Prof. Dr. Elisabeth Zeisberg

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  • 2023 | Journal Article | 
    ​ ​Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis​
    Kanwischer, L.; Xu, X.; Saifuddin, A. B.; Maamari, S.; Tan, X.; Alnour, F. & Tampe, B. et al.​ (2023) 
    Clinical Epigenetics, 15(1) art. 149​.​ DOI: https://doi.org/10.1186/s13148-023-01561-2 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus​
    Hulshoff, M. S.; Schellinger, I. N.; Xu, X.; Fledderus, J.; Rath, S. K.; Wong, F. C. & Maamari, S. et al.​ (2023) 
    Diabetology & Metabolic Syndrome, 15(1) art. 11​.​ DOI: https://doi.org/10.1186/s13098-022-00966-y 
    ​Details  DOI 
  • 2021 | Book Chapter
    ​ ​High-Fidelity CRISPR/Cas9-Based Gene-Specific​
    Xu, X.& Zeisberg, E. M. ​ (2021)
    In:​Bogdanovic, Ozren; Vermeulen, Michiel​ (Eds.), Methods in Molecular Biology TET Proteins and DNA Demethylation : Methods and Protocols pp. 195​-206. ​New York, NY: ​Springer US. DOI: https://doi.org/10.1007/978-1-0716-1294-1_11 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications​
    Xu, X.; Hulshoff, M. S.; Tan, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2020) 
    International Journal of Molecular Sciences, 21(9) pp. 3038​.​ DOI: https://doi.org/10.3390/ijms21093038 
    ​Details  DOI  PMID  PMC 
  • 2020 | Preprint
    ​ ​SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​
    Michurina, A.; Sakib, S.; Kerimoglu, C.; Krüger, D. M.; Kaurani, L.; Islam, R.& Centeno, T. P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.07.240853 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1​
    Wilhelmi, T.; Xu, X.; Tan, X.; Hulshoff, M. S.; Maamari, S.; Sossalla, S.   & Zeisberg, M.  et al.​ (2020) 
    Theranostics, 10(9) pp. 3905​-3924​.​ DOI: https://doi.org/10.7150/thno.38640 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​The axis of local cardiac endogenous Klotho-TGF-β1-Wnt signaling mediates cardiac fibrosis in human​
    Liu, Q.; Zhu, L.-J.; Waaga-Gasser, A. M.; Ding, Y.; Cao, M.; Jadhav, S. J. & Kirollos, S. et al.​ (2019) 
    Journal of Molecular and Cellular Cardiology, 136 pp. 113​-124​.​ DOI: https://doi.org/10.1016/j.yjmcc.2019.09.004 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Epigenetic Regulation of Endothelial-to-Mesenchymal Transition in Chronic Heart Disease​
    Hulshoff, M. S.; Xu, X.; Krenning, G. & Zeisberg, E. M. ​ (2018) 
    Arteriosclerosis, Thrombosis, and Vascular Biology, 38(9) pp. 1986​-1996​.​ DOI: https://doi.org/10.1161/ATVBAHA.118.311276 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper
    ​ ​Causal Connections From Chronic Kidney Disease to Cardiac Fibrosis​
    Hulshoff, M. S.; Rath, S. K.; Xu, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2018) 
    Seminars in nephrology, 38(6) pp. 629​-636​.​ DOI: https://doi.org/10.1016/j.semnephrol.2018.08.007 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Wilhelmi, T.; Hulshoff, M. S.; Saito, S. & Moser, T.  et al.​ (2018) 
    Nature Communications, 9(1) art. 3509​.​ DOI: https://doi.org/10.1038/s41467-018-05766-5 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​
    Tan, X.; Xu, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2016) 
    PLoS ONE, 11(1) art. e0147816​.​ DOI: https://doi.org/10.1371/journal.pone.0147816 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Endocardial Fibroelastosis Is Caused by Aberrant Endothelial to Mesenchymal Transition​
    Xu, X.; Friehs, I.; Hu, T. Z.; Melnychenko, I.; Tampe, B. ; Alnour, F.   & Iascone, M. et al.​ (2015) 
    Circulation Research, 116(5) pp. 857​-866​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.116.305629 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice​
    Gogiraju, R.; Xu, X.; Bochenek, M. L.; Steinbrecher, J. H.; Lehnart, S. E. ; Wenzel, P. & Kessel, M.  et al.​ (2015) 
    Journal of the American Heart Association, 4(2) art. e001770​.​ DOI: https://doi.org/10.1161/JAHA.115.001770 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper
    ​ ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Nyamsuren, G.; Liu, X.; Maier, L. S.   & Sossalla, S.  et al.​ (2015) 
    Cardiovascular Research, 105(3) pp. 279​-291​.​ DOI: https://doi.org/10.1093/cvr/cvv015 
    ​Details  DOI  PMID  PMC  WoS 

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