Prof. Dr. Jörg Großhans

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  • 2020 | Journal Article
    ​ ​The Emergent Yo-yo Movement of Nuclei Driven by Cytoskeletal Remodeling in Pseudo-synchronous Mitotic Cycles​
    Lv, Z.; Rosenbaum, J.; Mohr, S.; Zhang, X.; Kong, D. ; Preiß, H.   & Kruss, S.  et al.​ (2020) 
    Current Biology, 30(13) pp. 2564​-2573.e5​.​ DOI: https://doi.org/10.1016/j.cub.2020.04.078 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Fluorescence fluctuation analysis reveals PpV dependent Cdc25 protein dynamics in living embryos​
    Liu, B. ; Gregor, I. ; Müller, H.-A. & Großhans, J. ​ (2020) 
    PLoS Genetics, 16(4) pp. e1008735​.​ DOI: https://doi.org/10.1371/journal.pgen.1008735 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Exfoliated near infrared fluorescent silicate nanosheets for (bio)photonics​
    Selvaggio, G.; Chizhik, A. ; Nißler, R.; Kuhlemann, l.; Meyer, D. ; Vuong, L. & Preiß, H.  et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-020-15299-5 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​A Link between Deoxyribonucleotide Metabolites and Embryonic Cell-Cycle Control​
    Liu, B. ; Winkler, F.; Herde, M.; Witte, C.-P. & Großhans, J. ​ (2019) 
    Current Biology, 29(7) pp. 1187​-1192.e3​.​ DOI: https://doi.org/10.1016/j.cub.2019.02.021 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​The role of dNTP metabolites in control of the embryonic cell cycle​
    Liu, B.   & Großhans, J. ​ (2019) 
    Cell Cycle, 18(21) pp. 2817​-2827​.​ DOI: https://doi.org/10.1080/15384101.2019.1665948 
    ​Details  DOI 
  • 2019 | Preprint
    ​ ​Exfoliated near infrared fluorescent CaCuSi 4 O 10 nanosheets with ultra-high photostability and brightness for biological imaging​
    Selvaggio, G.; Preiß, H. ; Chizhik, A. ; Nißler, R.; Mann, F. A.; Lv, Z.& Oswald, T. A.  et al.​ (2019). DOI: https://doi.org/10.1101/710384 
    ​Details  DOI 
  • 2019 | Preprint
    ​ ​The emergent Yo-yo movement of nuclei driven by collective cytoskeletal remodeling in pseudo-synchronous mitotic cycles​
    Lv, Z.; Rosenbaum, J.; Zhang, X.; Mohr, S.; Preiß, H. ; Kruss, S.  & Alim, K. et al.​ (2019). DOI: https://doi.org/10.1101/662965 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Multiple Functions of the Essential Gene PpV in Drosophila Early Development​
    Liu, B. ; Sung, H.-w. & Großhans, J. ​ (2019) 
    G3: Genes, Genomes, Genetics, 9(11) pp. 3583​-3593​.​ DOI: https://doi.org/10.1534/g3.119.400662 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Nanobody‐Conjugated Nanotubes for Targeted Near‐Infrared In Vivo Imaging and Sensing​
    Mann, F. A.; Lv, Z.; Großhans, J. ; Opazo, F.   & Kruss, S. ​ (2019) 
    Angewandte Chemie International Edition, 58(33) pp. 11469​-11473​.​ DOI: https://doi.org/10.1002/anie.201904167 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​A ‘molecular guillotine’ reveals the interphase function of Kinesin-5​
    Lv, Z.; Rosenbaum, J.; Aspelmeier, T.   & Großhans, J. ​ (2018) 
    Journal of Cell Science, 131(3) pp. jcs210583​.​ DOI: https://doi.org/10.1242/jcs.210583 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Dynamics of cortical domains in early Drosophila development​
    Schmidt, A. & Grosshans, J. ​ (2018) 
    Journal of Cell Science, 131(7) pp. jcs212795​.​ DOI: https://doi.org/10.1242/jcs.212795 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Localization and translation control of slam in Drosophila cellularization​
    Yan, S.   & Großhans, J. ​ (2018) 
    Fly, 12(3-4) pp. 191​-198​.​ DOI: https://doi.org/10.1080/19336934.2018.1520574 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Expression of lamina proteins Lamin and Kugelkern suppresses stem cell proliferation​
    Petrovsky, R.   & Großhans, J. ​ (2018) 
    Nucleus, 9(1) pp. 104​-118​.​ DOI: https://doi.org/10.1080/19491034.2017.1412028 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​ELMO and Sponge specify subapical restriction of Canoe and formation of the subapical domain in early Drosophila embryos​
    Schmidt, A.; Lv, Z. & Großhans, J. ​ (2018) 
    Development, 145(2) pp. dev157909​.​ DOI: https://doi.org/10.1242/dev.157909 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Overexpression of the lamina proteins Lamin and Kugelkern induces specific ultrastructural alterations in the morphology of the nuclear envelope of intestinal stem cells and enterocytes​
    Petrovsky, R. ; Krohne, G. & Großhans, J. ​ (2018) 
    European Journal of Cell Biology, 97(2) pp. 102​-113​.​ DOI: https://doi.org/10.1016/j.ejcb.2018.01.002 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Mechanical Model of Nuclei Ordering in Drosophila Embryos Reveals Dilution of Stochastic Forces​
    Kaiser, F.; Lv, Z.; Marques Rodrigues, D.; Rosenbaum, J.; Aspelmeier, T. ; Großhans, J.   & Alim, K.​ (2018) 
    Biophysical Journal, 114(7) pp. 1730​-1740​.​ DOI: https://doi.org/10.1016/j.bpj.2018.02.018 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Rapid nonlinear image scanning microscopy​
    Gregor, I. ; Spiecker, M.; Petrovsky, R. ; Großhans, J. ; Ros, R. & Enderlein, J. ​ (2017) 
    Nature Methods, 14(11) pp. 1087​-1089​.​ DOI: https://doi.org/10.1038/nmeth.4467 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Mechanical Properties of a Drosophila Larval Chordotonal Organ​
    Prahlad, A.; Spalthoff, C. ; Kong, D. ; Großhans, J. ; Göpfert, M. C.   & Schmidt, C. F. ​ (2017) 
    Biophysical Journal, 113(12) pp. 2796​-2804​.​ DOI: https://doi.org/10.1016/j.bpj.2017.08.061 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Single-Cell Defects Cause a Long-Range Mechanical Response in a Confluent Epithelial Cell Layer​
    Karsch, S.; Kong, D. ; Großhans, J.   & Janshoff, A. ​ (2017) 
    Biophysical Journal, 113(12) pp. 2601​-2608​.​ DOI: https://doi.org/10.1016/j.bpj.2017.10.025 
    ​Details  DOI 
  • 2017 | Review
    ​ ​Forces directing germ-band extension in Drosophila embryos​
    Kong, D.; Wolf, F.  & Großhans, J. ​ (2017)
    Mechanisms of Development, 144​ pp. 11​-22​.​ DOI: https://doi.org/10.1016/j.mod.2016.12.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Slam protein dictates subcellular localization and translation of its own mRNA​
    Yan, S. ; Acharya, S.; Gröning, S.   & Großhans, J. ​ (2017) 
    PLOS Biology, 15(12) art. e2003315​.​ DOI: https://doi.org/10.1371/journal.pbio.2003315 
    ​Details  DOI  PMID  PMC 
  • 2017 | Book Chapter
    ​ ​Link of Zygotic Genome Activation and Cell Cycle Control​
    Liu, B.  & Großhans, J. ​ (2017)
    In:​Lee, K.​ (Ed.), Zygotic genome activation: methods and protocols pp. 11​-30. ​New York: ​Humana Press. DOI: https://doi.org/10.1007/978-1-4939-6988-3_2 
    ​Details  DOI  PMID  PMC 
  • 2016 | Conference Abstract
    ​ ​Mechanical properties of the lch5 organ of Drosophila.​
    Prahlad, A.; Spalthoff, C.; Warren, B.; Kong, D.; Grosshans, J. ; Göpfert, M. C.   & Schmidt, C. F.​ (2016)
    Molecular Biology of the Cell, 27 ​Annual Meeting of the American-Society-for-Cell-Biology (ASCB)​, San Francisco, CA.
    Bethesda​: Amer Soc Cell Biology.
    ​Details  WoS 
  • 2016 | Journal Article | Letter Note
    ​ ​A Radial Actin Network in Apical Constriction​
    Lv, Z. & Grosshans, J. ​ (2016) 
    Developmental Cell, 39(3) pp. 280​-282​.​ DOI: https://doi.org/10.1016/j.devcel.2016.10.017 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Fluctuation Analysis of Centrosomes Reveals a Cortical Function of Kinesin-1​
    Winkler, F.; Gummalla, M.; Kuenneke, L.; Lv, Z.; Zippelius, A. ; Aspelmeier, T. & Grosshans, J. ​ (2015) 
    Biophysical Journal, 109(5) pp. 856​-868​.​ DOI: https://doi.org/10.1016/j.bpj.2015.07.044 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​The Mechanical Properties of Early Drosophila Embryos Measured by High-Speed Video Microrheology​
    Wessel, A. D.; Gumalla, M.; Großhans, J.   & Schmidt, C. ​ (2015) 
    Biophysical Journal, 108(8) pp. 1899​-1907​.​ DOI: https://doi.org/10.1016/j.bpj.2015.02.032 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​The glucosyltransferase Xiantuan of the endoplasmic reticulum specifically affects E-Cadherin expression and is required for gastrulation movements in Drosophila​
    Zhang, Y.; Kong, D. ; Reichl, L. ; Vogt, N.; Wolf, F.   & Großhans, J. ​ (2014) 
    Developmental Biology, 390(2) pp. 208​-220​.​ DOI: https://doi.org/10.1016/j.ydbio.2014.03.007 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​A computational model of nuclear self-organisation in syncytial embryos​
    Koke, C.; Kanesaki, T.; Grosshans, J. ; Schwarz, U. S. & Dunlop, C. M.​ (2014) 
    Journal of Theoretical Biology, 359 pp. 92​-100​.​ DOI: https://doi.org/10.1016/j.jtbi.2014.06.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Function and dynamics of slam in furrow formation in early Drosophila embryo​
    Acharya, S.; Laupsien, P.; Wenzl, C.; Yan, S. & Grosshans, J. ​ (2014) 
    Developmental Biology, 386(2) pp. 371​-384​.​ DOI: https://doi.org/10.1016/j.ydbio.2013.12.022 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy​
    Schulz, O.; Pieper, C. ; Clever, M.; Pfaff, J. ; Ruhlandt, A. ; Kehlenbach, R. H.   & Wouters, F. S.  et al.​ (2013) 
    Proceedings of the National Academy of Sciences of the United States of America, 110(52) pp. 21000​-21005​.​ DOI: https://doi.org/10.1073/pnas.1315858110 
    ​Details  DOI 
  • 2013 | Journal Article
    ​ ​Number of Nuclear Divisions in the Drosophila Blastoderm Controlled by Onset of Zygotic Transcription​
    Sung, H.-w.; Spangenberg, S.; Vogt, N. & Grosshans, J. ​ (2013) 
    Current Biology, 23(2) pp. 133​-138​.​ DOI: https://doi.org/10.1016/j.cub.2012.12.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Heterotrimeric G protein signaling governs the cortical stability during apical constriction in Drosophila gastrulation​
    Kanesaki, T.; Hirose, S.; Grosshans, J.   & Fuse, N.​ (2013) 
    Mechanisms of Development, 130(2-3) pp. 132​-142​.​ DOI: https://doi.org/10.1016/j.mod.2012.10.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​The F-BAR protein Cip4/Toca-1 antagonizes the formin Diaphanous in membrane stabilization and compartmentalization​
    Yan, S.; Lv, Z.; Winterhoff, M.; Wenzl, C.; Zobel, T.; Faix, J. & Bogdan, S. et al.​ (2013) 
    Journal of Cell Science, 126(8) pp. 1796​-1805​.​ DOI: https://doi.org/10.1242/jcs.118422 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Determining nuclear shape The role of farnesylated nuclear membrane proteins​
    Polychronidou, M. & Grosshans, J. ​ (2011) 
    NUCLEUS-AUSTIN, 2(1) pp. 17​-23​.​ DOI: https://doi.org/10.4161/nucl.2.1.13992 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​In Vivo Mapping of Hydrogen Peroxide and Oxidized Glutathione Reveals Chemical and Regional Specificity of Redox Homeostasis​
    Albrecht, S. C.; Barata, A. G.; Grosshans, J. ; Teleman, A. A. & Dick, T. P.​ (2011) 
    Cell Metabolism, 14(6) pp. 819​-829​.​ DOI: https://doi.org/10.1016/j.cmet.2011.10.010 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks​
    Kanesaki, T.; Edwards, C. M.; Schwarz, U. S. & Grosshans, J. ​ (2011) 
    Integrative Biology, 3(11) pp. 1112​-1119​.​ DOI: https://doi.org/10.1039/c1ib00059d 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Localization of RhoGEF2 during Drosophila cellularization is developmentally controlled by slam​
    Wenzl, C.; Yan, S. ; Laupsien, P. & Grosshans, J. ​ (2010) 
    Mechanisms of Development, 127(7-8) pp. 371​-384​.​ DOI: https://doi.org/10.1016/j.mod.2010.01.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Farnesylated Nuclear Proteins Kugelkern and Lamin Dm0 Affect Nuclear Morphology by Directly Interacting with the Nuclear Membrane​
    Polychronidou, M.; Hellwig, A. & Grosshans, J. ​ (2010) 
    Molecular Biology of the Cell, 21(19) pp. 3409​-3420​.​ DOI: https://doi.org/10.1091/mbc.E10-03-0230 
    ​Details  DOI  PMID  PMC  WoS 

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