Dr. rer. nat. Viacheslav Nikolaev

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  • 2016 | Journal Article | Research Paper | 
    ​ ​Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET​
    Sprenger, J. U.; Bork, N. I.; Herting, J. ; Fischer, T. H.   & Nikolaev, V. O. ​ (2016) 
    PLoS One, 11(12) art. e0167974​.​ DOI: https://doi.org/10.1371/journal.pone.0167974 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Axial tubule junctions control rapid calcium signaling in atria​
    Brandenburg, S. ; Kohl, T. ; Williams, G. S. B.; Gusev, K.; Wagner, E. ; Rog-Zielinska, E. A. & Hebisch, E. et al.​ (2016) 
    Journal of Clinical Investigation, 126(10) pp. 3999​-4015​.​ DOI: https://doi.org/10.1172/JCI88241 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Book Chapter
    ​ ​Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters​
    Bastug, Z.& Nikolaev, V. O. ​ (2015)
    In:​Cheng, Xiaodong​ (Ed.), Cyclic Nucleotide Signaling pp. 98​-115. ​Boca Raton: ​CRC Press. DOI: https://doi.org/10.1201/b18477-10 
    ​Details  DOI 
  • 2015 | Journal Article | Research Paper
    ​ ​Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy​
    Perera, R. K. ; Sprenger, J. U.; Steinbrecher, J. H.; Hübscher, D. ; Lehnart, S. E. ; Abesser, M. & Schuh, K. et al.​ (2015) 
    Circulation Research, 116(8) pp. 1304​-1311​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.116.306082 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | Research Paper | 
    ​ ​In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease​
    Sprenger, J. U.; Perera, R. K. ; Steinbrecher, J. H.; Lehnart, S. E. ; Maier, L. S. ; Hasenfuß, G.   & Nikolaev, V. O. ​ (2015) 
    Nature Communications, 6 art. 6965​.​ DOI: https://doi.org/10.1038/ncomms7965 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Enhanced Expression of beta 3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase​
    Belge, C.; Hammond, J.; Dubois-Deruy, E.; Manoury, B.; Hamelet, J.; Beauloye, C. & Markl, A. et al.​ (2014) 
    Circulation, 129(4) pp. 451​-462​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.113.004940 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes​
    Götz, K. R.; Sprenger, J. U.; Perera, R. K. ; Steinbrecher, J. H.; Lehnart, S. E. ; Kuhn, M. & Gorelik, J. et al.​ (2014) 
    Circulation Research, 114(8) pp. 1235​-1245​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.114.302437 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | Research Paper
    ​ ​Tubulin polymerization disrupts cardiac beta-adrenergic regulation of late I-Na​
    Dybkova, N.; Wagner, S.; Backs, J.; Hund, T. J.; Mohler, P. J.; Sowa, T. & Nikolaev, V. O.  et al.​ (2014) 
    Cardiovascular Research, 103(1) pp. 168​-177​.​ DOI: https://doi.org/10.1093/cvr/cvu120 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Overview | 
    ​ ​Biophysical Techniques for Detection of cAMP and cGMP in Living Cells​
    Sprenger, J. U. & Nikolaev, V. O. ​ (2013) 
    International Journal of Molecular Sciences, 14(4) pp. 8025​-8046​.​ DOI: https://doi.org/10.3390/ijms14048025 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Phosphodiesterase-2 Is Up-Regulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes​
    Mehel, H.; Emons, J.; Vettel, C. ; Wittköpper, K.; Seppelt, D.; Dewenter, M.   & Lutz, S.  et al.​ (2013) 
    Journal of the American College of Cardiology, 62(17) pp. 1596​-1606​.​ DOI: https://doi.org/10.1016/j.jacc.2013.05.057 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Book Chapter
    ​ ​Advances and Techniques to Measure cGMP in Intact Cardiomyocytes​
    Götz, K. R.& Nikolaev, V. O. ​ (2013)
    In:​Krieg, Thomas; Lukowski, Robert​ (Eds.), Guanylate Cyclase and Cyclic GMP. Methods and Protocols pp. 121​-129. ​Totowa, NJ: ​Humana Press. DOI: https://doi.org/10.1007/978-1-62703-459-3_7 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article | Overview
    ​ ​Compartmentation of cAMP signalling in cardiomyocytes in health and disease​
    Perera, R. K. & Nikolaev, V. O. ​ (2013) 
    Acta Physiologica, 207(4) pp. 650​-662​.​ DOI: https://doi.org/10.1111/apha.12077 
    ​Details  DOI  PMID  PMC  WoS 

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Project:  SFB 1002 | A01: cAMP- und cGMP- Mikrodomänen bei Herzhypertrophie und Insuffizienz

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