Prof. Dr. med. Jochen Gaedcke

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  • 2017 | Journal Article | Research Paper | 
    ​ ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​
    Jo, P. ; Azizian, A. ; Salendo, J. ; Kramer, F. ; Bernhardt, M. ; Wolff, H. A.   & Gruber, J. et al.​ (2017) 
    International Journal of Molecular Sciences, 18(6) art. 1140​.​ DOI: https://doi.org/10.3390/ijms18061140 
    ​Details  DOI  WoS 
  • 2017 | Journal Article
    ​ ​Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling​
    Emons, G. ; Spitzner, M. ; Reineke, S. ; Möller, J.; Auslander, N.; Kramer, F.   & Hu, Y. et al.​ (2017) 
    Molecular Cancer Research, 15(11) pp. 1481​-1490​.​ DOI: https://doi.org/10.1158/1541-7786.MCR-17-0205 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | 
    ​ ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​
    Jo, P. ; Nietert, M. M. ; Gusky, L.; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016) 
    Scientific Reports, 6 art. 35589​.​ DOI: https://doi.org/10.1038/srep35589 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer​
    Azizian, A. ; Kramer, F. ; Jo, P. ; Wolff, H. A. ; Beißbarth, T. ; Skarupke, R. & Bernhardt, M.  et al.​ (2015) 
    World Journal of Surgery, 39(9) pp. 2329​-2335​.​ DOI: https://doi.org/10.1007/s00268-015-3083-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Conference Abstract
    ​ ​Targeting STAT3 as a therapeutic strategy to sensitize colorectal cancer to chemoradiotherapy​
    Grade, M. ; Spitzner, M. ; Roesler, B.; Bielfeld, C.; Gaedcke, J. ; Wolff, H. A.   & Beißbarth, T.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Journal Article
    ​ ​STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Emons, G. ; Gaedcke, J. ; Wolff, H. A.   & Rave-Fränk, M.  et al.​ (2014) 
    International Journal of Cancer, 134(4) pp. 997​-1007​.​ DOI: https://doi.org/10.1002/ijc.28429 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Conference Paper
    ​ ​Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g​
    Salendo, J. ; Spitzner, M. ; Kramer, F. ; Zhang, X.; Jo, P. ; Wolff, H. A.   & Kitz, J.  et al.​ (2013)
    Radiotherapy and Oncology, 108(3) pp. 451​-457. ​13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology​, Ermatingen, SWITZERLAND.
    Clare​: Elsevier Ireland Ltd. DOI: https://doi.org/10.1016/j.radonc.2013.06.032 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Frequency of HER-2 Positivity in Rectal Cancer and Prognosis​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Roedel, C.; Nietert, M. M.   & Homayounfar, K.  et al.​ (2013) 
    American Journal of Surgical Pathology, 37(4) pp. 522​-531​.​ DOI: https://doi.org/10.1097/PAS.0b013e318272ff4d 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Conference Abstract
    ​ ​The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a beta-catenin independent manner​
    Grade, M. ; Eimer, C. ; Emons, G. ; Kendziorra, E.; Spitzner, M. ; Gaedcke, J.   & Wolff, H. A.  et al.​ (2012)
    Cancer Research, 72 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2012-5729 
    ​Details  DOI  WoS 
  • 2012 | Journal Article
    ​ ​Acute Toxicity of Radiochemotherapy in Rectal Cancer Patients: A Risk Particularly for Carriers of the TGFB1 Pro25 variant​
    Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Herrmann, M. K. A.; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2012) 
    International Journal of Radiation Oncology*Biology*Physics, 83(1) pp. 149​-157​.​ DOI: https://doi.org/10.1016/j.ijrobp.2011.05.063 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer​
    Jo, P. ; Jung, K. ; Grade, M. ; Conradi, L.-C. ; Wolff, H. A. ; Kitz, J.   & Becker, H. et al.​ (2012) 
    Surgery, 151(4) pp. 564​-570​.​ DOI: https://doi.org/10.1016/j.surg.2011.08.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​TGFB1 Pro25 allele as a risk marker for higher-grade acute Organ toxicity (CTC >= Grad2) during neoadjuvant Chemoradiotherapy in patients with locally advanced Rectal cancer (UICC Stage II/III)​
    Christiansen, H.; Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2011)
    Strahlentherapie und Onkologie, 187 , Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2011 | Journal Article
    ​ ​Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy​
    Kendziorra, E.; Ahlborn, K.; Spitzner, M. ; Rave-Fränk, M. ; Emons, G. ; Gaedcke, J.   & Kramer, F.  et al.​ (2011) 
    Carcinogenesis, 32(12) pp. 1824​-1831​.​ DOI: https://doi.org/10.1093/carcin/bgr222 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Schirmer, M. A. ; Jo, P. ; Obermeyer, C. & Wolff, H. A.  et al.​ (2010) 
    Radiotherapy and Oncology, 94(1) pp. 76​-81​.​ DOI: https://doi.org/10.1016/j.radonc.2009.10.001 
    ​Details  DOI  PMID  PMC  WoS 

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