Prof. Dr. med. Michael Ghadimi

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  • 2017 | Journal Article | Research Paper | 
    ​ ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​
    Jo, P. ; Azizian, A. ; Salendo, J. ; Kramer, F. ; Bernhardt, M. ; Wolff, H. A.   & Gruber, J. et al.​ (2017) 
    International Journal of Molecular Sciences, 18(6) art. 1140​.​ DOI: https://doi.org/10.3390/ijms18061140 
    ​Details  DOI  WoS 
  • 2017 | Journal Article | 
    ​ ​The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer​
    Rühlmann, F. ; Nietert, M. M. ; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Middel, P. & Bohnenberger, H.  et al.​ (2017) 
    Journal of Cancer, 8(7) pp. 1229​-1237​.​ DOI: https://doi.org/10.7150/jca.16980 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​
    Jo, P. ; Nietert, M. M. ; Gusky, L.; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016) 
    Scientific Reports, 6 art. 35589​.​ DOI: https://doi.org/10.1038/srep35589 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup​
    Sprenger, T. ; Rothe, H.; Conradi, L.-C. ; Beissbarth, T. ; Kauffels, A. ; Kitz, J.   & Homayounfar, K.  et al.​ (2016) 
    Diseases of the Colon & Rectum, 59(5) pp. 377​-385​.​ DOI: https://doi.org/10.1097/DCR.0000000000000570 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer​
    Styczen, H.; Nagelmeier, I.; Beißbarth, T. ; Nietert, M. M. ; Homayounfar, K. ; Sprenger, T.   & Boczek, U. et al.​ (2015) 
    Oncotarget, 6(17) pp. 15065​-15076​.​
    ​Details  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer​
    Azizian, A. ; Kramer, F. ; Jo, P. ; Wolff, H. A. ; Beißbarth, T. ; Skarupke, R. & Bernhardt, M.  et al.​ (2015) 
    World Journal of Surgery, 39(9) pp. 2329​-2335​.​ DOI: https://doi.org/10.1007/s00268-015-3083-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Conference Abstract
    ​ ​Effects of 5-FU dose monitoring under neoadjuvant radiochemotherapy for locally advanced rectal cancer​
    Quack, H.; Stanek, K.; Wolff, H. A. ; Dröge, L. H.; Binder, L.; Bleckmann, A.   & Nietert, M. M.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​SRC expression in locally advanced rectal cancer-before and after neoadjuvant chemoradiotherapy​
    Ruehlmann, F. ; Nietert, M. M. ; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Cytokinesis-block micronucleus cytome assay for in vivo and in vitro lymphocyte radiosensitivity in patients undergoing radiochemotherapy for locally advanced rectal cancer​
    Dröge, L. H.; Hennies, S.; Beißbarth, T. ; Lorenzen, S.; Conradi, L.-C. ; Quack, H. & Ghadimi, M. B.  et al.​ (2014)
    Strahlentherapie und Onkologie, 190 ​20th Annual Congress of the German-Society-for-Radiation-Oncology​, Dusseldorf, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Targeting STAT3 as a therapeutic strategy to sensitize colorectal cancer to chemoradiotherapy​
    Grade, M. ; Spitzner, M. ; Roesler, B.; Bielfeld, C.; Gaedcke, J. ; Wolff, H. A.   & Beißbarth, T.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Journal Article
    ​ ​STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Emons, G. ; Gaedcke, J. ; Wolff, H. A.   & Rave-Fränk, M.  et al.​ (2014) 
    International Journal of Cancer, 134(4) pp. 997​-1007​.​ DOI: https://doi.org/10.1002/ijc.28429 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Lymph Node Metastases in Rectal Cancer After Preoperative Radiochemotherapy Impact of Intramesorectal Distribution and Residual Micrometastatic Involvement​
    Sprenger, T. ; Rothe, H.; Becker, H.; Beißbarth, T. ; Homayounfar, K. ; Gauss, K. & Kitz, J.  et al.​ (2013) 
    American Journal of Surgical Pathology, 37(8) pp. 1283​-1289​.​
    ​Details  PMID  PMC  WoS 
  • 2013 | Conference Abstract
    ​ ​HER-2 and HER-3 expression in locally advanced rectal cancer and metachronous metastases: new targets for treatment approaches?​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Middel, P.; Nagelmeier, I. & Rüschoff, J. R.  et al.​ (2013)
    Onkologie, 36 
    Basel​: Karger.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​5-FU dose monitoring under neoadjuvant radiochemotherapy and adjuvant chemotherapy for locally advanced rectal cancer​
    Conradi, L.-C. ; Quack, H.; Sprenger, T. ; Wolff, H. A. ; Binder, L.; Ghadimi, M. B.   & Homayounfar, K.  et al.​ (2013)
    Onkologie, 36 
    Basel​: Karger.
    ​Details  WoS 
  • 2013 | Journal Article
    ​ ​Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival​
    Sprenger, T. ; Conradi, L.-C. ; Beißbarth, T. ; Ermert, H.; Homayounfar, K. ; Middel, P. & Rüschoff, J. R.  et al.​ (2013) 
    Cancer, 119(1) pp. 26​-35​.​ DOI: https://doi.org/10.1002/cncr.27703 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Conference Paper
    ​ ​Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g​
    Salendo, J. ; Spitzner, M. ; Kramer, F. ; Zhang, X.; Jo, P. ; Wolff, H. A.   & Kitz, J.  et al.​ (2013)
    Radiotherapy and Oncology, 108(3) pp. 451​-457. ​13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology​, Ermatingen, SWITZERLAND.
    Clare​: Elsevier Ireland Ltd. DOI: https://doi.org/10.1016/j.radonc.2013.06.032 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Frequency of HER-2 Positivity in Rectal Cancer and Prognosis​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Roedel, C.; Nietert, M. M.   & Homayounfar, K.  et al.​ (2013) 
    American Journal of Surgical Pathology, 37(4) pp. 522​-531​.​ DOI: https://doi.org/10.1097/PAS.0b013e318272ff4d 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Conference Abstract
    ​ ​HER-2 in locally advanced rectal cancer (cUICC II/III): positivity rate and prognostic value​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Becker, H. & Ghadimi, M. B.  et al.​ (2012)
    British Journal of Surgery, 99 ​99th Annual Congress of the Swiss-Society-of-Surgery​, Davos, SWITZERLAND.
    Malden​: Wiley-blackwell.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​HER2 status in locally advanced rectal cancer and metachronous metastases: Opportunity for a new therapeutic approach?​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Homayounfar, K. ; Wolff, H. A. ; Bleckmann, A.   & Rüschoff, J. R.  et al.​ (2012)
    Journal of Clinical Oncology, 30(15) , Chicago, IL.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a beta-catenin independent manner​
    Grade, M. ; Eimer, C. ; Emons, G. ; Kendziorra, E.; Spitzner, M. ; Gaedcke, J.   & Wolff, H. A.  et al.​ (2012)
    Cancer Research, 72 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2012-5729 
    ​Details  DOI  WoS 
  • 2012 | Journal Article
    ​ ​Acute Toxicity of Radiochemotherapy in Rectal Cancer Patients: A Risk Particularly for Carriers of the TGFB1 Pro25 variant​
    Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Herrmann, M. K. A.; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2012) 
    International Journal of Radiation Oncology*Biology*Physics, 83(1) pp. 149​-157​.​ DOI: https://doi.org/10.1016/j.ijrobp.2011.05.063 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer​
    Jo, P. ; Jung, K. ; Grade, M. ; Conradi, L.-C. ; Wolff, H. A. ; Kitz, J.   & Becker, H. et al.​ (2012) 
    Surgery, 151(4) pp. 564​-570​.​ DOI: https://doi.org/10.1016/j.surg.2011.08.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Thymidylate Synthase as Biomarker in Rectal Cancer Patients After 5-FU-based Radiochemotherapy - Evaluation of the Prognostic Capacity in Pre-treatment Biopsies and Resected Adenocarcinoma​
    Conradi, L.-C. ; Bleckmann, A. ; Sprenger, T. ; Schirmer, M. A. ; Homayounfar, K. ; Wolff, H. A.   & Becker, H. et al.​ (2011)
    European Journal of Cancer, 47 ​European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care​, Stockholm, SWEDEN.
    Oxford​: Elsevier Sci Ltd.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Biomarker study in rectal cancer patients after 5FU-based radiochemotherapy: Evaluation of the prognostic capacity of thymidylate synthase in pretreatment biopsies and resected adenocarcinoma.​
    Conradi, L.-C. ; Bleckmann, A. ; Schirmer, M. A. ; Sprenger, T. ; Homayounfar, K. ; Wolff, H. A.   & Becker, H. et al.​ (2011)
    Journal of Clinical Oncology, 29(4) 
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​TGFB1 Pro25 allele as a risk marker for higher-grade acute Organ toxicity (CTC >= Grad2) during neoadjuvant Chemoradiotherapy in patients with locally advanced Rectal cancer (UICC Stage II/III)​
    Christiansen, H.; Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2011)
    Strahlentherapie und Onkologie, 187 , Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​A lack of down-regulation of survivin after neoadjuvant Chemoradiotherapy for Rectal cancer with distant metastasis and Reduced survival rate linked​
    Roedel, F.; Sprenger, T. ; Beißbarth, T. ; Conradi, L.-C. ; Rothe, H.; Homayonfaur, K. & Wolff, H. A.  et al.​ (2011)
    Strahlentherapie und Onkologie, 187 ​17th Annual Meeting of the German-Society-for-Radiation-Oncology​, Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2011 | Journal Article
    ​ ​Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy​
    Kendziorra, E.; Ahlborn, K.; Spitzner, M. ; Rave-Fränk, M. ; Emons, G. ; Gaedcke, J.   & Kramer, F.  et al.​ (2011) 
    Carcinogenesis, 32(12) pp. 1824​-1831​.​ DOI: https://doi.org/10.1093/carcin/bgr222 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Thymidylate Synthase as a Prognostic Biomarker for Locally Advanced Rectal Cancer after multimodal Treatment​
    Conradi, L.-C. ; Bleckmann, A. ; Schirmer, M. A. ; Sprenger, T. ; Jo, P. ; Homayounfar, K.   & Wolff, H. A.  et al.​ (2011) 
    Annals of Surgical Oncology, 18(9) pp. 2442​-2452​.​ DOI: https://doi.org/10.1245/s10434-011-1608-4 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Failure of Downregulation of Survivin Following Neoadjuvant Radiochemotherapy in Rectal Cancer Is Associated with Distant Metastases and Shortened Survival​
    Sprenger, T. ; Roedel, F.; Beißbarth, T. ; Conradi, L.-C. ; Rothe, H.; Homayounfar, K.   & Wolff, H. A.  et al.​ (2011) 
    Clinical Cancer Research, 17(6) pp. 1623​-1631​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-10-2592 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Schirmer, M. A. ; Jo, P. ; Obermeyer, C. & Wolff, H. A.  et al.​ (2010) 
    Radiotherapy and Oncology, 94(1) pp. 76​-81​.​ DOI: https://doi.org/10.1016/j.radonc.2009.10.001 
    ​Details  DOI  PMID  PMC  WoS 

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