Safety relevant knowledge of orally anticoagulated patients without self-monitoring: a baseline survey in primary care

2014 | journal article; research paper. A publication with affiliation to the University of Göttingen.

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​Chenot, Jean-Franois, Thanh Duc Hua, T. D. H., Abu Abed, M., Schneider-Rudt, H., Friede, T., Schneider, S. & Vormfelde, S. V. (2014). ​Safety relevant knowledge of orally anticoagulated patients without self-monitoring: a baseline survey in primary care. BMC Family Practice15, Article 104​. ​doi: 


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Chenot, Jean-Franois; Thanh Duc Hua, Thanh Duc Hua; Abu Abed, Manar; Schneider-Rudt, Hannelore; Friede, Tim ; Schneider, Simon; Vormfelde, Stefan Viktor
Background: Effective and safe management of oral anticoagulant treatment (OAT) requires a high level of patient knowledge and adherence. The aim of this study was to assess patient knowledge about OAT and factors associated with patient knowledge. Methods: This is a baseline survey of a cluster-randomized controlled trial in 22 general practices with an educational intervention for patients or their caregivers. We assessed knowledge about general information on OAT and key facts regarding nutrition, drug-interactions and other safety precautions of 345 patients at baseline. Results: Participants rated their knowledge about OAT as excellent to good (56%), moderate (36%) or poor (8%). However, there was a discrepancy between self-rated knowledge and evaluated actual knowledge and we observed serious knowledge gaps. Half of the participants (49%) were unaware of dietary recommendations. The majority (80%) did not know which non-prescription analgesic is the safest and 73% indicated they would not inform pharmacists about OAT. Many participants (35-75%) would not recognize important emergency situations. After adjustment in a multivariate analysis, older age and less than 10 years education remained significantly associated with lower overall score, but not with self-rated knowledge. Conclusions: Patients have relevant knowledge gaps, potentially affecting safe and effective OAT. There is a need to assess patient knowledge and for structured education programs.
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BMC Family Practice 
Institut für Allgemeinmedizin 



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