Prof. Dr. Lars Tönges

Staff Status
exunigoe
 

1-39 of 39
 
The bibliographical data in your publication list are complete
You can correct existing data in the blue highlighted fields.To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
The bibliographic data in your publication list may be incomplete. You can
  • add any missing data in the fields marked in red or
  • correct existing data in the blue highlighted fields.
To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
Check/Uncheck all
  • 2020 Journal Article
    ​ ​TDP‐43 as structure‐based biomarker in amyotrophic lateral sclerosis​
    Beyer, L.; Günther, R. ; Koch, J. C. ; Klebe, S.; Hagenacker, T.; Lingor, P.   & Biesalski, A. et al.​ (2020) 
    Annals of Clinical and Translational Neurology8(1) pp. 271​-277​.​ DOI: https://doi.org/10.1002/acn3.51256 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Selenium speciation analysis in the cerebrospinal fluid of patients with Parkinson’s disease​
    Maass, F. ; Michalke, B.; Willkommen, D.; Schulte, C.; Tönges, L. ; Boerger, M.   & Zerr, I.  et al.​ (2020) 
    Journal of Trace Elements in Medicine and Biology57 pp. 126412​.​ DOI: https://doi.org/10.1016/j.jtemb.2019.126412 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease​
    Maass, F. ; Michalke, B.; Willkommen, D.; Leha, A. ; Schulte, C.; Tönges, L.   & Mollenhauer, B.  et al.​ (2020) 
    Neurobiology of Disease134 pp. 104677​.​ DOI: https://doi.org/10.1016/j.nbd.2019.104677 
    Details  DOI 
  • 2018 Journal Article
    ​ ​miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons​
    Roser, A.-E. ; Caldi Gomes, L.; Halder, R. ; Jain, G.; Maass, F. ; Tönges, L.   & Tatenhorst, L.  et al.​ (2018) 
    Molecular Therapy - Nucleic Acids11 pp. 9​-22​.​ DOI: https://doi.org/10.1016/j.omtn.2018.01.005 
    Details  DOI 
  • 2018 Journal Article
    ​ ​ROCK inhibition in models of neurodegeneration and its potential for clinical translation​
    Koch, J. C. ; Tatenhorst, L. ; Roser, A.-E. ; Saal, K.-A. ; Tönges, L.   & Lingor, P. ​ (2018) 
    Pharmacology & Therapeutics189 pp. 1​-21​.​ DOI: https://doi.org/10.1016/j.pharmthera.2018.03.008 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson's disease​
    Maass, F. ; Michalke, B.; Leha, A. ; Boerger, M. ; Zerr, I. ; Koch, J.-C.   & Tönges, L.  et al.​ (2018) 
    Journal of Neurochemistry145(4) pp. 342​-351​.​ DOI: https://doi.org/10.1111/jnc.14316 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation​
    Carboni, E. ; Tatenhorst, L. ; Tönges, L. ; Barski, E. ; Dambeck, V. ; Bähr, M.   & Lingor, P. ​ (2017) 
    NeuroMolecular Medicine19(2-3) pp. 309​-321​.​ DOI: https://doi.org/10.1007/s12017-017-8447-9 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset​
    Günther, R. ; Balck, A. ; Koch, J. C. ; Nientiedt, T.; Sereda, M. ; Bähr, M.   & Lingor, P.  et al.​ (2017) 
    Frontiers in pharmacology8 art. 17​.​ DOI: https://doi.org/10.3389/fphar.2017.00017 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​Altered Expression of Growth Associated Protein-43 and Rho Kinase in Human Patients with Parkinson's Disease​
    Saal, K.-A. ; Galter, D.; Roeber, S.; Bähr, M. ; Tönges, L.   & Lingor, P. ​ (2017) 
    Brain Pathology27(1) pp. 13​-25​.​ DOI: https://doi.org/10.1111/bpa.12346 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article | Research Paper | 
    ​ ​Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration​
    Zhang, J.-N. ; Michel, U. ; Lenz, C. ; Friedel, C. C.; Köster, S. ; D'Hedouville, Z. & Tönges, L.  et al.​ (2016) 
    Scientific Reports6 art. 37050​.​ DOI: https://doi.org/10.1038/srep37050 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease​
    Tatenhorst, L. ; Eckermann, K.; Dambeck, V. ; Fonseca-Ornelas, L.; Walle, H.; Lopes Da Fonseca, T. & Koch, J. C.  et al.​ (2016) 
    Acta Neuropathologica Communication4(1) art. 39​.​ DOI: https://doi.org/10.1186/s40478-016-0310-y 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper | 
    ​ ​Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons​
    Koch, J. C. ; Bitow, F.; Haack, J.; D'Hedouville, Z.; Zhang, J.-N.; Tönges, L.   & Michel, U.  et al.​ (2015) 
    Cell Death and Disease6 art. e1811​.​ DOI: https://doi.org/10.1038/cddis.2015.169 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo​
    Saal, K.-A. ; Koch, J. C. ; Tatenhorst, L. ; Szegő, É. M. ; Ribas, V. T. ; Michel, U.   & Bähr, M.  et al.​ (2015) 
    Neurobiology of Disease73 pp. 150​-162​.​ DOI: https://doi.org/10.1016/j.nbd.2014.09.013 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Rho Kinase Inhibition by Fasudil in the Striatal 6-Hydroxydopamine Lesion Mouse Model of Parkinson Disease​
    Tatenhorst, L. ; Tönges, L. ; Saal, K.-A. ; Koch, J. C. ; Szegő, É. M. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Journal of Neuropathology and Experimental Neurology73(8) pp. 770​-779​.​ DOI: https://doi.org/10.1097/nen.0000000000000095 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease​
    Tönges, L. ; Szegö, E. M. ; Hause, P.; Saal, K.-A. ; Tatenhorst, L. ; Koch, J. C.   & D'Hedouville, Z. et al.​ (2014) 
    Frontiers in Aging Neuroscience6 art. UNSP 239​.​ DOI: https://doi.org/10.3389/fnagi.2014.00239 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Rho Kinase Inhibition Modulates Microglia Activation and Improves Survival in a Model of Amyotrophic Lateral Sclerosis​
    Tönges, L. ; Günther, R. ; Suhr, M. ; Jansen, J.; Balck, A. ; Saal, K.-A.   & Barski, E.  et al.​ (2014) 
    Glia62(2) pp. 217​-232​.​ DOI: https://doi.org/10.1002/glia.22601 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS​
    Koch, J. C. ; Tönges, L. ; Barski, E. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Cell Death and Disease5 art. e1225​.​ DOI: https://doi.org/10.1038/cddis.2014.191 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells​
    Koch, J. C. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Frontiers in Cellular Neuroscience8 art. 273​.​ DOI: https://doi.org/10.3389/fncel.2014.00273 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice​
    Günther, R. ; Saal, K.-A. ; Suhr, M. ; Scheer, D.; Koch, J. C. ; Bähr, M.   & Lingor, P.  et al.​ (2014) 
    Frontiers in Neuroscience8 art. 304​.​ DOI: https://doi.org/10.3389/fnins.2014.00304 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro​
    Koch, J. C. ; Solis, G. P.; Bodrikov, V.; Michel, U. ; Haralampieva, D.; Shypitsyna, A. & Tönges, L.  et al.​ (2013) 
    Neurobiology of Disease51 pp. 168​-176​.​ DOI: https://doi.org/10.1016/j.nbd.2012.11.007 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease​
    Tönges, L. ; Frank, T. ; Tatenhorst, L. ; Saal, K. A. ; Koch, J. C. ; Szego, E. M.   & Bähr, M.  et al.​ (2012) 
    Brain135(11) pp. 3355​-3370​.​ DOI: https://doi.org/10.1093/brain/aws254 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper
    ​ ​Transduction of Neural Precursor Cells with TAT-Heat Shock Protein 70 Chaperone: Therapeutic Potential Against Ischemic Stroke after Intrastriatal and Systemic Transplantation​
    Doeppner, T. R. ; Ewert, T. A. S.; Tönges, L. ; Herz, J.; Zechariah, A.; Elali, A. & Ludwig, A.-K. et al.​ (2012) 
    STEM CELLS30(6) pp. 1297​-1310​.​ DOI: https://doi.org/10.1002/stem.1098 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper
    ​ ​Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)​
    Günther, R. ; Suhr, M. ; Koch, J. C. ; Bähr, M. ; Lingor, P.   & Tönges, L. ​ (2012) 
    Journal of Visualized Experiments,(61) art. e3936​.​ DOI: https://doi.org/10.3791/3936 
    Details  DOI  WoS 
  • 2012 Review | 
    ​ ​Axonal degeneration as a therapeutic target in the CNS​
    Lingor, P. ; Koch, J. C. ; Tönges, L.  & Bähr, M. ​ (2012)
    Cell and Tissue Research, 349​(1) pp. 289​-311​.​ DOI: https://doi.org/10.1007/s00441-012-1362-3 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​JNK Isoforms Differentially Regulate Neurite Growth and Regeneration in Dopaminergic Neurons In Vitro​
    Tönges, L. ; Planchamp, V. ; Koch, J.-C. ; Herdegen, T.; Bähr, M.   & Lingor, P. ​ (2011) 
    Journal of Molecular Neuroscience45(2) pp. 284​-293​.​ DOI: https://doi.org/10.1007/s12031-011-9519-1 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Imaging of rat optic nerve axons in vivo​
    Koch, J. C. ; Knöferle, J. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2011) 
    Nature Protocols6(12) pp. 1887​-1896​.​ DOI: https://doi.org/10.1038/nprot.2011.403 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Review | 
    ​ ​ROCKing regeneration: Rho kinase inhibition as molecular target for neurorestoration​
    Tönges, L. ; Koch, J.-C. ; Bähr, M.  & Lingor, P. ​ (2011)
    Frontiers in Molecular Neuroscience, 4​.​ DOI: https://doi.org/10.3389/fnmol.2011.00039 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo​
    Tönges, L. ; Ostendorf, T.; Lamballe, F.; Genestine, M.; Dono, R.; Koch, J.-C.   & Bähr, M.  et al.​ (2011) 
    Journal of Neurochemistry117(5) pp. 892​-903​.​ DOI: https://doi.org/10.1111/j.1471-4159.2011.07257.x 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​Mechanisms of acute axonal degeneration in the optic nerve in vivo​
    Knöferle, J. ; Koch, J. C. ; Ostendorf, T.; Michel, U. ; Planchamp, V. ; Vutova, P. & Tönges, L.  et al.​ (2010) 
    Proceedings of the National Academy of Sciences107(13) pp. 6064​-6069​.​ DOI: https://doi.org/10.1073/pnas.0909794107 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Letter Note
    ​ ​Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner​
    Koch, J. C. ; Knöferle, J. ; Tönges, L. ; Ostendorf, T.; Bähr, M.   & Lingor, P. ​ (2010) 
    Autophagy6(5) pp. 658​-659​.​ DOI: https://doi.org/10.4161/auto.6.5.12188 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP​
    Knöferle, J. ; Ramljak, S. ; Koch, J. C. ; Tönges, L. ; Asif, A. R. ; Michel, U.   & Wouters, F. S.  et al.​ (2010) 
    Neurobiology of Disease38(3) pp. 395​-404​.​ DOI: https://doi.org/10.1016/j.nbd.2010.02.011 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice​
    Doeppner, T. R. ; Nagel, F.; Dietz, G. P. H. ; Weise, J.; Tönges, L. ; Schwarting, S. & Bähr, M. ​ (2009) 
    Journal of Cerebral Blood Flow & Metabolism29(6) pp. 1187​-1196​.​ DOI: https://doi.org/10.1038/jcbfm.2009.44 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells​
    Bermel, C. ; Tönges, L. ; Planchamp, V. ; Gillardon, F.; Weishaupt, J. H. ; Dietz, G. P. H.   & Bähr, M.  et al.​ (2009) 
    Molecular and Cellular Neuroscience42(4) pp. 427​-437​.​ DOI: https://doi.org/10.1016/j.mcn.2009.09.005 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity​
    Planchamp, V. ; Bermel, C. ; Tönges, L. ; Ostendorf, T.; Kügler, S. ; Reed, J. C. & Kermer, P.  et al.​ (2008) 
    Brain131 pp. 2606​-2619​.​ DOI: https://doi.org/10.1093/brain/awn196 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells​
    Lingor, P. ; Tönges, L. ; Pieper, N. ; Bermel, C. ; Barski, E. ; Planchamp, V.   & Bähr, M. ​ (2008) 
    Brain131(1) pp. 250​-263​.​ DOI: https://doi.org/10.1093/brain/awm284 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease​
    Nagel, F.; Falkenburger, B. H.; Tönges, L. ; Kowsky, S.; Pöppelmeyer, C.; Schulz, J. B.   & Bähr, M.  et al.​ (2008) 
    Journal of Neurochemistry105(3) pp. 853​-864​.​ DOI: https://doi.org/10.1111/j.1471-4159.2007.05204.x 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Galectin-1 expression in human glioma cells: Modulation by ionizing radiation and effects on tumor cell proliferation and migration​
    Strik, H. M. ; Schmidt, K.; Lingor, P. ; Tönges, L. ; Kugler, W.; Nitsche, M.   & Rabinovich, G. A. et al.​ (2007) 
    Oncology Reports18(2) pp. 483​-488​.​ DOI: https://doi.org/10.3892/or.18.2.483 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Review
    ​ ​Hematopoietic cytokines - on the verge of conquering neurology​
    Tönges, L. ; Schlachetzki, J. C. M.; Weishaupt, J. H.  & Bähr, M. ​ (2007)
    Current Molecular Medicine, 7​(2) pp. 157​-170​.​ DOI: https://doi.org/10.2174/156652407780059186 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons​
    Tönges, L. ; Lingor, P. ; Egle, R.; Dietz, G. P. H. ; Fahr, A. & Bähr, M. ​ (2006) 
    RNA12(7) pp. 1431​-1438​.​ DOI: https://doi.org/10.1261/rna.2252206 
    Details  DOI  PMID  PMC  WoS 

Publication List

Type

Subtype

Date issued

Author

Subject

Peer-Reviewed

Organization

Language

Fulltext

Options

Citation Style

https://publications.goettingen-research-online.de URI: /cris/rp/rp20045
ID: 0000000
PREF: default TOKEN:

0

Sort

Issue Date
Title

Embed

JavaScript
Link

Export

Activate Export Mode
Deactivate Export Mode

Select some or all items (max. 800 for CSV/Excel) from the publications list, then choose an export format below.