Dr. med. Nils Teucher

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  • 2015 Journal Article | Research Paper
    ​ ​Negative Hemodynamic Effects of Pantoprazole at High Infusion Rates in Mice​
    Unsoeld, B. W.; Teucher, N. ; Didie, M. ; Sossalla, S. ; Jacobshagen, C. ; Seidler, T.   & Schillinger, W.  et al.​ (2015) 
    Cardiovascular Therapeutics33(1) pp. 20​-26​.​ DOI: https://doi.org/10.1111/1755-5922.12102 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure​
    Buyandelger, B.; Mansfield, C.; Kostin, S.; Choi, O.; Roberts, A. M.; Ware, J. S. & Mazzarotto, F. et al.​ (2015) 
    Circulation: Cardiovascular Genetics8(5) pp. 643​-652​.​ DOI: https://doi.org/10.1161/CIRCGENETICS.113.000690 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Conference Abstract
    ​ ​CAMKII IN THE TRANSITION FROM PRESSURE-OVERLOAD CARDIAC HYPERTROPHY TOWARDS HEART FAILURE IN THE MOUSE​
    Rokita, A. G.; Mark, A. E.; Schmidt, K.; Sowa, T.; Maier, L. S. & Teucher, N. ​ (2012)
    Journal of Investigative Medicine60(4) ​Joint Annual Meeting of the Central-Society-for-Clinical-Research (CSCR) and Midwestern Section American Federation for Medical Research (MSAFMR)​, Chicago, IL.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​The risk-to-benefit ratio of transcatheter aortic valve implantation in specific patient cohorts: a single-centre experience​
    Puls, M. ; Viel, T.; Danner, B. C. ; Jacobshagen, C. ; Teucher, N. ; Hanekop, G. & Schoendube, F.  et al.​ (2012) 
    Clinical Research in Cardiology101(7) pp. 553​-563​.​ DOI: https://doi.org/10.1007/s00392-012-0426-4 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​Limitations of FKBP12.6-directed treatment strategies for maladaptive cardiac remodeling and heart failure​
    Seidler, T. ; Teucher, N. ; Hellenkamp, K. ; Unsoeld, B. W.; Grebe, C.; Kramps, P. & Schotola, H. et al.​ (2011) 
    Journal of Molecular and Cellular Cardiology50(1) pp. 33​-42​.​ DOI: https://doi.org/10.1016/j.yjmcc.2010.08.016 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart​
    Knöll, R.; Linke, W. A. ; Zou, P.; Miocic, S.; Kostin, S.; Buyandelger, B. & Ku, C.-H. et al.​ (2011) 
    Circulation Research109(7) pp. 758​-U153​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.111.245787 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper | 
    ​ ​Differential Cardiac Remodeling in Preload Versus Afterload​
    Toischer, K. ; Rokita, A. G.; Unsoeld, B. W.; Zhu, W.; Kararigas, G.; Sossalla, S.   & Reuter, S. P. et al.​ (2010) 
    Circulation122(10) pp. 993​-1003​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.110.943431 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper | 
    ​ ​BNP controls early load-dependent regulation of SERCA through calcineurin​
    Toischer, K. ; Teucher, N. ; Unsoeld, B. W.; Kuhn, M.; Koegler, H. & Hasenfuß, G. ​ (2010) 
    Basic Research in Cardiology105(6) pp. 795​-804​.​ DOI: https://doi.org/10.1007/s00395-010-0115-2 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper | 
    ​ ​High Precision Quantitative Proteomics Using iTRAQ on an LTQ Orbitrap: A New Mass Spectrometric Method Combining the Benefits of All​
    Koecher, T.; Pichler, P.; Schutzbier, M.; Stingl, C.; Kaul, A.; Teucher, N.   & Hasenfuß, G.  et al.​ (2009) 
    Journal of Proteome Research8(10) pp. 4743​-4752​.​ DOI: https://doi.org/10.1021/pr900451u 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper | 
    ​ ​Recent in vitro findings of negative inotropy of pantoprazole did not translate into clinically relevant effects on left ventricular function in healthy volunteers​
    Schillinger, W. ; Hoernes, N.; Teucher, N. ; Sossalla, S. ; Sehrt, D.; Jung, K.   & Huenlich, M.  et al.​ (2009) 
    Clinical Research in Cardiology98(6) pp. 391​-399​.​ DOI: https://doi.org/10.1007/s00392-009-0012-6 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Conference Abstract
    ​ ​CaMKII prolongs action potential duration in pressure overload induced hypertrophy​
    Gupta, S. N.; Rokita, A. G.; Schmidt, K.; Unsoeld, B. W.; Teucher, N. ; Sowa, T. & Sag, C. M. et al.​ (2008)
    European Heart Journal29 
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Celecoxib modulates hypertrophic signalling and prevents load-induced cardiac dysfunction​
    Jacobshagen, C. ; Grueber, M.; Teucher, N. ; Schmidt, A. G.; Unsoeld, B. W.; Toischer, K.   & Van, P. N. et al.​ (2008) 
    European Journal of Heart Failure10(4) pp. 334​-342​.​ DOI: https://doi.org/10.1016/j.ejheart.2008.02.013 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Conference Abstract
    ​ ​Inhibited phosphorylation of PTEN attenuates the transition from cardiac hypertrophy to heart failure and reduces mortality in aortic-banded mice​
    Jacobshagen, C. ; Grueber, M.; Teucher, N. ; Schmidt, A.; Unsoeld, B. W.; Toischer, K.   & Van, P. N. et al.​ (2007)
    European Heart Journal28 
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Overexpression of FK-506-binding protein 12.0 modulates excitation-contraction coupling in adult rabbit ventricular cardiomyocytes​
    Seidler, T. ; Loughrey, C. M.; Zibrova, D.; Kettlewell, S.; Teucher, N. ; Koegler, H. & Hasenfuß, G.  et al.​ (2007) 
    Circulation Research101(10) pp. 1020​-1029​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.107.154609 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​alpha(1)-adrenergic stress induces downregulation of Na+/Ca2+ exchanger in myocardial preparations from rabbits at physiological preload​
    Schillinger, W. ; Christians, C.; Sossalla, S. ; Teucher, N. ; Van, P. N.; Koegler, H. & Zeitz, O. et al.​ (2007) 
    European Journal of Heart Failure9(4) pp. 329​-335​.​ DOI: https://doi.org/10.1016/j.ejheart.2006.10.014 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits - Evaluation of mechanisms​
    Schillinger, W. ; Teucher, N. ; Sossalla, S. ; Kettlewell, S.; Werner, C. ; Raddatz, D.   & Elgner, A. et al.​ (2007) 
    Circulation116(1) pp. 57​-66​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.106.666008 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​Surgical management of vascular graft infection in severely ill patients by partial resection of the infected prosthesis​
    Mirzaie, M.; Schmitto, J. D.; Tirilomis, T.; Fatehpur, S.; Liakopoulos, O. J.; Teucher, N.   & Doerge, H. et al.​ (2007) 
    European Journal of Vascular and Endovascular Surgery33(5) pp. 610​-613​.​ DOI: https://doi.org/10.1016/j.ejvs.2006.11.042 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Conference Abstract
    ​ ​Pharmacological inhibition of Akt signaling reduces LV-dilation and improves contractile function after TAC-induced LV pressure overload in mice​
    Jacobshagen, C. ; Grueber, M.; Kortlepel, S.; Teucher, N. ; Schmidt, A.; Unsoeld, B. W. & Koegler, H. et al.​ (2006)
    European Heart Journal27 , Barcelona, SPAIN.
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​Pantoprazole depresses contractile function of human and rabbit myocardium​
    Teucher, N. ; Sossalla, S. T.; Kettlewell, S.; Schondube, F. A.; Smith, G. L.; Schworer, H. & Hasenfuß, G.  et al.​ (2006)
    European Heart Journal27 , Barcelona, SPAIN.
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression​
    Koegler, H.; Schott, P. ; Toischer, K. ; Milting, H.; Van, P. N.; Kohlhaas, M. & Grebe, C. et al.​ (2006) 
    Circulation113(23) pp. 2724​-2732​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.608828 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts​
    Schillinger, W. ; Teucher, N. ; Christians, C.; Kohlhaas, M.; Sossalla, S. ; Van Nguyen, P. & Schmidt, A. G. et al.​ (2006) 
    European Journal of Heart Failure8(7) pp. 673​-680​.​ DOI: https://doi.org/10.1016/j.ejheart.2006.01.013 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Conference Abstract
    ​ ​FKBP12.6 overexpression in rabbit cardiomyocytes isolated from failing heart restores contractile function​
    Zibrova, D.; Seidler, T.; Teucher, N. ; Schillinger, W.; Christians, C.; Sosalla, S. T. & Kogler, H. et al.​ (2005)
    European Heart Journal26 ​27th Congress of the European-Society-of-Cardiology​, Stockholm, SWEDEN.
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2004 Conference Abstract
    ​ ​Novel role for brain natriuretic peptide to antagonize myocardial sarcoplasmic reticulum calcium-atpase expression​
    Kogler, H.; Schott, P.; Toischer, K. ; Oeynhausen, B.; van Phuc, N.; Kassner, A. & Teucher, N.  et al.​ (2004)
    Circulation110(17) ​77th Scientific Meeting of the American-Heart-Association​, New Orleans, LA.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2004 Conference Abstract
    ​ ​Contractility and intracellular sodium in pacing-induced heart failure​
    Schillinger, W.; Teucher, N. ; Zeitz, O.; Christians, C.; Kohlhaas, M.; van Nguyen, P. & Maier, L. S. et al.​ (2004)
    European Heart Journal25 ​ESC Congress 2004​, Munich, GERMANY.
    London​: W B Saunders Co Ltd.
    Details  WoS 
  • 2004 Conference Abstract
    ​ ​FKBP12.6 overexpression in rabbit cardiomyocytes isolated from failing heart restores contractile function​
    Zibrova, D.; Seidler, T.; Teucher, N. ; Schillinger, W.; Christians, C.; Kogler, H. & Hasenfuß, G. ​ (2004)
    Circulation110(17) ​77th Scientific Meeting of the American-Heart-Association​, New Orleans, LA.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2004 Conference Abstract
    ​ ​Pantoprazole induces a dose-dependent and reversible depression of contractile function in human myocardium​
    Teucher, N. ; Sossalla, S. T.; Sag, C. M.; Kockskaemper, J.; Unsoeld, B. W.; Schondube, F. A. & Schworer, H. et al.​ (2004)
    Circulation110(17) ​77th Scientific Meeting of the American-Heart-Association​, New Orleans, LA.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2004 Journal Article | Research Paper
    ​ ​Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening​
    Teucher, N. ; Prestle, J. ; Seidler, T. ; Currie, S.; Elliott, E. B.; Reynolds, D. F. & Schott, P.  et al.​ (2004) 
    Circulation110(23) pp. 3553​-3559​.​ DOI: https://doi.org/10.1161/01.CIR.0000145161.48545.B3 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Conference Abstract
    ​ ​The activity of the sarcolemmal Na pump determines the functional consequence of adenoviral Na/Ca exchanger overexpression​
    Schillinger, W.; Ohler, A.; Emami, S.; Mueller, F.; Koegler, H.; Teucher, N.   & Seidler, T. et al.​ (2003)
    European Heart Journal24 ​Congress of the European-Society-of-Cardiology​, VIENNA, AUSTRIA.
    London​: W B Saunders Co Ltd. DOI: https://doi.org/10.1016/S0195-668X(03)93865-6 
    Details  DOI  WoS 
  • 2003 Conference Abstract
    ​ ​Sorcin over-expression reduces contractility by affecting intracellular and trans-sarcolemmal Ca2+ cycling in cardiomyocytes​
    Seidler, T.; Miller, S.; Loughrey, C.; Kania, A.; Burow, A.; Teucher, N.   & Hasenfuß, G.  et al.​ (2003)
    European Heart Journal24 ​Congress of the European-Society-of-Cardiology​, VIENNA, AUSTRIA.
    London​: W B Saunders Co Ltd. DOI: https://doi.org/10.1016/S0195-668X(03)96074-X 
    Details  DOI  WoS 
  • 2003 Conference Abstract
    ​ ​Impaired contractile performance due to excessive SERCA expression and increased sarcoplasmic reticulum ca(2+)-uptake​
    Teucher, N. ; Prestle, J.; Seidler, T.; Elliott, E.; Reynolds, D.; Schott, P. & Wagner, S. et al.​ (2003)
    Circulation108(17) ​76th Annual Scientific Session of the American-Heart-Association​, ORLANDO, FLORIDA.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2003 Journal Article | Research Paper
    ​ ​Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes​
    Seidler, T. ; Miller, S. L. W.; Loughrey, C. M.; Kania, A.; Burow, A.; Kettlewell, S. & Teucher, N.  et al.​ (2003) 
    Circulation Research93(2) pp. 132​-139​.​ DOI: https://doi.org/10.1161/01.RES.0000081596.90205.E2 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article | Research Paper
    ​ ​Na+-Ca2+ exchanger overexpression predisposes to reactive oxygen species-induced injury​
    Wagner, S. ; Seidler, T. ; Picht, E.; Maier, L. S. ; Kazanski, V.; Teucher, N.   & Schillinger, W.  et al.​ (2003) 
    Cardiovascular Research60(2) pp. 404​-412​.​ DOI: https://doi.org/10.1016/j.cardiores.2003.08.006 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article
    ​ ​Differential regulation of Ca2+-dependent ATPase-activity in left ventricular myocardium during mechanical circulatory support​
    Milting, H.; Kassner, A.; Bothig, D.; Thieleczek, R.; Kogler, H.; Teucher, N.   & Meyer, H. E. et al.​ (2003) 
    The Journal of Heart and Lung Transplantation22(11) pp. 1209​-1216​.​ DOI: https://doi.org/10.1016/S1053-2498(02)01218-4 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article | Research Paper
    ​ ​The functional effect of adenoviral Na+/Ca2+ exchanger overexpression in rabbit myocytes depends on the activity of the Na+/K+-ATPase​
    Schillinger, W. ; Ohler, A.; Embry, S. L.; Muller, F.; Christians, C.; Janssen, P. M. L. & Kogler, H. et al.​ (2003) 
    Cardiovascular Research57(4) pp. 996​-1003​.​ DOI: https://doi.org/10.1016/S0008-6363(02)00829-5 
    Details  DOI  PMID  PMC  WoS 
  • 2002 Conference Abstract
    ​ ​FKBP12 overexpression in isolated rabbit cardiomyocytes enhances intracellular Ca2+ transients, SR Ca2+ content and contractility​
    Seidler, T.; Zibrova, D.; Reynolds, D.; Loughrey, C. M.; Kania, A.; Teucher, N.   & Wagner, S. et al.​ (2002)
    Circulation106(19) , CHICAGO, ILLINOIS.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2002 Conference Abstract
    ​ ​Mutation of the calcineurin binding site in FKBP12.6 leads to loss of the FKBP12.6 mediated increase in contractile performance​
    Seidler, T.; Kania, A.; Prestle, J.; Teucher, N. ; Kogler, H. & Hasenfuß, G. ​ (2002)
    European Heart Journal23 ​Congress of the European-Society-of-Cardiology​, BERLIN, GERMANY.
    London​: W B Saunders Co Ltd.
    Details  WoS 
  • 2002 Conference Abstract
    ​ ​Mutation of the calcineurin binding site in the 12.6 kDa FK-506 binding protein (FKBP12.6) leads to loss of the FKBP12.6 mediated increase in myocardial contractile performance​
    Seidler, T.; Kania, A.; Prestle, J.; Teucher, N. ; Wagner, S.; Kogler, H. & Hasenfuß, G. ​ (2002)
    Circulation106(19) , CHICAGO, ILLINOIS.
    Philadelphia​: Lippincott Williams & Wilkins.
    Details  WoS 
  • 2002 Conference Abstract
    ​ ​Dose-dependent effect of SERCA1-expression in rabbit isolated ventricular cardiomyocytes​
    Teucher, N. ; Prestle, J.; Seidler, T.; Smith, G. L.; Inesi, G.; Kogler, H. & Hasenfuß, G. ​ (2002)
    European Heart Journal23 , BERLIN, GERMANY.
    London​: W B Saunders Co Ltd.
    Details  WoS 
  • 2000 Journal Article
    ​ ​Impaired Contractile Performance of Cultured Rabbit Ventricular Myocytes After Adenoviral Gene Transfer of Na+-Ca2+ Exchanger​
    Schillinger, W. ; Janssen, P. M. L.; Emami, S.; Henderson, S. A.; Ross, R. S.; Teucher, N.   & Zeitz, O. et al.​ (2000) 
    Circulation Research87(7) pp. 581​-587​.​ DOI: https://doi.org/10.1161/01.res.87.7.581 
    Details  DOI  PMID  PMC  WoS 

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