Prof. Dr. med. Jochen Gaedcke

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  • 2023 | Journal Article | 
    ​ ​Incidence and impact of new-onset postoperative arrhythmia after surgery of the lower gastrointestinal tract​
    Rühlmann, F.; Hedicke, M. S.; Engelhardt, D.; Mackert, A. F.; Tichelbäcker, T.; Leha, A. & Bernhardt, M. et al.​ (2023) 
    Scientific Reports, 13(1).​ DOI: https://doi.org/10.1038/s41598-023-27508-4 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Enhancer of Zeste Homolog 2 (EZH2) Is a Marker of High-Grade Neuroendocrine Neoplasia in Gastroenteropancreatic and Pulmonary Tract and Predicts Poor Prognosis​
    Bremer, S. C. B. ; Bittner, G.; Elakad, O.; Dinter, H.; Gaedcke, J. ; König, A. O.   & Amanzada, A.  et al.​ (2022) 
    Cancers, 14(12) pp. 2828​.​ DOI: https://doi.org/10.3390/cancers14122828 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo​
    De Oliveira, T.; Goldhardt, T.; Edelmann, M.; Rogge, T. ; Rauch, K. ; Kyuchukov, N. D. & Menck, K.  et al.​ (2021) 
    Cancers, 13(5) pp. 1011​.​ DOI: https://doi.org/10.3390/cancers13051011 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy​
    Koerdel, K.; Spitzner, M. ; Meyer, T. ; Engels, N.; Krause, F.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2021) 
    Cancers, 13(3) pp. 455​.​ DOI: https://doi.org/10.3390/cancers13030455 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​CA19-9 for detecting recurrence of pancreatic cancer​
    Azizian, A. ; Rühlmann, F. ; Krause, T.; Bernhardt, M. ; Jo, P. ; König, A.   & Kleiß, M. et al.​ (2020) 
    Scientific Reports, 10(1).​ DOI: https://doi.org/10.1038/s41598-020-57930-x 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer​
    Jo, P. ; Bernhardt, M. ; Nietert, M. ; König, A. ; Azizian, A. ; Schirmer, M. A.   & Grade, M.  et al.​ (2020) 
    PLoS One, 15(10) pp. e0239806​.​ DOI: https://doi.org/10.1371/journal.pone.0239806 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells​
    Sen, M. ; Wang, X.; Hamdan, F. H. ; Rapp, J.; Eggert, J.; Kosinsky, R. L.   & Wegwitz, F.  et al.​ (2019) 
    Clinical Epigenetics, 11(1).​ DOI: https://doi.org/10.1186/s13148-019-0690-5 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer​
    Flebbe, H.; Hamdan, F. H. ; Kari, V. ; Kitz, J. ; Gaedcke, J. ; Ghadimi, B. M. & Johnsen, S. A.  et al.​ (2019) 
    Cancers, 11(8) art. 1142​.​ DOI: https://doi.org/10.3390/cancers11081142 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells.​
    Wolff, A. ; Bayerlová, M. ; Gaedcke, J. ; Kube, D.   & Beißbarth, T. ​ (2018) 
    PLOS ONE, 13(5) art. e0197162​.​ DOI: https://doi.org/10.1371/journal.pone.0197162 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper | 
    ​ ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​
    Jo, P. ; Azizian, A. ; Salendo, J. ; Kramer, F. ; Bernhardt, M. ; Wolff, H. A.   & Gruber, J. et al.​ (2017) 
    International Journal of Molecular Sciences, 18(6) art. 1140​.​ DOI: https://doi.org/10.3390/ijms18061140 
    ​Details  DOI  WoS 
  • 2016 | Journal Article | 
    ​ ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​
    Jo, P. ; Nietert, M. M. ; Gusky, L.; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016) 
    Scientific Reports, 6 art. 35589​.​ DOI: https://doi.org/10.1038/srep35589 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.​
    Srinivas, U. S.; Dyczkowski, J.; Beißbarth, T. ; Gaedcke, J. ; Mansour, W. Y.; Borgmann, K. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(14) pp. 12574​-12586​.​ DOI: https://doi.org/10.18632/oncotarget.3728 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair​
    Wu, Y.; Lee, S.-H.; Williamson, E. A.; Reinert, B. L.; Cho, J. H.; Xia, F. & Jaiswal, A. S. et al.​ (2015) 
    PLoS Genetics, 11(12) art. e1005675​.​ DOI: https://doi.org/10.1371/journal.pgen.1005675 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib​
    Landmann, H.; Proia, D. A.; He, S.; Ogden, F. L.; Kramer, F.-J. ; Beißbarth, T.   & Grade, M.  et al.​ (2014) 
    Cell Death and Disease, 5 art. e1411​.​ DOI: https://doi.org/10.1038/cddis.2014.378 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​A GENE EXPRESSION SIGNATURE FOR CHEMORADIOSENSITIVITY OF COLORECTAL CANCER CELLS​
    Spitzner, M. ; Emons, G. ; Kramer, F. ; Gaedcke, J. ; Rave-Fränk, M. ; Scharf, J.-G. & Burfeind, P.  et al.​ (2010) 
    International Journal of Radiation Oncology*Biology*Physics, 78(4) pp. 1184​-1192​.​ DOI: https://doi.org/10.1016/j.ijrobp.2010.06.023 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Impact of RNA degradation on gene expression profiling​
    Opitz, L. ; Salinas-Riester, G. ; Grade, M. ; Jung, K. ; Jo, P. ; Emons, G.   & Ghadimi, M. B.  et al.​ (2010) 
    BMC Medical Genomics, 3 art. 36​.​ DOI: https://doi.org/10.1186/1755-8794-3-36 
    ​Details  DOI  PMID  PMC  WoS 

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