Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)

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  • 2023 | Journal Article | 
    ​ ​Brainstem atrophy in dementia with Lewy bodies compared with progressive supranuclear palsy and Parkinson’s disease on MRI​
    Müller, S. J.; Khadhraoui, E.; Hansen, N.; Jamous, A.; Langer, P.; Wiltfang, J. & Riedel, C. H. et al.​ (2023) 
    BMC Neurology, 23(1) art. 114​.​ DOI: https://doi.org/10.1186/s12883-023-03151-4 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies​
    Schmitz, M. ; Candelise, N.; Canaslan, S.; Altmeppen, H. C.; Matschke, J.; Glatzel, M. & Younas, N. et al.​ (2023) 
    Translational Neurodegeneration, 12(1) art. 12​.​ DOI: https://doi.org/10.1186/s40035-023-00342-4 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Exploring the ATN classification system using brain morphology​
    Heinzinger, N.; Maass, A.; Berron, D.; Yakupov, R.; Peters, O.; Fiebach, J. & Villringer, K. et al.​ (2023) 
    Alzheimer's Research & Therapy, 15(1) art. 50​.​ DOI: https://doi.org/10.1186/s13195-023-01185-x 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Brain reserve contributes to distinguishing preclinical Alzheimer’s stages 1 and 2​
    Yildirim, Z.; Delen, F.; Berron, D.; Baumeister, H.; Ziegler, G.; Schütze, H. & Glanz, W. et al.​ (2023) 
    Alzheimer's Research & Therapy, 15(1) art. 43​.​ DOI: https://doi.org/10.1186/s13195-023-01187-9 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation​
    Klafki, H.-W. ; Vogelgsang, J.; Manuilova, E.; Bauer, C.; Jethwa, A.; Esselmann, H.   & Jahn-Brodmann, A. et al.​ (2022) 
    Alzheimer's Research & Therapy, 14(1) art. 127​.​ DOI: https://doi.org/10.1186/s13195-022-01071-y 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs​
    Babu, M.; Favretto, F. ; Rankovic, M. & Zweckstetter, M. ​ (2022) 
    Journal of the American Chemical Society, art. jacs.2c07149​.​ DOI: https://doi.org/10.1021/jacs.2c07149 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Blutbasierte Biomarker zur Optimierung der Früh- und Differentialdiagnostik der Alzheimer-Demenz​
    Hansen, N.; Rauter, C. & Wiltfang, J. ​ (2022) 
    Fortschritte der Neurologie · Psychiatrie, 90(07/08) pp. 326​-335​.​ DOI: https://doi.org/10.1055/a-1839-6237 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​A Comparison of Operational Definitions for Mild Cognitive Impairment​
    Polcher, A.; Wolfsgruber, S.; Peters, O.; Frölich, L.; Wiltfang, J. ; Kornhuber, J.   & Hüll, M. et al.​ (2022) 
    Journal of Alzheimer's Disease, 88(4) pp. 1663​-1678​.​ DOI: https://doi.org/10.3233/JAD-215548 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Molecular interactions of FG nucleoporin repeats at high resolution​
    Ibáñez de Opakua, A.; Geraets, J. A.; Frieg, B.; Dienemann, C. ; Savastano, A. ; Rankovic, M. & Cima-Omori, M.-S. et al.​ (2022) 
    Nature Chemistry,.​ DOI: https://doi.org/10.1038/s41557-022-01035-7 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults​
    Böttcher, A.; Zarucha, A.; Köbe, T.; Gaubert, M.; Höppner, A.; Altenstein, S. & Bartels, C.  et al.​ (2022) 
    Frontiers in Psychology, 13 art. 945709​.​ DOI: https://doi.org/10.3389/fpsyg.2022.945709 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding​
    Sang, D.; Shu, T.; Pantoja, C. F.; Ibáñez de Opakua, A.; Zweckstetter, M.   & Holt, L. J.​ (2022) 
    Molecular Cell,.​ DOI: https://doi.org/10.1016/j.molcel.2022.08.016 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Relationship of serum beta‐synuclein with blood biomarkers and brain atrophy​
    Oeckl, P.; Anderl‐Straub, S.; Danek, A.; Diehl‐Schmid, J.; Fassbender, K.; Fliessbach, K. & Halbgebauer, S. et al.​ (2022) 
    Alzheimer's & Dementia, art. alz.12790​.​ DOI: https://doi.org/10.1002/alz.12790 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation​
    Zachrdla, M.; Savastano, A. ; Ibáñez de Opakua, A.; Cima‐Omori, M. & Zweckstetter, M. ​ (2022) 
    Protein Science, 31(9).​ DOI: https://doi.org/10.1002/pro.4409 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein​
    Frieg, B.; Geraets, J. A.; Strohäker, T.; Dienemann, C. ; Mavroeidi, P.; Jung, B. C. & Kim, W. S. et al.​ (2022) 
    Communications Biology, 5(1).​ DOI: https://doi.org/10.1038/s42003-022-03948-y 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Phase separation of the microtubule-associated protein tau​
    Chakraborty, P. & Zweckstetter, M. ​ (2022) 
    Essays in Biochemistry, art. EBC20220066​.​ DOI: https://doi.org/10.1042/EBC20220066 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers​
    Jansen, I. E.; van der Lee, S. J.; Gomez-Fonseca, D.; de Rojas, I.; Dalmasso, M. C.; Grenier-Boley, B. & Zettergren, A. et al.​ (2022) 
    Acta Neuropathologica,.​ DOI: https://doi.org/10.1007/s00401-022-02454-z 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Psychophysics and computational modeling of feature-continuous motion perception​
    Töpfer, F. M.; Barbieri, R.; Sexton, C. M.; Wang, X.; Soch, J.; Bogler, C. & Haynes, J.-D.​ (2022) 
    Journal of Vision, 22(11) pp. 16​.​ DOI: https://doi.org/10.1167/jov.22.11.16 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​The use of alfaxalone for short-term anesthesia can confound serum progesterone measurements in the common marmoset: a case report​
    Daskalaki, M.; Drummer, C. ; Behr, R.   & Heistermann, M. ​ (2022) 
    Primate Biology, 9(2) pp. 23​-28​.​ DOI: https://doi.org/10.5194/pb-9-23-2022 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia​
    Kleineidam, L.; Wagner, M.; Guski, J.; Wolfsgruber, S.; Miebach, L.; Bickel, H. & König, H. et al.​ (2022) 
    Alzheimer's & Dementia, art. alz.12785​.​ DOI: https://doi.org/10.1002/alz.12785 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity​
    Brás, I. C.; Khani, M. H. ; Vasili, E.; Möbius, W. ; Riedel, D. ; Parfentev, I. & Gerhardt, E.  et al.​ (2022) 
    Journal of Parkinson's Disease, pp. 1​-26​.​ DOI: https://doi.org/10.3233/JPD-223516 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms​
    Shvachiy, L.; Amaro-Leal, Â.; Outeiro, T. F. ; Rocha, I. & Geraldes, V.​ (2022) 
    Biology, 11(8) pp. 1164​.​ DOI: https://doi.org/10.3390/biology11081164 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Structures for the care of people with dementia: a European comparison​
    Schmachtenberg, T.; Monsees, J. & Thyrian, J. R.​ (2022) 
    BMC Health Services Research, 22(1) pp. 1372​.​ DOI: https://doi.org/10.1186/s12913-022-08715-7 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies​
    Koss, D. J.; Erskine, D.; Porter, A.; Palmoski, P.; Menon, H.; Todd, O. G. J. & Leite, M. et al.​ (2022) 
    Acta Neuropathologica Communications, 10(1).​ DOI: https://doi.org/10.1186/s40478-022-01403-x 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Preserved visuoconstruction in patients with Alzheimer's pathology and anti-neural autoantibodies: A case control study​
    Hansen, N.; Hirschel, S.; Teegen, B.; Wiltfang, J. & Malchow, B.​ (2022) 
    Frontiers in Dementia, 1.​ DOI: https://doi.org/10.3389/frdem.2022.975851 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Biomarkers of neurodegeneration in neural autoantibody-associated psychiatric syndromes: A retrospective cohort study​
    Juhl, A. L.; Grenzer, I. M.; Teegen, B.; Wiltfang, J. ; Fitzner, D. & Hansen, N.​ (2022) 
    Journal of translational autoimmunity, 5 art. 100169​.​ DOI: https://doi.org/10.1016/j.jtauto.2022.100169 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​One year of digital teaching in psychiatry as a response to the COVID-19 pandemic: Knowledge gain and content evaluation of medical students for two summer semesters in 2020 and 2021​
    Besse, M. ; Signerski-Krieger, J. ; Wiltfang, J. ; Bartels, C.   & Belz, M. ​ (2022) 
    PLOS ONE, 17(10) art. e0276660​.​ DOI: https://doi.org/10.1371/journal.pone.0276660 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Dental Care of Patients With Dementia: A Survey on Practice Equipment, Training, and Dental Treatment​
    Schaper, S.; Meyer-Rötz, S. H. ; Bartels, C. ; Wiltfang, J. ; Rödig, T. ; Schott, B. H. & Belz, M. ​ (2021) 
    Frontiers in oral health, 2 pp. 682139​.​ DOI: https://doi.org/10.3389/froh.2021.682139 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Oxidative stress in drug-naïve first episode patients with schizophrenia and major depression: ​effects of disease acuity and potential confounders​
    Jordan, W. ; Dobrowolny, H.; Bahn, S.; Bernstein, H.-G.; Brigadski, T.; Frodl, T. & Isermann, B. et al.​ (2018) 
    European Archives of Psychiatry and Clinical Neuroscience, 268(2) pp. 129​-143​.​ DOI: https://doi.org/10.1007/s00406-016-0749-7 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia​
    Hüttenrauch, M.; Ogorek, I.; Klafki, H.; Otto, M.; Stadelmann, C. ; Weggen, S. & Wiltfang, J. et al.​ (2018) 
    Acta Neuropathologica Communications, 6(1) art. 108​.​ DOI: https://doi.org/10.1186/s40478-018-0612-3 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity​
    Tolö, J.; Taschenberger, G.; Leite, K.; Stahlberg, M. A.; Spehlbrink, G.; Kues, J. & Munari, F. et al.​ (2018) 
    Frontiers in Molecular Neuroscience, 11 art. 49​.​ DOI: https://doi.org/10.3389/fnmol.2018.00049 
    ​Details  DOI 
  • 2018 | Journal Article | Overview | 
    ​ ​Circulating miRNAs as Diagnostic Biomarkers for Parkinson’s Disease​
    Roser, A.-E. ; Caldi Gomes, L.; Schünemann, J.; Maass, F.   & Lingor, P. ​ (2018) 
    Frontiers in Neuroscience, 12 art. 625​.​ DOI: https://doi.org/10.3389/fnins.2018.00625 
    ​Details  DOI  arXiv 
  • 2018 | Journal Article | 
    ​ ​A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease​
    Shahpasand-Kroner, H.; Klafki, H.-W.; Bauer, C.; Schuchhardt, J.; Hüttenrauch, M.; Stazi, M. & Bouter, C. et al.​ (2018) 
    Alzheimer's Research & Therapy, 10(1) art. 121​.​ DOI: https://doi.org/10.1186/s13195-018-0448-x 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Bacterial infections among patients with psychiatric disorders: Relation with hospital stay, age, and psychiatric diagnoses​
    Belz, M.; Rehling, N.; Schmidt, U.; Wiltfang, J.; Kis, B. & Wolff-Menzler, C.​ (2018) 
    PLOS ONE, 13(12) art. e0208458​.​ DOI: https://doi.org/10.1371/journal.pone.0208458 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain​
    Mandad, S.; Rahman, R.-U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B. & Keihani, S. et al.​ (2018) 
    Scientific Reports, 8(1) art. 16913​.​ DOI: https://doi.org/10.1038/s41598-018-35277-8 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus​
    Weise, S. C.; Arumugam, G.; Villarreal, A.; Videm, P.; Heidrich, S.; Nebel, N. & Dumit, V. I. et al.​ (2018) 
    Molecular Neurobiology, pp. 1​-14​.​ DOI: https://doi.org/10.1007/s12035-018-1444-7 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex​
    Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C.-T.; Pérez-Lara, Á.; Chakraborty, P. & Hofele, R. V. et al.​ (2018) 
    Nature Communications, 9(1) art. 4532​.​ DOI: https://doi.org/10.1038/s41467-018-06880-0 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.​
    Fornasiero, E. F.; Mandad, S.; Wildhagen, H.; Alevra, M.; Rammner, B.; Keihani, S. & Opazo, F. et al.​ (2018) 
    Nature Communications, 9(1) art. 4230​.​ DOI: https://doi.org/10.1038/s41467-018-06519-0 
    ​Details  DOI  PMID  PMC 

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