Prof. Dr. med. Jens Wiltfang

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  • 2022 | Journal Article
    ​ ​Kosten der Diagnostik kognitiver Störungen in deutschen Gedächtnisambulanzen​
    Onur, O. A.; Wolff-Menzler, C. ; Arnim, C. A. F. von ; Jessen, F.; Fink, G. R.; Wiltfang, J.   & Laske, C. et al.​ (2022) 
    Fortschritte der Neurologie · Psychiatrie, 90(07/08) pp. 361​-367​.​ DOI: https://doi.org/10.1055/a-1871-9889 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults​
    Böttcher, A.; Zarucha, A.; Köbe, T.; Gaubert, M.; Höppner, A.; Altenstein, S. & Bartels, C.  et al.​ (2022) 
    Frontiers in Psychology, 13 art. 945709​.​ DOI: https://doi.org/10.3389/fpsyg.2022.945709 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer’s disease spectrum​
    Amaefule, C. O.; Dyrba, M.; Wolfsgruber, S.; Polcher, A.; Schneider, A. ; Fliessbach, K. & Spottke, A. et al.​ (2021) 
    NeuroImage: Clinical, 29 pp. 102533​.​ DOI: https://doi.org/10.1016/j.nicl.2020.102533 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer’s Disease Dementia via Lead-Lag Analysis​
    Fuentes, M.; Klostermann, A.; Kleineidam, L.; Bauer, C.; Schuchhardt, J.; Maier, W. & Jessen, F. et al.​ (2020) 
    Journal of Alzheimer's Disease, 76(3) pp. 1005​-1015​.​ DOI: https://doi.org/10.3233/JAD-200230 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Bupropion for the Treatment of Apathy in Alzheimer Disease​
    Maier, F.; Spottke, A.; Bach, J.-P.; Bartels, C. ; Buerger, K.; Dodel, R. & Fellgiebel, A. et al.​ (2020) 
    JAMA Network Open, 3(5) pp. e206027​.​ DOI: https://doi.org/10.1001/jamanetworkopen.2020.6027 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer’s disease spectrum​
    Herdick, M.; Dyrba, M.; Fritz, H. Fritz, Hans-Christian J.; Altenstein, S.; Ballarini, T.; Brosseron, F. & Buerger, K. et al.​ (2020) 
    NeuroImage: Clinical, 28 pp. 102495​.​ DOI: https://doi.org/10.1016/j.nicl.2020.102495 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Minor neuropsychological deficits in patients with subjective cognitive decline​
    Wolfsgruber, S.; Kleineidam, L.; Guski, J.; Polcher, A.; Frommann, I.; Roeske, S. & Spruth, E. J. et al.​ (2020) 
    Neurology, 95(9) pp. e1134​-e1143​.​ DOI: https://doi.org/10.1212/WNL.0000000000010142 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly​
    Rhein, C.; Mühle, C.; Lenz, B.; Richter-Schmidinger, T.; Kogias, G.; Boix, F. & Lourdusamy, A. et al.​ (2020) 
    Brain Research Bulletin, 161 pp. 13​-20​.​ DOI: https://doi.org/10.1016/j.brainresbull.2020.05.001 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment​
    Kleineidam, L.; Chouraki, V.; Próchnicki, T.; van der Lee, S. J.; Madrid-Márquez, L.; Wagner-Thelen, H. & Karaca, I. et al.​ (2020) 
    Acta Neuropathologica, 139(6) pp. 1025​-1044​.​ DOI: https://doi.org/10.1007/s00401-020-02138-6 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers—results from the DELCODE study​
    Sannemann, L.; Schild, A.-K.; Altenstein, S.; Bartels, C. ; Brosseron, F.; Buerger, K. & Cosma, N. C. et al.​ (2020) 
    Alzheimer's Research & Therapy, 12(1).​ DOI: https://doi.org/10.1186/s13195-020-00701-7 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer’s disease based on multicenter diffusion tensor imaging​
    Brueggen, K.; Dyrba, M.; Cardenas-Blanco, A.; Schneider, A. ; Fliessbach, K.; Buerger, K. & Janowitz, D. et al.​ (2019) 
    Journal of Neurology, 266(10) pp. 2465​-2474​.​ DOI: https://doi.org/10.1007/s00415-019-09429-3 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer’s Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness​
    Teipel, S. J.; Kuper-Smith, J. O.; Bartels, C. ; Brosseron, F.; Buchmann, M.; Buerger, K. & Catak, C. et al.​ (2019) 
    Journal of Alzheimer's Disease, 72(2) pp. 455​-465​.​ DOI: https://doi.org/10.3233/JAD-190446 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study​
    Miebach, L.; Wolfsgruber, S.; Polcher, A.; Peters, O.; Menne, F.; Luther, K. & Incesoy, E. et al.​ (2019) 
    Alzheimer's Research & Therapy, 11(1).​ DOI: https://doi.org/10.1186/s13195-019-0515-y 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​
    Lewczuk, P. ; Riederer, P.; O’Bryant, S. E.; Verbeek, M. M.; Dubois, B.; Visser, P. J. & Jellinger, K. A. et al.​ (2018) 
    The World Journal of Biological Psychiatry, 19(4) pp. 244​-328​.​ DOI: https://doi.org/10.1080/15622975.2017.1375556 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes​
    Espinosa, A.; Hernández-Olasagarre, B.; Moreno-Grau, S.; Kleineidam, L.; Heilmann-Heimbach, S.; Hernández, I. & Wolfsgruber, S. et al.​ (2018) 
    Frontiers in Aging Neuroscience, 10.​ DOI: https://doi.org/10.3389/fnagi.2018.00340 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease​
    Franzmeier, N.; Düzel, E.; Jessen, F.; Buerger, K.; Levin, J.; Duering, M. & Dichgans, M. et al.​ (2018) 
    Brain: A Journal of Neurology, 141(4) pp. 1186​-1200​.​ DOI: https://doi.org/10.1093/brain/awy008 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)​
    Jessen, F.; Spottke, A.; Boecker, H.; Brosseron, F.; Buerger, K.; Catak, C. & Fliessbach, K. et al.​ (2018) 
    Alzheimer's Research & Therapy, 10(1).​ DOI: https://doi.org/10.1186/s13195-017-0314-2 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia​
    Frölich, L.; Peters, O.; Lewczuk, P. ; Gruber, O. ; Teipel, S. J.; Gertz, H. J. & Jahn, H. et al.​ (2017) 
    Alzheimer's Research & Therapy, 9(1) art. 84​.​ DOI: https://doi.org/10.1186/s13195-017-0301-7 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment​
    Wolfsgruber, S.; Polcher, A.; Koppara, A.; Kleineidam, L.; Frölich, L.; Peters, O. & Hüll, M. et al.​ (2017) 
    Journal of Alzheimer's Disease, 58(3) pp. 939​-950​.​ DOI: https://doi.org/10.3233/JAD-161252 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment​
    Bey, K.; Wolfsgruber, S.; Karaca, I.; Wagner, H.; Lardenoije, R.; Becker, J. & Milz, E. et al.​ (2016) 
    Epigenomics, 8(5) pp. 593​-598​.​ DOI: https://doi.org/10.2217/epi-2015-0014 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment​
    Koppara, A.; Wolfsgruber, S.; Kleineidam, L.; Schmidtke, K.; Frölich, L.; Kurz, A. & Schulz, S. et al.​ (2016) 
    Journal of Alzheimer's Disease, 49(2) pp. 547​-560​.​ DOI: https://doi.org/10.3233/jad-150257 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment​
    Louwersheimer, E.; Wolfsgruber, S.; Espinosa, A.; Lacour, A.; Heilmann-Heimbach, S.; Alegret, M. & Hernández, I. et al.​ (2016) 
    Alzheimer's & Dementia, 12(8) pp. 872​-881​.​ DOI: https://doi.org/10.1016/j.jalz.2016.01.006 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Leitliniengerechte stationäre psychiatrisch-psychotherapeutische Behandlung psychischer und Verhaltenssymptome bei Demenz​
    Radenbach, K. ; Retzlik, J.; Meyer-Rötz, S. H. ; Wolff-Menzler, C. ; Wolff, J.; Esselmann, H.   & Godemann, F. et al.​ (2016) 
    Der Nervenarzt,.​ DOI: https://doi.org/10.1007/s00115-016-0195-9 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI​
    Wolfsgruber, S.; Jessen, F.; Koppara, A.; Kleineidam, L.; Schmidtke, K.; Frölich, L. & Kurz, A. et al.​ (2015) 
    Neurology, 84(12) pp. 1261​-1268​.​ DOI: https://doi.org/10.1212/wnl.0000000000001399 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​PLD3 in non-familial Alzheimer's disease​
    Heilmann, S.; Drichel, D.; Clarimon, J.; Fernández, V.; Lacour, A.; Wagner, H. & Thelen, M. et al.​ (2015) 
    Nature, 520(7545) pp. E3​-E5​.​ DOI: https://doi.org/10.1038/nature14039 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study​
    Morgen, K.; Schneider, M.; Frölich, L.; Tost, H.; Plichta, M. M.; Kölsch, H. & Rakebrandt, F.  et al.​ (2015) 
    Alzheimer's Research & Therapy, 7(1).​ DOI: https://doi.org/10.1186/s13195-015-0111-8 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type​
    Popp, J.; Wolfsgruber, S.; Heuser, I.; Peters, O.; Hüll, M.; Schröder, J. & Möller, H.-J. et al.​ (2015) 
    Neurobiology of Aging, 36(2) pp. 601​-607​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2014.10.031 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article
    ​ ​The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease​
    Louwersheimer, E.; Ramirez, A.; Cruchaga, C.; Becker, T.; Kornhuber, J. ; Peters, O. & Heilmann, S. et al.​ (2014) 
    Neurobiology of Aging, 36(3) pp. 1605.e13​-1605.e20​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2014.12.007 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease​
    Ramirez, A.; van der Flier, W. M.; Herold, C.; Ramonet, D.; Heilmann, S.; Lewczuk, P.   & Popp, J. et al.​ (2014) 
    Human Molecular Genetics, 23(24) pp. 6644​-6658​.​ DOI: https://doi.org/10.1093/hmg/ddu372 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​PLASMA HOMOCYSTEINE AND CEREBROSPINAL FLUID NEURODEGENERATION BIOMARKERS IN MILD COGNITIVE IMPAIRMENT AND DEMENTIA​
    Alexopoulos, P.; Günther, F.; Popp, J.; Jessen, F.; Peters, O.; Wolf, S. & Kneib, T.  et al.​ (2009) 
    Journal of the American Geriatrics Society, 57(4) pp. 737​-739​.​ DOI: https://doi.org/10.1111/j.1532-5415.2009.02212.x 
    ​Details  DOI 

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