Andrea C. Vaiana

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  • 2019 | Journal Article | 
    ​ ​Igaev M, Kutzner C, Bock LV, Vaiana AC, Grubmüller H. ​Automated cryo-EM structure refinement using correlation-driven molecular dynamics​. ​​eLife. ​2019;​8​. ​doi:10.7554/eLife.43542. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Huter P, Arenz S, Bock LV, Graf M, Frister JO, Heuer A, et al. ​Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P​. ​​Molecular cell. ​2017;​68​(3):​​515.e6​-527.e6​. ​doi:10.1016/j.molcel.2017.10.014. 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | 
    ​ ​Arenz S, Bock LV, Graf M, Innis CA, Beckmann R, Grubmüller H, et al. ​A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest​. ​​Nature communications. ​2016;​7​. ​doi:10.1038/ncomms12026. 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Bock LV, Arenz S, Wilson DN, Grubmüller H, Vaiana AC. ​ErmBL Translation on the Ribosome in the Presence of Erythromycin is Stalled by Inhibition of Peptide Bond Formation​. ​​Biophysical Journal. ​2016;​110​(3):​​234a​. ​doi:10.1016/j.bpj.2015.11.1291. 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Bock LV, Blau C, Vaiana AC, Grubmüller H. ​Low Energy Barriers and a Dynamic Contact Network between Ribosomal Subunits Enable Rapid tRNA Translocation​. ​​Biophysical Journal. ​2016;​110​(3):​​3a​. ​doi:10.1016/j.bpj.2015.11.061. 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Bock LV, Blau C, Vaiana AC, Grubmüller H. ​Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation​. ​​Nucleic Acids Research. ​2015;​43​(14):​​6747​-6760​. ​doi:10.1093/nar/gkv649. 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article
    ​ ​Blau C, Bock L, Kutzner C, Vaiana A, Grubmüller H. ​Bayesian cryo-EM Refinement​. ​​Biophysical Journal. ​2015;​108​(2):​​470a​. ​doi:10.1016/j.bpj.2014.11.2571. 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Vaiana AC, Kutzner C, Bock LV, Blau C, Grubmüller H. ​Structural Determinants of Hybrid State Intermediates of the Bacterial Ribosome​. ​​Biophysical Journal. ​2015;​108​(2):​​318a​. ​doi:10.1016/j.bpj.2014.11.1730. 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Bock LV, Blau C, Vaiana AC, Grubmüller H. ​Balanced Interactions between Ribosomal Subunits Allow Rapid Large-Scale Rotation​. ​​Biophysical Journal. ​2015;​108​(2):​​26a​. ​doi:10.1016/j.bpj.2014.11.168. 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​Vaiana AC, Kutzner C, Bock LV, Blau C, Grubmüller H. ​Refining Crystal Structures Against Cryo-EM Data using Molecular Dynamics Simulations to Obtain a Complete Atomistic Pathway of Transfer RNA Translocation​. ​​Biophysical Journal. ​2014;​106​(2):​​240a​. ​doi:10.1016/j.bpj.2013.11.1405. 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​Bock LV, Blau C, Vaiana AC, Grubmüller H. ​Concerted Interactions between Ribosomal Subunits Allow for Large-Scale Rotations​. ​​Biophysical Journal. ​2014;​106​(2):​​491a​. ​doi:10.1016/j.bpj.2013.11.2748. 
    ​Details  DOI 
  • 2014 | Conference Abstract
    ​ ​Blau C, Bock LV, Schröder GF, Davydov II, Fischer N, Stark H, et al. ​Ribosomal Kinetics and Concerted Motions from Nanoseconds to Seconds​. ​​Biophysical Journal , Volume 106 , Issue 2 , 250a. 58th Annual Meeting of the Biophysical-Society; ​2014-02-15​ - 2014-02-19​; ​​San Francisco, CA. ​Cambridge: ​Cell Press; ​2014.  p. 1266-Plat​. ​doi:10.1016/j.bpj.2013.11.1463.
    ​Details  DOI  WoS 
  • 2014 | Conference Abstract
    ​ ​Bock LV, Blau C, Schröder GF, Davydov II, Fischer N, Stark H, et al. ​Rapid and Stable Transfer RNA Translocation through the Ribosome Ensured by Specific Contact Mechanisms​. ​​Biophysical Journal, 106(Supplement 1), 493a-493a.. 58th Annual Meeting of the Biophysical-Society; ​2014-02-15​ - 2014-02-19​; ​​San Francisco, CA. ​Cambridge: ​Cell Press; ​2014. doi:10.1016/j.bpj.2013.11.2758.
    ​Details  DOI  WoS 
  • 2013 | Journal Article
    ​ ​Blau C, Bock LV, Schröder GF, Fischer N, Stark H, Rodnina MV, et al. ​Rate Estimates from Sampling Sparse Transitions: TRNA Motion Limits Transitions between Ribosomal Translocation Intermediates​. ​​Biophysical Journal. ​2013;​104​(2):​​663a​. ​doi:10.1016/j.bpj.2012.11.3662. 
    ​Details  DOI 
  • 2013 | Journal Article
    ​ ​Bock LV, Blau C, Schröder GF, Fischer N, Stark H, Rodnina MV, et al. ​Mechanisms for Efficient TRNA Translocation through the Ribosome​. ​​Biophysical Journal. ​2013;​104​(2):​​16a​. ​doi:10.1016/j.bpj.2012.11.118. 
    ​Details  DOI 
  • 2013 | Journal Article | Research Paper
    ​ ​Bock LV, Blau C, Schroeder GF, Davydov II, Fischer N, Stark H, et al. ​Energy barriers and driving forces in tRNA translocation through the ribosome​. ​​Nature Structural & Molecular Biology. ​2013;​20​(12):​​1390​-1396​. ​doi:10.1038/nsmb.2690. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Blau C, Bock LV, Schroeder GF, Fischer N, Stark H, Vaiana AC, et al. ​Contacts Between Ribosome Parts Refined by Molecular Dynamics Simulations​. ​​Biophysical Journal. ​2012;​102​(3):​​69a​. ​doi:10.1016/j.bpj.2011.11.405. 
    ​Details  DOI 

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