Prof. Dr. Niels Grabe

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  • 2018 | Journal Article | Research Paper
    ​ ​High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer​
    Janikovits, J.; Müller, M.; Krzykalla, J.; Körner, S.; Echterdiek, F.; Lahrmann, B. & Grabe, N.  et al.​ (2018) 
    OncoImmunology, 7(2) art. e1390640​.​ DOI: https://doi.org/10.1080/2162402X.2017.1390640 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients​
    Halama, N.; Zoernig, I.; Berthel, A.; Kahlert, C.; Klupp, F.; Suarez-Carmona, M. & Suetterlin, T. et al.​ (2016) 
    Cancer Cell, 29(4) pp. 587​-601​.​ DOI: https://doi.org/10.1016/j.ccell.2016.03.005 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer​
    Echterdiek, F.; Janikovits, J.; Staffa, L.; Müller, M.; Lahrmann, B.; Frühschütz, M. & Hartog, B. et al.​ (2016) 
    OncoImmunology, 5(2) art. e1075692​.​ DOI: https://doi.org/10.1080/2162402X.2015.1075692 
    ​Details  DOI  PMID  PMC 
  • 2016 | Conference Paper
    ​ ​Abstract A085: Immune evasion and PD-1-positive T cell infiltration in DNA mismatch repair-deficient colorectal cancer​
    Kloor, M.; Janikovits, J.; Krzykalla, J.; Benner, A.; Grabe, N. ; Echterdiek, F. & Mueller, M. et al.​ (2016)
    pp. A085​-A085. ​Second CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival​, New York, NY. DOI: https://doi.org/10.1158/2326-6066.IMM2016-A085 
    ​Details  DOI 
  • 2015 | Journal Article | Research Paper
    ​ ​Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters​
    Staffa, L.; Echterdiek, F.; Nelius, N.; Benner, A.; Werft, W.; Lahrmann, B. & Grabe, N.  et al.​ (2015) 
    PLoS One, 10(3) art. e0121980​.​ DOI: https://doi.org/10.1371/journal.pone.0121980 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article | Research Paper
    ​ ​HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas​
    Kostareli, E.; Holzinger, D.; Bogatyrova, O.; Hielscher, T.; Wichmann, G.; Keck, M. & Lahrmann, B. et al.​ (2013) 
    The Journal of Clinical Investigation, 123(6) pp. 2488​-2501​.​ DOI: https://doi.org/10.1172/JCI67010 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | Research Paper
    ​ ​Expression analysis of aldehyde dehydrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy​
    Kahlert, C.; Gaitzsch, E.; Steinert, G.; Mogler, C.; Herpel, E.; Hoffmeister, M. & Jansen, L. et al.​ (2012) 
    Annals of Surgical Oncology, 19(13) pp. 4193​-4201​.​ DOI: https://doi.org/10.1245/s10434-012-2518-9 
    ​Details  DOI  PMID  PMC 
  • 2011 | Journal Article | Research Paper
    ​ ​Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy​
    Halama, N.; Michel, S.; Kloor, M.; Zoernig, I.; Benner, A.; Spille, A. & Pommerencke, T. et al.​ (2011) 
    Cancer Research, 71(17) pp. 5670​-5677​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-11-0268 
    ​Details  DOI  PMID  PMC 

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