Prof. Dr. med. Michael Ghadimi

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Diefenhardt M, Schlenska-Lange A, Kuhnt T, Kirste S, Piso P, Bechstein WO, et al. ​Total Neoadjuvant Therapy for Rectal Cancer in the CAO/ARO/AIO-12 Randomized Phase 2 Trial: Early Surrogate Endpoints Revisited​. ​​Cancers. ​2022;​14​(15). ​doi:10.3390/cancers14153658. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper
    ​ ​Bösch F, Ghadimi M, Angele MK. ​Personalisierte Resektionsverfahren bei neuroendokrinen Neoplasien des Pankreas​. ​​Zentralblatt für Chirurgie. ​2022;​147​(03):​​264​-269​. ​doi:10.1055/a-1823-1275. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Fleischmann M, Diefenhardt M, Nicolas AM, Rödel F, Ghadimi M, Hofheinz, Ralf-Dieter, et al. ​ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group​. ​​Clinical and Translational Radiation Oncology. ​2022;​34​:​​99​-106​. ​doi:10.1016/j.ctro.2022.04.003. 
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  • 2022 | Journal Article | 
    ​ ​Hettler M, Kitz J, Hosseini ASA, Guhlich M, Panahi B, Ernst J, et al. ​Comparing Apparent Diffusion Coefficient and FNCLCC Grading to Improve Pretreatment Grading of Soft Tissue Sarcoma—A Translational Feasibility Study on Fusion Imaging​. ​​Cancers. ​2022;​14​(17):​​4331​. ​doi:10.3390/cancers14174331. 
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  • 2022 | Journal Article | 
    ​ ​Azizian A, Koenig A, Ghadimi M. ​Treatment options of metastatic and nonmetastatic VIPoma: a review​. ​​Langenbeck's Archives of Surgery. ​2022;. ​doi:10.1007/s00423-022-02620-7. 
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  • 2022 | Journal Article | 
    ​ ​Diefenhardt M, Martin D, Ludmir EB, Fleischmann M, Hofheinz, Ralf-Dieter, Ghadimi M, et al. ​Development and Validation of a Predictive Model for Toxicity of Neoadjuvant Chemoradiotherapy in Rectal Cancer in the CAO/ARO/AIO-04 Phase III Trial​. ​​Cancers. ​2022;​14​(18):​​4425​. ​doi:10.3390/cancers14184425. 
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  • 2022 | Journal Article | 
    ​ ​Kneist W, Ghadimi M, Runkel N, Moesta T, Coerper S, Benecke C, et al. ​Pelvic Intraoperative Neuromonitoring Prevents Dysfunction in Patients with Rectal Cancer: Results from a Multicenter, Randomized, Controlled Clinical Trial of a NEUROmonitoring System (NEUROS)​. ​​Annals of Surgery. ​2022;. ​doi:10.1097/SLA.0000000000005676. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Seufferlein T, Uhl W, Kornmann M, Algül H, Friess H, König A, et al. ​Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX) - a randomized phase II trial of the AIO pancreatic cancer group​. ​​Annals of Oncology. ​2022;. ​doi:10.1016/j.annonc.2022.09.161. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Reinecke J, Amanzada A, Elger F, Ghadimi M, Neesse A. ​A rare cause of upper gastrointestinal bleeding from a submucosal tumor​. ​​Endoscopic Ultrasound. ​2021;​10​(1):​​75​. ​doi:10.4103/eus.eus_75_20. 
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  • 2021 | Journal Article
    ​ ​Nöpel-Dünnebacke S, Conradi, Lena-Christin, Reinacher-Schick A, Ghadimi M. ​Einfluss der Molekularpathologie auf die onkologische Chirurgie des kolorektalen Karzinoms​. ​​Der Chirurg. ​2021;. ​doi:10.1007/s00104-021-01486-7. 
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  • 2021 | Journal Article
    ​ ​Kosmala R, Fokas E, Flentje M, Sauer R, Liersch T, Graeven U, et al. ​Quality of life in rectal cancer patients with or without oxaliplatin in the randomised CAO/ARO/AIO-04 phase 3 trial​. ​​European Journal of Cancer. ​2021;​144​:​​281​-290​. ​doi:10.1016/j.ejca.2020.11.029. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Ghadimi M, Reinacher-Schick A, Bläker H, Höffken K. ​State of the Art in der Therapie des Kolonkarzinoms​. ​​Der Onkologe. ​2021;​27​(3):​​192​-194​. ​doi:10.1007/s00761-020-00896-2. 
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  • 2021 | Journal Article | 
    ​ ​De Oliveira T, Goldhardt T, Edelmann M, Rogge T, Rauch K, Kyuchukov ND, et al. ​Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo​. ​​Cancers. ​2021;​13​(5):​​1011​. ​doi:10.3390/cancers13051011. 
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  • 2021 | Journal Article | 
    ​ ​Grade M, Ghadimi M. ​Personalmanagement und Leadership in der Chirurgie​. ​​Der Chirurg. ​2021;​92​(3):​​227​-231​. ​doi:10.1007/s00104-020-01345-x. 
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  • 2020 | Journal Article | Research Paper
    ​ ​Biggemann L, Uhlig J, Gliem N, Al-Bourini O, Wedi E, Ellenrieder V, et al. ​Assessment of esophageal motility disorders by real-time MRI​. ​​European Journal of Radiology. ​2020;​132​:​​109265​. ​doi:10.1016/j.ejrad.2020.109265. 
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  • 2020 | Journal Article | Research Paper
    ​ ​Hosseini ASA, Uhlig J, Streit U, Gliem N, Wedi E, Ellenrieder V, et al. ​Real-time MRI for dynamic assessment of gastroesophageal reflux disease: Comparison to pH-metry and impedance​. ​​European Journal of Radiology. ​2020;​125​. ​doi:10.1016/j.ejrad.2020.108856. 
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  • 2020 | Journal Article
    ​ ​Dusch N, Oldani M, Steffen T, Kitz J, Koenig U, Azizian A, et al. ​Intensified Histopathological Work-Up after Pancreatic Head Resection Reveals Relevant Prognostic Markers​. ​​Digestion. ​2020;:​​1​-9​. ​doi:10.1159/000504648. 
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  • 2020 | Journal Article
    ​ ​Nöpel-Dünnebacke S, Conradi, Lena-Christin, Reinacher-Schick A, Ghadimi M. ​Therapeutische Relevanz molekularer Marker beim kolorektalen Karzinom​. ​​Der Onkologe. ​2020;​26​(8):​​685​-697​. ​doi:10.1007/s00761-020-00777-8. 
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  • 2020 | Journal Article
    ​ ​Diefenhardt M, Ludmir EB, Hofheinz, Ralf-Dieter, Ghadimi M, Minsky BD, Rödel C, et al. ​Association of Sex With Toxic Effects, Treatment Adherence, and Oncologic Outcomes in the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trials of Rectal Cancer​. ​​JAMA Oncology. ​2020;​6​(2):​​294​. ​doi:10.1001/jamaoncol.2019.5102. 
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  • 2020 | Journal Article
    ​ ​von Heesen M, Ghadimi M. ​Chirurgische Resektion: offen, laparoskopisch, robotisch​. ​​Der Onkologe. ​2020;​27​(3):​​234​-244​. ​doi:10.1007/s00761-020-00865-9. 
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  • 2020 | Journal Article
    ​ ​Attenberger U, Rödel C, Ghadimi M, Piso P, Arnold D, Folprecht G, et al. ​Stellenwert und qualitative Voraussetzungen der Magnetresonanztomografie für die Therapieplanung beim lokal fortgeschrittenen Rektumkarzinom – Interdisziplinäre Empfehlungen​. ​​Zeitschrift für Gastroenterologie. ​2020;​58​(06):​​577​-582​. ​doi:10.1055/a-1085-6874. 
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  • 2020 | Journal Article
    ​ ​Sinn M, Liersch T, Riess H, Gellert K, Stübs P, Waldschmidt D, et al. ​CONKO-006: A randomised double-blinded phase IIb-study of additive therapy with gemcitabine + sorafenib/placebo in patients with R1 resection of pancreatic cancer – Final results​. ​​European Journal of Cancer. ​2020;​138​:​​172​-181​. ​doi:10.1016/j.ejca.2020.06.032. 
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  • 2020 | Journal Article
    ​ ​Sprenger T, Beißbarth T, Sauer R, Tschmelitsch J, Fietkau R, Hohenberger W, et al. ​The long-term influence of hospital and surgeon volume on local control and survival in the randomized German Rectal Cancer Trial CAO/ARO/AIO-94​. ​​Surgical Oncology. ​2020;​35​:​​200​-205​. ​doi:10.1016/j.suronc.2020.08.021. 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Diefenhardt M, Ludmir EB, Hofheinz, Ralf-Dieter, Ghadimi M, Minsky BD, Rödel C, et al. ​Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer​. ​​JAMA Oncology. ​2020;​6​(9):​​1416​. ​doi:10.1001/jamaoncol.2020.2394. 
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  • 2020 | Journal Article | 
    ​ ​Attenberger UI, Clasen S, Ghadimi M, Grosse U, Antoch G, Schreyer AG, et al. ​Importance and Qualitative Requirements of Magnetic Resonance Imaging for Therapy Planning in Rectal Cancer – Interdisciplinary Recommendations of AIO, ARO, ACO and the German Radiological Society​. ​​RöFo. ​2020;. ​doi:10.1055/a-1299-1807. 
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  • 2020 | Journal Article | 
    ​ ​Azizian A, Rühlmann F, Krause T, Bernhardt M, Jo P, König A, et al. ​CA19-9 for detecting recurrence of pancreatic cancer​. ​​Scientific Reports. ​2020;​10​(1). ​doi:10.1038/s41598-020-57930-x. 
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  • 2020 | Journal Article | 
    ​ ​Hoeppner J, Plum PS, Buhr H, Gockel I, Lorenz D, Ghadimi M, et al. ​Chirurgische Therapie des Ösophaguskarzinoms – Qualitätsindikatoren für Diagnostik und Therapie​. ​​Der Chirurg. ​2020;​92​(4):​​350​-360​. ​doi:10.1007/s00104-020-01267-8. 
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  • 2020 | Journal Article | 
    ​ ​Jo P, Bernhardt M, Nietert M, König A, Azizian A, Schirmer MA, et al. ​KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer​. ​​PLoS One. ​2020;​15​(10):​​e0239806​. ​doi:10.1371/journal.pone.0239806. 
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  • 2020 | Journal Article | Research Paper | 
    ​ ​Mewes C, Alexander T, Büttner B, Hinz J, Alpert A, Popov, Aron-F., et al. ​TIM-3 Genetic Variants Are Associated with Altered Clinical Outcome and Susceptibility to Gram-Positive Infections in Patients with Sepsis​. ​​International Journal of Molecular Sciences. ​2020;​21​(21):​​8318​. ​doi:10.3390/ijms21218318. 
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  • 2019 | Journal Article
    ​ ​Hosseini ASA, Uhlig J, Streit U, Uhlig A, Sprenger T, Wedi E, et al. ​Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy​. ​​European Radiology. ​2019;​29​(12):​​6653​-6661​. ​doi:10.1007/s00330-019-06284-8. 
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  • 2019 | Journal Article
    ​ ​Kauffels-Sprenger A, Lehmann W, Kutschka I, Trojan L, Ghadimi M. ​The Joy of Being a Surgeon - How to Generate Enthusiasm in Undergraduate Medical Education - A Local Example: The "Göttinger Aufschneidertag"​. ​​Zentralblatt für Chirurgie. ​2019;​144​(6):​​614​-615​. ​doi:10.1055/a-1007-2062. 
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  • 2019 | Journal Article
    ​ ​Petrova E, Lapshyn H, Bausch D, D'Haese J, Werner J, Klier T, et al. ​Risk stratification for postoperative pancreatic fistula using the pancreatic surgery registry StuDoQ​. ​​Pancreatology. ​2019;​19​(1):​​17​-25​. ​doi:10.1016/j.pan.2018.11.008. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Bolm L, Petrova E, Woehrmann L, Werner J, Uhl W, Nuessler N, et al. ​The impact of preoperative biliary stenting in pancreatic cancer: A case-matched study from the German nationwide pancreatic surgery registry (DGAV StuDoQ​. ​​Pancreatology. ​2019;​19​(7):​​985​-993​. ​doi:10.1016/j.pan.2019.09.007. 
    ​Details  DOI 
  • 2019 | Book Chapter
    ​ ​Nauck F. ​Palliative Chirurgie aus Sicht des Palliativmediziners​. ​In: Ghadimi MB, Homayounfar K, Kalff JC​, editors. ​Palliative Viszeralchirurgie. ​Berlin: ​Springer; ​2019. p. 13​-20​. ​
    ​Details 
  • 2019 | Journal Article
    ​ ​Uhl W, Ettrich TJ, Reinacher-Schick AC, Algül H, Friess H, Kornmann M, et al. ​NEONAX trial: Neoadjuvant plus adjuvant or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer, a phase II study of the AIO pancreatic cancer group (AIO-PAK-0313)—Safety interim analysis.​. ​​Journal of Clinical Oncology. ​2019;​37​(15_suppl):​​4128​-4128​. ​doi:10.1200/JCO.2019.37.15_suppl.4128. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Kosmala R, Fokas E, Flentje M, Sauer R, Liersch T, Graeven U, et al. ​OC-0384 QoL after multimodal treatment of rectal cancer with/without oxaliplatin (phase 3, CAO/ARO/AIO-04)​. ​​Radiotherapy and Oncology. ​2019;​133​:​​S191​-S192​. ​doi:10.1016/S0167-8140(19)30804-7. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Fokas E, Allgäuer M, Polat B, Klautke G, Grabenbauer G, Fietkau R, et al. ​OC-0501 Chemo-RT plus induction or consolidation chemotherapy for rectal cancer: a randomised phase 2 trial​. ​​Radiotherapy and Oncology. ​2019;​133​:​​S257​-S258​. ​doi:10.1016/S0167-8140(19)30921-1. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​König S, Ghadimi M. ​Kompetenzorientiertes Lehren in der Chirurgie​. ​​Zentralblatt für Chirurgie. ​2019;​144​(06):​​530​-531​. ​doi:10.1055/a-1028-0107. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Ettrich TJ, Berger AW, Schwerdel D, Reinacher-Schick AC, Uhl W, Alguel H, et al. ​A blood-based assay for diagnosis of early-stage pancreatic cancer.​. ​​Journal of Clinical Oncology. ​2019;​37​(4_suppl):​​234​-234​. ​doi:10.1200/JCO.2019.37.4_suppl.234. 
    ​Details  DOI 
  • 2019 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Ghadimi M. ​Editorial​. ​​Zentralblatt für Chirurgie. ​2019;​144​(02):​​137​-138​. ​doi:10.1055/a-0854-5748. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Kauffels A, Kitzmüller M, Gruber A, Nowack H, Bohnenberger H, Spitzner M, et al. ​Hepatic arterial infusion of irinotecan and EmboCept® S results in high tumor concentration of SN-38 in a rat model of colorectal liver metastases​. ​​Clinical & Experimental Metastasis. ​2019;​36​(1):​​57​-66​. ​doi:10.1007/s10585-019-09954-5. 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Diefenhardt M, Hofheinz R, Arnold D, Müller von den Grün J, Liersch T, Ströbel P, et al. ​OC-0499 Neutrophilia as prognostic factor for outcome in the CAO/ARO/AIO-04 phase 3 rectal cancer trial​. ​​Radiotherapy and Oncology. ​2019;​133​:​​S256​-S257​. ​doi:10.1016/S0167-8140(19)30919-3. 
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  • 2019 | Journal Article | 
    ​ ​Wittel UA, Lubgan D, Ghadimi M, Belyaev O, Uhl W, Bechstein WO, et al. ​Consensus in determining the resectability of locally progressed pancreatic ductal adenocarcinoma – results of the Conko-007 multicenter trial​. ​​BMC Cancer. ​2019;​19​(1). ​doi:10.1186/s12885-019-6148-5. 
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  • 2019 | Journal Article
    ​ ​Hosseini ASA, Uhlig J, Streit U, Voit D, Uhlig A, Ellenrieder V, et al. ​Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease​. ​​European Radiology. ​2019;​29​(9):​​4691​-4698​. ​doi:10.1007/s00330-019-06025-x. 
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  • 2019 | Journal Article | 
    ​ ​Runzheimer J, Mewes C, Büttner B, Hinz JM, Popov, Aron-Frederik, Ghadimi MB, et al. ​Lack of an Association between the Functional Polymorphism TREM-1 rs2234237 and the Clinical Course of Sepsis among Critically Ill Caucasian Patients-A Monocentric Prospective Genetic Association Study​. ​​Journal of Clinical Medicine. ​2019;​8​(3). ​doi:10.3390/jcm8030301. 
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  • 2019 | Journal Article | 
    ​ ​Mewes C, Büttner B, Hinz JM, Alpert A, Popov, Aron-Frederik, Ghadimi MB, et al. ​CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis​. ​​Journal of Clinical Medicine. ​2019;​8​(1). ​doi:10.3390/jcm8010070. 
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  • 2018 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Ghadimi M. ​Editorial​. ​​Zentralblatt für Chirurgie. ​2018;​143​(02):​​143​-144​. ​doi:10.1055/a-0545-0375. 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Zerche M, Sperling J, Ghadimi M. ​Spätfolgen nach onkologischer Chirurgie​. ​​Der Onkologe. ​2018;​24​(10):​​761​-771​. ​doi:10.1007/s00761-018-0403-2. 
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  • 2018 | Journal Article
    ​ ​Sprenger T, Beissbarth T, Sauer R, Fokas E, Hohenberger W, Liersch T, et al. ​The influence of hospital and surgeon volume on survival and local control in rectal cancer: Long-term results of the CAO/ARO/AIO-94 trial.​. ​​Journal of Clinical Oncology. ​2018;​36​(4, Suppl.):​​738​-738​. ​doi:10.1200/JCO.2018.36.4_suppl.738. 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Fokas E, Fietkau R, Hartmann A, Hohenberger W, Grützmann R, Ghadimi M, et al. ​Neoadjuvant rectal score as individual-level surrogate for disease-free survival in rectal cancer in the CAO/ARO/AIO-04 randomized phase III trial​. ​​Annals of Oncology. ​2018;​29​(7):​​1521​-1527​. ​doi:10.1093/annonc/mdy143. 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Hofheinz, R.-D., Arnold D, Fokas E, Kaufmann M, Hothorn T, Folprecht G, et al. ​Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial​. ​​Annals of Oncology. ​2018;​29​(8):​​1793​-1799​. ​doi:10.1093/annonc/mdy205. 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Fokas E, Fietkau R, Hartmann A, Hohenberger W, Grützmann R, Ghadimi M, et al. ​OC-0278: NAR score as surrogate for disease-free survival in the CAO/ARO/AIO-04 phase 3 rectal cancer trial​. ​​Radiotherapy and Oncology. ​2018;​127​:​​S142​. ​doi:10.1016/S0167-8140(18)30588-7. 
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  • 2018 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Ghadimi M. ​Editorial​. ​​Zentralblatt für Chirurgie. ​2018;​143​(04):​​351​-352​. ​doi:10.1055/a-0592-3284. 
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  • 2018 | Journal Article
    ​ ​Jo P, Kesruek H, Nietert M, Sahlmann C, Gaedcke J, Ghadimi M, et al. ​Inzidenz und prädiktive Faktoren des bilateralen papillären Schilddrüsenkarzinoms​. ​​Zentralblatt für Chirurgie. ​2018;​143​(04):​​361​-366​. ​doi:10.1055/a-0651-0878. 
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  • 2018 | Journal Article
    ​ ​von den Grün JM, Hartmann A, Fietkau R, Ghadimi M, Liersch T, Hohenberger W, et al. ​Can clinicopathological parameters predict for lymph node metastases in ypT0-2 rectal carcinoma? Results of the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 phase 3 trials​. ​​Radiotherapy and Oncology. ​2018;​128​(3):​​557​-563​. ​doi:10.1016/j.radonc.2018.06.008. 
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  • 2018 | Journal Article | 
    ​ ​Kristof K, Büttner B, Grimm A, Mewes C, Schmack B, Popov, Aron-Frederik, et al. ​Anaemia requiring red blood cell transfusion is associated with unfavourable 90-day survival in surgical patients with sepsis​. ​​BMC Research Notes. ​2018;​11​(1). ​doi:10.1186/s13104-018-3988-z. 
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  • 2018 | Journal Article | 
    ​ ​Schmidberger H, Ghadimi M. ​Langzeitfolgen onkologischer Behandlungen​. ​​Der Onkologe. ​2018;​24​(10):​​750​-753​. ​doi:10.1007/s00761-018-0459-z. 
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  • 2018 | Journal Article | 
    ​ ​Mewes C, Büttner B, Hinz JM, Alpert A, Popov, Aron-Frederik, Ghadimi MB, et al. ​The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis​. ​​Scientific Reports. ​2018;​8​(1). ​doi:10.1038/s41598-018-33246-9. 
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  • 2017 | Journal Article | 
    ​ ​Hinz JM, Büttner B, Kriesel F, Steinau M, Popov, Aron-Frederik, Ghadimi MB, et al. ​The FER rs4957796 TT genotype is associated with unfavorable 90-day survival in Caucasian patients with severe ARDS due to pneumonia.​. ​​Scientific reports. ​2017;​7​(1). ​doi:10.1038/s41598-017-08540-7. 
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  • 2017 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Ghadimi M. ​Editorial​. ​​Zentralblatt für Chirurgie. ​2017;​142​(02):​​159​-160​. ​doi:10.1055/s-0043-103319. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Fokas E, Ströbel P, Fietkau R, Ghadimi M, Liersch T, Grabenbauer G, et al. ​Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer​. ​​Journal of the National Cancer Institute. ​2017;​109​(12). ​doi:10.1093/jnci/djx095. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Sprenger T, Fietkau R, Raab, Hans-Rudolf, Hohenberger W, Liersch T, Rödel C, et al. ​The prognostic impact of surgical complications after combined modality treatment of rectal cancer: Long-term results of the CAO/ARO/AIO-94 trial​. ​​Journal of Clinical Oncology. ​2017;​35​(4, Suppl.):​​670​-670​. ​doi:10.1200/JCO.2017.35.4_suppl.670. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Bure I, Braun A, Kayser C, Geddert H, Schaefer I, Cameron S, et al. ​The expression of hematopoietic progenitor cell antigen CD34 is regulated by DNA methylation in a site‐dependent manner in gastrointestinal stromal tumours​. ​​International Journal of Cancer. ​2017;​141​(11):​​2296​-2304​. ​doi:10.1002/ijc.v141.11. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Sinn M, Bahra M, Liersch T, Gellert K, Messmann H, Bechstein W, et al. ​CONKO-005: Adjuvant Chemotherapy With Gemcitabine Plus Erlotinib Versus Gemcitabine Alone in Patients After R0 Resection of Pancreatic Cancer: A Multicenter Randomized Phase III Trial​. ​​Journal of Clinical Oncology. ​2017;​35​(29):​​3330​-3337​. ​doi:10.1200/JCO.2017.72.6463. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Neesse A, Grade M, Dango S, Ghadimi M, Ellenrieder V, Kunsch S, et al. ​A case report of delayed intra-abdominal and intra-luminal haemorrhage after polypectomy​. ​​Zeitschrift für Gastroenterologie. ​2017;​55​(10):​​1009​-1013​. ​doi:10.1055/s-0043-108125. 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Fokas E, Ghadimi M, Fietkau R, Ströbel P, Hartmann A, Sauer R, et al. ​PV-0325: Tumor Regression Grading in the CAO/ARO/AIO-04 phase 3 trial in locally advanced rectal carcinoma​. ​​Radiotherapy and Oncology. ​2017;​123​:​​S170​-S171​. ​doi:10.1016/S0167-8140(17)30767-3. 
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  • 2017 | Journal Article
    ​ ​Homayounfar K, König S, Rabe C, Beck-Broichsitter B, Lützen U, Ghadimi M, et al. ​Personalgewinnung und -entwicklung in viszeralchirurgischen Kliniken von Großkrankenhäusern – derzeitiger Stand und Möglichkeiten der Optimierung aus Industrie und Dienstleistungsgewerbe​. ​​Zentralblatt für Chirurgie. ​2017;​142​(06):​​566​-574​. ​doi:10.1055/s-0042-109562. 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper | 
    ​ ​Jo P, Azizian A, Salendo J, Kramer F, Bernhardt M, Wolff HA, et al. ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​. ​​International Journal of Molecular Sciences. ​2017;​18​(6). ​doi:10.3390/ijms18061140. 
    ​Details  DOI  WoS 
  • 2017 | Journal Article
    ​ ​Sahlmann, Carsten-Oliver, Homayounfar K, Niessner M, Dyczkowski J, Conradi, Lena-Christin, Braulke F, et al. ​Repeated Adjuvant Anti-CEA Radioimmunotherapy After Resection of Colorectal Liver Metastases: Safety, Feasibility, and Long-Term Efficacy Results of a Prospective Phase 2 Study​. ​​Cancer. ​2017;​123​(4):​​638​-649​. ​doi:10.1002/cncr.30390. 
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  • 2017 | Journal Article | 
    ​ ​Rühlmann F, Nietert MM, Sprenger T, Wolff HA, Homayounfar K, Middel P, et al. ​The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer​. ​​Journal of Cancer. ​2017;​8​(7):​​1229​-1237​. ​doi:10.7150/jca.16980. 
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  • 2017 | Journal Article | 
    ​ ​Lowes M, Kleiss M, Lueck R, Detken S, König AO, Nietert MM, et al. ​The utilization of multidisciplinary tumor boards (MDT) in clinical routine: results of a health care research study focusing on patients with metastasized colorectal cancer​. ​​International Journal of Colorectal Disease. ​2017;​32​(10):​​1463​-1469​. ​doi:10.1007/s00384-017-2871-z. 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Dango S, Beißbarth T, Weiss E, Hosseini ASA, Raddatz D, Ellenrieder V, et al. ​Relevance of surgery in patients with non-variceal upper gastrointestinal bleeding​. ​​Langenbeck s Archives of Surgery. ​2017;​402​(3):​​509​-519​. ​doi:10.1007/s00423-017-1552-2. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Conference Abstract
    ​ ​Sprenger T, Wirtz R, Pektas S, Bohnenberger H, Kauffels A, Conradi, Lena-Christin, et al. ​The prognostic role of the host immune response in rectal cancer patients treated with neoadjuvant chemoradiation.​. ​ Gastrointestinal Cancers Symposium; ​San Francisco, CA. -575​. ​doi:10.1200/jco.2016.34.4_suppl.575.
    ​Details  DOI  WoS 
  • 2016 | Journal Article
    ​ ​Schirmer M, Mergler C, Droege L, Guhlich M, Gaedcke J, Ghadimi M, et al. ​EP-2057: Radiotoxicity prediction by gene expression profiling when simulating therapy in matched fibroblasts​. ​​Radiotherapy and Oncology. ​2016;​119​:​​S970​-S971​. ​doi:10.1016/S0167-8140(16)33308-4. 
    ​Details  DOI 
  • 2016 | Conference Abstract
    ​ ​Homayounfar K, Sahlmann, Carsten-Oliver, Niessner M, Dyczkowski J, Conradi, Lena-Christin, Braulke F, et al. ​Repeated anti-CEA radioimmunotherapy (RIT) with 131I-Labetuzumab after complete resection of colorectal liver metastases - safety, feasibility and long-term efficacy results of a prospective phase-II-study​. ​​Oncology Research and Treatment. ​2016;​39​
    ​Details  WoS 
  • 2016 | Conference Abstract
    ​ ​Jo P, Gusky L, Nietert MM, Kitz J, Conradi, Lena-Christin, Müller-Dornieden A, et al. ​Neoadjuvant therapy in rectal cancer - challenges of biobanking tumor biopsies taken prior to treatment​. ​​Oncology Research and Treatment. ​2016;​39​
    ​Details  WoS 
  • 2016 | Journal Article
    ​ ​Sprenger T, Rothe H, Beißbarth T, Conradi, Lena-Christin, Kauffels A, Homayounfar K, et al. ​Lymph nodemetastases in ypT1/2 rectal cancer after neoadjuvant chemoradiotherapy. The Achilles heel of organ-preserving operative procedures?​. ​​Der Chirurg. ​2016;​87​(7):​​593​-601​. ​doi:10.1007/s00104-016-0170-9. 
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  • 2016 | Journal Article | 
    ​ ​Jo P, Nietert MM, Gusky L, Kitz J, Conradi, Lena-Christin, Müller-Dornieden A, et al. ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​. ​​Scientific Reports. ​2016;​6​. ​doi:10.1038/srep35589. 
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  • 2016 | Journal Article
    ​ ​Sprenger T, Rothe H, Conradi, Lena-Christin, Beissbarth T, Kauffels A, Kitz J, et al. ​Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup​. ​​Diseases of the Colon & Rectum. ​2016;​59​(5):​​377​-385​. ​doi:10.1097/DCR.0000000000000570. 
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  • 2015 | Journal Article
    ​ ​Styczen H, Nagelmeier I, Beißbarth T, Nietert MM, Homayounfar K, Sprenger T, et al. ​HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer​. ​​Oncotarget. ​2015;​6​(17):​​15065​-15076​. ​
    ​Details  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Haller F, Zhang J, Moskalev EA, Braun A, Otto C, Geddert H, et al. ​Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation of SPP1 as an independent prognostic factor​. ​​International Journal of Cancer. ​2015;​136​(5):​​1013​-1023​. ​doi:10.1002/ijc.29088. 
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  • 2015 | Journal Article | 
    ​ ​Mansur A, Klee Y, Popov, Aron-Frederik, Erlenwein J, Ghadimi MB, Beißbarth T, et al. ​Primary bacteraemia is associated with a higher mortality risk compared with pulmonary and intra-abdominal infections in patients with sepsis: a prospective observational cohort study​. ​​BMJ Open. ​2015;​5​(1). ​doi:10.1136/bmjopen-2014-006616. 
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  • 2015 | Journal Article | 
    ​ ​Mansur A, Liese B, Steinau M, Ghadimi MB, Bergmann I, Tzvetkov MV, et al. ​The CD14 rs2569190 TT Genotype Is Associated with an Improved 30-Day Survival in Patients with Sepsis: A Prospective Observational Cohort Study​. ​​PLoS ONE. ​2015;​10​(5). ​doi:10.1371/journal.pone.0127761. 
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  • 2015 | Journal Article
    ​ ​Zhang X, Schulz R, Edmunds S, Krueger E, Markert E, Gaedcke J, et al. ​MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP​. ​​Molecular Cell. ​2015;​59​(2):​​243​-257​. ​doi:10.1016/j.molcel.2015.05.036. 
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  • 2015 | Journal Article | 
    ​ ​Zhang S, Joseph AA, Gross L, Ghadimi MB, Frahm J, Beham AW. ​Diagnosis of Gastroesophageal Reflux Disease Using Real-time Magnetic Resonance Imaging​. ​​Scientific Reports. ​2015;​5​. ​doi:10.1038/srep12112. 
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  • 2015 | Journal Article | 
    ​ ​Mansur A, Mulwande E, Steinau M, Bergmann I, Popov, Aron-Frederik, Ghadimi MB, et al. ​Chronic kidney disease is associated with a higher 90-day mortality than other chronic medical conditions in patients with sepsis​. ​​Scientific Reports. ​2015;​5​. ​doi:10.1038/srep10539. 
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  • 2015 | Journal Article | 
    ​ ​Mansur A, Steinau M, Popov, Aron-Frederik, Ghadimi MB, Beißbarth T, Bauer M, et al. ​Impact of statin therapy on mortality in patients with sepsis-associated acute respiratory distress syndrome (ARDS) depends on ARDS severity: a prospective observational cohort study​. ​​BMC Medicine. ​2015;​13​. ​doi:10.1186/s12916-015-0368-6. 
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  • 2015 | Journal Article
    ​ ​Azizian A, Kramer F, Jo P, Wolff HA, Beißbarth T, Skarupke R, et al. ​Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer​. ​​World Journal of Surgery. ​2015;​39​(9):​​2329​-2335​. ​doi:10.1007/s00268-015-3083-8. 
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  • 2014 | Conference Abstract
    ​ ​Fokas E, Liersch T, Fietkau R, Hohenberger W, Beißbarth T, Hess C, et al. ​The prognostic role of tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: 11-year median follow-up results of the CAO/ARO/AIO-94 trial​. ​ 20th Annual Congress of the German-Society-for-Radiation-Oncology; ​Dusseldorf, GERMANY. ​Strahlentherapie und Onkologie. ​2014;​190​
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Quack H, Stanek K, Wolff HA, Dröge LH, Binder L, Bleckmann A, et al. ​Effects of 5-FU dose monitoring under neoadjuvant radiochemotherapy for locally advanced rectal cancer​. ​​Oncology Research and Treatment. ​2014;​37​
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Ruehlmann F, Nietert MM, Sprenger T, Wolff HA, Homayounfar K, Ghadimi MB, et al. ​SRC expression in locally advanced rectal cancer-before and after neoadjuvant chemoradiotherapy​. ​​Oncology Research and Treatment. ​2014;​37​
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Sprenger T, Rothe H, Conradi, Lena-Christin, Homayounfar K, Beißbarth T, Ghadimi MB, et al. ​Residual rectal cancer after preoperative radiochemotherapy (ypT1-2): An indication for local excision instead of radical surgery?​. ​ Gastrointestinal Cancers Symposium; ​San Francisco, CA. ​Journal of Clinical Oncology. ​2014;​32​(3)
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Spitzner M, Roesler B, Bielfeld C, Herzberg C, Emons G, Gaedcke J, et al. ​Targeting STAT3 in vitro and in vivo reveals a novel therapeutic strategy to sensitize colorectal cancer cells to chemoradiotherapy​. ​ 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR); ​San Diego, CA. ​Cancer Research. ​2014;​74​(19)doi:10.1158/1538-7445.AM2014-855.
    ​Details  DOI  WoS 
  • 2014 | Conference Abstract
    ​ ​Dröge LH, Hennies S, Beißbarth T, Lorenzen S, Conradi, Lena-Christin, Quack H, et al. ​Cytokinesis-block micronucleus cytome assay for in vivo and in vitro lymphocyte radiosensitivity in patients undergoing radiochemotherapy for locally advanced rectal cancer​. ​ 20th Annual Congress of the German-Society-for-Radiation-Oncology; ​Dusseldorf, GERMANY. ​Strahlentherapie und Onkologie. ​2014;​190​
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Grade M, Spitzner M, Roesler B, Bielfeld C, Gaedcke J, Wolff HA, et al. ​Targeting STAT3 as a therapeutic strategy to sensitize colorectal cancer to chemoradiotherapy​. ​​Oncology Research and Treatment. ​2014;​37​
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Emons G, Spitzner M, Reineke S, Möller J, Kendziorra E, Beißbarth T, et al. ​Wnt/beta-catenin signaling mediates resistance of colorectal cancer cells to chemoradiotherapy​. ​​San Diego, CA. ​Cancer Research. ​2014;​74​(19)doi:10.1158/1538-7445.AM2014-3946.
    ​Details  DOI  WoS 
  • 2014 | Conference Abstract
    ​ ​Beck J, Gaedcke J, Urnovitz HB, Bornemann-Kolatzki K, Grade M, Mitchell WM, et al. ​Comprehensive analyses of rectal cancer genomes to reveal copy number variations as potential predictor of induction therapy efficacy​. ​ 50th Annual Meeting of the American-Society-of-Clinical-Oncology; ​Chicago, IL. ​Journal of Clinical Oncology. ​2014;​32​(15)
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  • 2014 | Journal Article
    ​ ​Fokas E, Liersch T, Fietkau R, Hohenberger W, Beißbarth T, Hess CF, et al. ​Tumor Regression Grading After Preoperative Chemoradiotherapy for Locally Advanced Rectal Carcinoma Revisited: Updated Results of the CAO/ARO/AIO-94 Trial​. ​​Journal of Clinical Oncology. ​2014;​32​(15):​​1554​-1562​. ​doi:10.1200/JCO.2013.54.3769. 
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  • 2014 | Journal Article | 
    ​ ​Gaedcke J, Leha A, Claus R, Weichenhan D, Jung K, Kitz J, et al. ​Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer​. ​​Oncotarget. ​2014;​5​(18):​​8123​-8135​. ​doi:10.18632/oncotarget.2347. 
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  • 2014 | Journal Article | Research Paper | 
    ​ ​Ilgen P, Stoldt S, Conradi, Lena-Christin, Wurm CA, Rüschoff J, Ghadimi BM, et al. ​STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue​. ​​PLOS ONE. ​2014;​9​(7). ​doi:10.1371/journal.pone.0101563. 
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  • 2014 | Journal Article | 
    ​ ​Landmann H, Proia DA, He S, Ogden FL, Kramer, Franz-Josef, Beißbarth T, et al. ​UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib​. ​​Cell Death and Disease. ​2014;​5​. ​doi:10.1038/cddis.2014.378. 
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  • 2014 | Journal Article | 
    ​ ​Mansur A, von Gruben L, Popov, Aron-Frederik, Steinau M, Bergmann I, Ross D, et al. ​The regulatory toll-like receptor 4 genetic polymorphism rs11536889 is associated with renal, coagulation and hepatic organ failure in sepsis patients​. ​​Journal of Translational Medicine. ​2014;​12​. ​doi:10.1186/1479-5876-12-177. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Spitzner M, Roesler B, Bielfeld C, Emons G, Gaedcke J, Wolff HA, et al. ​STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo​. ​​International Journal of Cancer. ​2014;​134​(4):​​997​-1007​. ​doi:10.1002/ijc.28429. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Sprenger T, Rothe H, Becker H, Beißbarth T, Homayounfar K, Gauss K, et al. ​Lymph Node Metastases in Rectal Cancer After Preoperative Radiochemotherapy Impact of Intramesorectal Distribution and Residual Micrometastatic Involvement​. ​​American Journal of Surgical Pathology. ​2013;​37​(8):​​1283​-1289​. ​
    ​Details  PMID  PMC  WoS 
  • 2013 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Styczen H, Sprenger T, Wolff HA, Middel P, Nagelmeier I, et al. ​HER-2 and HER-3 expression in locally advanced rectal cancer and metachronous metastases: new targets for treatment approaches?​. ​​Onkologie. ​2013;​36​
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Quack H, Sprenger T, Wolff HA, Binder L, Ghadimi MB, et al. ​5-FU dose monitoring under neoadjuvant radiochemotherapy and adjuvant chemotherapy for locally advanced rectal cancer​. ​​Onkologie. ​2013;​36​
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Sprenger T, Gaedcke J, Conradi, Lena-Christin, Jo P, Jung K, Beißbarth T, et al. ​Association of CD133 expression levels with the k-ras mutation status in rectal cancers before and after preoperative radiochemotherapy​. ​ Gastrointestinal Cancers Symposium of the American-Society-of-Clinical-Oncology (ASCO); ​San Francisco, CA. ​Journal of Clinical Oncology. ​2013;​31​(4)
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  • 2013 | Journal Article
    ​ ​Sprenger T, Conradi, Lena-Christin, Beißbarth T, Ermert H, Homayounfar K, Middel P, et al. ​Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival​. ​​Cancer. ​2013;​119​(1):​​26​-35​. ​doi:10.1002/cncr.27703. 
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  • 2013 | Journal Article
    ​ ​Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, et al. ​Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/beta-Catenin Pathway in Colorectal Cancer​. ​​Cancer Research. ​2013;​73​(6):​​2003​-2013​. ​doi:10.1158/0008-5472.CAN-12-3159. 
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  • 2013 | Conference Paper
    ​ ​Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, et al. ​Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g​. ​ 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology; ​Ermatingen, SWITZERLAND. ​Radiotherapy and Oncology. ​2013;​108​(3):451​-457​. ​doi:10.1016/j.radonc.2013.06.032.
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  • 2013 | Journal Article
    ​ ​Conradi, Lena-Christin, Styczen H, Sprenger T, Wolff HA, Roedel C, Nietert MM, et al. ​Frequency of HER-2 Positivity in Rectal Cancer and Prognosis​. ​​American Journal of Surgical Pathology. ​2013;​37​(4):​​522​-531​. ​doi:10.1097/PAS.0b013e318272ff4d. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Fokas E, Conradi, Lena-Christin, Weiss C, Sprenger T, Middel P, Rau T, et al. ​Preoperative Chemoradiation Therapy With Capecitabine/Oxaliplatin and Cetuximab in Rectal Cancer: Long-Term Results of a Prospective Phase 1/2 Study​. ​​International Journal of Radiation Oncology*Biology*Physics. ​2013;​87​(5):​​992​-999​. ​doi:10.1016/j.ijrobp.2013.09.011. 
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  • 2012 | Conference Abstract
    ​ ​Sprenger T, Conradi, Lena-Christin, Beißbarth T, Homayounfar K, Rüschoff JR, Roedel C, et al. ​Clinical significance and prognostic impact of CD133 expression in rectal cancer treated with preoperative radiochemotherapy​. ​ 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO); ​Chicago, IL. ​Journal of Clinical Oncology. ​2012;​30​(15)
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Styczen H, Sprenger T, Wolff HA, Homayounfar K, Becker H, et al. ​HER-2 in locally advanced rectal cancer (cUICC II/III): positivity rate and prognostic value​. ​ 99th Annual Congress of the Swiss-Society-of-Surgery; ​Davos, SWITZERLAND. ​British Journal of Surgery. ​2012;​99​
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Styczen H, Sprenger T, Homayounfar K, Wolff HA, Bleckmann A, et al. ​HER2 status in locally advanced rectal cancer and metachronous metastases: Opportunity for a new therapeutic approach?​. ​​Chicago, IL. ​Journal of Clinical Oncology. ​2012;​30​(15)
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Spitzner M, Roesler B, Bielfeld C, Gaedcke J, Rave-Fränk M, Beißbarth T, et al. ​Stat3 is a potential molecular target for chemoradiosensitization of colorectal cancer cells​. ​​Cancer Research. ​2012;​72​doi:10.1158/1538-7445.AM2012-3446.
    ​Details  DOI  WoS 
  • 2012 | Conference Abstract
    ​ ​Grade M, Eimer C, Emons G, Kendziorra E, Spitzner M, Gaedcke J, et al. ​The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a beta-catenin independent manner​. ​​Cancer Research. ​2012;​72​doi:10.1158/1538-7445.AM2012-5729.
    ​Details  DOI  WoS 
  • 2012 | Journal Article
    ​ ​Gaedcke J, Grade M, Camps J, Sokilde R, Kaczkowski B, Schetter AJ, et al. ​The Rectal Cancer microRNAome - microRNA Expression in Rectal Cancer and Matched Normal Mucosa​. ​​Clinical Cancer Research. ​2012;​18​(18):​​4919​-4930​. ​doi:10.1158/1078-0432.CCR-12-0016. 
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  • 2012 | Journal Article
    ​ ​Schirmer MA, Mergler CPN, Rave-Fränk M, Herrmann MKA, Hennies S, Gaedcke J, et al. ​Acute Toxicity of Radiochemotherapy in Rectal Cancer Patients: A Risk Particularly for Carriers of the TGFB1 Pro25 variant​. ​​International Journal of Radiation Oncology*Biology*Physics. ​2012;​83​(1):​​149​-157​. ​doi:10.1016/j.ijrobp.2011.05.063. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Jo P, Jung K, Grade M, Conradi, Lena-Christin, Wolff HA, Kitz J, et al. ​CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer​. ​​Surgery. ​2012;​151​(4):​​564​-570​. ​doi:10.1016/j.surg.2011.08.013. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Gaedcke J, Emons G, et al. ​Silencing of TCF7L2 sensitizes Wnt/beta-catenin signaling-dependent colorectal cancer cells to radiation​. ​​Cancer Research. ​2011;​71​doi:10.1158/1538-7445.AM2011-2490.
    ​Details  DOI  WoS 
  • 2011 | Conference Abstract
    ​ ​Grade M, Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, et al. ​Identification of potential relevant pathways and genes for resistance to chemoradiotherapy in colorectal cancer cells​. ​​Cancer Research. ​2011;​71​doi:10.1158/1538-7445.AM2011-2508.
    ​Details  DOI  WoS 
  • 2011 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Bleckmann A, Sprenger T, Schirmer MA, Homayounfar K, Wolff HA, et al. ​Thymidylate Synthase as Biomarker in Rectal Cancer Patients After 5-FU-based Radiochemotherapy - Evaluation of the Prognostic Capacity in Pre-treatment Biopsies and Resected Adenocarcinoma​. ​ European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care; ​Stockholm, SWEDEN. ​European Journal of Cancer. ​2011;​47​
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Conradi, Lena-Christin, Bleckmann A, Schirmer MA, Sprenger T, Homayounfar K, Wolff HA, et al. ​Biomarker study in rectal cancer patients after 5FU-based radiochemotherapy: Evaluation of the prognostic capacity of thymidylate synthase in pretreatment biopsies and resected adenocarcinoma.​. ​​Journal of Clinical Oncology. ​2011;​29​(4)
    ​Details  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Sprenger T, Roedel F, Beißbarth T, Conradi, Lena-Christin, Homayounfar K, Ghadimi MB, et al. ​Association of survivin expression following neoadjuvant radiochemotherapy in rectal cancer with distant metastases and survival.​. ​​Journal of Clinical Oncology. ​2011;​29​(4)
    ​Details  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Sprenger T, Roedel F, Beißbarth T, Conradi, Lena-Christin, Yildirim M, Ghadimi MB, et al. ​Survivin Expression in Rectal Cancer During Preoperative Radiochemotherapy and Its Impact on Metastasis and Patients' Survival​. ​ European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care; ​Stockholm, SWEDEN. ​European Journal of Cancer. ​2011;​47​
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Christiansen H, Schirmer MA, Mergler CPN, Rave-Fränk M, Hennies S, Gaedcke J, et al. ​TGFB1 Pro25 allele as a risk marker for higher-grade acute Organ toxicity (CTC >= Grad2) during neoadjuvant Chemoradiotherapy in patients with locally advanced Rectal cancer (UICC Stage II/III)​. ​​Wiesbaden, GERMANY. ​Strahlentherapie und Onkologie. ​2011;​187​
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Roedel F, Sprenger T, Beißbarth T, Conradi, Lena-Christin, Rothe H, Homayonfaur K, et al. ​A lack of down-regulation of survivin after neoadjuvant Chemoradiotherapy for Rectal cancer with distant metastasis and Reduced survival rate linked​. ​ 17th Annual Meeting of the German-Society-for-Radiation-Oncology; ​Wiesbaden, GERMANY. ​Strahlentherapie und Onkologie. ​2011;​187​
    ​Details  WoS 
  • 2011 | Journal Article
    ​ ​Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Emons G, Gaedcke J, et al. ​Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy​. ​​Carcinogenesis. ​2011;​32​(12):​​1824​-1831​. ​doi:10.1093/carcin/bgr222. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Conradi, Lena-Christin, Bleckmann A, Schirmer MA, Sprenger T, Jo P, Homayounfar K, et al. ​Thymidylate Synthase as a Prognostic Biomarker for Locally Advanced Rectal Cancer after multimodal Treatment​. ​​Annals of Surgical Oncology. ​2011;​18​(9):​​2442​-2452​. ​doi:10.1245/s10434-011-1608-4. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, et al. ​A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets​. ​​International Journal of Cancer. ​2011;​128​(5):​​1069​-1079​. ​doi:10.1002/ijc.25453. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Sprenger T, Roedel F, Beißbarth T, Conradi, Lena-Christin, Rothe H, Homayounfar K, et al. ​Failure of Downregulation of Survivin Following Neoadjuvant Radiochemotherapy in Rectal Cancer Is Associated with Distant Metastases and Shortened Survival​. ​​Clinical Cancer Research. ​2011;​17​(6):​​1623​-1631​. ​doi:10.1158/1078-0432.CCR-10-2592. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Conference Abstract
    ​ ​Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, et al. ​A COMBINED FUNCTIONAL AND SYSTEMS BIOLOGY APPROACH IDENTIFIES COLORECTAL CANCER GENES AS NOVEL POTENTIAL THERAPEUTIC TARGETS​. ​ Congress of the International-Society-for-Cellular-Oncology; ​Dresden, GERMANY. ​Cellular Oncology. ​2010;​32​(3):164​-165​. ​
    ​Details  WoS 
  • 2010 | Conference Abstract
    ​ ​Gaedcke J, Grade M, Jung K, Camps J, Jo P, Becker H, et al. ​The effect of KRAS mutations on the rectal cancer transcriptome: clinical implications​. ​ 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics; ​Berlin, GERMANY. ​EJC SUPPLEMENTS. ​2010;​8​(7)doi:10.1016/S1359-6349(10)71892-9.
    ​Details  DOI  WoS 
  • 2010 | Conference Abstract
    ​ ​Kendziorra E, Spitzner M, Emons G, Ahlborn K, Gaedcke J, Rave-Fränk M, et al. ​RNAi-MEDIATED SILENCING OF TCF7L2 SENSITIZES COLORECTAL CANCER CELLS TO RADIATION​. ​ Congress of the International-Society-for-Cellular-Oncology; ​Dresden, GERMANY. ​Cellular Oncology. ​2010;​32​(3):229​-230​. ​
    ​Details  WoS 
  • 2010 | Journal Article
    ​ ​Gaedcke J, Grade M, Jung K, Camps J, Jo P, Emons G, et al. ​Mutated KRAS Results in Overexpression of DUSP4, a MAP-Kinase Phosphatase, and SMYD3, a Histone Methyltransferase, in Rectal Carcinomas​. ​​Genes Chromosomes and Cancer. ​2010;​49​(11):​​1024​-1034​. ​doi:10.1002/gcc.20811. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Gaedcke J, Grade M, Jung K, Schirmer MA, Jo P, Obermeyer C, et al. ​KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy​. ​​Radiotherapy and Oncology. ​2010;​94​(1):​​76​-81​. ​doi:10.1016/j.radonc.2009.10.001. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf, Jens-Gerd, et al. ​A GENE EXPRESSION SIGNATURE FOR CHEMORADIOSENSITIVITY OF COLORECTAL CANCER CELLS​. ​​International Journal of Radiation Oncology*Biology*Physics. ​2010;​78​(4):​​1184​-1192​. ​doi:10.1016/j.ijrobp.2010.06.023. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Opitz L, Salinas-Riester G, Grade M, Jung K, Jo P, Emons G, et al. ​Impact of RNA degradation on gene expression profiling​. ​​BMC Medical Genomics. ​2010;​3​. ​doi:10.1186/1755-8794-3-36. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Jung K, Grade M, Gaedcke J, Jo P, Opitz L, Becker H, et al. ​A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data​. ​​Computer Methods and Programs in Biomedicine. ​2010;​100​(2):​​132​-139​. ​doi:10.1016/j.cmpb.2010.03.016. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Sprenger T, Rothe H, Homayounfar K, Beißbarth T, Ghadimi MB, Becker H, et al. ​Preoperative Chemoradiotherapy Does Not Necessarily Reduce Lymph Node Retrieval in Rectal Cancer Specimens-Results from a Prospective Evaluation with Extensive Pathological Work-up​. ​​Journal of Gastrointestinal Surgery. ​2010;​14​(1):​​96​-103​. ​doi:10.1007/s11605-009-1057-6. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Conference Abstract
    ​ ​Gaedcke J, Grade M, Sokilde R, Kaczkowski B, Difilippantonio MJ, Ghadimi MB, et al. ​miRNA profiles predictive for response to chemoradiotherapy in rectal cancer​. ​​Cancer Research. ​2009;​69​
    ​Details  WoS 
  • 2009 | Conference Abstract
    ​ ​Kaune KM, Baumgart M, Gesk S, Middel P, Ghadimi MB, Siebert R, et al. ​Detection of a translocation t(8;22)(q24;q11) in specific skin lesions of extranodal MALT lymphoma displaying a vasculitis-/vasculopathy-like pattern​. ​​JDDG Journal der Deutschen Dermatologischen Gesellschaft. ​2009;​7​(9)
    ​Details  WoS 
  • 2007 | Journal Article
    ​ ​Lorf T, Homayounfar K, Liersch T, Niessner M, Schuetze G, Ghadimi MB, et al. ​Surgical therapy for colorectal liver metastases: Prospects and limits​. ​​VISZERALCHIRURGIE. ​2007;​42​(5):​​292​-299​. ​doi:10.1055/s-2007-981332. 
    ​Details  DOI  WoS 

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