Prof. Dr. Uwe Michel

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unigoe
 

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  • 2015 | Journal Article | Research Paper
    ​ ​AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury​
    Challagundla, M.; Koch, J. C. ; Ribas, V. T. ; Michel, U. ; Kügler, S. ; Ostendorf, T. & Bradke, F. et al.​ (2015) 
    Journal of Neurochemistry, 134(2) pp. 261​-275​.​ DOI: https://doi.org/10.1111/jnc.13102 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons​
    Koch, J. C. ; Bitow, F.; Haack, J.; D'Hedouville, Z.; Zhang, J.-N.; Tönges, L.   & Michel, U.  et al.​ (2015) 
    Cell Death and Disease, 6 art. e1811​.​ DOI: https://doi.org/10.1038/cddis.2015.169 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo​
    Saal, K.-A. ; Koch, J. C. ; Tatenhorst, L. ; Szegő, É. M. ; Ribas, V. T. ; Michel, U.   & Bähr, M.  et al.​ (2015) 
    Neurobiology of Disease, 73 pp. 150​-162​.​ DOI: https://doi.org/10.1016/j.nbd.2014.09.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells​
    Koch, J. C. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Frontiers in Cellular Neuroscience, 8 art. 273​.​ DOI: https://doi.org/10.3389/fncel.2014.00273 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS​
    Koch, J. C. ; Tönges, L. ; Barski, E. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Cell Death and Disease, 5 art. e1225​.​ DOI: https://doi.org/10.1038/cddis.2014.191 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation​
    Doeppner, T. R. ; Doehring, M.; Bretschneider, E. ; Zechariah, A.; Kaltwasser, B.; Müller, B. & Koch, J. C.  et al.​ (2013) 
    Acta Neuropathologica, 126(2) pp. 251​-265​.​ DOI: https://doi.org/10.1007/s00401-013-1142-5 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro​
    Koch, J. C. ; Solis, G. P.; Bodrikov, V.; Michel, U. ; Haralampieva, D.; Shypitsyna, A. & Tönges, L.  et al.​ (2013) 
    Neurobiology of Disease, 51 pp. 168​-176​.​ DOI: https://doi.org/10.1016/j.nbd.2012.11.007 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper
    ​ ​Imaging of rat optic nerve axons in vivo​
    Koch, J. C. ; Knöferle, J. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2011) 
    Nature Protocols, 6(12) pp. 1887​-1896​.​ DOI: https://doi.org/10.1038/nprot.2011.403 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper
    ​ ​Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression​
    Koch, J. C. ; Barski, E. ; Lingor, P. ; Bähr, M.   & Michel, U. ​ (2011) 
    FEBS Journal, 278(18) pp. 3472​-3483​.​ DOI: https://doi.org/10.1111/j.1742-4658.2011.08269.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | Research Paper
    ​ ​TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP​
    Knöferle, J. ; Ramljak, S. ; Koch, J. C. ; Tönges, L. ; Asif, A. R. ; Michel, U.   & Wouters, F. S.  et al.​ (2010) 
    Neurobiology of Disease, 38(3) pp. 395​-404​.​ DOI: https://doi.org/10.1016/j.nbd.2010.02.011 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | Research Paper
    ​ ​Mechanisms of acute axonal degeneration in the optic nerve in vivo​
    Knöferle, J. ; Koch, J. C. ; Ostendorf, T.; Michel, U. ; Planchamp, V. ; Vutova, P. & Tönges, L.  et al.​ (2010) 
    Proceedings of the National Academy of Sciences, 107(13) pp. 6064​-6069​.​ DOI: https://doi.org/10.1073/pnas.0909794107 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | Research Paper
    ​ ​Evaluation of epitope tags for protein detection after in vivo CNS gene transfer​
    Shevtsova, Z.; Malik, J. M. I.; Michel, U. ; Scholl, U.; Bähr, M.   & Kugler, S. ​ (2006) 
    European Journal of Neuroscience, 23(8) pp. 1961​-1969​.​ DOI: https://doi.org/10.1111/j.1460-9568.2006.04725.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | Research Paper
    ​ ​Comparison of test systems for RNAinterference​
    Malik, I. ; Garrido, M.; Bähr, M. ; Kügler, S.   & Michel, U. ​ (2006) 
    Biochemical and Biophysical Research Communications, 341(1) pp. 245​-253​.​ DOI: https://doi.org/10.1016/j.bbrc.2005.12.173 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Limited protection of TAT-Bcl-X-L against pneumolysin-induced neuronal cell death​
    Ebert, S.; Dietz, G. P. H. ; Mitchell, T. J.; Michel, U. ; Bähr, M.   & Nau, R. ​ (2005) 
    Neuroscience Letters, 384(3) pp. 349​-353​.​ DOI: https://doi.org/10.1016/j.neulet.2005.05.027 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons​
    Michel, U. ; Malik, I. ; Ebert, S.; Bähr, M.   & Kugler, S. ​ (2005) 
    Biochemical and Biophysical Research Communications, 326(2) pp. 307​-312​.​ DOI: https://doi.org/10.1016/j.bbrc.2004.11.029 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Conference Paper | Research Paper
    ​ ​Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo​
    Shevtsova, Z.; Malik, J. M. I.; Michel, U. ; Bähr, M.   & Kugler, S. ​ (2005)
    ​Experimental Physiology (1) pp. 53​-59. (Vol. 90). ​Meeting on Viral Gene Transfer in Neuroscience​, Univ Bristol, Bristol, ENGLAND.
    Oxford​: Blackwell Publishing Ltd. DOI: https://doi.org/10.1113/expphysiol.2004.028159 
    ​Details  DOI  PMID  PMC  WoS 
  • 2004 | Journal Article | Research Paper
    ​ ​Transfection of "naked" siRNA results in endosomal uptake and metabolic impairment in cultured neurons​
    Lingor, P. ; Michel, U. ; Scholl, U.; Bähr, M.   & Kugler, S. ​ (2004) 
    Biochemical and Biophysical Research Communications, 315(4) pp. 1126​-1133​.​ DOI: https://doi.org/10.1016/j.bbrc.2004.01.170 
    ​Details  DOI  PMID  PMC  WoS 
  • 2002 | Conference Paper | Research Paper
    ​ ​Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase​
    Stringaris, A.; Geisenhainer, J.; Bergmann, F. ; Balshusemann, C.; Lee, U.; Zysk, G. & Mitchell, T. J. et al.​ (2002)
    ​Neurobiology of Disease (3) pp. 355​-368. (Vol. 11). ​54th Annual Meeting of the American-Academy-of-Neurology​, DENVER, COLORADO.
    San diego​: Academic Press Inc Elsevier Science. DOI: https://doi.org/10.1006/nbdi.2002.0561 
    ​Details  DOI  PMID  PMC  WoS 

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