Dr. rer. nat. Robyn Laura Kosinsky

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Cell Type-Specific Induction of Inflammation-Associated Genes in Crohn’s Disease and Colorectal Cancer​
    Saul, D. ; Leite Barros, L.; Wixom, A. Q.; Gellhaus, B.; Gibbons, H. R.; Faubion, W. A. & Kosinsky, R. L. ​ (2022) 
    International Journal of Molecular Sciences, 23(6) pp. 3082​.​ DOI: https://doi.org/10.3390/ijms23063082 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues​
    Saul, D. ; Kosinsky, R. L. ; Atkinson, E. J.; Doolittle, M. L.; Zhang, X.; LeBrasseur, N. K. & Pignolo, R. J. et al.​ (2022) 
    Nature Communications, 13(1).​ DOI: https://doi.org/10.1038/s41467-022-32552-1 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Epigenetics of Aging and Aging-Associated Diseases​
    Saul, D.   & Kosinsky, R. L. ​ (2021) 
    International Journal of Molecular Sciences, 22(1) pp. 401​.​ DOI: https://doi.org/10.3390/ijms22010401 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk​
    Najafova, Z. ; Liu, P.; Wegwitz, F. ; Ahmad, M.; Tamon, L.; Kosinsky, R. L.   & Xie, W.  et al.​ (2020) 
    Cell Death and Differentiation, 28(2) pp. 700​-714​.​ DOI: https://doi.org/10.1038/s41418-020-00614-w 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis​
    Wegwitz, F. ; Prokakis, E.; Pejkovska, A.; Kosinsky, R. L. ; Glatzel, M.; Pantel, K. & Wikman, H. et al.​ (2020) 
    Cell Death & Disease, 11(10).​ DOI: https://doi.org/10.1038/s41419-020-03081-w 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer​
    Kosinsky, R. L. ; Helms, M.; Zerche, M.; Wohn, L.; Dyas, A.; Prokakis, E. & Kazerouni, Z. B. et al.​ (2019) 
    Cell Death & Disease, 10(12).​ DOI: https://doi.org/10.1038/s41419-019-2141-9 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells​
    Sen, M. ; Wang, X.; Hamdan, F. H. ; Rapp, J.; Eggert, J.; Kosinsky, R. L.   & Wegwitz, F.  et al.​ (2019) 
    Clinical Epigenetics, 11(1).​ DOI: https://doi.org/10.1186/s13148-019-0690-5 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Dextran Sodium Sulfate-induced Colitis as a Model for Sarcopenia in Mice​
    Saul, D.   & Kosinsky, R. L. ​ (2019) 
    Inflammatory Bowel Diseases, 26(1) art. izz127​.​ DOI: https://doi.org/10.1093/ibd/izz127 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Loss of RNF40 Decreases NF-B Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice​
    Kosinsky, R. L. ; Chua, R. L.; Qui, M.; Saul, D. ; Mehlich, D.; Ströbel, P.   & Schildhaus, H.-U.  et al.​ (2019) 
    Journal of Crohn's and Colitis, 13(3) pp. 362​-373​.​ DOI: https://doi.org/10.1093/ecco-jcc/jjy165 
    ​Details  DOI  PMID  PMC  WoS 
  • 2019 | Journal Article
    ​ ​Effect of the Lipoxygenase Inhibitor Baicalein on Bone Tissue and Bone Healing in Ovariectomized Rats​
    Saul, D. ; Weber, M.; Zimmermann, M. H.; Kosinsky, R. L. ; Hoffmann, D. B. ; Menger, B.   & Taudien, S. et al.​ (2019) 
    Nutrition & Metabolism, 16(1) art. 4​.​ DOI: https://doi.org/10.1186/s12986-018-0327-2 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity​
    Kosinsky, R. L. ; Zerche, M.; Saul, D. ; Wohn, L.; Wegwitz, F. ; Begus-Nahrmann, Y. & Johnsen, S. A. ​ (2019) 
    Cell Death and Differentiation, 27(4) pp. 1328​-1340​.​ DOI: https://doi.org/10.1038/s41418-019-0420-8 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Intestinal Inflammation and Tumor Burden as Determinants for Bone Fragility in APC-Driven Tumorigenesis​
    Saul, D. ; Schilling, A. F.   & Kosinsky, R. L. ​ (2018) 
    Inflammatory Bowel Diseases, 24(11) pp. 2386​-2393​.​ DOI: https://doi.org/10.1093/ibd/izy234 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper
    ​ ​Effect of Strontium Ranelate on the Muscle and Vertebrae of Ovariectomized Rats​
    Saul, D. ; Harlas, B.; Ahrabi, A.; Kosinsky, R. L. ; Hoffmann, D. B. ; Wassmann, M.   & Wigger, R. et al.​ (2017) 
    Calcified Tissue International, 102(6) pp. 705​-719​.​ DOI: https://doi.org/10.1007/s00223-017-0374-0 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Effect of the lipoxygenase-inhibitors baicalein and zileuton on the vertebra in ovariectomized rats​
    Saul, D. ; Gleitz, S. ; Nguyen, H. H.; Kosinsky, R. L. ; Sehmisch, S. ; Hoffmann, D. B.   & Wassmann, M.  et al.​ (2017) 
    Bone, 101 pp. 134​-144​.​ DOI: https://doi.org/10.1016/j.bone.2017.04.011 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats​
    Saul, D. ; Kling, J. H.; Kosinsky, R. L. ; Hoffmann, D. B. ; Komrakova, M. ; Wick, M. & Menger, B.  et al.​ (2016) 
    Journal of Nutrition and Metabolism, 2016 pp. 1​-14​.​ DOI: https://doi.org/10.1155/2016/3703216 
    ​Details  DOI  PMID  PMC 

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