Prof. Dr. Hauke Hillen

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Bögershausen, Nina, Hannah E. Krawczyk, Rami A. Jamra, Sheng‐Jia Lin, Gökhan Yigit, Irina Hüning, Anna M. Polo et al. "WARS1 and SARS1: Two tRNA synthetases implicated in autosomal recessive microcephaly​." ​Human Mutation ​43, no. 10 (2022): ​1454​-1471​. ​https://doi.org/10.1002/humu.24430.
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Overview | 
    ​ ​Bhatta, Arjun, and Hauke S. Hillen. "Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden​." ​Biospektrum ​28, no. 1 (2022): ​18​-20​. ​https://doi.org/10.1007/s12268-022-1711-z.
    ​Details  DOI 
  • 2022 | Journal Article | Overview | 
    ​ ​Bhatta, Arjun, and Hauke S. Hillen. "Structural and mechanistic basis of RNA processing by protein-only ribonuclease P enzymes​." ​Trends in Biochemical Sciences ​47, no. 11 (2022): ​965​-977​. ​https://doi.org/10.1016/j.tibs.2022.05.006.
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  • 2021 | Preprint
    ​ ​Kabinger, Florian, Carina Stiller, Jana Schmitzová, Christian Dienemann, Hauke S. Hillen, Claudia Höbartner, and Patrick Cramer​. "Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis​." ​Preprint, submitted ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/258 https://sfb1190.med.uni-goettingen.de/production/literature/publications/145 https://for2848.gwdguser.de/literature/publications/12. https://doi.org/10.1101/2021.05.11.443555.
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Jochheim, Florian A., Dimitry Tegunov, Hauke S. Hillen, Jana Schmitzova, Goran Kokic, Christian Dienemann, and Patrick Cramer​. "Dimeric form of SARS-CoV-2 polymerase​." ​Preprint, submitted ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/291 https://sfb1190.med.uni-goettingen.de/production/literature/publications/147 https://for2848.gwdguser.de/literature/publications/11. https://doi.org/10.1101/2021.03.23.436644.
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Hillen, Hauke S., Elena Lavdovskaia, Franziska Nadler, Elisa Hanitsch, Andreas Linden, Katherine E. Bohnsack, Henning Urlaub, and Ricarda Richter-Dennerlein​. "Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling​." ​Preprint, submitted ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/241 https://sfb1190.med.uni-goettingen.de/production/literature/publications/225. https://doi.org/10.1101/2021.03.17.435767.
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Bhatta, Arjun, Christian Dienemann, Patrick Cramer, and Hauke S. Hillen. "Structural basis of RNA processing by human mitochondrial RNase P​." ​Nature Structural & Molecular Biology ​28, no. 9 (2021): ​713​-723​. ​https://doi.org/10.1038/s41594-021-00637-y.
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Lavdovskaia, Elena, Hauke S. Hillen, and Ricarda Richter-Dennerlein. "Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis​." ​Trends in Cell Biology (2021): . ​https://doi.org/10.1016/j.tcb.2021.09.004.
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  • 2021 | Journal Article | Research Paper | 
    ​ ​Jochheim, Florian A., Dimitry Tegunov, Hauke S. Hillen, Jana Schmitzová, Goran Kokic, Christian Dienemann, and Patrick Cramer. "The structure of a dimeric form of SARS-CoV-2 polymerase​." ​Communications Biology ​4, no. 1 (2021): ​999​. ​https://doi.org/10.1038/s42003-021-02529-9.
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Kokic, Goran, Hauke S. Hillen, Dimitry Tegunov, Christian Dienemann, Florian Seitz, Jana Schmitzova, Lucas Farnung, Aaron Siewert, Claudia Höbartner, and Patrick Cramer. "Mechanism of SARS-CoV-2 polymerase stalling by remdesivir​." ​Nature Communications ​12, no. 1 (2021): ​279​. ​https://doi.org/10.1038/s41467-020-20542-0.
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Kabinger, Florian, Carina Stiller, Jana Schmitzová, C. Dienemann, Goran Kokic, Hauke S. Hillen, Claudia Höbartner, and Patrick Cramer. "Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis​." ​Nature Structural & Molecular Biology (2021): . ​https://doi.org/10.1038/s41594-021-00651-0.
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  • 2021 | Journal Article | Research Paper
    ​ ​Hillen, Hauke S., Dmitriy A. Markov, Ireneusz D. Wojtas, Katharina B. Hofmann, Michael Lidschreiber, Andrew T. Cowan, Julia L. Jones, Dmitry Temiakov, Patrick Cramer, and Michael Anikin. "The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs​." ​Proceedings of the National Academy of Sciences ​118, no. 15 (2021): ​e2009329118​. ​https://doi.org/10.1073/pnas.2009329118.
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Hillen, Hauke S.. "Structure and function of SARS-CoV-2 polymerase​." ​Current Opinion in Virology ​48 (2021): ​82​-90​. ​https://doi.org/10.1016/j.coviro.2021.03.010.
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Bonekamp, Nina A., Bradley Peter, Hauke S. Hillen, Andrea Felser, Tim Bergbrede, Axel Choidas, Moritz Horn et al. "Small-molecule inhibitors of human mitochondrial DNA transcription​." ​Nature ​588, no. 7839 (2020): ​712-716​-716​. ​https://doi.org/10.1038/s41586-020-03048-z.
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Hillen, Hauke S., Goran Kokic, Lucas Farnung, Christian Dienemann, Dimitry Tegunov, and Patrick Cramer. "Structure of replicating SARS-CoV-2 polymerase​." ​Nature ​584, no. 7819 (2020): ​154-156​-156​. ​https://doi.org/10.1038/s41586-020-2368-8.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Grimm, Clemens, Hauke S. Hillen, Kristina Bedenk, Julia Bartuli, Simon Neyer, Qian Zhang, Alexander Hüttenhofer et al. "Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes​." ​Cell ​179, no. 7 (2019): ​1537​-1550​. ​https://doi.org/10.1016/j.cell.2019.11.024.
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Hillen, Hauke S., Julia Bartuli, Clemens Grimm, Christian Dienemann, Kristina Bedenk, Aladar A Szalay, Utz Fischer, and Patrick Cramer. "Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes​." ​Cell ​179, no. 7 (2019): ​1525​-1536​. ​https://doi.org/10.1016/j.cell.2019.11.023.
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Hillen, Hauke S., Dmitry Temiakov, and Patrick Cramer. "Structural basis of mitochondrial transcription​." ​Nature Structural & Molecular Biology ​25, no. 9 (2018): ​754​-765​. ​https://doi.org/10.1038/s41594-018-0122-9.
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Hillen, Hauke S., Andrey V. Parshin, Karen Agaronyan, Yaroslav I. Morozov, James J. Graber, Aleksandar Chernev, Kathrin Schwinghammer et al. "Mechanism of Transcription Anti-termination in Human Mitochondria​." ​Cell ​171, no. 5 (2017): ​1082​-1093​. ​https://doi.org/10.1016/j.cell.2017.09.035.
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Hillen, Hauke S., Yaroslav I. Morozov, Azadeh Sarfallah, Dmitry Temiakov, and Patrick Cramer. "Structural Basis of Mitochondrial Transcription Initiation​." ​Cell ​171, no. 5 (2017): ​1072​-1081​. ​https://doi.org/10.1016/j.cell.2017.10.036.
    ​Details  DOI  PMID  PMC 

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