Prof. Dr. rer. nat. Mladen Tzvetkov

Name Card

Main Affiliation
 
Staff Status
unigoe
 

1-28 of 28
 
The bibliographical data in your publication list are complete
You can correct existing data in the blue highlighted fields.To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
The bibliographic data in your publication list may be incomplete. You can
  • add any missing data in the fields marked in red or
  • correct existing data in the blue highlighted fields.
To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.
Check/Uncheck all
  • 2022 | Journal Article | 
    ​ ​Kragl, Angelique, Janosch Schoon, Ana Tzvetkova, Christoph Wenzel, Martina Blaschke, Wolfgang Böcker, Heide Siggelkow, and Mladen Vassilev Tzvetkov. "Effects of HSD11B1 knockout and overexpression on local cortisol production and differentiation of mesenchymal stem cells​." ​Frontiers in Bioengineering and Biotechnology ​10 (2022): ​953034​. ​https://doi.org/10.3389/fbioe.2022.953034.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Vay, Manuela, Marleen Julia Meyer, Antje Blank, Gisela Skopp, Peter Rose, Mladen Vassilev Tzvetkov, and Gerd Mikus. "Oral Yohimbine as a New Probe Drug to Predict CYP2D6 Activity: Results of a Fixed-Sequence Phase I Trial​." ​Clinical Pharmacokinetics ​59, no. 7 (2020): ​927​-939​. ​https://doi.org/10.1007/s40262-020-00862-6.
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Mewes, Caspar, Tessa Alexander, Benedikt Büttner, José Hinz, Ayelet Alpert, Aron-F. Popov, Michael Ghadimi et al. "TIM-3 Genetic Variants Are Associated with Altered Clinical Outcome and Susceptibility to Gram-Positive Infections in Patients with Sepsis​." ​International Journal of Molecular Sciences ​21, no. 21 (2020): ​8318​. ​https://doi.org/10.3390/ijms21218318.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Jensen, Ole, Salim Ansari, Lukas Gebauer, Simon F. Müller, Kira A. A. T. Lowjaga, Joachim Geyer, Mladen V. Tzvetkov, and Jürgen Brockmöller. "A double-Flp-in method for stable overexpression of two genes​." ​Scientific Reports ​10, no. 1 (2020): . ​https://doi.org/10.1038/s41598-020-71051-5.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Matthaei, Johannes, Wagner Hugo Bonat, Reinhold Kerb, Mladen Vassilev Tzvetkov, Jakob Strube, Stefanie Brunke, Cordula Sachse-Seeboth et al. "Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans​." ​Frontiers in Genetics ​11 (2020): . ​https://doi.org/10.3389/fgene.2020.00944.
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Jensen, Ole, Muhammad Rafehi, Mladen Vassilev Tzvetkov, and Jürgen Brockmöller. "Stereoselective cell uptake of adrenergic agonists and antagonists by organic cation transporters​." ​Biochemical Pharmacology ​171 (2020): ​113731​. ​https://doi.org/10.1016/j.bcp.2019.113731.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Meyer, Marleen J., Viktoria E. Neumann, Hannah Rosa Friesacher, Barbara Zdrazil, Jürgen Brockmöller, and Mladen V. Tzvetkov. "Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1​." ​Journal of Medicinal Chemistry ​62, no. 21 (2019): ​9890​-9905​. ​https://doi.org/10.1021/acs.jmedchem.9b01301.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​CHEN, Jia-Yin, Jürgen Brockmöller, Mladen V. Tzvetkov, Li-Jun Wang, and Xi-Jing Chen. "An in vitro study on interaction of anisodine and monocrotaline with organic cation transporters of the SLC22 and SLC47 families​." ​Chinese Journal of Natural Medicines ​17, no. 7 (2019): ​490​-497​. ​https://doi.org/10.1016/S1875-5364(19)30070-6.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Matthaei, Johannes, Tina Seitz, Ole Jensen, Annabelle Tann, Thomas Prukop, Sina Tadjerpisheh, Jürgen Brockmöller, and Mladen V. Tzvetkov. "OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil​." ​Clinical Pharmacology and Therapeutics ​105, no. 1 (2019): ​190​-200​. ​https://doi.org/10.1002/cpt.1128.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Jensen, Ole, Johannes Matthaei, Felix Blome, Matthias Schwab, Mladen V. Tzvetkov, and Jürgen Brockmöller. "Variability and heritability of thiamine pharmacokinetics with focus on OCT1 effects on membrane transport and pharmacokinetics in humans​." ​Clinical Pharmacology and Therapeutics ​107, no. 3 (2019): ​628​-638​. ​https://doi.org/10.1002/cpt.1666.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Runzheimer, Julius, Caspar Mewes, Benedikt Büttner, José Maria Hinz, Aron-Frederik Popov, Michael B. Ghadimi, Katalin Kristof et al. "Lack of an Association between the Functional Polymorphism TREM-1 rs2234237 and the Clinical Course of Sepsis among Critically Ill Caucasian Patients-A Monocentric Prospective Genetic Association Study​." ​Journal of Clinical Medicine ​8, no. 3 (2019): ​301​. ​https://doi.org/10.3390/jcm8030301.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Mewes, Caspar, Benedikt Büttner, José Maria Hinz, Ayelet Alpert, Aron-Frederik Popov, Michael B. Ghadimi, Tim Beißbarth et al. "CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis​." ​Journal of Clinical Medicine ​8, no. 1 (2019): ​70​. ​https://doi.org/10.3390/jcm8010070.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Rafehi, Muhammad, Frank Faltraco, Johannes Matthaei, Thomas Prukop, Ole Jensen, Aileen Grytzmann, Ralf Günter Berger et al. "Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A​." ​Frontiers in Pharmacology ​10 (2019): ​1297​. ​https://doi.org/10.3389/fphar.2019.01297.
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Gorboulev, Valentin, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller, and Hermann Koepsell. "Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake​." ​Molecular Pharmacology ​93, no. 4 (2018): ​402​-415​. ​https://doi.org/10.1124/mol.117.110767.
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Bokelmann, Kristin, Jürgen Brockmöller, and Mladen Tzvetkov. "Impact of Promoter Polymorphisms on the Transcriptional Regulation of the Organic Cation Transporter OCT1 (SLC22A1)​." ​Journal of Personalized Medicine ​8, no. 4 (2018): ​42​. ​https://doi.org/10.3390/jpm8040042.
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Mewes, Caspar, Benedikt Büttner, José Maria Hinz, Ayelet Alpert, Aron-Frederik Popov, Michael B. Ghadimi, Tim Beißbarth et al. "The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis​." ​Scientific Reports ​8, no. 1 (2018): . ​https://doi.org/10.1038/s41598-018-33246-9.
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Hinz, José Maria, Benedikt Büttner, Fabian Kriesel, Maximilian Steinau, Aron-Frederik Popov, Michael B. Ghadimi, Tim Beißbarth, Mladen Vassilev Tzvetkov, Ingo Bergmann, and Ashham Mansur. "The FER rs4957796 TT genotype is associated with unfavorable 90-day survival in Caucasian patients with severe ARDS due to pneumonia.​." ​Scientific reports ​7, no. 1 (2017): ​9887​. ​https://doi.org/10.1038/s41598-017-08540-7.
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Tzvetkov, Mladen V. "OCT1 pharmacogenetics in pain management: is a clinical application within reach?​." ​Pharmacogenomics ​18, no. 16 (2017): ​1515​-1523​. ​https://doi.org/10.2217/pgs-2017-0095.
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Tzvetkov, Mladen V., Johannes Matthaei, Sherin Pojar, Frank Faltraco, Sabrina Vogler, Thomas Prukop, Tina Seitz, and Jürgen Brockmöller. "Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency​." ​Clinical Pharmacology & Therapeutics ​103, no. 5 (2017): ​868​-878​. ​https://doi.org/10.1002/cpt.812.
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Meyer, Marleen Julia, Tina Seitz, Jürgen Brockmöller, and Mladen Vassilev Tzvetkov. "Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine​." ​PLOS ONE ​12, no. 12 (2017): ​e0189521​. ​https://doi.org/10.1371/journal.pone.0189521.
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Matthaei, J., M. V. Tzvetkov, J. Strube, D. Sehrt, C. Sachse-Seeboth, J. B. Hjelmborg, S. Möller et al. "Heritability of Caffeine Metabolism: Environmental Effects Masking Genetic Effects on CYP1A2 Activity but Not on NAT2​." ​Clinical Pharmacology & Therapeutics ​100, no. 6 (2016): ​606​-616​. ​https://doi.org/10.1002/cpt.444.
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Mansur, Ashham, Maximilian Steinau, Aron-Frederik Popov, Sinisa Milenovic, Christian Bireta, Alexander Weymann, Hanna Schotola et al. "Genetic Polymorphisms in Endothelin-1 as Predictors for Long-Term Survival and the Cardiac Index in Patients Undergoing On-Pump Cardiac Surgery​." ​PLoS ONE ​10, no. 6 (2015): ​e0131155​. ​https://doi.org/10.1371/journal.pone.0131155.
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Reichwagen, Annegret, Marita Ziepert, Markus Kreuz, Ute Gödtel-Armbrust, Tanja Rixecker, Viola Poeschel, Mohammad Reza Toliat et al. "Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma​." ​Pharmacogenomics ​16, no. 4 (2015): ​361​-372​. ​https://doi.org/10.2217/PGS.14.179.
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Mansur, Ashham, Benjamin Liese, Maximilian Steinau, Michael B. Ghadimi, Ingo Bergmann, Mladen Vassilev Tzvetkov, Aron-Frederik Popov, Tim Beißbarth, Martin Bauer, and José Maria Hinz. "The CD14 rs2569190 TT Genotype Is Associated with an Improved 30-Day Survival in Patients with Sepsis: A Prospective Observational Cohort Study​." ​PLoS ONE ​10, no. 5 (2015): ​e0127761​. ​https://doi.org/10.1371/journal.pone.0127761.
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Matthaei, Johannes, Jürgen Brockmöller, Mladen Vassilev Tzvetkov, Daniel Sehrt, Cordula Sachse-Seeboth, Jakob B. Hjelmborg, S. Möller et al. "Heritability of Metoprolol and Torsemide Pharmacokinetics​." ​Clinical Pharmacology & Therapeutics ​98, no. 6 (2015): ​611​-621​. ​https://doi.org/10.1002/cpt.258.
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​Kuehne, Annett, Mladen Vassilev Tzvetkov, Yohannes Hagos, Hermann Lage, Gerhard Burckhardt, and Juergen Brockmoeller. "Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines​." ​Biochemical Pharmacology ​78, no. 1 (2009): ​45​-53​. ​https://doi.org/10.1016/j.bcp.2009.03.026.
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Wojnowski, Leszek, Bettina Kulle, Markus Schirmer, Georg Schlüter, Albrecht Schmidt, Albert Rosenberger, Stefan Vonhof et al. "NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity​." ​Circulation ​112, no. 24 (2005): ​3754​-3762​. ​https://doi.org/10.1161/CIRCULATIONAHA.105.576850.
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Kulle, Bettina, M Schirmer, Mohammad Reza Toliat, A. Suk, C. Becker, Mladen Tzvetkov, Jürgen Brockmöller et al. "Application of genomewide SNP arrays for detection of simulated susceptibility loci​." ​Human Mutation ​25, no. 6 (2005): ​557​-565​. ​https://doi.org/10.1002/humu.20174.
    ​Details  DOI  PMID  PMC  WoS 

Publication List

All Articles (Book & Journal) Articles & Preprints Papers (Journal & Conference)

Type

Subtype

Date issued

Author

Peer-Reviewed

Organization

Language

Fulltext

Options

Citation Style

GRO View APA Chicago MLA Vancouver
https://publications.goettingen-research-online.de URI: /cris/rp/rp22693
ID: 0000000
PREF: chicago TOKEN:

0

Sort

Issue Date
ASC DESC
Title
ASC DESC

Embed

JavaScript
Link

Export

Activate Export Mode
Deactivate Export Mode

Select some or all items (max. 800 for CSV/Excel) from the publications list, then choose an export format below.