Prof. Dr. Niels Voigt

 
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  • 2024 Lecture | 
    ​ ​Voigt N. ​„Herzbeben – Wenn das Herz außer Takt gerät…“​. ​Lecture presented at: Herz und Hirn - Gemeinsam im Fokus; ​2024-01-23; ​Göttingen. 
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  • 2023 Journal Article | 
    ​ ​Seibertz F, Sutanto H, Dülk R, Pronto JRD, Springer R, Rapedius M, et al. ​Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes​. ​​Basic Research in Cardiology. ​2023;​118​(1):​​14​. ​doi:10.1007/s00395-022-00973-0. 
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  • 2023 Journal Article
    ​ ​Grammatika Pavlidou N, Dobrev S, Beneke K, Reinhardt F, Pecha S, Jacquet E, et al. ​Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism​. ​​European Heart Journal. ​2023;. ​doi:10.1093/eurheartj/ehad086. 
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  • 2022 Journal Article | Overview | 
    ​ ​Rosholm KR, Badone B, Karatsiompani S, Nagy D, Seibertz F, Voigt N, et al. ​Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp​. ​​Frontiers in Molecular Neuroscience. ​2022;​15​. ​doi:10.3389/fnmol.2022.898717. 
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  • 2022 Journal Article | Research Paper | 
    ​ ​Jung P, Seibertz F, Fakuade FE, Ignatyeva N, Sampathkumar S, Ritter M, et al. ​Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy​. ​​Basic Research in Cardiology. ​2022;​117​(1):​​5​. ​doi:10.1007/s00395-022-00912-z. 
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  • 2022 Journal Article | Research Paper | 
    ​ ​Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R. ​A Mathematical Model for Electrical Activity in Pig Atrial Tissue​. ​​Frontiers in Physiology. ​2022;​13​. ​doi:10.3389/fphys.2022.812535. 
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  • 2022 Journal Article | Research Paper | 
    ​ ​Fakuade FE, Fauconnier J, Voigt N. ​Background calcium influx in arrhythmia: lead actor or extra?​. ​​The Journal of Physiology. ​2022;​600​(11):​​2545​-2546​. ​doi:10.1113/JP283032. 
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  • 2022 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Voigt N, Maack C, Pronto JRD. ​Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation​. ​​Journal of the American College of Cardiology. ​2022;​80​(23):​​2220​-2223​. ​doi:10.1016/j.jacc.2022.09.043. 
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  • 2022 Journal Article | 
    ​ ​Rapedius M, Obergrussberger A, Humphries ESA, Scholz S, Rinke-Weiss I, Goetze TA, et al. ​There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments​. ​​Frontiers in Molecular Neuroscience. ​2022;​15​. ​doi:10.3389/fnmol.2022.982316. 
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  • 2022 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Liutkute A, Brundel BJJM, Voigt N. ​Not the classical serendipity: does doxapram treat atrial fibrillation?​. ​​Cardiovascular Research. ​2022;. ​doi:10.1093/cvr/cvac044. 
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  • 2022 Journal Article | 
    ​ ​Seibertz F, Rapedius M, Fakuade FE, Tomsits P, Liutkute A, Cyganek L, et al. ​A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes​. ​​Communications Biology. ​2022;​5​(1). ​doi:10.1038/s42003-022-03871-2. 
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  • 2021 Preprint
    ​ ​Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R. ​A mathematical model for electrical activity in pig atrial tissue​. ​​2021. Available from: https://mbexc.uni-goettingen.de/literature/publications/416 doi: https://doi.org/10.1101/2021.10.18.464761​
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  • 2021 Journal Article
    ​ ​Trosclair K, Si M, Watts M, Gautier NM, Voigt N, Traylor J, et al. ​Kv1.1 potassium channel subunit deficiency alters ventricular arrhythmia susceptibility, contractility, and repolarization​. ​​Physiological Reports. ​2021;​9​(1). ​doi:10.14814/phy2.14702. 
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  • 2021 Journal Article
    ​ ​del Campo CV, Liaw NY, Gunadasa-Rohling M, Matthaei M, Braga L, Kennedy T, et al. ​Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer​. ​​Cardiovascular Research. ​2021;​118​(2):​​597​-611​. ​doi:10.1093/cvr/cvab054. 
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  • 2020 Journal Article | Overview
    ​ ​Schmidt C, Voigt N. ​Insights into cardiovascular research in Göttingen and Heidelberg: a report by the ESC Scientists of Tomorrow​. ​​Cardiovascular Research. ​2020;​116​(12):​​e162​-e164​. ​doi:10.1093/cvr/cvaa165. 
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  • 2020 Journal Article | Research Paper
    ​ ​Hofhuis J, Bersch K, Wagner S, Molina CE, Fakuade FE, Iyer LM, et al. ​Dysferlin links excitation-contraction coupling to structure and maintenance of the cardiac transverse-axial tubule system​. ​​Europace. ​2020;​22​(7):​​1119​-1131​. ​doi:10.1093/europace/euaa093. 
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  • 2020 Journal Article | Research Paper
    ​ ​Seibertz F, Reynolds M, Voigt N. ​Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes​. ​​Journal of Visualized Experiments. ​2020;(166). ​doi:10.3791/61890. 
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  • 2020 Journal Article | Research Paper
    ​ ​Tomsits P, Schüttler D, Kääb S, Clauss S, Voigt N. ​Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium Current​. ​​Journal of Visualized Experiments. ​2020;(165). ​doi:10.3791/61964. 
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  • 2020 Journal Article | Overview | 
    ​ ​Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N. ​Cellular and mitochondrial mechanisms of atrial fibrillation​. ​​Basic Research in Cardiology. ​2020;​115​(6). ​doi:10.1007/s00395-020-00827-7. 
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  • 2020 Journal Article | Research Paper
    ​ ​Reil J, Reil G, Kovács Á, Sequeira V, Waddingham MT, Lodi M, et al. ​CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect​. ​​The Journal of Physiology. ​2020;​598​(15):​​3129​-3153​. ​doi:10.1113/JP279607. 
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  • 2020 Journal Article
    ​ ​Fakuade FE, Steckmeister V, Seibertz F, Gronwald J, Kestel S, Menzel J, et al. ​Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation​. ​​Cardiovascular Research. ​2020;​117​(7):​​1790​-1801​. ​doi:10.1093/cvr/cvaa162. 
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  • 2020 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Fakuade FE, Tomsits P, Voigt N. ​Connexin hemichannels in atrial fibrillation: orphaned and irrelevant?​. ​​Cardiovascular Research. ​2020;​117​(1):​​4​-6​. ​doi:10.1093/cvr/cvaa308. 
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  • 2019 Conference Paper
    ​ ​Springer R, Seibertz F, Solano RA, Rubio T, Cyganek L, Zimmermann, Wolfram-Hubertus, et al. ​P1235Acetylcholine-activated inward-rectifier potassium currents in atrial cardiomyocytes derived from induced pluripotent stem cells and atrial engineered heart muscle preparations​. ​ ESC Congress 2019 together with World Congress of Cardiology; ​2019-08-31​ - 2019-09-04​; ​​Paris. ​European Heart Journal. ​2019;​40​(Suppl. 1)doi:10.1093/eurheartj/ehz748.0193.
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  • 2019 Journal Article | 
    ​ ​Voigt N, Ort K, Sossalla S. ​Arzneimittelinteraktionen, die man kennen muss!​. ​​Pneumologie. ​2019;​73​(05):​​306​-318​. ​doi:10.1055/a-0863-6242. 
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  • 2019 Journal Article | 
    ​ ​Voigt N, Ort K, Sossalla S. ​Arzneimittelinteraktionen, die man kennen muss!​. ​​Aktuelle Dermatologie. ​2019;​45​(04):​​179​-191​. ​doi:10.1055/a-0872-5993. 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Thomas D, Christ T, Fabritz L, Goette A, Hammwöhner M, Heijman J, et al. ​German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management​. ​​Clinical Research in Cardiology. ​2019;. ​doi:10.1007/s00392-018-1377-1. 
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  • 2019 Journal Article | Research Paper
    ​ ​Voigt N, Ort K, Sossalla S. ​Arzneimittelinteraktionen, die man kennen muss!​. ​​Deutsche medizinische Wochenschrift. ​2019;​144​(04):​​264​-275​. ​doi:10.1055/a-0160-8413. 
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  • 2019 Journal Article | Research Paper
    ​ ​Wiedmann F, Schlund D, Voigt N, Ratte A, Kraft M, Katus HA, et al. ​N-glycosylation–dependent regulation of hK 2P 17.1 currents​. ​​Molecular Biology of the Cell. ​2019;​30​(12):​​1425​-1436​. ​doi:10.1091/mbc.E18-10-0687. 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Voigt N, Ort K, Sossalla S. ​Arzneimittelinteraktionen, die man kennen muss!​. ​​Fortschritte der Neurologie · Psychiatrie. ​2019;​87​(05):​​320​-332​. ​doi:10.1055/a-0894-9924. 
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  • 2019 Journal Article | Interview
    ​ ​Voigt N, Sadoshima J. ​Scientists on the Spot: Autophagy and heart disease​. ​​Cardiovascular Research. ​2019;​115​(10):​​e91​-e92​. ​doi:10.1093/cvr/cvz124. 
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  • 2018 Research Data | Research Paper | 
    ​ ​Brandenburg S, Pawlowitz J, Lehnart SE, Fakuade FE, Kownatzki-Danger D, Kohl T, et al. ​Axial Tubule Junctions Activate Atrial Ca2+ Release across Species​. ​​2018. Available from: https://sfb1002.med.uni-goettingen.de/production/literature/publications/217 doi: https://doi.org/10.3389/fphys.2018.01227​
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  • 2018 Journal Article | Overview
    ​ ​Voigt N, Lehnart SE. ​Ryanodine receptor dysfunction and the resolution revolution: how Nobel Prize-winning techniques transform cardiovascular research​. ​​Cardiovascular Research. ​2018;​114​(14):​​e106​-e109​. ​doi:10.1093/cvr/cvy235. 
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  • 2018 Book Chapter
    ​ ​Heijman J, Molina CE, Voigt N. ​Voltage-Gated Calcium Channels and Their Roles in Cardiac Electrophysiology​. ​In: Thomas D, Remme CA​, editors. ​Channelopathies in Heart Disease. ​Cham: ​Springer; ​2018. p. 77​-96​. ​(Cardiac and Vascular Biology). doi:10.1007/978-3-319-77812-9_4. 
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  • 2018 Journal Article | Interview
    ​ ​Voigt N, Nattel S. ​Prof Niels Voigt talks to Prof Stanley Nattel about advances in atrial fibrillation research and career insights​. ​​Cardiovascular Research. ​2018;​114​(8):​​e65​. ​doi:10.1093/cvr/cvy142. 
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  • 2018 Journal Article
    ​ ​Heijman J, Kirchner D, Kunze F, Chrétien EM, Michel-Reher MB, Voigt N, et al. ​Muscarinic type-1 receptors contribute to I K,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation​. ​​International Journal of Cardiology. ​2018;​255​:​​61​-68​. ​doi:10.1016/j.ijcard.2017.12.050. 
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  • 2018 Journal Article
    ​ ​Voigt N, Mason F, Thomas D. ​Report on the Ion Channel Symposium Organized by the German Cardiac Society Working Group on Cellular Electrophysiology (AG 18)​. ​​Herzschrittmachertherapie + Elektrophysiologie. ​2018;​29​(1):​​4​-13​. ​doi:10.1007/s00399-017-0549-4. 
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  • 2018 Journal Article
    ​ ​Voigt N, Lederer . ​Niels Voigt talks to W. Jonathan Lederer, keynote lecturer at the “Göttingen Channels” Symposium 2017​. ​​Cardiovascular Research. ​2018;​114​(2):​​e14​-e14​. ​doi:10.1093/cvr/cvx241. 
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  • 2018 Journal Article | Research Paper
    ​ ​Wiedmann F, Schulte JS, Gomes B, Zafeiriou, Maria-Patapia, Ratte A, Rathjens F, et al. ​Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models: focus on TASK-1​. ​​Basic Research in Cardiology. ​2018;​113​(4):​​1​-14​. ​doi:10.1007/s00395-018-0687-9. 
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  • 2018 Journal Article | Research Paper
    ​ ​Schmidt C, Voigt N. ​ESC Congress 2018 highlights in basic science: a report from the Scientists of Tomorrow​. ​​Cardiovascular Research. ​2018;​114​(13):​​e103​-e105​. ​doi:10.1093/cvr/cvy234. 
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  • 2018 Journal Article | Research Paper
    ​ ​Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, et al. ​Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​. ​​Science Translational Medicine. ​2018;​10​(458). ​doi:10.1126/scitranslmed.aan0724. 
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  • 2017 Journal Article
    ​ ​Ji Y, Varkevisser R, Opacic D, Bossu A, Kuiper M, Beekman J, et al. ​The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models​. ​​British Journal of Pharmacology. ​2017;​174​(15):​​2576​-2590​. ​doi:10.1111/bph.13869. 
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  • 2017 Journal Article
    ​ ​Meyer T, Voigt N. ​In search for novel functions of adenosine 5′-triphosphate (ATP) in the heart​. ​​Cardiovascular Research. ​2017;​113​(14):​​e59​-e60​. ​doi:10.1093/cvr/cvx207. 
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  • 2017 Journal Article
    ​ ​Schmidt C, Wiedmann F, Zhou X, Heijman J, Voigt N, Ratte A, et al. ​Inverse remodelling of K(2P)3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy​. ​​European Heart Journal. ​2017;​38​(22):​​1764​-1774​. ​doi:10.1093/eurheartj/ehw559. 
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  • 2017 Journal Article | Letter Note
    ​ ​Molina CE, Voigt N. ​Finding Ms or Mr Right: Which miRNA to target in AF?​. ​​Journal of Molecular and Cellular Cardiology. ​2017;​102​:​​22​-25​. ​doi:10.1016/j.yjmcc.2016.11.007. 
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  • 2017 Journal Article | Research Paper
    ​ ​Schmidt C, Wiedmann F, Kallenberger SM, Ratte A, Schulte JS, Scholz B, et al. ​Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure​. ​​Progress in Biophysics and Molecular Biology. ​2017;​130​:​​233​-243​. ​doi:10.1016/j.pbiomolbio.2017.05.004. 
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  • 2017 Journal Article
    ​ ​Abu-Taha IH, Heijman J, Hippe, Hans-Jörg, Wolf NM, El-Armouche A, Nikolaev VO, et al. ​Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure​. ​​Circulation. ​2017;​135​(9):​​881​-897​. ​doi:10.1161/CIRCULATIONAHA.116.022852. 
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  • 2016 Journal Article
    ​ ​Smith SA, Hughes LD, Kline CF, Kempton AN, Dorn LE, Curran J, et al. ​Dysfunction of the β 2 -spectrin-based pathway in human heart failure​. ​​American Journal of Physiology-Heart and Circulatory Physiology. ​2016;​310​(11):​​H1583​-H1591​. ​doi:10.1152/ajpheart.00875.2015. 
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  • 2016 Journal Article
    ​ ​Schmidt C, Wiedmann F, Voigt N, Zhou, Xiao-Bo, Heijman J, Lang S, et al. ​Response to Letter Regarding Article, “Upregulation of K 2P 3.1 K + Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation”​. ​​Circulation. ​2016;​133​(11). ​doi:10.1161/CIRCULATIONAHA.115.020662. 
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  • 2016 Journal Article | Research Paper
    ​ ​Hartmann NH, Mason FE, Braun I, Pabel S, Voigt N, Schotola H, et al. ​The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology​. ​​Journal of Molecular and Cellular Cardiology. ​2016;​94​:​​95​-106​. ​doi:10.1016/j.yjmcc.2016.03.012. 
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  • 2015 Conference Abstract
    ​ ​Hartmann N, Mason F, Braun I, Voigt N, Fischer TH, Hasenfuß G, et al. ​The combined effects of ranolazine and low dose dronedarone on atrial vs. ventricular electrophysiology; a novel therapeutic hope?​. ​​London, ENGLAND. ​European Heart Journal. ​2015;​36​:1067​-1068​. ​
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  • 2015 Journal Article
    ​ ​Voigt N, Pearman CM, Dobrev D, Dibb KM. ​Methods for isolating atrial cells from large mammals and humans​. ​​Journal of Molecular and Cellular Cardiology. ​2015;​86​:​​187​-198​. ​doi:10.1016/j.yjmcc.2015.07.006. 
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  • 2015 Journal Article
    ​ ​Harada M, Tadevosyan A, Qi X, Xiao J, Liu T, Voigt N, et al. ​Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling​. ​​Journal of the American College of Cardiology. ​2015;​66​(1):​​47​-58​. ​doi:10.1016/j.jacc.2015.04.056. 
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  • 2015 Journal Article | Research Paper
    ​ ​Chiang DY, Lebesgue N, Beavers DL, Alsina KM, Damen JMA, Voigt N, et al. ​Alterations in the Interactome of Serine/Threonine Protein Phosphatase Type-1 in Atrial Fibrillation Patients​. ​​Journal of the American College of Cardiology. ​2015;​65​(2):​​163​-173​. ​doi:10.1016/j.jacc.2014.10.042. 
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  • 2015 Journal Article
    ​ ​Chiang DY, Zhang M, Voigt N, Alsina KM, Jakob H, Martin JF, et al. ​Identification of microRNA–mRNA dysregulations in paroxysmal atrial fibrillation​. ​​International Journal of Cardiology. ​2015;​184​:​​190​-197​. ​doi:10.1016/j.ijcard.2015.01.075. 
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  • 2015 Journal Article
    ​ ​Heijman J, Voigt N, Ghezelbash S, Schirmer I, Dobrev D. ​Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics​. ​​Journal of Cardiovascular Pharmacology. ​2015;​66​(6):​​515​-522​. ​doi:10.1097/FJC.0000000000000253. 
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  • 2015 Journal Article
    ​ ​Heijman J, Algalarrondo V, Voigt N, Melka J, Wehrens XH, Dobrev D, et al. ​The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis​. ​​Cardiovascular Research. ​2015;​109​(4):​​467​-479​. ​doi:10.1093/cvr/cvv275. 
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  • 2015 Journal Article
    ​ ​Glasscock E, Voigt N, McCauley MD, Sun Q, Li N, Chiang DY, et al. ​Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation​. ​​Basic Research in Cardiology. ​2015;​110​(5). ​doi:10.1007/s00395-015-0505-6. 
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  • 2015 Journal Article
    ​ ​Schmidt C, Wiedmann F, Voigt N, Zhou, Xiao-Bo, Heijman J, Lang S, et al. ​Upregulation of K 2P 3.1 K + Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation​. ​​Circulation. ​2015;​132​(2):​​82​-92​. ​doi:10.1161/CIRCULATIONAHA.114.012657. 
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  • 2015 Journal Article
    ​ ​Heijman J, Erfanian Abdoust P, Voigt N, Nattel S, Dobrev D. ​Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation​. ​​The Journal of Physiology. ​2015;​594​(3):​​537​-553​. ​doi:10.1113/JP271404. 
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  • 2014 Journal Article
    ​ ​Chiang DY, Kongchan N, Beavers DL, Alsina KM, Voigt N, Neilson JR, et al. ​Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium Release​. ​​Circulation: Arrhythmia and Electrophysiology. ​2014;​7​(6):​​1214​-1222​. ​doi:10.1161/CIRCEP.114.001973. 
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  • 2014 Journal Article
    ​ ​Ravens U, Katircioglu-Öztürk D, Wettwer E, Christ T, Dobrev D, Voigt N, et al. ​Application of the RIMARC algorithm to a large data set of action potentials and clinical parameters for risk prediction of atrial fibrillation​. ​​Medical & Biological Engineering & Computing. ​2014;​53​(3):​​263​-273​. ​doi:10.1007/s11517-014-1232-0. 
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  • 2014 Journal Article
    ​ ​Li N, Chiang DY, Voigt N, Martin JF, Dobrev D, Wehrens XH. ​GW25-e5168 Impaired Post-Transcriptional Regulation of RyR2 by microRNA-106b-25 Cluster Promotes Atrial Fibrillation​. ​​Journal of the American College of Cardiology. ​2014;​64​(16):​​C59​. ​doi:10.1016/j.jacc.2014.06.284. 
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  • 2014 Journal Article
    ​ ​Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, et al. ​Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation​. ​​Cardiovascular Research. ​2014;​103​(1):​​178​-187​. ​doi:10.1093/cvr/cvu123. 
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  • 2014 Journal Article
    ​ ​Heijman J, Voigt N, Wehrens XHT, Dobrev D. ​Calcium dysregulation in atrial fibrillation: the role of CaMKII​. ​​Frontiers in Pharmacology. ​2014;​5​. ​doi:10.3389/fphar.2014.00030. 
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  • 2014 Journal Article
    ​ ​Heijman J, Voigt N, Carlsson L, Dobrev D. ​Cardiac safety assays​. ​​Current Opinion in Pharmacology. ​2014;​15​:​​16​-21​. ​doi:10.1016/j.coph.2013.11.004. 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Greiser M, Kerfant, Benoît-Gilles, Williams GS, Voigt N, Harks E, Dibb KM, et al. ​Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes​. ​​Journal of Clinical Investigation. ​2014;​124​(11):​​4759​-4772​. ​doi:10.1172/JCI70102. 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Heijman J, Voigt N, Nattel S, Dobrev D. ​Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression​. ​​Circulation Research. ​2014;​114​(9):​​1483​-1499​. ​doi:10.1161/CIRCRESAHA.114.302226. 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, et al. ​Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model​. ​​Circulation. ​2014;​129​(12):​​1276​-1285​. ​doi:10.1161/CIRCULATIONAHA.113.006611. 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Voigt N, Heijman J, Wang Q, Chiang DY, Li N, Karck M, et al. ​Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation​. ​​Circulation. ​2014;​129​(2):​​145​-156​. ​doi:10.1161/CIRCULATIONAHA.113.006641. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, et al. ​Mutation E169K in Junctophilin-2 Causes Atrial Fibrillation Due to Impaired RyR2 Stabilization​. ​​Journal of the American College of Cardiology. ​2013;​62​(21):​​2010​-2019​. ​doi:10.1016/j.jacc.2013.06.052. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Heijman J, Voigt N, Abu-Taha IH, Dobrev D. ​Rhythm Control of Atrial Fibrillation in Heart Failure​. ​​Heart Failure Clinics. ​2013;​9​(4):​​407​-415​. ​doi:10.1016/j.hfc.2013.06.001. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Levay M, Krobert KA, Wittig K, Voigt N, Bermudez M, Wolber G, et al. ​NSC23766, a Widely Used Inhibitor of Rac1 Activation, Additionally Acts as a Competitive Antagonist at Muscarinic Acetylcholine Receptors​. ​​Journal of Pharmacology and Experimental Therapeutics. ​2013;​347​(1):​​69​-79​. ​doi:10.1124/jpet.113.207266. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Voigt N, Zhou, Xiao-Bo, Dobrev D. ​Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents​. ​​Journal of Visualized Experiments. ​2013;(77). ​doi:10.3791/50235. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Voigt N, Heijman J, Trausch A, Mintert-Jancke E, Pott L, Ravens U, et al. ​Impaired Na+-dependent regulation of acetylcholine-activated inward-rectifier K+ current modulates action potential rate dependence in patients with chronic atrial fibrillation​. ​​Journal of Molecular and Cellular Cardiology. ​2013;​61​:​​142​-152​. ​doi:10.1016/j.yjmcc.2013.03.011. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Voigt N, Dobrev D. ​The biology of human pulmonary veins: Does it help us to better understand AF pathophysiology in patients?​. ​​Heart Rhythm. ​2013;​10​(3):​​392​-393​. ​doi:10.1016/j.hrthm.2012.12.010. 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Dawson K, Wakili R, Ördög B, Clauss S, Chen Y, Iwasaki Y, et al. ​MicroRNA29​. ​​Circulation. ​2013;​127​(14):​​1466​-1475​. ​doi:10.1161/CIRCULATIONAHA.112.001207. 
    Details  DOI 
  • 2013 Journal Article | Research Paper
    ​ ​Purohit A, Rokita AG, Guan X, Chen B, Koval OM, Voigt N, et al. ​Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation​. ​​Circulation. ​2013;​128​(16):​​1748​-1757​. ​doi:10.1161/CIRCULATIONAHA.113.003313. 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article
    ​ ​Respress JL, van Oort RJ, Li N, Rolim N, Dixit SS, deAlmeida A, et al. ​Role of RyR2 Phosphorylation at S2814 During Heart Failure Progression​. ​​Circulation Research. ​2012;​110​(11):​​1474​-1483​. ​doi:10.1161/CIRCRESAHA.112.268094. 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Harada M, Luo X, Qi XY, Tadevosyan A, Maguy A, Ordog B, et al. ​Transient Receptor Potential Canonical-3 Channel–Dependent Fibroblast Regulation in Atrial Fibrillation​. ​​Circulation. ​2012;​126​(17):​​2051​-2064​. ​doi:10.1161/CIRCULATIONAHA.112.121830. 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, et al. ​Enhanced Sarcoplasmic Reticulum Ca 2+ Leak and Increased Na + -Ca 2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation​. ​​Circulation. ​2012;​125​(17):​​2059​-2070​. ​doi:10.1161/CIRCULATIONAHA.111.067306. 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Li N, Wang T, Wang W, Cutler MJ, Wang Q, Voigt N, et al. ​Inhibition of CaMKII Phosphorylation of RyR2 Prevents Induction of Atrial Fibrillation in FKBP12.6 Knockout Mice​. ​​Circulation Research. ​2012;​110​(3):​​465​-470​. ​doi:10.1161/CIRCRESAHA.111.253229. 
    Details  DOI 
  • 2012 Book Chapter
    ​ ​Voigt N, Nattel S, Dobrev D. ​Proarrhythmic Atrial Calcium Cycling in the Diseased Heart​. ​In: Islam MS​, editor. ​Calcium Signaling. ​Dordrecht: ​Springer Netherlands; ​2012. p. 1175​-1191​. ​doi:10.1007/978-94-007-2888-2_53. 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Voigt N, Dobrev D. ​Cellular and molecular correlates of ectopic activity in patients with atrial fibrillation​. ​​Europace. ​2012;​14​(suppl 5):​​v97​-v105​. ​doi:10.1093/europace/eus282. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Makary S, Voigt N, Maguy A, Wakili R, Nishida K, Harada M, et al. ​Differential Protein Kinase C Isoform Regulation and Increased Constitutive Activity of Acetylcholine-Regulated Potassium Channels in Atrial Remodeling​. ​​Circulation Research. ​2011;​109​(9):​​1031​-1043​. ​doi:10.1161/CIRCRESAHA.111.253120. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, et al. ​Oxidized CaMKII causes cardiac sinus node dysfunction in mice​. ​​Journal of Clinical Investigation. ​2011;​121​(8):​​3277​-3288​. ​doi:10.1172/JCI57833. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Wakili R, Voigt N, Kääb S, Dobrev D, Nattel S. ​Recent advances in the molecular pathophysiology of atrial fibrillation​. ​​Journal of Clinical Investigation. ​2011;​121​(8):​​2955​-2968​. ​doi:10.1172/JCI46315. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, et al. ​Defects in Ankyrin-Based Membrane Protein Targeting Pathways Underlie Atrial Fibrillation​. ​​Circulation. ​2011;​124​(11):​​1212​-1222​. ​doi:10.1161/CIRCULATIONAHA.111.023986. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Grandi E, Pandit SV, Voigt N, Workman AJ, Dobrev D, Jalife J, et al. ​Human Atrial Action Potential and Ca 2+ Model​. ​​Circulation Research. ​2011;​109​(9):​​1055​-1066​. ​doi:10.1161/CIRCRESAHA.111.253955. 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Tsuji Y, Hojo M, Voigt N, El-Armouche A, Inden Y, Murohara T, et al. ​Ca2+-Related Signaling and Protein Phosphorylation Abnormalities Play Central Roles in a New Experimental Model of Electrical Storm​. ​​Circulation. ​2011;​123​(20):​​2192​-U67​. ​doi:10.1161/CIRCULATIONAHA.110.016683. 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article
    ​ ​Wakili R, Yeh, Yung-Hsin, Yan Qi X, Greiser M, Chartier D, Nishida K, et al. ​Multiple Potential Molecular Contributors to Atrial Hypocontractility Caused by Atrial Tachycardia Remodeling in Dogs​. ​​Circulation: Arrhythmia and Electrophysiology. ​2010;​3​(5):​​530​-541​. ​doi:10.1161/CIRCEP.109.933036. 
    Details  DOI 
  • 2010 Journal Article
    ​ ​Voigt N, Trausch A, Knaut M, Matschke K, Varró A, Van Wagoner DR, et al. ​Left-to-Right Atrial Inward Rectifier Potassium Current Gradients in Patients With Paroxysmal Versus Chronic Atrial Fibrillation​. ​​Circulation: Arrhythmia and Electrophysiology. ​2010;​3​(5):​​472​-480​. ​doi:10.1161/CIRCEP.110.954636. 
    Details  DOI 
  • 2010 Journal Article
    ​ ​Dobrev D, Voigt N, Wehrens XHT. ​The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications​. ​​Cardiovascular Research. ​2010;​89​(4):​​734​-743​. ​doi:10.1093/cvr/cvq324. 
    Details  DOI 
  • 2010 Book Chapter
    ​ ​Voigt N, Makary S, Nattel S, Dobrev D. ​Voltage-clamp-based methods for the detection of constitutively active acetylcholine-gated I(K,ACh) channels in the diseased heart​. ​In: Conn PM​, editor. ​Constitutive Activity in Receptors and Other Proteins, Part A. ​Elsevier; ​2010. p. 653​-675​. ​doi:10.1016/B978-0-12-381298-8.00032-0. 
    Details  DOI  PMID  PMC 
  • 2009 Journal Article
    ​ ​Voigt N, Rozmaritsa N, Trausch A, Zimniak T, Christ T, Wettwer E, et al. ​Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation​. ​​Naunyn-Schmiedeberg's Archives of Pharmacology. ​2009;​381​(3):​​251​-259​. ​doi:10.1007/s00210-009-0452-6. 
    Details  DOI 
  • 2007 Journal Article
    ​ ​Voigt N, FRIEDRICH A, BOCK M, WETTWER E, CHRIST T, KNAUT M, et al. ​Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation​. ​​Cardiovascular Research. ​2007;​74​(3):​​426​-437​. ​doi:10.1016/j.cardiores.2007.02.009. 
    Details  DOI 
  • 2007 Journal Article
    ​ ​Voigt N, Maguy A, Yeh, Y.-H., Qi X, Ravens U, Dobrev D, et al. ​Changes in IK,ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes​. ​​Cardiovascular Research. ​2007;​77​(1):​​35​-43​. ​doi:10.1093/cvr/cvm051. 
    Details  DOI 

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