​1266-Plat. ​Cambridge: ​Cell Press, ​2014. https://doi.org/10.1016/j.bpj.2013.11.1463.
    Details  DOI  WoS 
  • 2014 Conference Abstract
    ​ ​Bock, Lars V., Christian Blau, Gunnar F. Schröder, Iakov I. Davydov, Niels Fischer, Holger Stark, Marina V. Rodnina, Andrea C. Vaiana, and Helmut Grubmüller. "Rapid and Stable Transfer RNA Translocation through the Ribosome Ensured by Specific Contact Mechanisms​." ​In Biophysical Journal, 106(Supplement 1), 493a-493a., ​Cambridge: ​Cell Press, ​2014. https://doi.org/10.1016/j.bpj.2013.11.2758.
    Details  DOI  WoS 
  • 2013 Journal Article
    ​ ​Blau, Christian, Lars V. Bock, Gunnar F. Schröder, Niels Fischer, Holger Stark, Marina V. Rodnina, Andrea C. Vaiana, and Helmut Grubmüller. "Rate Estimates from Sampling Sparse Transitions: TRNA Motion Limits Transitions between Ribosomal Translocation Intermediates​." ​Biophysical Journal ​104, no. 2 (2013): ​663a​. ​https://doi.org/10.1016/j.bpj.2012.11.3662.
    Details  DOI 
  • 2013 Journal Article
    ​ ​Bock, Lars V., Christian Blau, Gunnar F. Schröder, Niels Fischer, Holger Stark, Marina V. Rodnina, Andrea C. Vaiana, and Helmut Grubmüller. "Mechanisms for Efficient TRNA Translocation through the Ribosome​." ​Biophysical Journal ​104, no. 2 (2013): ​16a​. ​https://doi.org/10.1016/j.bpj.2012.11.118.
    Details  DOI 
  • 2013 Journal Article | Research Paper
    ​ ​Bock, Lars V., Christian Blau, Gunnar F. Schroeder, Iakov I. Davydov, Niels Fischer, Holger Stark, Marina V. Rodnina, Andrea C. Vaiana, and Helmut Grubmüller. "Energy barriers and driving forces in tRNA translocation through the ribosome​." ​Nature Structural & Molecular Biology ​20, no. 12 (2013): ​1390​-1396​. ​https://doi.org/10.1038/nsmb.2690.
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article
    ​ ​Blau, Christian, Lars V. Bock, Gunnar F. Schroeder, Niels Fischer, Holger Stark, Andrea C. Vaiana, and Helmut Grubmüller. "Contacts Between Ribosome Parts Refined by Molecular Dynamics Simulations​." ​Biophysical Journal ​102, no. 3 (2012): ​69a​. ​https://doi.org/10.1016/j.bpj.2011.11.405.
    Details  DOI 

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