Prof. Dr. Henning Urlaub

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  • 2020 | Journal Article
    ​ ​Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome​
    Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D. E.; Will, C. L.; Hartmuth, K. & Urlaub, H.  et al.​ (2020) 
    Molecular Cell, 80(1) pp. 127​-139.e6​.​ DOI: https://doi.org/10.1016/j.molcel.2020.09.012 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Molecular architecture of the human 17S U2 snRNP​
    Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E. & Hofele, R. et al.​ (2020) 
    Nature, 583(7815) pp. 310​-313​.​ DOI: https://doi.org/10.1038/s41586-020-2344-3 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex​
    Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O. & Urlaub, H.  et al.​ (2018) 
    Cell, 172(3) pp. 454​-464.e11​.​ DOI: https://doi.org/10.1016/j.cell.2018.01.010 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Protein-Cross-Linking zur Aufklärung von komplexen Strukturen​
    Dybkov, O.; Stützer, A.; Bertram, K.; Kastner, B.; Stark, H. ; Lührmann, R.   & Urlaub, H. ​ (2018) 
    BIOspektrum, 24(3) pp. 278​-282​.​ DOI: https://doi.org/10.1007/s12268-018-0909-6 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation​
    Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L. & Urlaub, H.  et al.​ (2017) 
    Cell, 170(4) pp. 701​-713.e11​.​ DOI: https://doi.org/10.1016/j.cell.2017.07.011 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Cryo-EM structure of a human spliceosome activated for step 2 of splicing​
    Bertram, K.; Agafonov, D. E.; Liu, W.-T.; Dybkov, O.; Will, C. L.; Hartmuth, K. & Urlaub, H.  et al.​ (2017) 
    Nature, 542(7641) pp. 318​.​ DOI: https://doi.org/10.1038/nature21079 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Molecular architecture of the human U4/U6.U5 tri-snRNP​
    Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.-T.; Urlaub, H.   & Lührmann, R.  et al.​ (2016) 
    Science, 351(6280) pp. 1416​-1420​.​ DOI: https://doi.org/10.1126/science.aad2085 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Molecular architecture of the Saccharomyces cerevisiae activated spliceosome​
    Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A. & Kumar, V. et al.​ (2016) 
    Science, 353(6306) pp. 1399​-1405​.​ DOI: https://doi.org/10.1126/science.aag1906 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper | 
    ​ ​A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity​
    Boesler, C.; Rigo, N.; Anokhina, M. M.; Tauchert, M. J. ; Agafonov, D. E.; Kastner, B. & Urlaub, H.  et al.​ (2016) 
    Nature Communications, 7 art. 11997​.​ DOI: https://doi.org/10.1038/ncomms11997 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | Research Paper | 
    ​ ​Mapping the binding site of snurportin 1 on native U1 snRNP by cross-linking and mass spectrometry​
    Kuehn-Hoelsken, E.; Lenz, C. ; Dickmanns, A. ; Hsiao, H.-H.; Richter, F. M.; Kastner, B. & Ficner, R.  et al.​ (2010) 
    Nucleic Acids Research, 38(16) pp. 5581​-5593​.​ DOI: https://doi.org/10.1093/nar/gkq272 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome​
    Fabrizio, P.; Dannenberg, J. ; Dube, P.; Kastner, B.; Stark, H. ; Urlaub, H.   & Lührmann, R. ​ (2009) 
    Molecular Cell, 36(4) pp. 593​-608​.​ DOI: https://doi.org/10.1016/j.molcel.2009.09.040 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​GraFix: sample preparation for single-particle electron cryomicroscopy​
    Kastner, B.; Fischer, N. ; Golas, M. M.; Sander, B.; Dube, P.; Boehringer, D. & Hartmuth, K. et al.​ (2007) 
    Nature Methods, 5(1) pp. 53​-55​.​ DOI: https://doi.org/10.1038/nmeth1139 
    ​Details  DOI 
  • 2007 | Journal Article
    ​ ​Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes​
    Behzadnia, N.; Golas, M. M.; Hartmuth, K.; Sander, B.; Kastner, B.; Deckert, J. & Dube, P. et al.​ (2007) 
    The EMBO Journal, 26(6) pp. 1737​-1748​.​ DOI: https://doi.org/10.1038/sj.emboj.7601631 
    ​Details  DOI 
  • 2006 | Journal Article
    ​ ​Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions​
    Deckert, J.; Hartmuth, K.; Boehringer, D.; Behzadnia, N.; Will, C. L.; Kastner, B. & Stark, H.  et al.​ (2006) 
    Molecular and Cellular Biology, 26(14) pp. 5528​-5543​.​ DOI: https://doi.org/10.1128/MCB.00582-06 
    ​Details  DOI 

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https://publications.goettingen-research-online.de URI: /cris/rp/rp00878
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