Ole Jensen

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unigoe
 

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  • 2022 | Journal Article
    ​ ​Substrates and Inhibitors of the Organic Cation Transporter 3 and Comparison with OCT1 and OCT2​
    Gebauer, L.; Jensen, O. ; Brockmöller, J.   & Dücker, C.​ (2022) 
    Journal of Medicinal Chemistry, 65(18) pp. 12403​-12416​.​ DOI: https://doi.org/10.1021/acs.jmedchem.2c01075 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities​
    Doetsch, D. A.; Ansari, S.; Jensen, O. ; Gebauer, L.; Dücker, C.; Brockmöller, J.   & Sachkova, A.​ (2022) 
    International Journal of Molecular Sciences, 23(15) pp. 8430​.​ DOI: https://doi.org/10.3390/ijms23158430 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​The mystery of the human proton-organic cation antiporter: One transport protein or many?​
    Sachkova, A.; Jensen, O. ; Dücker, C.; Ansari, S. & Brockmöller, J. ​ (2022) 
    Pharmacology & Therapeutics, 239 art. 108283​.​ DOI: https://doi.org/10.1016/j.pharmthera.2022.108283 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation​
    Jensen, O. ; Brockmöller, J.   & Dücker, C.​ (2021) 
    Journal of Medicinal Chemistry, 64(5) pp. 2762​-2776​.​ DOI: https://doi.org/10.1021/acs.jmedchem.0c02047 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Cellular Uptake of Psychostimulants – Are High- and Low-Affinity Organic Cation Transporters Drug Traffickers?​
    Jensen, O. ; Rafehi, M. ; Gebauer, L. & Brockmöller, J. ​ (2021) 
    Frontiers in Pharmacology, 11.​ DOI: https://doi.org/10.3389/fphar.2020.609811 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​A double-Flp-in method for stable overexpression of two genes​
    Jensen, O. ; Ansari, S.; Gebauer, L.; Müller, S. F.; Lowjaga, K. A. A. T.; Geyer, J. & Tzvetkov, M. V.  et al.​ (2020) 
    Scientific Reports, 10(1).​ DOI: https://doi.org/10.1038/s41598-020-71051-5 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Stereoselective cell uptake of adrenergic agonists and antagonists by organic cation transporters​
    Jensen, O. ; Rafehi, M. ; Tzvetkov, M. V.   & Brockmöller, J. ​ (2020) 
    Biochemical Pharmacology, 171 pp. 113731​.​ DOI: https://doi.org/10.1016/j.bcp.2019.113731 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil​
    Matthaei, J. ; Seitz, T. ; Jensen, O. ; Tann, A.; Prukop, T. ; Tadjerpisheh, S. & Brockmöller, J.  et al.​ (2019) 
    Clinical Pharmacology and Therapeutics, 105(1) pp. 190​-200​.​ DOI: https://doi.org/10.1002/cpt.1128 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Variability and heritability of thiamine pharmacokinetics with focus on OCT1 effects on membrane transport and pharmacokinetics in humans​
    Jensen, O. ; Matthaei, J. ; Blome, F.; Schwab, M.; Tzvetkov, M. V.   & Brockmöller, J. ​ (2019) 
    Clinical Pharmacology and Therapeutics, 107(3) pp. 628​-638​.​ DOI: https://doi.org/10.1002/cpt.1666 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis​
    Mewes, C.; Büttner, B. ; Hinz, J. M. ; Alpert, A.; Popov, A.-F.; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2019) 
    Journal of Clinical Medicine, 8(1) art. 70​.​ DOI: https://doi.org/10.3390/jcm8010070 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A​
    Rafehi, M. ; Faltraco, F.; Matthaei, J. ; Prukop, T. ; Jensen, O. ; Grytzmann, A. & Berger, R. G. et al.​ (2019) 
    Frontiers in Pharmacology, 10 pp. 1297​.​ DOI: https://doi.org/10.3389/fphar.2019.01297 
    ​Details  DOI  PMID  PMC 

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