Dr. Jan Huisken

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  • 2024 | Lecture | 
    ​ ​Huisken J. ​Ein Flamingo geht auf Reisen: Mit dem Lichtblattmikroskop biologische Entwicklungsprozesse entschlüsseln​. ​Lecture presented at: Herz und Hirn - Gemeinsam im Fokus; ​2024-02-06; ​Göttingen. 
    ​Details 
  • 2021 | Preprint
    ​ ​Airs PM, Vaccaro K, Gallo KJ, Dinguirard N, Heimark ZW, Wheeler NJ, et al. ​Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi​. ​​2021. Available from: https://doi.org/10.1101/2021.08.24.456436​
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper
    ​ ​Weiss KR, Voigt FF, Shepherd DP, Huisken J. ​Tutorial: practical considerations for tissue clearing and imaging​. ​​Nature Protocols. ​2021;​16​(6):​​2732​-2748​. ​doi:10.1038/s41596-021-00502-8. 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Favreau PF, He J, Gil DA, Deming DA, Huisken J, Skala MC. ​Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy​. ​​Biomedical Optics Express. ​2020;​11​(5):​​2591​-2606​. ​doi:10.1364/BOE.389164. 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​He J, Huisken J. ​Image quality guided smart rotation improves coverage in microscopy​. ​​Nature Communications. ​2020;​11​(1):​​150​. ​doi:10.1038/s41467-019-13821-y. 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Asokan N, Daetwyler S, Bernas SN, Schmied C, Vogler S, Lambert K, et al. ​Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts​. ​​Scientific Reports. ​2020;​10​(1):​​13254​. ​doi:10.1038/s41598-020-69956-2. 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Daetwyler S, Günther U, Modes CD, Harrington K, Huisken J. ​Multi-sample SPIM image acquisition, processing and analysis of vascular growth in zebrafish​. ​​Development (Cambridge). ​2019;​146​(6). ​doi:10.1242/dev.173757. 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Chrispijn ND, Elurbe DM, Mickoleit M, Aben M, de Bakker DEM, Andralojc KM, et al. ​Loss of the Polycomb group protein Rnf2 results in derepression of tbx-transcription factors and defects in embryonic and cardiac development​. ​​Scientific Reports. ​2019;​9​(1):​​4327​. ​doi:10.1038/s41598-019-40867-1. 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Shah G, Thierbach K, Schmid B, Waschke J, Reade A, Hlawitschka M, et al. ​Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish​. ​​Nature Communications. ​2019;​10​(1):​​5753​. ​doi:10.1038/s41467-019-13625-0. 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Schmid B, Tripal P, Fraaß T, Kersten C, Ruder B, Grüneboom A, et al. ​3Dscript: animating 3D/4D microscopy data using a natural-language-based syntax​. ​​Nature Methods. ​2019;​16​(4):​​278​-280​. ​doi:10.1038/s41592-019-0359-1. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Preprint
    ​ ​Fadul J, Slattum GM, Redd NM, Jin MF, Redd MJ, Daetwyler S, et al. ​Basal extrusion drives cell invasion and mechanical stripping of E-cadherin​. ​​2018. Available from: https://doi.org/10.1101/463646​
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, et al. ​Continuous addition of progenitors forms the cardiac ventricle in zebrafish​. ​​Nature Communications. ​2018;​9​(1):​​2001​. ​doi:10.1038/s41467-018-04402-6. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Berndt F, Shah G, Power RM, Brugués J, Huisken J. ​Dynamic and non-contact 3D sample rotation for microscopy​. ​​Nature Communications. ​2018;​9​(1):​​5025​. ​doi:10.1038/s41467-018-07504-3. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Power RM, Huisken J. ​Adaptable, illumination patterning light sheet microscopy​. ​​Scientific Reports. ​2018;​8​(1):​​9615​. ​doi:10.1038/s41598-018-28036-2. 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper
    ​ ​Power RM, Huisken J. ​A guide to light-sheet fluorescence microscopy for multiscale imaging​. ​​Nature Methods. ​2017;​14​(4):​​360​-373​. ​doi:10.1038/nmeth.4224. 
    ​Details  DOI  PMID  PMC 
  • 2017 | Preprint
    ​ ​Asokan N, Daetwyler S, Bernas SN, Schmied C, Vogler S, Lambert K, et al. ​Continuous high-resolution in vivo imaging reveals tumor-specific dissemination in an embryonic zebrafish xenograft model​. ​​2017. Available from: https://doi.org/10.1101/215921​
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper | 
    ​ ​Weber M, Scherf N, Meyer AM, Panáková D, Kohl P, Huisken J. ​Cell-accurate optical mapping across the entire developing heart​. ​​eLife. ​2017;​6​. ​doi:10.7554/eLife.28307. 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Jahr W, Schmid B, Schmied C, Fahrbach FO, Huisken J. ​Hyperspectral light sheet microscopy​. ​​Nature Communications. ​2015;​6​(1):​​7990​. ​doi:10.1038/ncomms8990. 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Scherf N, Huisken J. ​The smart and gentle microscope​. ​​Nature Biotechnology. ​2015;​33​(8):​​815​-818​. ​doi:10.1038/nbt.3310. 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper
    ​ ​Reynaud EG, Peychl J, Huisken J, Tomancak P. ​Guide to light-sheet microscopy for adventurous biologists​. ​​Nature Methods. ​2015;​12​(1):​​30​-34​. ​doi:10.1038/nmeth.3222. 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | Research Paper
    ​ ​Mickoleit M, Schmid B, Weber M, Fahrbach FO, Hombach S, Reischauer S, et al. ​High-resolution reconstruction of the beating zebrafish heart​. ​​Nature Methods. ​2014;​11​(9):​​919​-922​. ​doi:10.1038/nmeth.3037. 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | Research Paper
    ​ ​Opitz R, Maquet E, Huisken J, Antonica F, Trubiroha A, Pottier G, et al. ​Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development​. ​​Developmental Biology. ​2012;​372​(2):​​203​-216​. ​doi:10.1016/j.ydbio.2012.09.011. 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | Research Paper
    ​ ​Mellman K, Huisken J, Dinsmore C, Hoppe C, Stainier DY. ​Fibrillin-2b regulates endocardial morphogenesis in zebrafish​. ​​Developmental Biology. ​2012;​372​(1):​​111​-119​. ​doi:10.1016/j.ydbio.2012.07.015. 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | Research Paper
    ​ ​Weber M, Huisken J. ​Omnidirectional microscopy​. ​​Nature Methods. ​2012;​9​(7):​​656​-657​. ​doi:10.1038/nmeth.2022. 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | Research Paper
    ​ ​Huisken J. ​Slicing embryos gently with laser light sheets​. ​​BioEssays. ​2012;​34​(5):​​406​-411​. ​doi:10.1002/bies.201100120. 
    ​Details  DOI  PMID  PMC 
  • 2011 | Journal Article | Research Paper
    ​ ​Weber M, Huisken J. ​Light sheet microscopy for real-time developmental biology​. ​​Current Opinion in Genetics & Development. ​2011;​21​(5):​​566​-572​. ​doi:10.1016/j.gde.2011.09.009. 
    ​Details  DOI  PMID  PMC 
  • 2010 | Journal Article | Research Paper
    ​ ​Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, et al. ​Cse1l is a negative regulator of CFTR-dependent fluid secretion​. ​​Current Biology. ​2010;​20​(20):​​1840​-1845​. ​doi:10.1016/j.cub.2010.09.012. 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article | Research Paper
    ​ ​Munson C, Huisken J, Bit-Avragim N, Kuo T, Dong PD, Ober EA, et al. ​Regulation of neurocoel morphogenesis by Pard6 gamma b​. ​​Developmental Biology. ​2008;​324​(1):​​41​-54​. ​doi:10.1016/j.ydbio.2008.08.033. 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article | Research Paper
    ​ ​Shin CH, Chung, Won-Suk, Hong, Sung-Kook, Ober EA, Verkade H, Field HA, et al. ​Multiple roles for Med12 in vertebrate endoderm development​. ​​Developmental Biology. ​2008;​317​(2):​​467​-479​. ​doi:10.1016/j.ydbio.2008.02.031. 
    ​Details  DOI  PMID  PMC 
  • 2007 | Journal Article | Research Paper
    ​ ​Swoger J, Verveer P, Greger K, Huisken J, Stelzer EHK. ​Multi-view image fusion improves resolution in three-dimensional microscopy​. ​​Optics Express. ​2007;​15​(13):​​8029​. ​doi:10.1364/OE.15.008029. 
    ​Details  DOI 
  • 2007 | Journal Article | Research Paper
    ​ ​Stainier D, Chi N, Shaw R, Huisken J, Jungblut B, Jan L. ​Cellular and genetic dissection of the cardiac electric system​. ​​Developmental Biology. ​2007;​306​(1):​​290​. ​doi:10.1016/j.ydbio.2007.03.055. 
    ​Details  DOI 
  • 2007 | Journal Article | Research Paper
    ​ ​Huisken J, Stainier DYR. ​Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM)​. ​​Optics Letters. ​2007;​32​(17):​​2608​. ​doi:10.1364/OL.32.002608. 
    ​Details  DOI 
  • 2006 | Book Chapter
    ​ ​Huisken J, Swoger J, Lindek S, Stelzer EHK. ​Selective Plane Illumination Microscopy​. ​In: Pawley JB​, editor. ​Handbook Of Biological Confocal Microscopy. ​Springer; ​2006. p. 672​-679​. ​doi:10.1007/978-0-387-45524-2_37. 
    ​Details  DOI 
  • 2003 | Journal Article | Research Paper
    ​ ​Swoger J, Huisken J, Stelzer EHK. ​Multiple imaging axis microscopy improves resolution for thick-sample applications​. ​​Optics Letters. ​2003;​28​(18):​​1654​. ​doi:10.1364/OL.28.001654. 
    ​Details  DOI 
  • 2002 | Journal Article | Research Paper
    ​ ​Huisken J, Stelzer EHK. ​Optical levitation of absorbing particles with a nominally Gaussian laser beam​. ​​Optics Letters. ​2002;​27​(14):​​1223​. ​doi:10.1364/OL.27.001223. 
    ​Details  DOI 

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