Prof. Dr. Heike Bickeböller

 
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  • 2022 Journal Article | Research Paper | 
    ​ ​Thormann, Kolja A., Viola Tozzi, Paula Starke, Heike Bickeböller, Marcus Baum, and Albert Rosenberger. "ImputAccur: fast and user-friendly calculation of genotype-imputation accuracy-measures​." ​BMC Bioinformatics ​23, no. 1 (2022): ​316​. ​https://doi.org/10.1186/s12859-022-04863-z.
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  • 2022 Journal Article | 
    ​ ​Yang, Wenjun, Hongliang Liu, Ruoxin Zhang, Jennifer A. Freedman, Younghun Han, Rayjean J. Hung, Yonathan Brhane et al. "Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk​." ​npj Precision Oncology ​6, no. 1 (2022): . ​https://doi.org/10.1038/s41698-022-00281-9.
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  • 2021 Journal Article
    ​ ​Hung, Rayjean J., Matthew T. Warkentin, Yonathan Brhane, Nilanjan Chatterjee, David C. Christiani, Maria Teresa Landi, Neil E. Caporaso et al. "Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model​." ​Cancer Research ​81, no. 6 (2021): ​1607​-1615​. ​https://doi.org/10.1158/0008-5472.CAN-20-1237.
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  • 2021 Journal Article | Research Paper
    ​ ​Rosenberger, Albert, Viola Tozzi, Marcus Baum, Kolja Thormann, Rayjean J. Hung, Christopher I. Amos, and Heike Bickeboeller. "I'am hiQ - A Novel Pair of Accuracy Indices for Imputed Genotypes​." ​Genetic Epidemiology ​45, no. 7 (2021): ​786​. ​
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  • 2021 Journal Article | Research Paper | 
    ​ ​Islam, Md Rezaul, Lalit Kaurani, Tea Berulava, Urs Heilbronner, Monika Budde, Tonatiuh Pena Centeno, Vakthang Elerdashvili et al. "A microRNA signature that correlates with cognition and is a target against cognitive decline​." ​EMBO Molecular Medicine ​13, no. 11 (2021): . ​https://doi.org/10.15252/emmm.202013659.
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  • 2020 Journal Article
    ​ ​Zhou, Wen, Geoffrey Liu, Rayjean J. Hung, Philip C. Haycock, Melinda C. Aldrich, Angeline S. Andrew, Susanne M. Arnold et al. "Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization​." ​International Journal of Cancer ​148, no. 5 (2020): ​1077​-1086​. ​https://doi.org/10.1002/ijc.33292.
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  • 2020 Journal Article
    ​ ​Dai, Juncheng, Mingtao Huang, Christopher I. Amos, Rayjean J. Hung, Adonina Tardon, Angeline Andrew, Chu Chen et al. "Genome‐wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk​." ​International Journal of Cancer ​146, no. 10 (2020): ​2855​-2864​. ​https://doi.org/10.1002/ijc.32698.
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  • 2020 Journal Article
    ​ ​Partanen, Jukka, Kati Hyvärinen, Heike Bickeböller, Katarzyna Bogunia-Kubik, Rachel E. Crossland, Milena Ivanova, Francesca Perutelli, and Ralf Dressel. "Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation​." ​Frontiers in Immunology ​11 (2020): . ​https://doi.org/10.3389/fimmu.2020.575492.
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  • 2020 Journal Article
    ​ ​Qin, Na, Yuancheng Li, Cheng Wang, Meng Zhu, Juncheng Dai, Tongtong Hong, Demetrius Albanes et al. "Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma​." ​Frontiers of Medicine (2020): . ​https://doi.org/10.1007/s11684-020-0779-4.
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  • 2020 Journal Article
    ​ ​Wang, Yuzhuo, Olga Y. Gorlova, Ivan P. Gorlov, Meng Zhu, Juncheng Dai, Demetrius Albanes, Stephen Lam et al. "Association Analysis of Driver Gene–Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls​." ​Cancer Epidemiology Biomarkers & Prevention ​29, no. 7 (2020): ​1423​-1429​. ​https://doi.org/10.1158/1055-9965.EPI-19-1085.
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  • 2020 Journal Article | 
    ​ ​Kachuri, Linda, Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem, Neil E. Caporaso et al. "Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility​." ​Nature Communications ​11, no. 1 (2020): . ​https://doi.org/10.1038/s41467-019-13855-2.
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  • 2019 Journal Article | 
    ​ ​Budde, Monika, Stefanie Friedrichs, Ney Alliey-Rodriguez, Seth Ament, Judith A. Badner, Wade H. Berrettini, Cinnamon S. Bloss et al. "Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder​." ​European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology ​29, no. 1 (2019): ​156​-170​. ​https://doi.org/10.1016/j.euroneuro.2018.10.005.
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  • 2019 Journal Article
    ​ ​Klein, Nadja, Andrew Entwistle, Albert Rosenberger, Thomas Kneib, and Heike Bickeböller. "Candidate-gene association analysis for a continuous phenotype with a spike at zero using parent-offspring trios​." ​Journal of Applied Statistics (2019): ​1​-15​. ​https://doi.org/10.1080/02664763.2019.1704226.
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  • 2019 Journal Article
    ​ ​Heilbronner, Urs, Bernadette Wendel, Monika Budde, Katrin Gade, Kristina Adorjan, Janos Kalman, Fanny Senner et al. "S46A GENOME-WIDE ASSOCIATION STUDY OF THE LONGITUDINAL COURSE OF EXECUTIVE FUNCTIONS​." ​European Neuropsychopharmacology ​29 (2019): ​S137​-S138​. ​https://doi.org/10.1016/j.euroneuro.2019.08.047.
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  • 2019 Journal Article
    ​ ​Heilbronner, Urs, Bernadette Wendel, Monika Budde, Katrin Gade, Kristina Adorjan, Janos Kalman, Fanny Senner et al. "SU53A CROSS-DIAGNOSTIC GWAS OF LONGITUDINAL EXECUTIVE FUNCTION PROFILE SCORES​." ​European Neuropsychopharmacology ​29 (2019): ​S1295​-S1296​. ​https://doi.org/10.1016/j.euroneuro.2018.08.417.
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  • 2019 Journal Article
    ​ ​Bossé, Yohan, Zhonglin Li, Jun Xia, Venkata Manem, Robert Carreras-Torres, Aurélie Gabriel, Nathalie Gaudreault et al. "Transcriptome-wide association study reveals candidate causal genes for lung cancer​." ​International Journal of Cancer (2019): . ​https://doi.org/10.1002/ijc.32771.
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  • 2019 Journal Article | 
    ​ ​Hung, Rayjean J., Margaret R. Spitz, Richard S. Houlston, Ann G. Schwartz, John K. Field, Jun Ying, Yafang Li et al. "Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region​." ​Journal of Thoracic Oncology ​14, no. 8 (2019): ​1360​-1369​. ​https://doi.org/10.1016/j.jtho.2019.04.008.
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  • 2019 Journal Article | 
    ​ ​Papiol, Sergi, Daniel Keeser, Alkomiet Hasan, Thomas Schneider-Axmann, Florian Raabe, Franziska Degenhardt, Moritz J. Rossner et al. "Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients​." ​Translational Psychiatry ​9, no. 1 (2019): ​284​. ​https://doi.org/10.1038/s41398-019-0618-z.
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  • 2019 Journal Article | 
    ​ ​Tozzi, Viola, Albert Rosenberger, Dieter Kube, and Heike Bickeböller. "Global, pathway and gene coverage of three Illumina arrays with respect to inflammatory and immune-related pathways​." ​European Journal of Human Genetics ​27, no. 11 (2019): ​1716​-1723​. ​https://doi.org/10.1038/s41431-019-0441-2.
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  • 2019 Journal Article
    ​ ​Zhu, Ying, Yongyue Wei, Ruyang Zhang, Xuesi Dong, Sipeng Shen, Yang Zhao, Jianling Bai et al. "Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis​." ​Cancer Epidemiology, Biomarkers & Prevention ​28, no. 5 (2019): ​935​-942​. ​https://doi.org/10.1158/1055-9965.EPI-18-0356.
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  • 2018 Journal Article
    ​ ​Kachuri, Linda, Olli Saarela, Stig Egil Bojesen, George Davey Smith, Geoffrey Liu, Maria Teresa Landi, Neil E Caporaso et al. "Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers​." ​International Journal of Epidemiology ​48, no. 3 (2018): ​751​-766​. ​https://doi.org/10.1093/ije/dyy140.
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  • 2018 Journal Article
    ​ ​Rosenberger, Albert, Rayjean J. Hung, David C. Christiani, Neil E. Caporaso, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand et al. "Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners​." ​International Archives of Occupational and Environmental Health ​91, no. 8 (2018): ​937​-950​. ​https://doi.org/10.1007/s00420-018-1334-3.
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  • 2018 Journal Article | 
    ​ ​Yasmeen, Summaira, Patricia Burger, Stefanie Friedrichs, Sergi Papiol, and Heike Bickeböller. "Relating drug response to epigenetic and genetic markers using a region-based kernel score test​." ​BMC Proceedings ​12, no. Suppl 9 (2018): ​47​. ​https://doi.org/10.1186/s12919-018-0154-5.
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  • 2018 Journal Article | 
    ​ ​Ferreiro-Iglesias, Aida, Corina Lesseur, James McKay, Rayjean J. Hung, Younghun Han, Xuchen Zong, David Christiani et al. "Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity​." ​Nature Communications ​9, no. 1 (2018): . ​https://doi.org/10.1038/s41467-018-05890-2.
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  • 2018 Journal Article | 
    ​ ​Cherlin, Svetlana, Maggie Haitian Wang, Heike Bickeböller, and Rita M Cantor. "Detecting responses to treatment with fenofibrate in pedigrees​." ​BMC Genetics ​19, no. Suppl 1 (2018): ​64​. ​https://doi.org/10.1186/s12863-018-0652-5.
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  • 2017 Journal Article
    ​ ​Loesgen, Sabine, Astrid Dempfle, Astrid Golla, and Heike Bickeböller. "Weighting Schemes in Pooled Linkage Analysis​." ​Genetic Epidemiology ​21, no. S1 (2017): ​S142​-S147​. ​https://doi.org/10.1002/gepi.2001.21.s1.s142.
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  • 2017 Conference Paper
    ​ ​Kachuri, Linda, Mattias Johansson, Paul Brennan, Phillip Haycock, Geoffrey Liu, Maria Teresa Landi, David C. Christiani et al. "Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium​." ​​2292​-2292. ​2017. https://doi.org/10.1158/1538-7445.AM2017-2292.
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  • 2017 Journal Article
    ​ ​Feng, Yun, Yanru Wang, Hongliang Liu, Zhensheng Liu, Coleman Mills, Kouros Owzar, Jichun Xie et al. "Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer​." ​Molecular Carcinogenesis ​57, no. 2 (2017): ​216​-224​. ​https://doi.org/10.1002/mc.22748.
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  • 2017 Journal Article
    ​ ​Li, Yafang, Xiangjun Xiao, Younghun Han, Olga Gorlova, David Qian, Natasha Leighl, Jakob S Johansen et al. "Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population​." ​Carcinogenesis ​39, no. 3 (2017): ​336​-346​. ​https://doi.org/10.1093/carcin/bgx113.
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  • 2017 Journal Article
    ​ ​Gu, Fangyi, Han Zhang, Paula L. Hyland, Sonja Berndt, Susan M. Gapstur, William Wheeler, the ELLIPSE consortium et al. "Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia​." ​International Journal of Cancer ​141, no. 9 (2017): ​1794​-1802​. ​https://doi.org/10.1002/ijc.30883.
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  • 2017 Journal Article
    ​ ​Amos, Christopher I., Joe Dennis, Zhaoming Wang, Jinyoung Byun, Fredrick R. Schumacher, Simon A. Gayther, Graham Casey et al. "The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers​." ​Cancer Epidemiology Biomarkers & Prevention ​26, no. 1 (2017): ​126​-135​. ​https://doi.org/10.1158/1055-9965.EPI-16-0106.
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  • 2017 Journal Article | 
    ​ ​Papiol, Sergi, Dejan Popovic, Daniel Keeser, Alkomiet Hasan, Thomas Schneider-Axmann, Franziska A. Degenhardt, Moritz J. Rossner et al. "Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia​." ​Translational Psychiatry ​7 (2017): ​e1159​. ​https://doi.org/10.1038/tp.2017.131.
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  • 2017 Journal Article | 
    ​ ​Carreras-Torres, Robert, Mattias Johansson, Philip C. Haycock, Kaitlin H. Wade, Caroline L. Relton, Richard M. Martin, George Davey Smith et al. "Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.​." ​PloS one ​12, no. 6 (2017): ​e0177875​. ​https://doi.org/10.1371/journal.pone.0177875.
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  • 2017 Journal Article | 
    ​ ​Feng, Yun, Y. Wang, Hongliang Liu, Zhensheng Liu, Coleman Mills, Younghun Han, Rayjean J. Hung et al. "Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium​." ​Scientific Reports ​7 (2017): ​825​. ​https://doi.org/10.1038/s41598-017-00850-0.
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  • 2017 Journal Article
    ​ ​Yin, Jieyun, Hongliang Liu, Zhensheng Liu, Kouros Owzar, Younghun Han, L. I. Su, Yongyue Wei et al. "Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus​." ​Molecular Carcinogenesis ​56, no. 6 (2017): ​1663​-1672​. ​https://doi.org/10.1002/mc.22622.
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  • 2017 Journal Article
    ​ ​Zhou, Fei, Y. Wang, Hongliang Liu, Neal Ready, Younghun Han, Rayjean J. Hung, Yonathan Brhane et al. "Susceptibility Loci of CNOT6 in the General mRNA Degradation Pathway and Lung Cancer Risk-A Re-Analysis of Eight GWASs​." ​Molecular Carcinogenesis ​56, no. 4 (2017): ​1227​-1238​. ​https://doi.org/10.1002/mc.22585.
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  • 2017 Journal Article
    ​ ​Liu, Hongliang, Zhensheng Liu, Y. Wang, Thomas E. Stinchcombe, Kouros Owzar, Younghun Han, Rayjean J. Hung et al. "Functional variants in DCAF4 associated with lung cancer risk in European populations​." ​Carcinogenesis ​38, no. 5 (2017): ​541​-551​. ​https://doi.org/10.1093/carcin/bgx033.
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  • 2017 Journal Article | 
    ​ ​Pan, Yongchu, Hongliang Liu, Y. Wang, Xiaozheng Kang, Zhensheng Liu, Kouros Owzar, Younghun Han et al. "Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs​." ​Scientific Reports ​7 (2017): ​44634​. ​https://doi.org/10.1038/srep44634.
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  • 2017 Journal Article | 
    ​ ​Rosenberger, Albert, Melanie Sohns, Stefanie Friedrichs, Rayjean J. Hung, Gord Fehringer, John R. McLaughlin, Christopher I. Amos et al. "Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus​." ​PLoS ONE ​12, no. 3 (2017): ​e0173339​. ​https://doi.org/10.1371/journal.pone.0173339.
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  • 2017 Journal Article | 
    ​ ​Friedrichs, Stefanie, Juliane Manitz, Patricia Burger, Christopher I. Amos, Angela Risch, Jenny Chang-Claude, Heinz-Erich Wichmann, Thomas Kneib, Heike Bickeböller, and Benjamin Hofner. "Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies​." ​Computational and mathematical methods in medicine ​2017 (2017): ​6742763​-17​. ​https://doi.org/10.1155/2017/6742763.
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  • 2016 Conference Paper
    ​ ​Mckay, James Dowling, Yafang Li, Younghun Han, Xiangjun Xioa, John Field, Xuchen Zong, Heike Bickeböller et al. "Abstract 2569: A genome wide association study of lung cancer identifies 11 novel susceptibility loci​." ​​2569​-2569. ​2016. https://doi.org/10.1158/1538-7445.AM2016-2569.
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  • 2016 Journal Article
    ​ ​Chen, Li-Shiun, Timothy Baker, Rayjean J. Hung, Amy Horton, Robert Culverhouse, Sarah Hartz, Nancy Saccone et al. "Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis​." ​EBioMedicine ​11 (2016): ​219​-226​. ​https://doi.org/10.1016/j.ebiom.2016.08.012.
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  • 2016 Journal Article | 
    ​ ​Malzahn, Dörthe, Stefanie Friedrichs, and Heike Bickeböller. "Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data​." ​BMC Proceedings ​10 (2016): ​17​. ​https://doi.org/10.1186/s12919-016-0042-9.
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  • 2016 Journal Article | 
    ​ ​Brenner, Darren R., P. C. Brennan, Paolo Boffetta, Christopher I. Amos, Margaret R. Spitz, Chu Chen, Gary Goodman et al. "Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls (vol 132, pg 579, 2013)​." ​Human Genetics ​135, no. 8 (2016): . ​https://doi.org/10.1007/s00439-016-1692-4.
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  • 2016 Journal Article | 
    ​ ​Khankari, Nikhil K., Xiao-Ou Shu, Wanqing Wen, Peter Kraft, Sara Lindstrom, Ulrike Peters, Joellen Schildkraut et al. "Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses​." ​PLoS Medicine ​13, no. 9 (2016): ​e1002118​. ​https://doi.org/10.1371/journal.pmed.1002118.
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  • 2016 Journal Article
    ​ ​Wang, L., Hongliang Liu, Zhensheng Liu, Xiaohua Yi, Heike Bickeboller, Rayjean J. Hung, P. C. Brennan et al. "Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium​." ​Carcinogenesis ​37, no. 9 (2016): ​888​-896​. ​https://doi.org/10.1093/carcin/bgw070.
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  • 2016 Journal Article | 
    ​ ​Yuan, Hua, Hongliang Liu, Zhensheng Liu, Kouros Owzar, Younghun Han, L. I. Su, Yongyue Wei et al. "A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer​." ​Scientific Reports ​6 (2016): ​34234​. ​https://doi.org/10.1038/srep34234.
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  • 2016 Journal Article
    ​ ​Kang, Xiaozheng, Hongliang Liu, Mark W. Onaitis, Zhensheng Liu, Kouros Owzar, Younghun Han, L. I. Su et al. "Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls​." ​Carcinogenesis ​37, no. 3 (2016): ​280​-289​. ​https://doi.org/10.1093/carcin/bgw014.
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  • 2016 Journal Article | Overview | 
    ​ ​Isernhagen, Antje, Doerthe Malzahn, Heike Bickeboeller, and Ralf Dressel. "Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks​." ​Frontiers in Immunology ​7 (2016): ​588​. ​https://doi.org/10.3389/fimmu.2016.00588.
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  • 2016 Journal Article
    ​ ​Pearce, Kim F., Yesilda Balavarca, J. Norden, Graham H. Jackson, Ernst Holler, Ralf Dressel, Hildegard T. Greinix et al. "Impact of genomic risk factors on survival after haematopoietic stem cell transplantation for patients with acute leukaemia​." ​International Journal of Immunogenetics ​43, no. 6 (2016): ​404​-412​. ​https://doi.org/10.1111/iji.12295.
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  • 2016 Journal Article
    ​ ​Patel, Yesha M., Sunghim L. Park, Younghun Han, Lynne R. Wilkens, Heike Bickeböller, Albert Rosenberger, Neil Caporaso et al. "Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk​." ​Cancer Research ​76, no. 19 (2016): ​5768​-5776​. ​https://doi.org/10.1158/0008-5472.CAN-16-0446.
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  • 2015 Journal Article
    ​ ​Hung, Rayjean J., Cornelia M. Ulrich, Ellen L. Goode, Yonathan Brhane, Kenneth Muir, Andrew T. Chan, Loic Le Marchand et al. "Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer​." ​JNCI Journal of the National Cancer Institute ​107, no. 11 (2015): ​djv246​. ​https://doi.org/10.1093/jnci/djv246.
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  • 2015 Conference Abstract
    ​ ​Friedrichs, Stefanie, Christopher I. Amos, P. C. Brennan, David Christiani, Rayjean J. Hung, Angela Risch, Irene Brueske et al. "Kernel-based Pathway Meta-Analysis in ILCCO / TRICL Genome-wide Association Studies​." ​Genetic Epidemiology ​39​, ​no. 7 (2015): 
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  • 2015 Conference Abstract
    ​ ​Wei, Qingyi, Hongliang Liu, Zhensheng Liu, Christopher I. Amos, Jennifer Anne Doherty, Heike Bickeboller, Rayjean J. Hung et al. "A novel variant in DNA repair gene GTF2H4 is associated with lung cancer risk: A reanalysis of GWAS datasets from the TRICL consortium​." ​Cancer Research ​75​ ​(2015): https://doi.org/10.1158/1538-7445.AM2015-4597.
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  • 2015 Journal Article
    ​ ​Brenner, Darren R., Christopher I. Amos, Yonathan Brhane, Maria N. Timofeeva, Neil Caporaso, Yufei Wang, David C. Christiani et al. "Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia​." ​Carcinogenesis ​36, no. 11 (2015): ​1314​-1326​. ​https://doi.org/10.1093/carcin/bgv128.
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  • 2015 Review
    ​ ​Chen, Li-Shiun, Rayjean J. Hung, Timothy Baker, Amy Horton, Rob Culverhouse, Nancy Saccone, Iona Cheng et al. "CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis-A Meta-Analysis​." JNCI Journal of the National Cancer Institute ​107​, no. 5​ (2015): ​djv100​. ​https://doi.org/10.1093/jnci/djv100.
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  • 2015 Conference Abstract
    ​ ​Rosenberger, Albert, Stefanie Friedrichs, Christopher I. Amos, P. C. Brennan, Gordon Fehringer, Irene Brueske, Rayjean J. Hunh, Martina Mueller-Nurasyid, Angela Risch, and Heike Bickeboeller. "Meta-analysis of gene-set analyses based on genome wide association studies, method development and application within ILCCO/TRICL consortia​." ​Genetic Epidemiology ​39​, ​no. 7 (2015): 
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  • 2015 Journal Article | 
    ​ ​Zhang, C., Jennifer Anne Doherty, Stephen Burgess, Rayjean J. Hung, Sara Lindstroem, Peter Kraft, Jian Gong et al. "Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study​." ​Human Molecular Genetics ​24, no. 18 (2015): ​5356​-5366​. ​https://doi.org/10.1093/hmg/ddv252.
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  • 2015 Journal Article | 
    ​ ​Hancock, D. B., G. W. Reginsson, N. C. Gaddis, X. Chen, N. L. Saccone, S. M. Lutz, B. Qaiser et al. "Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence​." ​Translational Psychiatry ​5 (2015): ​e651​. ​https://doi.org/10.1038/tp.2015.149.
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  • 2015 Journal Article
    ​ ​Qian, David C., Jinyoung Byun, Younghun Han, Casey S. Greene, John K. Field, Rayjean J. Hung, Yonathan Brhane et al. "Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions​." ​Human Molecular Genetics ​24, no. 25 (2015): ​7406​-7420​. ​https://doi.org/10.1093/hmg/ddv440.
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  • 2015 Journal Article | 
    ​ ​Rosenberger, Albert, Stefanie Friedrichs, Christopher I. Amos, P. C. Brennan, Gordon Fehringer, Joachim Heinrich, Rayjean J. Hung et al. "META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies​." ​PLoS ONE ​10, no. 10 (2015): ​e0140179​. ​https://doi.org/10.1371/journal.pone.0140179.
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  • 2015 Journal Article
    ​ ​Poirier, Julia G., P. C. Brennan, James D. McKay, Margaret R. Spitz, Heike Bickeboeller, Angela Risch, Geoffrey Liu et al. "Informed Genome-Wide Association Analysis With Family History As a Secondary Phenotype Identifies Novel Loci of Lung Cancer​." ​Genetic Epidemiology ​39, no. 3 (2015): ​197​-206​. ​https://doi.org/10.1002/gepi.21882.
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  • 2015 Journal Article
    ​ ​Balavarca, Yesilda, Kim F. Pearce, J. Norden, M. Collin, Graham H. Jackson, Ernst Holler, Ralf Dressel et al. "Predicting survival using clinical risk scores and non-HLA immunogenetics​." ​Bone Marrow Transplantation ​50, no. 11 (2015): ​1445​-1452​. ​https://doi.org/10.1038/bmt.2015.173.
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  • 2015 Journal Article | Research Paper | 
    ​ ​Isernhagen, Antje, Doerthe Malzahn, Elena Viktorova, Leslie Elsner, Sebastian Monecke, Frederike von Bonin, Markus Kilisch et al. "The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation​." ​EMBO Molecular Medicine ​7, no. 11 (2015): ​1480​-1502​. ​https://doi.org/10.15252/emmm.201505246.
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  • 2014 Conference Paper
    ​ ​Brenner, Darren R., Paolo Boffetta, Eric J. Duell, Heike Bickeböller, Albert Rosenberger, Joshua E. Muscat, Ping Yang et al. "Abstract 4826: International Lung Cancer Consortium: Pooled analysis of previous lung diseases and lung cancer risk​." ​​4826​-4826. ​2014. https://doi.org/10.1158/1538-7445.AM10-4826.
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  • 2014 Journal Article | 
    ​ ​Park, S. L., Megan D. Fesinmeyer, Maria N. Timofeeva, Christian P. Caberto, Jonathan M. Kocarnik, Younghun Han, Shelly-Ann Love et al. "Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia​." ​JNCI Journal of the National Cancer Institute ​106, no. 4 (2014): ​dju061​. ​https://doi.org/10.1093/jnci/dju061.
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  • 2014 Journal Article | 
    ​ ​Ngoc-Thuy Ha, Ngoc-Thuy Ha, Saskia Freytag, and Heike Bickeboeller. "Coverage and efficiency in current SNP chips​." ​European Journal of Human Genetics ​22, no. 9 (2014): ​1124​-1130​. ​https://doi.org/10.1038/ejhg.2013.304.
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  • 2014 Journal Article
    ​ ​Freytag, Saskia, and Heike Bickeboeller. "Comparison of three summary statistics for ranking genes in genome-wide association studies​." ​Statistics in Medicine ​33, no. 11 (2014): ​1828​-1841​. ​https://doi.org/10.1002/sim.6063.
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  • 2014 Journal Article | 
    ​ ​Freytag, Saskia, Juliane Manitz, Martin Schlather, Thomas Kneib, Christopher I. Amos, Angela Risch, Jenny Chang-Claude, Joachim Heinrich, and Heike Bickeböller. "A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies​." ​Human Heredity ​76, no. 2 (2014): ​64​-75​. ​https://doi.org/10.1159/000357567.
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  • 2014 Journal Article
    ​ ​Hornhardt, Sabine, Ute Roessler, Wiebke Sauter, Albert Rosenberger, Thomas Illig, Heike Bickeboeller, Hans-Erich Wichmann, and Maria Gomolka. "Genetic factors in individual radiation sensitivity​." ​DNA Repair ​16 (2014): ​54​-65​. ​https://doi.org/10.1016/j.dnarep.2014.02.001.
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  • 2014 Journal Article | 
    ​ ​Malzahn, Doerthe, Martina Mueller-Nurasyid, Iris M. Heid, H-Erich Wichmann, and Heike Bickeboeller. "Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R​." ​European Journal of Human Genetics ​22, no. 10 (2014): ​1217​-1224​. ​https://doi.org/10.1038/ejhg.2014.3.
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  • 2013 Journal Article | Letter Note
    ​ ​Bickeboeller, Heike, R. Haux, and Aurelia Winter. ""Tradition Is not Preserving the Ashes, It Is Passing on the Fire" On Strengthening Ties with GMDS​." ​METHODS OF INFORMATION IN MEDICINE ​52, no. 1 (2013): ​1​-2​. ​
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  • 2013 Journal Article
    ​ ​Sohns, Melanie, Elena Viktorova, Christopher I. Amos, P. C. Brennan, Gord Fehringer, Valerie Gaborieau, Younghun Han et al. "Empirical Hierarchical Bayes Approach to Gene-Environment Interactions: Development and Application to Genome-Wide Association Studies of Lung Cancer in TRICL​." ​Genetic Epidemiology ​37, no. 6 (2013): ​551​-559​. ​https://doi.org/10.1002/gepi.21741.
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  • 2013 Journal Article | 
    ​ ​Freytag, Saskia, Heike Bickeböller, Christopher I. Amos, Thomas Kneib, and Martin Schlather. "A Novel Kernel for Correcting Size Bias in the Logistic Kernel Machine Test with an Application to Rheumatoid Arthritis​." ​Human Heredity ​74, no. 2 (2013): ​97​-108​. ​https://doi.org/10.1159/000347188.
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  • 2013 Journal Article | 
    ​ ​Kästner, Anne, Dörte Malzahn, Martin Begemann, Constanze Hilmes, Heike Bickeböller, and Hannelore Ehrenreich. "Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters​." ​BMC Psychiatry ​13 (2013): ​218​. ​https://doi.org/10.1186/1471-244X-13-218.
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  • 2013 Journal Article
    ​ ​Brenner, Darren R., P. C. Brennan, Paolo Boffetta, Christopher I. Amos, Margaret R. Spitz, Chu Chen, Gary Goodman et al. "Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls​." ​Human Genetics ​132, no. 5 (2013): ​579​-589​. ​https://doi.org/10.1007/s00439-013-1270-y.
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  • 2012 Conference Abstract
    ​ ​Viktorova, Elena, Doerthe Malzahn, Yesilda Balavarca, Antje Isernhagen, Frederike von Bonin, Janne Michael, Gerald Wulf, Dieter Kube, Ralf Dressel, and Heike Bickeboeller. "Association of MICA-129 genotype with common risks of hematopoietic stem cell transplantation (HSCT)​." ​Annals of Human Genetics ​76​ ​(2012): 
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  • 2012 Conference Abstract
    ​ ​Viktorova, Elena, Melanie Sohns, and Heike Bickeboller. "Impact of Population Stratification on Gene-Environment Interaction Analysis​." ​Genetic Epidemiology ​36​, ​no. 2 (2012): 
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  • 2012 Conference Abstract
    ​ ​Malzahn, Doerthe, Martina Mueller-Nurasyid, Iris M. Heid, H-Erich Wichmann, and Heike Bickeboeller. "Inconsistent marginal association of INSIG2 with body mass index may be explained by gene-time and gene-gene interactions​." ​Annals of Human Genetics ​76​ ​(2012): 
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  • 2012 Journal Article
    ​ ​Freytag, S., C. I. Amos, H. Bickeböller, Thomas Kneib, and M. Schlather. "Novel Kernel for Correcting Significance Bias in the Logistic Kernel Machine Test with an Application to Rheumatoid Arthritis​." ​Human Heredity ​74 (2012): ​97​-108​. ​
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  • 2012 Conference Abstract
    ​ ​Sohns, Melanie, Elena Viktorova, Gord Fehringer, Valerie Gaborieau, Younghun Han, Jenny Chang-Claude, Joachim Heinrich et al. "Application of the Empirical Hierarchical Bayes Approach for Gene-Environment Interaction to TRICL Lung Cancer GWAS​." ​Genetic Epidemiology ​36​, ​no. 7 (2012): 
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  • 2012 Conference Abstract
    ​ ​Viktorova, Elena, Melanie Sohns, and Heike Bickeboeller. "Principal Component Analysis Corrects for Population Stratification in Studies of Gene-Environment Interactions​." ​Genetic Epidemiology ​36​, ​no. 7 (2012): 
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  • 2012 Conference Abstract
    ​ ​Freytag, Saskia, Christopher I. Amos, Heike Bickeböller, Thomas Kneib, and Martin Schlather. "Novel Kernel Function in the Logistic Kernel Machine Test for Pathways in GWA Studies​." ​Genetic Epidemiology ​36​, ​no. 7 (2012): 
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  • 2012 Conference Abstract
    ​ ​Kaestner, Anne, Doerthe Malzahn, Heike Bickeboeller, and Hannelore Ehrenreich. "Introducing ORNI, the 'Odor Recognition, Naming and Interpretation Test', a Simple and Specific Measure of Sensory-Cognitive-Emotional Processing in Schizophrenia​." ​Biological Psychiatry ​71​, ​no. 8 (2012): 
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  • 2012 Conference Abstract
    ​ ​Balavarca, Yesilda, and Heike Bickeboeller. "Assessing prediction error of genetic variants in Cox regression models​." ​Annals of Human Genetics ​76​ ​(2012): ​419​-420. 
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  • 2012 Conference Abstract
    ​ ​Ngoc-Thuy Ha, Ngoc-Thuy Ha, Saskia Freytag, and Heike Bickeboeller. "Coverage in current SNP chips​." ​Annals of Human Genetics ​76​ ​(2012): 
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  • 2012 Conference Abstract
    ​ ​Freytag, Saskia, and Heike Bickeboeller. "Comparison of three gene summary statistics for gene rankings in genome-wide association studies​." ​Annals of Human Genetics ​76​ ​(2012): 
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  • 2012 Journal Article
    ​ ​Rosenberger, Albert, Heike Bickeboeller, Valerie McCormack, Darren R. Brenner, Eric J. Duell, Anne Tjonneland, Soren Friis et al. "Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium​." ​Carcinogenesis ​33, no. 3 (2012): ​587​-597​. ​https://doi.org/10.1093/carcin/bgr307.
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  • 2012 Journal Article | 
    ​ ​Fehringer, Gordon, Geoffrey Liu, Laurent Briollais, P. C. Brennan, Christopher I. Amos, Margaret R. Spitz, Heike Bickeboeller, Heinz-Erich Wichmann, Angela Risch, and Rayjean J. Hung. "Comparison of Pathway Analysis Approaches Using Lung Cancer GWAS Data Sets​." ​PLoS ONE ​7, no. 2 (2012): ​e31816​. ​https://doi.org/10.1371/journal.pone.0031816.
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  • 2012 Journal Article | 
    ​ ​Timofeeva, Maria N., Rayjean J. Hung, Thorunn Rafnar, David C. Christiani, John K. Field, Heike Bickeboeller, Angela Risch et al. "Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls​." ​Human Molecular Genetics ​21, no. 22 (2012): ​4980​-4995​. ​https://doi.org/10.1093/hmg/dds334.
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  • 2012 Review
    ​ ​Brenner, Darren R., Paolo Boffetta, Eric J. Duell, Heike Bickeboeller, Albert Rosenberger, Valerie McCormack, Joshua E. Muscat et al. "Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium​." American Journal of Epidemiology ​176​, no. 7​ (2012): ​573​-585​. ​https://doi.org/10.1093/aje/kws151.
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  • 2012 Journal Article | 
    ​ ​Zaitlen, Noah, Sara Lindstroem, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton et al. "Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies​." ​PLoS Genetics ​8, no. 11 (2012): ​e1003032​. ​https://doi.org/10.1371/journal.pgen.1003032.
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  • 2012 Journal Article | 
    ​ ​Rosenberger, Albert, Ute Roessler, Sabine Hornhardt, Wiebke Sauter, Heike Bickeboeller, H-Erich Wichmann, and Maria Gomolka. "Heritability of Radiation Response in Lung Cancer Families​." ​Genes ​3, no. 2 (2012): ​248​-260​. ​https://doi.org/10.3390/genes3020248.
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  • 2012 Journal Article
    ​ ​Cote, Michele L., Mei Liu, Stefano Bonassi, Monica Neri, Ann G. Schwartz, David C. Christiani, Margaret R. Spitz et al. "Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium​." ​European Journal of Cancer ​48, no. 13 (2012): ​1957​-1968​. ​https://doi.org/10.1016/j.ejca.2012.01.038.
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  • 2011 Journal Article | 
    ​ ​Ghosh, Saurabh, Heike Bickeböller, Julia Bailey, Joan E. Bailey-Wilson, Rita Cantor, Robert Culverhouse, Warwick Daw et al. "Identifying rare variants from exome scans: the GAW17 experience​." ​BMC Proceedings ​5, no. Suppl 9 (2011): ​S1​. ​https://doi.org/10.1186/1753-6561-5-S9-S1.
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  • 2011 Journal Article | 
    ​ ​McCormack, Valerie A., Rayjean J. Hung, Darren R. Brenner, Heike Bickeboeller, Albert Rosenberger, Joshua E. Muscat, Philip Lazarus et al. "Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO)​." ​Cancer Causes & Control ​22, no. 12 (2011): ​1709​-1720​. ​https://doi.org/10.1007/s10552-011-9847-z.
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  • 2011 Journal Article
    ​ ​Rosenberger, Albert, Ute Roessler, Sabine Hornhardt, Wiebke Sauter, Heike Bickeboeller, Heinz-Erich Wichmann, and Maria Gomolka. "Validation of a fully automated COMET assay: 1.75 million single cells measured over a 5 year period​." ​DNA Repair ​10, no. 3 (2011): ​322​-337​. ​https://doi.org/10.1016/j.dnarep.2010.12.003.
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  • 2011 Journal Article | 
    ​ ​Papiol, Sergi, Dörte Malzahn, Anne Kästner, Swetlana Sperling, Martin Begemann, Hreinn Stefansson, Heike Bickeböller, Klaus-Armin Nave, and Hannelore Ehrenreich. "Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia​." ​Translational Psychiatry ​1, no. 10 (2011): ​e45​. ​https://doi.org/10.1038/tp.2011.43.
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  • 2011 Journal Article | Research Paper | 
    ​ ​Grube, Sabrina, Martin F. Gerchen, Bartosz Adamcio, Luis A. Pardo, Sabine Martin, Dörthe Malzahn, Sergi Papiol et al. "A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia​." ​EMBO Molecular Medicine ​3, no. 6 (2011): ​309​-319​. ​https://doi.org/10.1002/emmm.201100135.
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  • 2011 Journal Article
    ​ ​Bickeboeller, Heike, Jeanine J. Houwing-Duistermaat, X. Wang, and X. Yan. "Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction​." ​Genetic Epidemiology ​35 (2011): ​S35​-S40​. ​https://doi.org/10.1002/gepi.20647.
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  • 2010 Conference Abstract
    ​ ​Sohns, Melanie, Juan Pablo Lewinger, Heike Bickeboller, and Duncan C. Thomas. "An Efficient Test of Gene-Environment Interaction for Genomewide Association Studies​." ​Genetic Epidemiology ​34​, ​no. 8 (2010): ​920​-921. 
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  • 2010 Conference Abstract
    ​ ​Dickinson, Anne M., Kim F. Pearce, Graham H. Jackson, M. Collin, J. Norden, Ernst Holler, Hildegard T. Greinix et al. "Clinical and genetic risk assessment for overall survival in haematopoietic stem cell transplantation​." ​Bone Marrow Transplantation ​45​ ​(2010): 
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  • 2010 Conference Abstract
    ​ ​Klaus, Sabrina, Martin Begemann, Sergi Papiol, Doerthe Malzahn, Heidi Friedrichs, Katja Ribbe, Ahmed El-Kordi et al. "Complexin2 Gene Polymorphisms Modify Cognitive Performance in Schizophrenia​." ​Schizophrenia Research ​117​, ​no. 2-3 (2010): ​337​-338. 
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  • 2010 Journal Article | 
    ​ ​Begemann, Martin, Sabrina Grube, Sergi Papiol, Dörte Malzahn, Henning Krampe, Katja Ribbe, Heidi Friedrichs et al. "Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms​." ​Archives of General Psychiatry ​67, no. 9 (2010): ​879​-888​. ​https://doi.org/10.1001/archgenpsychiatry.2010.107.
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  • 2010 Journal Article | 
    ​ ​Truong, T., R. J. Hung, Christopher I. Amos, X. Wu, H. Bickeböller, A. Rosenberger, W. Sauter et al. "Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium​." ​JNCI Journal of the National Cancer Institute ​102, no. 13 (2010): ​959​-971​. ​https://doi.org/10.1093/jnci/djq178.
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  • 2010 Journal Article
    ​ ​Ghebremedhin, Estifanos, Albert Rosenberger, Udo Rueb, Mario Vuksic, Tzeggai Berhe, Heike Bickeboeller, Rob A. I. de Vos, Dietmar Rudolf Thal, and Thomas Deller. "Inverse Relationship Between Cerebrovascular Lesions and Severity of Lewy Body Pathology in Patients With Lewy Body Diseases​." ​Journal of Neuropathology & Experimental Neurology ​69, no. 5 (2010): ​442​-448​. ​https://doi.org/10.1097/NEN.0b013e3181d88e63.
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  • 2010 Journal Article
    ​ ​Timofeeva, Maria N., Silke Kropp, Wiebke Sauter, Lars Beckmann, Albert Rosenberger, Thomas Illig, Birgit Jaeger et al. "Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer​." ​International Journal of Cancer ​127, no. 7 (2010): ​1547​-1561​. ​https://doi.org/10.1002/ijc.25175.
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  • 2010 Journal Article | Letter Note
    ​ ​Landi, Maria Teresa, Nilanjan Chatterjee, Neil E. Caporaso, Melissa Rotunno, Demetrius Albanes, Michael Thun, William Wheeler et al. "GPC5 rs2352028 variant and risk of lung cancer in never smokers​." ​The Lancet Oncology ​11, no. 8 (2010): ​714​-716​. ​https://doi.org/10.1016/S1470-2045(10)70096-6.
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  • 2010 Journal Article
    ​ ​Elsner, Leslie, Jingky P. Lozano, Vijayakumar Muppala, Britta Eiz-Vesper, Sara Y. Demiroglu, Doerthe Malzahn, Thomas R. Herrmann et al. "The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells​." ​Journal of Cellular and Molecular Medicine ​14, no. 4 (2010): ​992​-1002​. ​https://doi.org/10.1111/j.1582-4934.2008.00677.x.
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  • 2010 Journal Article | Research Paper
    ​ ​Knöll, Ralph, Sawa Kostin, Stefanie Klede, Kostas Savvatis, Lars Klinge, Ina Stehle, Sylvia Gunkel et al. "A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy​." ​Circulation Research ​106, no. 4 (2010): ​695​-704​. ​https://doi.org/10.1161/CIRCRESAHA.109.206243.
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  • 2010 Journal Article | Research Paper
    ​ ​Radyushkin, Konstantin, Ahmed El-Kordi, Susann Boretius, S. Castaneda, Anja Ronnenberg, Kerstin Reim, H. Bickeböller, Jens Frahm, N. Brose, and Hanhelore Ehrenreich. "Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia​." ​Genes, Brain and Behavior ​9, no. 6 (2010): ​592​-602​. ​https://doi.org/10.1111/j.1601-183X.2010.00590.x.
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  • 2010 Journal Article | 
    ​ ​Dickinson, Anne M., Kim F. Pearce, Jean Norden, Stephen G. O'Brien, Ernst Holler, Heike Bickeboeller, Yesilda Balavarca et al. "Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia​." ​HAEMATOLOGICA-THE HEMATOLOGY JOURNAL ​95, no. 6 (2010): ​922​-927​. ​https://doi.org/10.3324/haematol.2009.016220.
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  • 2010 Journal Article | 
    ​ ​Malzahn, D., Arne Schillert, M. Mueller, and Heike Bickeboeller. "The Longitudinal Nonparametric Test as a New Tool to Explore Gene-Gene and Gene-Time Effects in Cohorts​." ​Genetic Epidemiology ​34, no. 5 (2010): ​469​-478​. ​https://doi.org/10.1002/gepi.20500.
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  • 2010 Journal Article
    ​ ​Truong, Therese, Wiebke Sauter, James D. McKay, H. Dean, III Hosgood, Carla Gallagher, Christopher I. Amos, Margaret R. Spitz et al. "International Lung Cancer Consortium: Coordinated association study of 10 potential lung cancer susceptibility variants​." ​Carcinogenesis ​31, no. 4 (2010): ​625​-633​. ​https://doi.org/10.1093/carcin/bgq001.
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  • 2009 Conference Abstract
    ​ ​Fae, Ingrid, Yesilda Balavarca, Heike Bickeboller, Katarina Ludajic, Agathe Rosenmayr, Gottfried F. Fischer, Peter Kalhs, and Hildegard T. Greinix. "ABO minor mismatches represent risk factors for acute graft-versus-host disease in hematopoietic stem cell transplant patients​." ​Tissue Antigens ​73​, ​no. 5 (2009): 
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  • 2009 Conference Abstract
    ​ ​Landi, Maria, Nilanjan Chatterjee, Kai Yu, Kevin Jacobs, Andrew W. Bergen, Lynn R. Goldin, Alisa M. Goldstein et al. "A comprehensive genome-wide association study of lung cancer​." ​Cancer Research ​69​ ​(2009): 
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  • 2009 Conference Abstract
    ​ ​Fischer, Gottfried F., Yesilda Balavarca, Heike Bickeboeller, Agathe Rosenmayr, Katarina Ludajic, Ingrid Fae, Sabine Wenda, Peter Kalhs, and Hildegard T. Greinix. "HLA-E polymorphism is associated with the outcome of hematopoietic stem cell transplantation with unrelated donors​." ​Tissue Antigens ​73​, ​no. 5 (2009): 
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  • 2009 Conference Abstract
    ​ ​Katarina, Ludajic, Gottfried F. Fischer, Yesilda Balavarca, Heike Bickeboeller, Agathe Rosenmayr, Ingrid Fae, Peter Kalhs, and Hildegard T. Greinix. "KIR genes and KIR ligands effect occurrence of acute GvHD in HLA matched, hematopoietic stem cell transplant patients​." ​Tissue Antigens ​73​, ​no. 5 (2009): 
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  • 2009 Conference Abstract
    ​ ​Dickinson, Anne M., Kim F. Pearce, Graham H. Jackson, Matthew Collin, Jean Norden, Ernst Holler, Heike Bickeboller et al. "Clinical and Genetic Risk Assessment for Overall Survival in Haematopoietic Stem Cell Transplantation (HSCT).​." ​Blood ​114​, ​no. 22 (2009): ​488​-489. 
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  • 2009 Journal Article | 
    ​ ​Malzahn, Dörthe, Yesilda Balavarca, Jingky P Lozano, and Heike Bickeböller. "Tests for candidate-gene interaction for longitudinal quantitative traits measured in a large cohort​." ​BMC Proceedings ​3, no. S7 (2009): . ​https://doi.org/10.1186/1753-6561-3-S7-S80.
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  • 2009 Journal Article | Research Paper | 
    ​ ​Sohns, Melanie, Albert Rosenberger, and Heike Bickeböller. "Integration of a priori gene set information into genome-wide association studies​." ​BMC Proceedings ​3, no. Suppl 7 (2009): ​S95​. ​https://doi.org/10.1186/1753-6561-3-S7-S95.
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  • 2009 Journal Article | Research Paper | 
    ​ ​Cupples, L. A., Joseph Beyene, Heike Bickeböller, E. W. Daw, M. D. Fallin, W. J. Gauderman, Saurabh Ghosh et al. "Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses​." ​BMC Proceedings ​3, no. Suppl 7 (2009): ​S1​. ​https://doi.org/10.1186/1753-6561-3-S7-S1.
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  • 2009 Journal Article
    ​ ​Timofeeva, Maria N., Silke Kropp, Wiebke Sauter, Lars Beckmann, Albert Rosenberger, Thomas Illig, Birgit Jaeger et al. "CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences​." ​Carcinogenesis ​30, no. 7 (2009): ​1161​-1169​. ​https://doi.org/10.1093/carcin/bgp102.
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  • 2009 Journal Article
    ​ ​Landi, Maria Teresa, Nilanjan Chatterjee, Kai Yu, Lynn R. Goldin, Alisa M. Goldstein, Melissa Rotunno, Lisa Mirabello et al. "A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma​." ​The American Journal of Human Genetics ​85, no. 5 (2009): ​679​-691​. ​https://doi.org/10.1016/j.ajhg.2009.09.012.
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  • 2009 Journal Article | Letter Note
    ​ ​Ludajic, Katarina, Agathe Rosenmayr, I. Fae, Gottfried F. Fischer, Yesilda Balavarca, Heike Bickeboeller, Peter Kalhs, and Hildegard T. Greinix. "Association of HLA-E Polymorphism With the Outcome of Hematopoietic Stem-Cell Transplantation With Unrelated Donors​." ​Transplantation Journal ​88, no. 10 (2009): ​1227​-1228​. ​https://doi.org/10.1097/TP.0b013e3181bbb8fe.
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  • 2009 Journal Article
    ​ ​Ludajic, Katarina, Yesilda Balavarca, Heike Bickeboeller, Agathe Rosenmayr, I. Fae, Gottfried F. Fischer, Michal Kouba, David Pohlreich, Peter Kalhs, and Hildegard T. Greinix. "KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation​." ​Bone Marrow Transplantation ​44, no. 2 (2009): ​97​-103​. ​https://doi.org/10.1038/bmt.2008.432.
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  • 2009 Conference Paper | 
    ​ ​Tintle, Nathan, Francesca Lantieri, Jeremie Lebrec, Melanie Sohns, David Ballard, and Heike Bickeboeller. "Inclusion of A Priori Information in Genome-Wide Association Analysis​." ​Genetic Epidemiology ​33​ ​(2009): ​S74​-S80. https://doi.org/10.1002/gepi.20476.
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  • 2009 Journal Article
    ​ ​Ludajic, Katarina, Yesilda Balavarca, Heike Bickeboeller, Agathe Rosenmayr, Gottfried F. Fischer, Ingrid Fae, Peter Kalhs et al. "Minor ABO-Mismatches are Risk Factors for Acute Graft-versus-Host Disease in Hematopoietic Stem Cell Transplant Patients​." ​Biology of Blood and Marrow Transplantation ​15, no. 11 (2009): ​1400​-1406​. ​https://doi.org/10.1016/j.bbmt.2009.07.002.
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  • 2009 Journal Article | 
    ​ ​Mertens, Jasmin, Rusudan Bregadze, Ashham Mansur, Eva Askar, Heike Bickeboeller, Giuliano Ramadori, and Sabine Mihm. "Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity​." ​Journal of Molecular Medicine ​87, no. 8 (2009): ​815​-824​. ​https://doi.org/10.1007/s00109-009-0479-7.
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  • 2009 Journal Article | 
    ​ ​Ripatti, Samuli, Tim Becker, Heike Bickeboeller, Annica Dominicus, Christine Fischer, Keith Humphreys, Gudrun Jonasdottir et al. "GENESTAT: an information portal for design and analysis of genetic association studies​." ​European Journal of Human Genetics ​17, no. 4 (2009): ​533​-536​. ​https://doi.org/10.1038/ejhg.2008.216.
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  • 2009 Journal Article
    ​ ​Timofeeva, Maria N., Birgit Jaeger, Albert Rosenberger, Wiebke Sauter, Heinz-Erich Wichmann, Heike Bickeboeller, and Angela Risch. "A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers​." ​Clinical Biochemistry ​42, no. 6 (2009): ​500​-509​. ​https://doi.org/10.1016/j.clinbiochem.2008.12.011.
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  • 2008 Conference Abstract
    ​ ​Malzahn, D., Arne Schillert, M. Mueller, Iris M. Heid, Heinz-Erich Wichmann, and Heike Bickeboeller. "Gene-gene and gene-time effects in cohorts: Simulation study of a nonparametric longitudinal approach and results on real data​." ​Genetic Epidemiology ​32​, ​no. 7 (2008): 
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  • 2008 Conference Abstract
    ​ ​Ludajic, Katarina, Yesilda Balavarca, Heike Bickeboeller, David Pohlreich, Michal Kouba, Gottfried F. Fischer, I. Fae, Peter Kalhs, and Hildegard T. Greinix. "KIR/HLA interactions influence the outcome of haematopoietic stem cell transplantation​." ​Bone Marrow Transplantation ​41​ ​(2008): 
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  • 2008 Conference Abstract
    ​ ​Fischer, Gottfried F., Katarina Ludajic, Yesilda Balavarca, Heike Bickeboeller, David Pohlreich, Michal Kouba, Marie Dobrovolna et al. "Impact of HLA-DPB1 allelic and single amino acid mismatches on haematopoietic stem cell transplantation outcomes​." ​Bone Marrow Transplantation ​41​ ​(2008): 
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  • 2008 Conference Abstract
    ​ ​Fischer, Gottfried F., Katarina Ludajic, Yesilda Balavarca, Heike Bickeboeller, David Pohlreich, Michal Kouba, Milena Vrana et al. "HLA-DPB1 allellic and single amino acid mismatches effect HSCT outcome​." ​Tissue Antigens ​71​, ​no. 4 (2008): ​314​-315. 
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  • 2008 Conference Abstract
    ​ ​Balavarca, Yesilda, Ludajic Ludajic, Bickeboeller Bickeboeller, Pohlreich Pohlreich, Kouba Kouba, Dobrovolna Dobrovolna, Vrana Vrana et al. "Impact of HLA-DPB1 mismatches on Hematopoietic Stem Cell Transplantation (HSCT)​." ​Genetic Epidemiology ​32​, ​no. 7 (2008): 
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  • 2008 Conference Abstract
    ​ ​Lozano, Jingky P., and Heike Bickeboeller. "Detecting Epistasis among Candidate Genes using Quantitative Traits and Family Trios​." ​Genetic Epidemiology ​32​, ​no. 7 (2008): 
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  • 2008 Conference Abstract
    ​ ​Elsner, Leslie, Perris F. Fluegge, Jingky P. Lozano, Vijayakumar Muppala, Sara Yasemin Demiroglu, D. Malzahn, Heike Bickeboeller, Gabriele Multhoff, L. Walter, and Ralf Dressel. "The stress-inducible endogenous danger signals HSP70 and MICA synergistically activate the cytotoxic effector functions of human NK cells​." ​Wiener klinische Wochenschrift ​120​ ​(2008): 
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  • 2008 Journal Article
    ​ ​Sauter, Wiebke, Albert Rosenberger, Lars Beckmann, Silke Kropp, Kirstin Mittelstrass, Maria N. Timofeeva, Gabi Woelke et al. "Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer​." ​Cancer Epidemiology Biomarkers & Prevention ​17, no. 5 (2008): ​1127​-1135​. ​https://doi.org/10.1158/1055-9965.EPI-07-2840.
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  • 2008 Conference Abstract
    ​ ​Timofeeva, Maria N., Silke Kropp, Wiebke Sauter, Albert Rosenberger, Thomas Illig, Hendrik Dienemann, Heike Bickeboeller, Jenny Chang-Claude, Angela Risch, and Heinz-Erich Wichmann. "Genetic polymorphisms of myeloperoxidase (MPO), epoxide hydrolase 1 (EPHX1) and NAD(P)H dehydrogenase 1 (NQO1) as risk factors of early onset lung caner​." ​EJC SUPPLEMENTS ​6​, ​no. 9 (2008): https://doi.org/10.1016/S1359-6349(08)71905-0.
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  • 2008 Conference Abstract
    ​ ​Sauter, Wiebke, Albert Rosenberger, L. Beckmann, Maria N. Timofeeva, Kirstin Mittelstrass, Thomas Illig, Jenny Chang-Claude, Heinz-Erich Wichmann, Heike Bickeboeller, and Angela Risch. "Case-control study of genetic susceptibility in early onset lung cancer: Investigation of Matrix Metalloproteinase-1 (MMP1)​." ​EJC SUPPLEMENTS ​6​, ​no. 9 (2008): https://doi.org/10.1016/S1359-6349(08)71903-7.
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  • 2008 Conference Abstract
    ​ ​Timofeeva, Maria N., Silke Kropp, Wiebke Sauter, Albert Rosenberger, Thomas Illig, Hendrik Dienemann, Heike Bickeboeller, Jenny Chang-Claude, Angela Risch, and H. E. Wichman. "Glutathione-S-transferase T1, M1 and P1 polymorphisms as risk factors for early onset lung cancer​." ​EJC SUPPLEMENTS ​6​, ​no. 9 (2008): https://doi.org/10.1016/S1359-6349(08)71344-2.
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  • 2008 Journal Article
    ​ ​Mueller, Martina, Angela Doering, Helmut Kuechenhoff, Claudia Lamina, Doerthe Malzahn, Heike Bickeboeller, Caren Vollmert et al. "Quantifying the contribution of genetic variants for survival phenotypes​." ​Genetic Epidemiology ​32, no. 6 (2008): ​574​-585​. ​https://doi.org/10.1002/gepi.20333.
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  • 2008 Journal Article
    ​ ​Ludajic, Katarina, Yesilda Balavarca, Heike Bickeboeller, David Pohlreich, Michal Kouba, Marie Dobrovolna, Milena Vrana et al. "Impact of HLA-DPB1 allelic and single amino acid mismatches on HSCT​." ​British Journal of Haematology ​142, no. 3 (2008): ​436​-443​. ​https://doi.org/10.1111/j.1365-2141.2008.07177.x.
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  • 2008 Journal Article | 
    ​ ​Dressel, Ralf, Jan Schindehuette, Tanja Kuhlmann, Leslie Elsner, Peter Novota, Paul Christian Baier, Arne Schillert et al. "The Tumorigenicity of Mouse Embryonic Stem Cells and In Vitro Differentiated Neuronal Cells Is Controlled by the Recipients' Immune Response​." ​PLoS ONE ​3, no. 7 (2008): ​e2622​. ​https://doi.org/10.1371/journal.pone.0002622.
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  • 2008 Journal Article
    ​ ​Novota, Peter, Lisbet Sviland, Severin Zinocker, Pawel Stocki, Yesilda Balavarca, Heike Bickeboeller, Bent Rolstad, X. Wang, Anne. M. Dickson, and Ralf Dressel. "Correlation of Hsp70-1 and Hsp70-2 gene expression with the degree of graft-versus-host reaction in a rat skin explant model​." ​Transplantation Journal ​85, no. 12 (2008): ​1809​-1816​. ​https://doi.org/10.1097/TP.0b013e31817753f7.
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  • 2008 Journal Article
    ​ ​Schneider, Joachim, Thomas Illig, Albert Rosenberger, Heike Bickeboeller, and Hans-Erich Wichmann. "Detection of ATM gene mutations in young lung cancer patients: A population-based control study​." ​Archives of Medical Research ​39, no. 2 (2008): ​226​-231​. ​https://doi.org/10.1016/j.arcmed.2007.08.004.
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  • 2007 Conference Abstract
    ​ ​Neumann, Arne, Doerthe Malzahn, Martina Mueller, and Heike Bickeboeller. "Nonparametric detection of genes and their interaction influencing the longitudinal course of a phenotype​." ​Annals of Human Genetics ​71​ ​(2007): 
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  • 2007 Conference Abstract
    ​ ​Bickeboeller, Heike. "In the face of the complexity - The challenges of genotypes-environment-interaction​." ​Der Nervenarzt ​78​ ​(2007): 
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  • 2007 Conference Abstract
    ​ ​Malzahn, D., A. Neumann, M. Mueller, Heinz-Erich Wichmann, and Heike Bickeboeller. "A non-parametric approach to detect gene-gene and gene-time interaction for longitudinal data in cohort studies​." ​Genetic Epidemiology ​31​, ​no. 5 (2007): ​487​-488. 
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  • 2007 Conference Abstract
    ​ ​Kotti, Salma, Heike Bickeboller, and Francoise Clerget-Darpoux. "Estimation of the genotype relative risk using one or three pseudocontrols in family based analyses​." ​Annals of Human Genetics ​71​ ​(2007): 
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  • 2007 Conference Abstract
    ​ ​Kotti, Salma, E. Clerget-Darpoux, and Heike Bickeboeller. "Genotype relative risk estimation using logistic regression methods in family based data​." ​Genetic Epidemiology ​31​, ​no. 6 (2007): 
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  • 2007 Journal Article | Research Paper | 
    ​ ​Cordell, Heather J., Mariza de Andrade, Marie-Claude Babron, Christopher W. Bartlett, Joseph Beyene, Heike Bickeböller, Robert Culverhouse et al. "Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci​." ​BMC Proceedings ​1, no. Suppl 1 (2007): ​S1​. ​https://doi.org/10.1186/1753-6561-1-S1-S1.
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  • 2007 Journal Article | 
    ​ ​Köhler, Karola, Melanie Sohns, and Heike Bickeböller. "Case-control studies with affected sibships​." ​BMC Proceedings ​1, no. Suppl 1 (2007): ​S29​. ​https://doi.org/10.1186/1753-6561-1-s1-s29.
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  • 2007 Conference Abstract
    ​ ​Roessler, Ute, Albert Rosenberger, Wiebke Sauter, Heike Bickeboeller, Thomas Illig, Heinz-Erich Wichmann, Sabine Hornhardt, and Maria Gomolka. "Association between gene polymorphisms and the DNA repair capacity in young lung cancer patients.​." ​Environmental and Molecular Mutagenesis ​48​, ​no. 7 (2007): 
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  • 2007 Conference Abstract
    ​ ​Stark, W., D. van Rossum, Albert Rosenberger, Heike Bickeboeller, Wolfgang Brueck, and J. Gaertner. "Influence of gene polymorphisms on MS susceptibility and clinical presentation in childhood multiple sclerosis patients​." ​MULTIPLE SCLEROSIS ​13​ ​(2007): 
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  • 2007 Journal Article
    ​ ​Heutelbeck, Astrid R. R., Nico Janicke, Reinhard Hilgers, Birgitta Kutting, Hans G. Drexler, Ernst Hallier, and Heike Bickeboeller. "German cattle allergy study (CAS): public health relevance of cattle-allergic farmers​." ​International Archives of Occupational and Environmental Health ​81, no. 2 (2007): ​201​-208​. ​https://doi.org/10.1007/s00420-007-0207-y.
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  • 2007 Journal Article
    ​ ​Elsner, Leslie, Vijayakumar Muppala, Mathias Gehrmann, Jingky Lozano, Dörthe Malzahn, Heike Bickeböller, Edgar Brunner et al. "The Heat Shock Protein HSP70 Promotes Mouse NK Cell Activity against Tumors That Express Inducible NKG2D Ligands​." ​The Journal of Immunology ​179, no. 8 (2007): ​5523​-5533​. ​https://doi.org/10.4049/jimmunol.179.8.5523.
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  • 2007 Journal Article
    ​ ​Kotti, Salma, Heike Bickeboeller, and F. Clerget-Darpoux. "Strategy for detecting susceptibility genes with weak or no marginal effect​." ​Human Heredity ​63, no. 2 (2007): ​85​-92​. ​https://doi.org/10.1159/000099180.
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  • 2007 Conference Paper
    ​ ​Bickebller, Heike, Katrina A. B. Goddard, Robert P., Jr. Igo, Peter Kraft, Jingky P. Lozano, and Nathan Pankratz. "Issues in association mapping with high-density SNP data and diverse family structures​." ​Genetic Epidemiology ​31​ ​(2007): ​S22​-S33. https://doi.org/10.1002/gepi.20277.
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  • 2007 Journal Article | 
    ​ ​Rosenberger, Albert, Manu Sharma, Bertram Mueller-Myhsok, Thomas Gasser, and Heike Bickeboeller. "Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease​." ​BMC Genetics ​8 (2007): ​44​. ​https://doi.org/10.1186/1471-2156-8-44.
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  • 2006 Conference Abstract
    ​ ​Maouzi, Adil B., R. Wietzke-Braun, Larissa Bettina Maenhardt, Heike Bickeboeller, Giuliano Ramadori, and Sabine Mihm. "Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection​." ​Journal of Clinical Virology ​36​ ​(2006): https://doi.org/10.1016/S1386-6532(06)80174-5.
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  • 2006 Journal Article
    ​ ​Wietzke-Braun, Perdita, Adil B. Maouzi, Larissa Bettina Maenhardt, Heike Bickeboeller, Giuliano Ramadori, and Sabine Mihm. "Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection​." ​European Journal of Gastroenterology & Hepatology ​18, no. 9 (2006): ​991​-997​. ​https://doi.org/10.1097/01.meg.0000224478.89545.76.
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  • 2006 Journal Article
    ​ ​Kohler, K., and Heike Bickeboeller. "Case-control association tests correcting for population stratification​." ​Annals of Human Genetics ​70 (2006): ​98​-115​. ​https://doi.org/10.1111/j.1529-8817.2005.00214.x.
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  • 2006 Journal Article | 
    ​ ​Berger, M., H. H. Stassen, K. Kohler, V. Krane, D. Monks, C. Wanner, K. Hoffmann et al. "Hidden population substructures in an apparently homogeneous population bias association studies​." ​European Journal of Human Genetics ​14, no. 2 (2006): ​236​-244​. ​https://doi.org/10.1038/sj.ejhg.5201546.
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  • 2006 Journal Article
    ​ ​Ghebremedhin, Estifanos, Kelly Del Tredici, Mario Vuksic, Udo Rüb, Dietmar R Thal, Guido J Burbach, Albert Rosenberger et al. "Relationship of Apolipoprotein E and Age at Onset to Parkinson Disease Neuropathology​." ​Journal of Neuropathology and Experimental Neurology ​65, no. 2 (2006): ​116​-123​. ​https://doi.org/10.1097/01.jnen.0000199572.96472.1c.
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  • 2006 Journal Article
    ​ ​Vollmert, Caren, Otto Windl, Wei Xiang, Albert Rosenberger, I. Zerr, H-E Wichmann, Heike Bickeboeller, Thomas Illig, and Hans A. Kretzschmar. "Significant association of a M129V independent polymorphism in the 5 ' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study​." ​Journal of Medical Genetics ​43, no. 10 (2006): ​e53​. ​https://doi.org/10.1136/jmg.2006.040931.
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  • 2006 Journal Article
    ​ ​Riemenschneider, Matthias, Lidija Konta, Patricia Friedrich, Sandra Schwarz, Kevin Taddei, Frauke Neff, Alessandro Padovani et al. "A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease​." ​Human Molecular Genetics ​15, no. 16 (2006): ​2446​-2456​. ​https://doi.org/10.1093/hmg/ddl167.
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  • 2005 Journal Article
    ​ ​Bickeböller, H., P. Margaritte-Jeannin, M.-C. Babron, and F. Clerget-Darpoux. "Systematic search of susceptibility loci with methods using gametic disequilibrium​." ​Genetic Epidemiology ​12, no. 6 (2005): ​577​-582​. ​https://doi.org/10.1002/gepi.1370120609.
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  • 2005 Journal Article
    ​ ​Bickeböller, Heike, and FrançOise Clerget-Darpoux. "Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers​." ​Genetic Epidemiology ​12, no. 6 (2005): ​865​-870​. ​https://doi.org/10.1002/gepi.1370120656.
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  • 2005 Journal Article
    ​ ​Clerget-Darpoux, Françoise, Marie-Claude Babron, and Heike Bickeböller. "Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test​." ​Genetic Epidemiology ​12, no. 6 (2005): ​583​-588​. ​https://doi.org/10.1002/gepi.1370120610.
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  • 2005 Conference Abstract
    ​ ​Kohler, K., and Heike Bickeboeller. "Structured Association tests in case-control studies​." ​Annals of Human Genetics ​69​ ​(2005): 
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  • 2005 Journal Article | Research Paper
    ​ ​Wojnowski, Leszek, Bettina Kulle, Markus Schirmer, Georg Schlüter, Albrecht Schmidt, Albert Rosenberger, Stefan Vonhof et al. "NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity​." ​Circulation ​112, no. 24 (2005): ​3754​-3762​. ​https://doi.org/10.1161/CIRCULATIONAHA.105.576850.
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  • 2005 Journal Article | Letter Note | 
    ​ ​Bailey-Wilson, J. E., L. Almasy, M. de Andrade, Jeremy A. Bailey, Heike Bickeboeller, H. J. Cordell, E. W. Daw et al. "Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans​." ​BMC Genetics ​6 (2005): ​S1​. ​https://doi.org/10.1186/1471-2156-6-S1-S1.
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  • 2005 Journal Article | Research Paper
    ​ ​Kulle, Bettina, M Schirmer, Mohammad Reza Toliat, A. Suk, C. Becker, Mladen Tzvetkov, Jürgen Brockmöller et al. "Application of genomewide SNP arrays for detection of simulated susceptibility loci​." ​Human Mutation ​25, no. 6 (2005): ​557​-565​. ​https://doi.org/10.1002/humu.20174.
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  • 2005 Conference Paper
    ​ ​Bickeboeller, Heike, Julia N. Bailey, G. J. Papanicolaou, Albert Rosenberger, and K. R. Viel. "Dissection of heterogeneous phenotypes for quantitative trait mapping​." ​Genetic Epidemiology ​29​ ​(2005): ​S41​-S47. https://doi.org/10.1002/gepi.20109.
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  • 2005 Journal Article
    ​ ​Berger, M., Manuel Mattheisen, Bettina Kulle, H. Schmidt, Johannes Oldenburg, Heike Bickeboeller, U. Walter, T. H. Lindner, K. Strauch, and C. M. Schambeck. "High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11​." ​Blood ​105, no. 2 (2005): ​638​-644​. ​https://doi.org/10.1182/blood-2004-05-2018.
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  • 2005 Conference Paper | 
    ​ ​Rosenberger, Albert, N. Janicke, K. Kohler, Katrin Korb, Bettina Kulle, and Heike Bickeboeller. "Surrogate phenotype definition for alcohol use disorders: a genome-wide search for linkage and association​." ​BMC Genetics ​6​ ​(2005): ​S55. https://doi.org/10.1186/1471-2156-6-S1-S55.
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  • 2004 Conference Abstract
    ​ ​Riemenschneider, M., Norman Klopp, S. Schwarz, L. Maljkovic, S. Wagenpfeil, H. Gohlke, Thomas Illig et al. "The chromosome 10 locus and AD: Recent progress of the German national genome network initiative​." ​Neurobiology of Aging ​25​ ​(2004): https://doi.org/10.1016/S0197-4580(04)80184-2.
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  • 2004 Conference Abstract
    ​ ​Wojnowski, Leszek, G. Schlueter, S. Vonhof, Bettina Kulle, Heike Bickeboeller, Markus Loeffler, Michael Pfreundschuh, Juergen Brockmoeller, Gerd Hasenfuß, and Lorenz H. Truemper. "Nad(p)h oxidase and MRP genetic polymorphisms associate with doxorubicin-induced cardiotoxicity​." ​Journal of Clinical Oncology ​22​, ​no. 14 (2004): 
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  • 2004 Conference Abstract
    ​ ​Wojnowski, Leszek, G. Schluter, S. Vonhof, Bettina Kulle, Heike Bickeboeller, Mohammad Reza Toliat, E. K. Suk et al. "Association of NAD(P)H oxidase and MRP genetic polymorphisms with doxorubicin-induced cardiotoxicity​." ​Naunyn-Schmiedeberg s Archives of Pharmacology ​369​ ​(2004): 
    Details  WoS 
  • 2004 Conference Abstract
    ​ ​Schirmer, Markus Anton, Leszek Wojnowski, G. Schluter, S. Vonhof, Bettina Kulle, Heike Bickeboeller, Mohammad Reza Toliat et al. "NAD(P)H oxidase and MRP genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity​." ​Circulation ​110​, ​no. 17 (2004): ​807​-808. 
    Details  WoS 
  • 2003 Conference Paper
    ​ ​Bickeboeller, Heike, J. H. Barrett, K. B. Jacobs, and Albert Rosenberger. "Modeling and dissection of longitudinal blood pressure and hypertension phenotypes in genetic epidemiological studies​." ​Genetic Epidemiology ​25​ ​(2003): ​S72​-S77. https://doi.org/10.1002/gepi.10287.
    Details  DOI  PMID  PMC  WoS 
  • 2003 Conference Paper | 
    ​ ​Kulle, Bettina, K. Kohler, Albert Rosenberger, S. Loesgen, and Heike Bickeboeller. "Nonparametric longitudinal allele-sharing model​." ​BMC Genetics ​4​ ​(2003): ​S85. https://doi.org/10.1186/1471-2156-4-S1-S85.
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article
    ​ ​Holmer, S. R., Heike Bickeboeller, C. Hengstenberg, F. Rohlmann, S. Engel, H. Lowel, B. Mayer et al. "Angiotensin converting enzyme gene polymorphism and myocardial infarction a large association and linkage study​." ​The International Journal of Biochemistry & Cell Biology ​35, no. 6 (2003): ​PII S1357-2725(02)00261-3​. ​https://doi.org/10.1016/S1357-2725(02)00261-3.
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  • 2001 Journal Article
    ​ ​Immervoll, Thomas, Sabine Loesgen, Gabriele Dütsch, Henning Gohlke, Nicole Herbon, Sabine Klugbauer, Astrid Dempfle et al. "Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes​." ​Human Mutation ​18, no. 4 (2001): ​327​-336​. ​https://doi.org/10.1002/humu.1194.
    Details  DOI 
  • 2000 Journal Article | Research Paper
    ​ ​Bickeböller, Heike. "Investigation of Linkage and Association: Issues on Study Design​." ​International Statistical Review ​68, no. 1 (2000): ​75​. ​https://doi.org/10.2307/1403558.
    Details  DOI 
  • 2000 Journal Article
    ​ ​ULBRECHT, MATTHIAS, MARKUS THOMAS HERGETH, MATTHIAS WJST, JOACHIM HEINRICH, Heike Bickeböller, HEINZ-ERICH WICHMANN, and ELISABETH HELENE WEISS. "Association of β 2 -Adrenoreceptor Variants with Bronchial Hyperresponsiveness​." ​American Journal of Respiratory and Critical Care Medicine ​161, no. 2 (2000): ​469​-474​. ​https://doi.org/10.1164/ajrccm.161.2.9902072.
    Details  DOI 
  • 1999 Journal Article | 
    ​ ​Scholz, Michael, Hans-Georg Kraft, Arnulf Lingenhel, Rhena Delport, Est´ H Vorster, Heike Bickeböller, and Gerd Utermann. "Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians​." ​European Journal of Human Genetics ​7, no. 2 (1999): ​169​-178​. ​https://doi.org/10.1038/sj.ejhg.5200290.
    Details  DOI 
  • 1997 Journal Article
    ​ ​Bickeböller, Heike, Maria Kistler, and Michael Scholz. "Investigation of the candidate genes ACTHR and Golf for bipolar illness by the transmission/disequilibrium test​." ​Genetic Epidemiology ​14, no. 6 (1997): ​575​-580​. ​https://doi.org/10.1002/(SICI)1098-2272(1997)14:6<575::AID-GEPI4>3.0.CO;2-Z.
    Details  DOI 
  • 1996 Journal Article
    ​ ​Bickeböller, Heike, and Elizabeth A. Thompson. "Distribution of Genome Shared IBD by Half-Sibs: Approximation by the Poisson Clumping Heuristic​." ​Theoretical Population Biology ​50, no. 1 (1996): ​66​-90​. ​https://doi.org/10.1006/tpbi.1996.0023.
    Details  DOI 

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