Prof. Dr. Ulrich Sax

 
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  • 2023 Book Chapter
    ​ ​Reusing Biomedical Data as Agreed – Towards Structured Metadata for Data Use Agreements​
    Bönisch, C.; Hanß, S.; Spicher, N. ; Sax, U.  & Krefting, D. ​ (2023)
    In:​Röhrig, Rainer; Grabe, Niels; Haag, Martin; Hübner, Ursula; Sax, Ulrich; Schmidt, Carsten Oliver; Sedlmayr, Martin, et al.​ (Eds.), German Medical Data Sciences 2023 – Science. Close to People. : Proceedings of the 68th Annual Meeting of the German Association of Medical Informatics, Biometry, and Epidemiology e.V. (gmds) 2023 in Heilbronn, Germany. ​IOS Press. DOI: https://doi.org/10.3233/SHTI230690 
    Details  DOI 
  • 2022 Book Chapter
    ​ ​ToolPool Gesundheitsforschung – A Repository for Software and Services Focused on Supporting Clinical and Epidemiological Research​
    Löbe, M.; Bialke, M.; Bienzeisler, J.; Drepper, J.; Ganslandt, T.; Haderer, S.& Kraska, D. et al.​ (2022)
    In:​Schreier, Günter; Pfeifer, Bernhard; Baumgartner, Martin; Hayn, Dieter​ (Eds.), dHealth 2022 : Proceedings of the 16th Health Informatics Meets Digital Health Conference. ​IOS Press. DOI: https://doi.org/10.3233/SHTI220342 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy​
    Emons, G.; Auslander, N.; Jo, P.; Kitz, J.; Azizian, A.; Hu, Y. & Hess, C. F. et al.​ (2022) 
    British Journal of Cancer,.​ DOI: https://doi.org/10.1038/s41416-022-01842-2 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Open tools for quantitative anonymization of tabular phenotype data: literature review​
    Haber, A. C; Sax, U.   & Prasser, F.​ (2022) 
    Briefings in Bioinformatics, art. bbac440​.​ DOI: https://doi.org/10.1093/bib/bbac440 
    Details  DOI 
  • 2021 Book Chapter
    ​ ​Management of Metadata Types in Basic Cardiological Research​
    Kusch, H. ; Kossen, R. ; Suhr, M.; Freckmann, L.; Weber, L.; Henke, C.& Lehmann, C. et al.​ (2021)
    In:​Röhrig, Rainer; Beißbarth, Tim; König, Jochem; Ose, Claudia; Rauch, Geraldine; Sax, Ulrich; Schreiweis, Björn, et al.​ (Eds.), German Medical Data Sciences 2021: Digital Medicine: Recognize – Understand – Heal pp. 59​-68.  DOI: https://doi.org/10.3233/SHTI210542 
    Details  DOI  PMID  PMC 
  • 2021 Conference Abstract
    ​ ​Sustainable Deployment of Research Infrastructure Components​
    Bender, T.; Parciak, M.; Suhr, M. ; Sax, U.   & Bauer, C. R.​ (2021)
    GMS German Medical Science, ​65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)​, Berlin. DOI: https://doi.org/10.3205/20gmds162 
    Details  DOI 
  • 2021 Research Data
    ​ ​GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072​
    Kusch, H. ; Bauer, C. R.; Bender, T.; Hügel, J. ; Kossen, R. ; Nußbeck, S. Y.& Sax, U. ​ (2021)
    ​GRO.data. DOI: https://doi.org/10.25625/8vukqa 
    Details  DOI 
  • 2021 Conference Abstract
    ​ ​The bumpy road of FAIRification in practice​
    Kusch, H. ; Bauer, C. R.; Bender, T.; Hügel, J. ; Kossen, R. ; Nussbeck, S. Y. & Sax, U. ​ (2021)
    ​66. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 12. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e. V. (TMF)​, virtuell. DOI: https://doi.org/10.3205/21gmds072 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​COVID-19-Forschungsdaten leichter zugänglich machen – Aufbau einer bundesweiten Informationsinfrastruktur​
    Schmidt, C. O.; Fluck, J.; Golebiewski, M.; Grabenhenrich, L.; Hahn, H.; Kirsten, T. & Klammt, S. et al.​ (2021) 
    Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz,.​ DOI: https://doi.org/10.1007/s00103-021-03386-x 
    Details  DOI 
  • 2020 Preprint
    ​ ​menoci: Lightweight Extensible Web Portal enabling FAIR Data Management for Biomedical Research Projects​
    Suhr, M. ; Lehmann, C.; Bauer, C. R.; Bender, T.; Knopp, C.; Freckmann, L.& Hansen, B. Ö. et al.​ (2020). DOI: https://doi.org/10.48550/arXiv.2002.06161 
    Details  DOI  arXiv 
  • 2020 Journal Article
    ​ ​Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects​
    Umbach, N.; Beißbarth, T. ; Bleckmann, A.; Duttge, G.; Flatau, L.; König, A. & Kuhn, J. et al.​ (2020) 
    European Neuropsychopharmacology31 pp. 1​-15​.​ DOI: https://doi.org/10.1016/j.euroneuro.2019.09.008 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article
    ​ ​Applying FAIRness: Redesigning a Biomedical Informatics Research Data Management Pipeline​
    Parciak, M. ; Bender, T.; Sax, U.   & Bauer, C. R. ​ (2020) 
    Methods of Information in Medicine58(06) pp. 229​-234​.​ DOI: https://doi.org/10.1055/s-0040-1709158 
    Details  DOI 
  • 2019 Book Chapter
    ​ ​Cardiac Tissue Engineering as Use Case to Connect Biomedical Research Laboratories to an Emerging Global Data Infrastructure​
    Suhr, M. ; Umbach, N.; Meyer, T. ; Zimmermann, W.-H.  & Sax, U. ​ (2019)
    In:​Ohno-Machado, Lucila; Séroussi, Brigitte​ (Eds.), MEDINFO 2019: Health and Wellbeing e-Networks for All pp. 363​-367.  DOI: https://doi.org/10.3233/SHTI190244 
    Details  DOI  PMID  PMC 
  • 2019 Book Chapter
    ​ ​Towards Structured Data Quality Assessment in the German Medical Informatics Initiative: Initial Approach in the MII Demonstrator Study​
    Kamdje-Wabo, G.; Gradinger, T.; Löbe, M.; Lodahl, R.; Seuchter, S. A.; Sax, U.  & Ganslandt, T.​ (2019)
    In:​Ohno-Machado, Lucila; Séroussi, Brigitte​ (Eds.), MEDINFO 2019: Health and Wellbeing e-Networks for All pp. 1508​-1509.  DOI: https://doi.org/10.3233/SHTI190508 
    Details  DOI  PMID  PMC 
  • 2019 Book Chapter
    ​ ​Molecular diagnosis and therapy prediction using biomarkers in the era of next-generation sequencing​
    Perera-Bel, J.  & Beißbarth, T. ​ (2019)
    In:​Duttge, Gunnar; Sax, Ulrich; Schweda, Mark; Umbach, Nadine​ (Eds.), Next-generation medicine : ethische, rechtliche und technologische Fragen genomischer Hochdurchsatzdaten in der klinischen Praxis pp. 11​-19. ​Tübingen: ​Mohr Siebeck.
    Details 
  • 2018 Journal Article
    ​ ​Concept acquisition and improved in-database similarity analysis for medical data​
    Wiese, I.; Sarna, N.; Wiese, L. ; Tashkandi, A. & Sax, U. ​ (2018) 
    Distributed and Parallel Databases37(2) pp. 297​-321​.​ DOI: https://doi.org/10.1007/s10619-018-7249-x 
    Details  DOI 
  • 2018 Conference Proceedings
    ​ ​German medical data sciences: ​a learning healthcare system : proceedings of the 63rd annual meeting of the German Association of Medical Informatics, Biometry and Epidemiology (gmds e.V.) 2018 in Osnabrück, Germany -- GMDS 2018​
    Hübner, U.; Sax, U. ; Prokosch, H.-U.; Breil, B.; Binder, H.; Zapf, A.& Strahwald, B. et al.​ (Eds.) (2018)
    63rd Annual Meeting of the German Association of Medical Informatics, Biometry and Epidemiology​, Osnabrück.
    Amsterdam​: IOS Press.
    Details 
  • 2018 Conference Abstract
    ​ ​Application of basic research data management with FAIRDOM/SEEK from a medical informatics perspective​
    Bauer, C. R.; Knopp, C.; Bender, T.; Kusch, H.   & Sax, U. ​ (2018)
    ​63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)​, Osnabrück. DOI: https://doi.org/10.3205/18gmds093 
    Details  DOI 
  • 2018 Conference Abstract
    ​ ​Usage of persistent identifiers to implement the FAIR guiding principles in medical research data management systems​
    Knopp, C.; Bauer, C. R.; Kusch, H.   & Sax, U. ​ (2018)
    ​63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)​, Osnabrück. DOI: https://doi.org/10.3205/18gmds172 
    Details  DOI 
  • 2018 Conference Abstract
    ​ ​PROV@TOS, a Java Wrapper to capture provenance for Talend Open Studio jobs​
    Parciak, M.; Bauer, C. R.; Lodahl, R.; Thoms, C.; Kusch, H. ; Rey, S. & Sax, U. ​ (2018)
    GMS German Medical Science, , Osnabrück. DOI: https://doi.org/10.3205/18gmds096 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​Whither systems medicine?​
    Apweiler, R.; Beißbarth, T. ; Berthold, M. R.; Blüthgen, N.; Burmeister, Y.; Dammann, O. & Deutsch, A. et al.​ (2018) 
    Experimental & Molecular Medicine50(3) art. e453​.​ DOI: https://doi.org/10.1038/emm.2017.290 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | 
    ​ ​HiGHmed – An Open Platform Approach to Enhance Care and Research across Institutional Boundaries​
    Haarbrandt, B.; Schreiweis, B.; Rey, S.; Sax, U. ; Scheithauer, S. ; Rienhoff, O.   & Knaup-Gregori, P. et al.​ (2018) 
    Methods of Information in Medicine57(S 01) pp. e66​-e81​.​ DOI: https://doi.org/10.3414/ME18-02-0002 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​The Use of Genomic Information In Medical Practice: A Survey on People’s Knowledge, Expectations, And Fears​
    Flatau, L.; Umbach, N.; Sax, U. ; Beißbarth, T. ; Duttge, G.; Schweda, M. & Schulze, T.​ (2017) 
    European Neuropsychopharmacology27 art. S369​.​ DOI: https://doi.org/10.1016/j.euroneuro.2016.09.396 
    Details  DOI 
  • 2017 Conference Paper
    ​ ​Technical Aspects of Data Provenance in Clinical Trials​
    Parciak, M. ; Bauer, C. R.; Baum, B.; Kusch, H.   & Sax, U. ​ (2017)
    ​62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)​, Oldenburg. DOI: https://doi.org/10.3205/17gmds155 
    Details  DOI 
  • 2017 Journal Article | Overview
    ​ ​Opinion paper: Data provenance challenges in biomedical research​
    Baum, B. ; Bauer, C. R. ; Franke, T. ; Kusch, H. ; Parciak, M. ; Rottmann, T.   & Umbach, N.  et al.​ (2017) 
    Information Technology59(4).​ DOI: https://doi.org/10.1515/itit-2016-0031 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases​
    Bauer, C. R.; Knecht, C.; Fretter, C.; Baum, B.; Jendrossek, S.; Ruehlemann, M. & Heinsen, F.-A. et al.​ (2017) 
    Briefings in Bioinformatics18(3) pp. 479​-487​.​ DOI: https://doi.org/10.1093/bib/bbw024 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Conference Paper
    ​ ​A validatable data management solution for multi-center research consortia: research data management with openBIS​
    Knopp, C.; Bauer, C. R. K. D. ; Baum, B. ; Löhnhardt, B.; Nietert, M. M. ; Beißbarth, T.   & Sax, U. ​ (2016)
    ​Conference: HEC 2016 - Health-Exploring Complexity: An Interdisciplinairy Systems Approach​, München.
    Details 
  • 2016 Conference Abstract
    ​ ​Neoadjuvant therapy in rectal cancer - challenges of biobanking tumor biopsies taken prior to treatment​
    Jo, P. ; Gusky, L.; Nietert, M. M. ; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016)
    Oncology Research and Treatment39 
    Basel​: Karger.
    Details  WoS 
  • 2016 Journal Article | 
    ​ ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​
    Jo, P. ; Nietert, M. M. ; Gusky, L.; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016) 
    Scientific Reports6 art. 35589​.​ DOI: https://doi.org/10.1038/srep35589 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Integrated Data Repository Toolkit (IDRT): ​A Suite of Programs to Facilitate Health Analytics on Heterogeneous Medical Data​
    Bauer, C. R. K. D. ; Ganslandt, T.; Baum, B. ; Christoph, J.; Engel, I.; Löbe, M. & Mate, S. et al.​ (2016) 
    Methods of Information in Medicine55(2) pp. 125​-135​.​ DOI: https://doi.org/10.3414/ME15-01-0082 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​The Integrated Data Repository Toolkit (IDRT): accelerating translational research infrastructures​
    Bauer, C.; Ganslandt, T.; Baum, B.; Christoph, J.; Engel, I.; Löbe, M. & Mate, S. et al.​ (2015) 
    Journal of Clinical Bioinformatics5(Suppl 1) art. S6​.​ DOI: https://doi.org/10.1186/2043-9113-5-S1-S6 
    Details  DOI 
  • 2013 Conference Abstract
    ​ ​Aspekte des Managements von NGS-Daten am Standort Göttingen​
    Löhnhardt, B.; Bohrer, R. & Sax, U. ​ (2013)
    ​GMDS 2013. 58. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V.​, Lübeck. DOI: https://doi.org/10.3205/13gmds136 
    Details  DOI 
  • 2012 Journal Article | Research Paper
    ​ ​Solutions for biomedical grid computing-Case studies from the D-Grid project Services@MediGRID​
    Dickmann, F.; Falkner, J.; Gunia, W.; Hampe, J.; Hausmann, M.; Herrmann, A. M. & Kepper, N. et al.​ (2012) 
    Journal of Computational Science3(5) pp. 280​-297​.​ DOI: https://doi.org/10.1016/j.jocs.2011.06.006 
    Details  DOI  WoS 
  • 2011 Journal Article | 
    ​ ​Unlocking Data for Clinical Research - The German i2b2 Experience​
    Ganslandt, T.; Mate, S.; Helbing, K.; Sax, U.   & Prokosch, H. U.​ (2011) 
    Applied Clinical Informatics2(1) pp. 116​-127​.​ DOI: https://doi.org/10.4338/ACI-2010-09-CR-0051 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | 
    ​ ​Quality of human-computer interaction - results of a national usability survey of hospital-IT in Germany​
    Bundschuh, B. B.; Majeed, R. W.; Buerkle, T.; Kuhn, K.; Sax, U. ; Seggewies, C. & Vosseler, C. et al.​ (2011) 
    BMC Medical Informatics and Decision Making11 art. 69​.​ DOI: https://doi.org/10.1186/1472-6947-11-69 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | 
    ​ ​Frequency and spectrum of congenital heart defects among live births in Germany​
    Schwedler, G.; Lindinger, A.; Lange, P. E.; Sax, U. ; Olchvary, J.; Peters, B. & Bauer, U. et al.​ (2011) 
    Clinical Research in Cardiology100(12) pp. 1111​-1117​.​ DOI: https://doi.org/10.1007/s00392-011-0355-7 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Conference Paper
    ​ ​An interdisciplinary practical course on the application of grid computing​
    Rings, T. ; Grabowski, J. ; Lauer, G. ; Sax, U. ; Aschenbrenner, A. ; Kálmán, T.   & Meyer, J. et al.​ (2010)
    ​IEEE EDUCON 2010 Conference pp. 943​-951. ​Education Engineering (EDUCON)​, Madrid.
    IEEE. DOI: https://doi.org/10.1109/educon.2010.5492477 
    Details  DOI 
  • 2010 Journal Article | 
    ​ ​Einsatz des i2b2 Frameworks für den Secondary Use in Medizinischen Forschungsverbünden​
    Helbing, K.; Reimann, L.; Zeiss, S. & Sax, U. ​ (2010) 
    GMS Medizinische Informatik, Biometrie und Epidemiologie,(257) pp. 1​-6​.​
    Details 
  • 2010 Journal Article | 
    ​ ​Usabil-IT : Usability der Krankenhaus-IT in Deutschland​
    Bundschuh, B. B.; Bürkle, T.; Kuhn, K.; Majeed, R.; Sax, U. ; Seggewies, C. & Vosseler, C. et al.​ (2010) 
    GMS Medizinische Informatik, Biometrie und Epidemiologie,(195) pp. 1​-14​.​
    Details 
  • 2010 Journal Article
    ​ ​Mutated KRAS Results in Overexpression of DUSP4, a MAP-Kinase Phosphatase, and SMYD3, a Histone Methyltransferase, in Rectal Carcinomas​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Camps, J.; Jo, P. ; Emons, G.   & Gehoff, A. et al.​ (2010) 
    Genes Chromosomes and Cancer49(11) pp. 1024​-1034​.​ DOI: https://doi.org/10.1002/gcc.20811 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​A Data Protection Scheme for Medical Research Networks Review after Five Years of Operation​
    Helbing, K.; Demiroglu, S. Y. ; Rakebrandt, F.; Pommerening, K.; Rienhoff, O. & Sax, U. ​ (2010) 
    Methods of Information in Medicine49(6) pp. 601​-607​.​ DOI: https://doi.org/10.3414/ME09-02-0058 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​Registers for networked medical research in Germany​
    Stausberg, J.; Altmann, U.; Antony, G.; Drepper, J.; Sax, U.   & Schuett, A.​ (2010) 
    Applied Clinical Informatics1(4) pp. 408​-418​.​ DOI: https://doi.org/10.4338/ACI-2010-04-RA-0024 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​IT Infrastructure Components for Biobanking​
    Prokosch, H. U.; Beck, A.; Ganslandt, T.; Hummel, M.; Kiehntopf, M.; Sax, U.   & Ueckert, F. et al.​ (2010) 
    Applied Clinical Informatics1(4) pp. 419​-429​.​ DOI: https://doi.org/10.4338/ACI-2010-05-RA-0034 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​MediGRID: Towards a user friendly secured grid infrastructure​
    Krefting, D. ; Bart, J.; Beronov, K.; Dzhimova, O.; Falkner, J.; Hartung, M. & Hoheisel, A. et al.​ (2009) 
    Future Generation Computer Systems25(3) pp. 326​-336​.​ DOI: https://doi.org/10.1016/j.future.2008.05.005 
    Details  DOI 
  • 2008 Conference Abstract
    ​ ​The Tele-radio-logical network for central interpretation and archiving of MRT-image date: 3 years experience in cardiac-vascular research grouping​
    Kuehne, T.; Mueller, S.; Sarikouch, S.; Beerbaum, P.; Gutberlet, M.; Franke, D. & Sax, U.  et al.​ (2008)
    Clinical Research in Cardiology97(9) 
    Heidelberg​: Dr Dietrich Steinkopff Verlag.
    Details  WoS 
  • 2008 Conference Abstract
    ​ ​The centralized management for an evaluation and failing of digital echo-cardio graphical data for a multicenter study​
    Rentzsch, A.; Boettler, P.; Vogel, M.; Vogt, M.; Schoeber, M.; Sax, U.   & Mueller, S. et al.​ (2008)
    Clinical Research in Cardiology97(9) 
    Heidelberg​: Dr Dietrich Steinkopff Verlag.
    Details  WoS 
  • 2005 Journal Article
    ​ ​Wireless Technology Infrastructures for Authentication of Patients: PKI that Rings​
    Sax, U. ​ (2005) 
    Journal of the American Medical Informatics Association12(3) pp. 263​-268​.​ DOI: https://doi.org/10.1197/jamia.M1681 
    Details  DOI 

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