Prof. Dr. Uwe Michel

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unigoe
 

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Small and long RNA transcriptome of whole human cerebrospinal fluid and serum as compared to their extracellular vesicle fractions reveal profound differences in expression patterns and impacts on biological processes​
    Michel, U. ; Shomroni, O. ; Müller, B.; Lange, P. ; Salinas, G. ; Bähr, M.   & Koch, J.-C. ​ (2022) 
    Journal of Translational Medicine, 20(1) art. 413​.​ DOI: https://doi.org/10.1186/s12967-022-03612-3 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Cytoskeletal assembly in axonal outgrowth and regeneration analyzed on the nanoscale​
    Hofmann, M.; Biller, L.; Michel, U. ; Bähr, M.   & Koch, J.-C. ​ (2022) 
    Scientific Reports, 12(1).​ DOI: https://doi.org/10.1038/s41598-022-18562-5 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo​
    Ribas, V. T. ; Vahsen, B. F.; Tatenhorst, L. ; Estrada, V.; Dambeck, V. ; Almeida, R. A. & Bähr, M.  et al.​ (2021) 
    Cell Death & Disease, 12(2).​ DOI: https://doi.org/10.1038/s41419-021-03503-3 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing​
    Vahsen, B. F.; Ribas, V. T. ; Sundermeyer, J.; Boecker, A.; Dambeck, V. ; Lenz, C.   & Shomroni, O.  et al.​ (2020) 
    Cell Death and Differentiation, 27(10) pp. 2810​-2827​.​ DOI: https://doi.org/10.1038/s41418-020-0543-y 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis​
    Llorens, F. ; Thüne, K. ; Martí, E.; Kanata, E.; Dafou, D.; Díaz-Lucena, D. & Vivancos, A. et al.​ (2018) 
    PLOS Pathogens, 14(1) art. e1006802​.​ DOI: https://doi.org/10.1371/journal.ppat.1006802 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease​
    Llorens, F. ; Fischer, A. ; Thüne, K. ; Sikorska, B.; Schmitz, M.; Tahir, W.   & Fernández-Borges, N. et al.​ (2017) 
    Acta Neuropathologica Communication, 5(35) pp. 1​-20​.​ DOI: https://doi.org/10.1186/s40478-017-0431-y 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration​
    Zhang, J.-N. ; Michel, U. ; Lenz, C. ; Friedel, C. C.; Köster, S. ; D'Hedouville, Z. & Tönges, L.  et al.​ (2016) 
    Scientific Reports, 6 art. 37050​.​ DOI: https://doi.org/10.1038/srep37050 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons​
    Koch, J. C. ; Bitow, F.; Haack, J.; D'Hedouville, Z.; Zhang, J.-N.; Tönges, L.   & Michel, U.  et al.​ (2015) 
    Cell Death and Disease, 6 art. e1811​.​ DOI: https://doi.org/10.1038/cddis.2015.169 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells​
    Koch, J. C. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Frontiers in Cellular Neuroscience, 8 art. 273​.​ DOI: https://doi.org/10.3389/fncel.2014.00273 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS​
    Koch, J. C. ; Tönges, L. ; Barski, E. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Cell Death and Disease, 5 art. e1225​.​ DOI: https://doi.org/10.1038/cddis.2014.191 
    ​Details  DOI  PMID  PMC  WoS 

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