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  • 2024 Journal Article
    ​ ​H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6​
    Sokpor, G.; Kerimoglu, C.; Ulmke, P. A.; Pham, L.; Nguyen, H. D.; Brand-Saberi, B. & Staiger, J. F. et al.​ (2024) 
    Biology13(2) pp. 68​.​ DOI: https://doi.org/10.3390/biology13020068 
    Details  DOI 
  • 2024 Journal Article
    ​ ​A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise​
    Methi, A.; Islam, M. R.; Kaurani, L.; Sakib, M S.; Krüger, D. M.; Pena, T. & Burkhardt, S. et al.​ (2024) 
    Molecular Neurobiology,.​ DOI: https://doi.org/10.1007/s12035-023-03869-9 
    Details  DOI 
  • 2023 Journal Article | 
    ​ ​Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency​
    Schlotawa, L.; Tyka, K.; Kettwig, M.; Ahrens‐Nicklas, R. C.; Baud, M.; Berulava, T. & Brunetti‐Pierri, N. et al.​ (2023) 
    EMBO Molecular Medicine15(3) art. e14837​.​ DOI: https://doi.org/10.15252/emmm.202114837 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article
    ​ ​Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF​
    Antoniou, A.; Auderset, L.; Kaurani, L.; Sebastian, E.; Zeng, Y.; Allahham, M. & Cases-Cunillera, S. et al.​ (2023) 
    Cell Reports42(2) art. 112063​.​ DOI: https://doi.org/10.1016/j.celrep.2023.112063 
    Details  DOI  PMID  PMC 
  • 2023 Preprint
    ​ ​A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia​
    Kaurani, L.; Islam, M. R.; Heilbronner, U.; Krüger, D. M.; Zhou, J.; Methi, A.& Strauss, J. et al.​ (2023). DOI: https://doi.org/10.1101/2023.03.21.533602 
    Details  DOI 
  • 2023 Conference Paper
    ​ ​Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency​
    Schlotawa, L.; Matysiak, K.; Kettwig, M.; Ahrens-Nicklas, R. C.; Baud, M.; Berulava, T. & Brunetti-Pierri, N. et al.​ (2023)
    Neuropediatrics54(S01) pp. S1​-S32. ​German Neuropediatric Society Congress 2023​, Dortmund. DOI: https://doi.org/10.1055/s-0043-1777171 
    Details  DOI 
  • 2023 Preprint
    ​ ​Bioengineering of a human innervated cardiac muscle model​
    Schneider, L. V.; Guobin, B.; Methi, A.; Jensen, O.; Schmoll, K. A.; Setya, M. G.& Sakib, S. et al.​ (2023). DOI: https://doi.org/10.1101/2023.08.18.552653 
    Details  DOI 
  • 2023 Journal Article
    ​ ​Regulatory roles of the N6-methyladenosine demethylase FTO in cardiac remodeling​
    Annamalai, K.; Buchholz, E.; Castro, R.; Panyam, N.; Fischer, A. & Toischer, K.​ (2023) 
    European Heart Journal44(Supplement 2).​ DOI: https://doi.org/10.1093/eurheartj/ehad655.3143 
    Details  DOI 
  • 2023 Journal Article | 
    ​ ​Metabolic switch from fatty acid oxidation to glycolysis in knock‐in mouse model of Barth syndrome​
    Chowdhury, A.; Boshnakovska, A.; Aich, A.; Methi, A.; Vergel Leon, A. M.; Silbern, I. & Lüchtenborg, C. et al.​ (2023) 
    EMBO Molecular Medicine, art. e17399​.​ DOI: https://doi.org/10.15252/emmm.202317399 
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  • 2023 Journal Article
    ​ ​Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome​
    Akol, I.; Izzo, A.; Gather, F.; Strack, S.; Heidrich, S.; Ó hAilín, D. & Villarreal, A. et al.​ (2023) 
    Proceedings of the National Academy of Sciences120(2) art. e2122467120​.​ DOI: https://doi.org/10.1073/pnas.2122467120 
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  • 2023 Journal Article
    ​ ​Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls​
    Senner, F.; Schneider-Axmann, T.; Kaurani, L.; Zimmermann, J.; Wiltfang, J.; von Hagen, M. & Vogl, T. et al.​ (2023) 
    Schizophrenia Research: Cognition32 art. 100280​.​ DOI: https://doi.org/10.1016/j.scog.2023.100280 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article
    ​ ​NFATc1 is a central mediator of EGFR-induced ARID1A chromatin dissociation during acinar cell reprogramming​
    Zhang, Z.; Wang, X.; Hamdan, F. H.; Likhobabina, A.; Patil, S.; Aperdannier, L. & Sen, M. et al.​ (2023) 
    Cellular and Molecular Gastroenterology and Hepatology,.​ DOI: https://doi.org/10.1016/j.jcmgh.2023.01.015 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article | 
    ​ ​Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression​
    Kaurani, L.; Besse, M.; Methfessel, I.; Methi, A.; Zhou, J.; Pradhan, R. & Burkhardt, S. et al.​ (2023) 
    Translational Psychiatry13(1).​ DOI: https://doi.org/10.1038/s41398-023-02582-4 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article | 
    ​ ​Metabolomic Profiling in Patients with Different Hemodynamic Subtypes of Severe Aortic Valve Stenosis​
    Bengel, P.; Elkenani, M.; Beuthner, B. E.; Pietzner, M.; Mohamed, B. A.; Pollok-Kopp, B. & Krätzner, R. et al.​ (2023) 
    Biomolecules13(1) pp. 95​.​ DOI: https://doi.org/10.3390/biom13010095 
    Details  DOI  PMID  PMC 
  • 2023 Journal Article
    ​ ​Conserved reduction of m 6 A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts​
    Castro-Hernández, R.; Berulava, T.; Metelova, M.; Epple, R.; Peña Centeno, T.; Richter, J. & Kaurani, L. et al.​ (2023) 
    Proceedings of the National Academy of Sciences120(9) art. e2204933120​.​ DOI: https://doi.org/10.1073/pnas.2204933120 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | 
    ​ ​Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy​
    Shahriyari, M.; Islam, M. R.; Sakib, S. M.; Rinn, M.; Rika, A.; Krüger, D. & Kaurani, L. et al.​ (2022) 
    Journal of Cachexia, Sarcopenia and Muscle13(6) art. jcsm.13094​.​ DOI: https://doi.org/10.1002/jcsm.13094 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3​
    Baidoe-Ansah, D.; Sakib, S.; Jia, S.; Mirzapourdelavar, H.; Strackeljan, L.; Fischer, A.   & Aleshin, S. et al.​ (2022) 
    Cells11(13).​ DOI: https://doi.org/10.3390/cells11132033 
    Details  DOI  PMID  PMC 
  • 2022 Preprint
    ​ ​Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts​
    Castro-Hernández, R.; Berulava, T.; Metelova, M.; Epple, R.; Centeno, T. P.; Sakib, M S.& Burkhart, S. et al.​ (2022). DOI: https://doi.org/10.1101/2022.06.08.495100 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance​
    Ding, Y.; Korchak, S.; Mamone, S.; Jagtap, A. P.; Stevanato, G.; Sternkopf, S. & Moll, D. et al.​ (2022) 
    Chemistry Methods2(7).​ DOI: https://doi.org/10.1002/cmtd.202200023 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501​
    Goldberg, M.; Islam, M. R.; Kerimoglu, C.; Lancelin, C.; Gisa, V.; Burkhardt, S. & Krüger, D. M. et al.​ (2021) 
    Translational Psychiatry11(1) art. 514​.​ DOI: https://doi.org/10.1038/s41398-021-01627-w 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Erratum | 
    ​ ​Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome​
    Epple, R.; Krüger, D.; Berulava, T.; Brehm, G. ; Ninov, M.; Islam, R. & Köster, S.  et al.​ (2021) 
    Molecular Neurobiology,.​ DOI: https://doi.org/10.1007/s12035-021-02349-2 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​The Coding and Small Non-coding Hippocampal Synaptic RNAome​
    Epple, R.; Krüger, D.; Berulava, T.; Brehm, G. ; Ninov, M.; Islam, R. & Köster, S.  et al.​ (2021) 
    Molecular Neurobiology,.​ DOI: https://doi.org/10.1007/s12035-021-02296-y 
    Details  DOI  PMID  PMC 
  • 2021 Preprint
    ​ ​Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity​
    Shahriyari, M.; Islam, M. R.; Sakib, M. S.; Rika, A.; Krüger, D.; Kaurani, L.& Anandakumar, H. et al.​ (2021). DOI: https://doi.org/10.1101/2021.07.12.452030 
    Details  DOI 
  • 2021 Preprint
    ​ ​Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus​
    Akol, I.; Heidrich, S.; ÓhAilín, D.; Hacker, C.; Villarreal, A.; Rauleac, T.& Bella, C. et al.​ (2021). DOI: https://doi.org/10.1101/2021.10.25.465562 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes​
    Michurina, A.; Sakib, M S.; Kerimoglu, C. ; Krüger, D. M.; Kaurani, L. ; Islam, M. R. & Joshi, P. D. et al.​ (2021) 
    The EMBO Journal,.​ DOI: https://doi.org/10.15252/embj.2020106459 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue​
    Sakib, M. S.; Sokpor, G. ; Nguyen, H. P.; Fischer, A.   & Tuoc, T. ​ (2021) 
    STAR Protocols2(1) pp. 100318​.​ DOI: https://doi.org/10.1016/j.xpro.2021.100318 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo​
    Thom, T.; Schmitz, M.; Fischer, A.; Correia, A.; Correia, S.; Llorens, F. & Pique, A. et al.​ (2021) 
    Movement Disorders37(1) art. mds.28774​.​ DOI: https://doi.org/10.1002/mds.28774 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain​
    Abbas, E.; Hassan, M. A.; Sokpor, G.; Kiszka, K.; Pham, L.; Kerimoglu, C. & Fischer, A.  et al.​ (2021) 
    Frontiers in Cell and Developmental Biology9.​ DOI: https://doi.org/10.3389/fcell.2021.619538 
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  • 2021 Journal Article | Research Paper | 
    ​ ​A microRNA signature that correlates with cognition and is a target against cognitive decline​
    Islam, M. R.; Kaurani, L.; Berulava, T.; Heilbronner, U.; Budde, M.; Centeno, T. P. & Elerdashvili, V. et al.​ (2021) 
    EMBO Molecular Medicine13(11).​ DOI: https://doi.org/10.15252/emmm.202013659 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling​
    Ulmke, P. A.; Xie, Y.; Sokpor, G. ; Pham, L.; Shomroni, O. ; Berulava, T. & Rosenbusch, J.  et al.​ (2021) 
    Development148(3) pp. dev188276​.​ DOI: https://doi.org/10.1242/dev.188276 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex​
    Ulmke, P. A.; Sakib, M. S.; Ditte, P.; Sokpor, G. ; Kerimoglu, C. ; Pham, L. & Xie, Y. et al.​ (2021) 
    Stem Cell Reports16(4) pp. 968​-984​.​ DOI: https://doi.org/10.1016/j.stemcr.2021.03.008 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Epigenetic gene expression links heart failure to memory impairment​
    Islam, M. R.; Lbik, D.; Sakib, M S.; Maximilian Hofmann, R.; Berulava, T.; Jiménez Mausbach, M. & Cha, J. et al.​ (2021) 
    EMBO Molecular Medicine13(3).​ DOI: https://doi.org/10.15252/emmm.201911900 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy​
    Kettwig, M.; Ternka, K.; Wendland, K.; Krüger, D. M.; Zampar, S.; Schob, C. & Franz, J. et al.​ (2021) 
    Nature Communications12(1) art. 6530​.​ DOI: https://doi.org/10.1038/s41467-021-26880-x 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner​
    Sokpor, G. ; Kerimoglu, C. ; Nguyen, H. ; Pham, L.; Rosenbusch, J. ; Wagener, R. & Nguyen, H. P. et al.​ (2021) 
    Frontiers in Molecular Neuroscience14.​ DOI: https://doi.org/10.3389/fnmol.2021.687581 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion​
    Kerimoglu, C. ; Pham, L.; Tonchev, A. B.; Sakib, M. S.; Xie, Y.; Sokpor, G.   & Ulmke, P. A. et al.​ (2021) 
    Science Advances7(38).​ DOI: https://doi.org/10.1126/sciadv.abc6792 
    Details  DOI  PMID  PMC 
  • 2020 Preprint
    ​ ​The Coding And Small-Non-Coding Hippocampal Synaptic RNAome​
    Epple, R.; Krüger, D.; Berulava, T.; Brehm, G.; Islam, R.; Köster, S.  & Fischer, A. ​ (2020). DOI: https://doi.org/10.1101/2020.11.27.401901 
    Details  DOI 
  • 2020 Preprint
    ​ ​SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​
    Michurina, A.; Sakib, S.; Kerimoglu, C.; Krüger, D. M.; Kaurani, L.; Islam, R.& Centeno, T. P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.07.240853 
    Details  DOI 
  • 2020 Preprint
    ​ ​A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19​
    Islam, M. R.& Fischer, A. ​ (2020). DOI: https://doi.org/10.20944/preprints202004.0399.v1 
    Details  DOI 
  • 2020 Preprint
    ​ ​Epigenetic gene-expression links heart failure to memory impairment​
    Islam, R.; Lbik, D.; Sakib, S.; Hofmann, R. M.; Berulava, T.; Mausbach, M. J.& Cha, J. et al.​ (2020). DOI: https://doi.org/10.1101/2020.01.22.915637 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids​
    Zafeiriou, M.-P. ; Bao, G. ; Hudson, J. ; Halder, R. ; Blenkle, A.; Schreiber, M.-K. & Fischer, A.  et al.​ (2020) 
    Nature Communications11(1).​ DOI: https://doi.org/10.1038/s41467-020-17521-w 
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  • 2020 Journal Article | Research Paper
    ​ ​Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control​
    Hu, Y.; Korovaichuk, A.; Astiz, M.; Schroeder, H.; Islam, R.; Barrenetxea, J. & Fischer, A.  et al.​ (2020) 
    Genetics216(3) pp. 735​-752​.​ DOI: https://doi.org/10.1534/genetics.120.303533 
    Details  DOI  PMID  PMC 
  • 2019 Conference Paper
    ​ ​1180 Cardiomyocyte-specific deletion of Brd4 induces hypertrophic cardiomyopathy and suggests a novel function for the chromatin reader as co-repressor in the healthy heart​
    Lbik, D.; Buchholz, E.; Mohamed, B.; Fischer, A. ; Hasenfuss, G.   & Toischer, K. ​ (2019)
    European Heart Journal40(Suppl. 1) ​ESC Congress 2019 together with World Congress of Cardiology​, Paris. DOI: https://doi.org/10.1093/eurheartj/ehz748.0022 
    Details  DOI 
  • 2019 Conference Paper
    ​ ​P1621m6A RNA-methylation in the progression of heart failure​
    Buchholz, E.; Berulava, T.; Ellerdashvilli, V.; Pena, T.; Lbik, D.; Mohamed, B. & Sloan, K. et al.​ (2019)
    European Heart Journal40(Suppl. 1) ​ESC Congress 2019 together with World Congress of Cardiology​, Paris. DOI: https://doi.org/10.1093/eurheartj/ehz748.0380 
    Details  DOI 
  • 2019 Journal Article | Research Paper | 
    ​ ​A combined miRNA–piRNA signature to detect Alzheimer’s disease​
    Jain, G.; Stuendl, A.; Rao, P.; Berulava, T.; Pena Centeno, T.; Kaurani, L.   & Burkhardt, S.  et al.​ (2019) 
    Translational Psychiatry9(1).​ DOI: https://doi.org/10.1038/s41398-019-0579-2 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​Changes in m6A RNA methylation contribute to heart failure progression by modulating translation​
    Berulava, T.; Buchholz, E.; Elerdashvili, V.; Pena, T.; Islam, M. R.; Lbik, D. & Mohamed, B. A.  et al.​ (2019) 
    European Journal of Heart Failure22(1) pp. 54​-66​.​ DOI: https://doi.org/10.1002/ejhf.1672 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper
    ​ ​Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein​
    Pinho, R.; Paiva, I.; Jercic, K. G.; Fonseca-Ornelas, L.; Gerhardt, E.; Fahlbusch, C. & Garcia-Esparcia, P. et al.​ (2019) 
    Human Molecular Genetics28(1) pp. 31​-50​.​ DOI: https://doi.org/10.1093/hmg/ddy326 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper
    ​ ​A 2A R‐induced transcriptional deregulation in astrocytes: An in vitro study​
    Paiva, I. ; Carvalho, K.; Santos, P.; Cellai, L.; Pavlou, M. A. S. ; Jain, G. & Gnad, T. et al.​ (2019) 
    Glia67(12) pp. 2329​-2342​.​ DOI: https://doi.org/10.1002/glia.23688 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper
    ​ ​Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism​
    Gong, J.; Szego, É. M. ; Leonov, A. ; Benito, E. ; Becker, S. ; Fischer, A.   & Zweckstetter, M.  et al.​ (2019) 
    The Journal of Neuroscience39(19) pp. 3752​-3769​.​ DOI: https://doi.org/10.1523/JNEUROSCI.2070-18.2019 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia​
    Chowdhury, A. ; Aich, A. ; Jain, G.; Wozny, K.; Lüchtenborg, C.; Hartmann, M.   & Bernhard, O.  et al.​ (2018) 
    Cell Reports25(3) pp. 561​-570.e6​.​ DOI: https://doi.org/10.1016/j.celrep.2018.09.057 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain​
    Mandad, S.; Rahman, R.-U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B. & Keihani, S. et al.​ (2018) 
    Scientific Reports8(1) art. 16913​.​ DOI: https://doi.org/10.1038/s41598-018-35277-8 
    Details  DOI  PMID  PMC 

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