Prof. Dr. Lutz Ackermann

 
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  • 2023 Preprint | 
    ​ ​Enantioselective cobaltaelectro-catalyzed C–H activations enabled by hydrogen evolution​
    Ackermann, L. ; Münchow, T. von; Dana, S.; Xu, Y.& Yuan, B.​ (2023). DOI: https://doi.org/10.26434/chemrxiv-2023-dzw3d 
    Details  DOI 
  • 2023 Journal Article | 
    ​ ​Site-selective electrochemical carboxylation of aromatic C(sp2)–H bonds with CO2​
    Zhao, R.; Surke, M.; Lin, Z.; Alsalme, A. & Ackermann, L. ​ (2023) 
    Current Research in Green and Sustainable Chemistry7 pp. 100377​.​ DOI: https://doi.org/10.1016/j.crgsc.2023.100377 
    Details  DOI 
  • 2023 Journal Article | 
    ​ ​Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification​
    Lin, Z.; Dhawa, U.; Hou, X.; Surke, M.; Yuan, B.; Li, S.-W. & Liou, Y.-C. et al.​ (2023) 
    Nature Communications14(1).​ DOI: https://doi.org/10.1038/s41467-023-39747-0 
    Details  DOI 
  • 2023 Journal Article | 
    ​ ​Late-stage peptide labeling with near-infrared fluorogenic nitrobenzodiazoles by manganese-catalyzed C–H activation​
    Oyama, T. ; Mendive-Tapia, L.; Cowell, V.; Kopp, A.; Vendrell, M. & Ackermann, L. ​ (2023) 
    Chemical Science14(21) pp. 5728​-5733​.​ DOI: https://doi.org/10.1039/D3SC01868G 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Remote C−H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta‐C‐Aryl Glycosides​
    Wu, J.; Kaplaneris, N.; Pöhlmann, J.; Michiyuki, T.; Yuan, B. & Ackermann, L. ​ (2022) 
    Angewandte Chemie International Edition61(42) art. anie.202208620​.​ DOI: https://doi.org/10.1002/anie.202208620 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Chemo‐ and Site‐Selective Electro‐Oxidative Alkane Fluorination by C(sp3)−H Cleavage​
    Stangier, M.; Scheremetjew, A. & Ackermann, L. ​ (2022) 
    Chemistry – A European Journal28(60).​ DOI: https://doi.org/10.1002/chem.202201654 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Three-component carboacylation of alkenes via cooperative nickelaphotoredox catalysis​
    Wang, D. & Ackermann, L. ​ (2022) 
    Chemical Science13(24) pp. 7256​-7263​.​ DOI: https://doi.org/10.1039/D2SC02277J 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation​
    Berger, A.; Knak, T.; Kiffe-Delf, A.-L.; Mudrovcic, K.; Singh, V.; Njoroge, M. & Burckhardt, B. B. et al.​ (2022) 
    Pharmaceuticals15(8) pp. 984​.​ DOI: https://doi.org/10.3390/ph15080984 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Ruthenium(II)/Imidazolidine Carboxylic Acid‐Catalyzed C−H Alkylation for Central and Axial Double Enantio‐Induction​
    Li, Y.; Liou, Y.; Oliveira, J. C. A. & Ackermann, L. ​ (2022) 
    Angewandte Chemie International Edition61(47) art. anie.202212595​.​ DOI: https://doi.org/10.1002/anie.202212595 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo​
    De Oliveira, T.; Goldhardt, T.; Edelmann, M.; Rogge, T. ; Rauch, K. ; Kyuchukov, N. D. & Menck, K.  et al.​ (2021) 
    Cancers13(5) pp. 1011​.​ DOI: https://doi.org/10.3390/cancers13051011 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​Electrooxidative dearomatization of biaryls: synthesis of tri- and difluoromethylated spiro[5.5]trienones​
    Zhang, Y.; Ma, C.; Struwe, J.; Feng, J.; Zhu, G. & Ackermann, L. ​ (2021) 
    Chemical Science12(29) pp. 10092​-10096​.​ DOI: https://doi.org/10.1039/D1SC02682H 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​Electroreductive Nickel‐Catalyzed Thiolation: Efficient Cross‐Electrophile Coupling for C−S Formation​
    Ang, N. W. J. & Ackermann, L. ​ (2021) 
    Chemistry – A European Journal27(15) pp. 4883​-4887​.​ DOI: https://doi.org/10.1002/chem.202005449 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​Photoinduced Heterogeneous C−H Arylation by a Reusable Hybrid Copper Catalyst​
    Choi, I.; Müller, V.; Lole, G.; Köhler, R.; Karius, V. ; Viöl, W. & Jooss, C.  et al.​ (2020) 
    Chemistry – A European Journal26(16) pp. 3509​-3514​.​ DOI: https://doi.org/10.1002/chem.202000192 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism​
    Wild, M.; Hahn, F.; Grau, B.; Herrmann, L.; Niesar, A.; Schütz, M. & Lorion, M. M.  et al.​ (2020) 
    International Journal of Molecular Sciences21(15) pp. 5578​.​ DOI: https://doi.org/10.3390/ijms21155578 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Recyclable Ruthenium Catalyst for Distal meta ‐C−H Activation​
    Choi, I.; Müller, V.; Wang, Y.; Xue, K.; Kuniyil, R.; Andreas, L. B. & Karius, V.  et al.​ (2020) 
    Chemistry – A European Journal26(66) pp. 15290​-15297​.​ DOI: https://doi.org/10.1002/chem.202003622 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Electrochemical Selenation/Cyclization of Quinones: A Rapid, Green and Efficient Access to Functionalized Trypanocidal and Antitumor Compounds​
    Kharma, A.; Jacob, C.; Bozzi, Í. A. O.; Jardim, G. A. M.; Braga, A. L.; Salomão, K. & Gatto, C. C. et al.​ (2020) 
    European Journal of Organic Chemistry2020(29) pp. 4474​-4486​.​ DOI: https://doi.org/10.1002/ejoc.202000216 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​(Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses​
    Çapcı, A.; Lorion, M. M. ; Mai, C.; Hahn, F.; Hodek, J.; Wangen, C. & Weber, J. et al.​ (2020) 
    Chemistry – A European Journal26(52) pp. 12019​-12026​.​ DOI: https://doi.org/10.1002/chem.202001803 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Cobalta‐Electrocatalyzed C−H Activation in Biomass‐Derived Glycerol: Powered by Renewable Wind and Solar Energy​
    Meyer, T. H. ; Chesnokov, G. A. & Ackermann, L. ​ (2020) 
    ChemSusChem13(4) pp. 668​-671​.​ DOI: https://doi.org/10.1002/cssc.202000057 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Electrochemical Access to Aza‐Polycyclic Aromatic Hydrocarbons: Rhoda‐Electrocatalyzed Domino Alkyne Annulations​
    Kong, W.; Shen, Z.; Finger, L. H. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(14) pp. 5551​-5556​.​ DOI: https://doi.org/10.1002/anie.201914775 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Nickela‐electrocatalyzed C−H Alkoxylation with Secondary Alcohols: Oxidation‐Induced Reductive Elimination at Nickel(III)​
    Zhang, S.; Struwe, J.; Hu, L. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(8) pp. 3178​-3183​.​ DOI: https://doi.org/10.1002/anie.201913930 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Electrochemical C−H Amidation of Heteroarenes with N ‐Alkyl Sulfonamides in Aqueous Medium​
    Zhang, Y.; Lin, Z. & Ackermann, L. ​ (2020) 
    Chemistry – A European Journal27(1) pp. 242​-246​.​ DOI: https://doi.org/10.1002/chem.202004229 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Photo‐Induced Ruthenium‐Catalyzed C−H Arylations at Ambient Temperature​
    Korvorapun, K. ; Struwe, J.; Kuniyil, R.; Zangarelli, A.; Casnati, A.; Waeterschoot, M. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(41) pp. 18103​-18109​.​ DOI: https://doi.org/10.1002/anie.202003035 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Nickela‐electrocatalyzed Mild C−H Alkylations at Room Temperature​
    Samanta, R. C.; Struwe, J. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(33) pp. 14154​-14159​.​ DOI: https://doi.org/10.1002/anie.202004958 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Evolution of High‐Valent Nickela‐Electrocatalyzed C−H Activation: From Cross(‐Electrophile)‐Couplings to Electrooxidative C−H Transformations​
    Zhang, S.; Samanta, R. C.; Del Vecchio, A. & Ackermann, L. ​ (2020) 
    Chemistry – A European Journal26(48) pp. 10936​-10947​.​ DOI: https://doi.org/10.1002/chem.202001318 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​C7‐Indole Amidations and Alkenylations by Ruthenium(II) Catalysis​
    Choi, I.; Messinis, A. M. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(30) pp. 12534​-12540​.​ DOI: https://doi.org/10.1002/anie.202006164 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Enantioselective Pallada‐Electrocatalyzed C−H Activation by Transient Directing Groups: Expedient Access to Helicenes​
    Dhawa, U.; Tian, C.; Wdowik, T.; Oliveira, J. C. A.; Hao, J. & Ackermann, L. ​ (2020) 
    Angewandte Chemie International Edition59(32) pp. 13451​-13457​.​ DOI: https://doi.org/10.1002/anie.202003826 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Metallaelectro-Catalyzed C–H Activation by Weak Coordination​
    Qiu, Y.; Struwe, J. & Ackermann, L. ​ (2019) 
    Synlett30(10) pp. 1164​-1173​.​ DOI: https://doi.org/10.1055/s-0037-1611568 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Visible-Light-Induced Decarboxylative C–H Adamantylation of Azoles at Ambient Temperature​
    Koeller, J.; Gandeepan, P. & Ackermann, L. ​ (2019) 
    Synthesis51(05) pp. 1284​-1292​.​ DOI: https://doi.org/10.1055/s-0037-1611633 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​π‐Extended Polyaromatic Hydrocarbons by Sustainable Alkyne Annulations through Double C−H/N−H Activation​
    Gońka, E.; Yang, L.; Steinbock, R.; Pesciaioli, F.; Kuniyil, R. & Ackermann, L. ​ (2019) 
    Chemistry – A European Journal25(71) pp. 16246​-16250​.​ DOI: https://doi.org/10.1002/chem.201905023 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Iron‐Electrocatalyzed C−H Arylations: Mechanistic Insights into Oxidation‐Induced Reductive Elimination for Ferraelectrocatalysis​
    Zhu, C.; Stangier, M.; Oliveira, J. C. A.; Massignan, L. & Ackermann, L. ​ (2019) 
    Chemistry – A European Journal25(71) pp. 16382​-16389​.​ DOI: https://doi.org/10.1002/chem.201904018 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Late-stage peptide C–H alkylation for bioorthogonal C–H activation featuring solid phase peptide synthesis​
    Schischko, A.; Kaplaneris, N.; Rogge, T. ; Sirvinskaite, G.; Son, J. & Ackermann, L. ​ (2019) 
    Nature Communications10(1).​ DOI: https://doi.org/10.1038/s41467-019-11395-3 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Weakly-coordinating N -oxide and carbonyl groups for metal-catalyzed C–H activation: the case of A-ring functionalization​
    da Silva Júnior, E. N.; Jardim, G. A. M.; Gomes, R. S.; Liang, Y.-F. & Ackermann, L. ​ (2018) 
    Chemical Communications54(54) pp. 7398​-7411​.​ DOI: https://doi.org/10.1039/C8CC03147A 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Nickel-catalyzed reductive thiolation and selenylation of unactivated alkyl bromides​
    Fang, Y.; Rogge, T. ; Ackermann, L. ; Wang, S.-Y. & Ji, S.-J.​ (2018) 
    Nature Communications9(1).​ DOI: https://doi.org/10.1038/s41467-018-04646-2 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Ruthenium-catalyzed C–H oxygenation of quinones by weak O-coordination for potent trypanocidal agents​
    Dias, G. G.; Rogge, T. ; Kuniyil, R.; Jacob, C.; Menna-Barreto, R. F. S.; da Silva Júnior, E. N. & Ackermann, L. ​ (2018) 
    Chemical Communications54(91) pp. 12840​-12843​.​ DOI: https://doi.org/10.1039/C8CC07572G 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Ruthenium(IV) Intermediates in C−H Activation/Annulation by Weak O ‐Coordination​
    Liang, Y.-F.; Yang, L.; Rogge, T.   & Ackermann, L. ​ (2018) 
    Chemistry: a European Journal24(62) pp. 16548​-16552​.​ DOI: https://doi.org/10.1038/s41467-018-03341-6 
    Details  DOI 

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