Prof. Dr. Hauke Hillen

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  • 2022 Journal Article | Research Paper | 
    ​ ​Bögershausen, Nina, et al. "WARS1 and SARS1: Two tRNA synthetases implicated in autosomal recessive microcephaly​." ​Human Mutation, vol. 43, no. 10, ​2022, pp. 1454​-1471​, ​doi: 10.1002/humu.24430. 
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  • 2022 Journal Article | Overview | 
    ​ ​Bhatta, Arjun, and Hauke S. Hillen. "Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden​." ​Biospektrum, vol. 28, no. 1, ​2022, pp. 18​-20​, ​doi: 10.1007/s12268-022-1711-z. 
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  • 2022 Journal Article | Overview | 
    ​ ​Bhatta, Arjun, and Hauke S. Hillen. "Structural and mechanistic basis of RNA processing by protein-only ribonuclease P enzymes​." ​Trends in Biochemical Sciences, vol. 47, no. 11, ​2022, pp. 965​-977​, ​doi: 10.1016/j.tibs.2022.05.006. 
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  • 2021 Preprint
    ​ ​Kabinger, Florian, et al. "Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis​." ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/258 https://sfb1190.med.uni-goettingen.de/production/literature/publications/145 https://for2848.gwdguser.de/literature/publications/12. doi: 10.1101/2021.05.11.443555. 
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  • 2021 Preprint
    ​ ​Jochheim, Florian A., et al. "Dimeric form of SARS-CoV-2 polymerase​." ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/291 https://sfb1190.med.uni-goettingen.de/production/literature/publications/147 https://for2848.gwdguser.de/literature/publications/11. doi: 10.1101/2021.03.23.436644. 
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  • 2021 Preprint
    ​ ​Hillen, Hauke S., et al. "Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling​." ​​2021. ​https://mbexc.uni-goettingen.de/literature/publications/241 https://sfb1190.med.uni-goettingen.de/production/literature/publications/225. doi: 10.1101/2021.03.17.435767. 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Bhatta, Arjun, et al. "Structural basis of RNA processing by human mitochondrial RNase P​." ​Nature Structural & Molecular Biology, vol. 28, no. 9, ​2021, pp. 713​-723​, ​doi: 10.1038/s41594-021-00637-y. 
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  • 2021 Journal Article | Overview | 
    ​ ​Lavdovskaia, Elena, Hauke S. Hillen, and Ricarda Richter-Dennerlein. "Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis​." ​Trends in Cell Biology, ​2021, , ​doi: 10.1016/j.tcb.2021.09.004. 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Jochheim, Florian A., et al. "The structure of a dimeric form of SARS-CoV-2 polymerase​." ​Communications Biology, vol. 4, no. 1, ​2021, , ​doi: 10.1038/s42003-021-02529-9. 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Kokic, Goran, et al. "Mechanism of SARS-CoV-2 polymerase stalling by remdesivir​." ​Nature Communications, vol. 12, no. 1, ​2021, , ​doi: 10.1038/s41467-020-20542-0. 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Kabinger, Florian, et al. "Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis​." ​Nature Structural & Molecular Biology, ​2021, , ​doi: 10.1038/s41594-021-00651-0. 
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  • 2021 Journal Article | Research Paper
    ​ ​Hillen, Hauke S., et al. "The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs​." ​Proceedings of the National Academy of Sciences, vol. 118, no. 15, ​2021, p. e2009329118​, ​doi: 10.1073/pnas.2009329118. 
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  • 2021 Journal Article | Overview | 
    ​ ​Hillen, Hauke S.. "Structure and function of SARS-CoV-2 polymerase​." ​Current Opinion in Virology, vol. 48, ​2021, pp. 82​-90​, ​doi: 10.1016/j.coviro.2021.03.010. 
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  • 2020 Journal Article | Research Paper
    ​ ​Bonekamp, Nina A., et al. "Small-molecule inhibitors of human mitochondrial DNA transcription​." ​Nature, vol. 588, no. 7839, ​2020, pp. 712-716​-716​, ​doi: 10.1038/s41586-020-03048-z. 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Hillen, Hauke S., et al. "Structure of replicating SARS-CoV-2 polymerase​." ​Nature, vol. 584, no. 7819, ​2020, pp. 154-156​-156​, ​doi: 10.1038/s41586-020-2368-8. 
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  • 2019 Journal Article | Research Paper
    ​ ​Grimm, Clemens, et al. "Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes​." ​Cell, vol. 179, no. 7, ​2019, pp. 1537​-1550​, ​doi: 10.1016/j.cell.2019.11.024. 
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  • 2019 Journal Article | Research Paper
    ​ ​Hillen, Hauke S., et al. "Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes​." ​Cell, vol. 179, no. 7, ​2019, pp. 1525​-1536​, ​doi: 10.1016/j.cell.2019.11.023. 
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  • 2018 Journal Article
    ​ ​Hillen, Hauke S., Dmitry Temiakov, and Patrick Cramer. "Structural basis of mitochondrial transcription​." ​Nature Structural & Molecular Biology, vol. 25, no. 9, ​2018, pp. 754​-765​, ​doi: 10.1038/s41594-018-0122-9. 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Hillen, Hauke S., et al. "Mechanism of Transcription Anti-termination in Human Mitochondria​." ​Cell, vol. 171, no. 5, ​2017, pp. 1082​-1093​, ​doi: 10.1016/j.cell.2017.09.035. 
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  • 2017 Journal Article
    ​ ​Hillen, Hauke S., et al. "Structural Basis of Mitochondrial Transcription Initiation​." ​Cell, vol. 171, no. 5, ​2017, pp. 1072​-1081​, ​doi: 10.1016/j.cell.2017.10.036. 
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