Prof Dr. Christian Eggeling

 
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  • 2018 Journal Article | Research Paper | 
    ​ ​Ando, Toshio, et al. "The 2018 correlative microscopy techniques roadmap​." ​Journal of Physics. D, Applied Physics, vol. 51, no. 44, ​2018, , ​doi: 10.1088/1361-6463/aad055. 
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  • 2017 Journal Article | 
    ​ ​Chojnacki, Jakub, et al. "Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state​." ​Nature Communications, vol. 8, no. 1, ​2017, , ​doi: 10.1038/s41467-017-00515-6. 
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  • 2016 Journal Article | Research Paper
    ​ ​Steshenko, Olena, et al. "Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy​." ​Biophysical Journal, vol. 110, no. 11, ​2016, pp. 2441​-2450​, ​doi: 10.1016/j.bpj.2016.04.047. 
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  • 2015 Review
    ​ ​Hell, Stefan, et al. "The 2015 super-resolution microscopy roadmap​." ​Journal of Physics D: Applied Physics, vol. 48, no. 44, ​2015, , ​doi: 10.1088/0022-3727/48/44/443001. 
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  • 2015 Journal Article | Research Paper
    ​ ​Vicidomini, Giuseppe, et al. "STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics​." ​Nano Letters, vol. 15, no. 9, ​2015, pp. 5912​-5918​, ​doi: 10.1021/acs.nanolett.5b02001. 
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  • 2015 Review
    ​ ​Eggeling, Christian, et al. "Lens-based fluorescence nanoscopy​." ​Quarterly Reviews of Biophysics, vol. 48, no. 2, ​2015, pp. 178​-243​, ​doi: 10.1017/S0033583514000146. 
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  • 2015 Journal Article | Research Paper | 
    ​ ​Andrade, Débora Machado, et al. "Cortical actin networks induce spatio-temporal confinement of phospholipids in the plasma membrane - a minimally invasive investigation by STED-FCS​." ​Scientific Reports, vol. 5, ​2015, , ​doi: 10.1038/srep11454. 
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  • 2015 Journal Article | 
    ​ ​Milovanovic, Dragomir, et al. "Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains​." ​Nature Communications, vol. 6, ​2015, , ​doi: 10.1038/ncomms6984. 
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  • 2014 Journal Article
    ​ ​Honigmann, Alf, et al. "A Lipid Bound Actin Meshwork Organizes Liquid Phase Separation in Model Membranes​." ​Biophysical Journal, vol. 106, no. 2, Supplement 1, ​2014, pp. 634a​-634a​, ​doi: 10.1016/j.bpj.2013.11.3506. 
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  • 2014 Journal Article | Research Paper | 
    ​ ​Honigmann, Alf, et al. "Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells​." ​Nature Communications, vol. 5, ​2014, , ​doi: 10.1038/ncomms6412. 
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  • 2014 Journal Article | Research Paper | 
    ​ ​Honigmann, Alf, et al. "A lipid bound actin meshwork organizes liquid phase separation in model membranes​." ​eLife, vol. 3, ​2014, , ​doi: 10.7554/eLife.01671. 
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  • 2014 Journal Article | Research Paper | 
    ​ ​Saka, Sinem K., et al. "Multi-protein assemblies underlie the mesoscale organization of the plasma membrane​." ​Nature Communications, vol. 5, ​2014, , ​doi: 10.1038/ncomms5509. 
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  • 2014 Journal Article | Research Paper
    ​ ​Sahl, Steffen J., et al. "High-Resolution Tracking of Single-Molecule Diffusion in Membranes by Confocalized and Spatially Differentiated Fluorescence Photon Stream Recording​." ​ChemPhysChem, vol. 15, no. 4, ​2014, pp. 771​-783​, ​doi: 10.1002/cphc.201301090. 
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  • 2014 Journal Article | Research Paper
    ​ ​Schönle, Andreas, et al. "Monitoring Triplet State Dynamics With Fluorescence Correlation Spectroscopy: Bias and Correction​." ​Microscopy Research and Technique, vol. 77, no. 7, ​2014, pp. 528​-536​, ​doi: 10.1002/jemt.22368. 
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  • 2013 Journal Article
    ​ ​Eggeling, Christian, et al. "New Insight into Lipid-Protein Membrane Organization and its Functionality with Super-Resolution STED Microscopy​." ​Biophysical Journal, vol. 104, no. 2, ​2013, , ​doi: 10.1016/j.bpj.2012.11.047. 
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  • 2013 Journal Article
    ​ ​Andrade, Debora Machado, et al. "Lipid Hop Diffusion on the Plasma Membrane - a STED-FCS Investigation​." ​Biophysical Journal, vol. 104, no. 2, ​2013, pp. 193a​-194a​, ​doi: 10.1016/j.bpj.2012.11.1091. 
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  • 2013 Journal Article | Research Paper
    ​ ​Honigmann, Alf, et al. "Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment​." ​Nature Structural & Molecular Biology, vol. 20, no. 6, ​2013, pp. 679​-686​, ​doi: 10.1038/nsmb.2570. 
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  • 2013 Journal Article | Research Paper
    ​ ​Chmyrov, Andriy, et al. "Nanoscopy with more than 100,000 'doughnuts'​." ​Nature Methods, vol. 10, no. 8, ​2013, pp. 737​-742​, ​doi: 10.1038/nmeth.2556. 
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  • 2013 Journal Article | Research Paper
    ​ ​Vicidomini, Giuseppe, et al. "STED Nanoscopy with Time-Gated Detection: Theoretical and Experimental Aspects​." ​PLoS ONE, vol. 8, no. 1, ​2013, , ​doi: 10.1371/journal.pone.0054421. 
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  • 2013 Journal Article | Research Paper
    ​ ​Honigmann, Alf, et al. "STED microscopy detects and quantifies liquid phase separation in lipid membranes using a new far-red emitting fluorescent phosphoglycerolipid analogue​." ​Faraday Discussions, vol. 161, ​2013, pp. 77​-89​, ​doi: 10.1039/c2fd20107k. 
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  • 2012 Journal Article
    ​ ​Hell, Stefan, et al. "Reversibly switchable rnhanced green fluorescent protein (rsEGFP): A novel photochromic fluorescent protein enables RESOLFT-type microscopy of living cells at low light intensities​." ​Protein science : PS / Supplement, vol. 21, no. 1, ​2012, . ​
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  • 2012 Journal Article
    ​ ​Hell, Stefan, et al. "Dreiklang - the one, two, three in photoswitching​." ​Protein Science / Supplement, vol. 21, no. 1, ​2012, . ​
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  • 2012 Journal Article | Research Paper
    ​ ​Han, Kyu Young, et al. "Dark state photophysics of nitrogen-vacancy centres in diamond​." ​New Journal of Physics, vol. 14, ​2012, , ​doi: 10.1088/1367-2630/14/12/123002. 
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  • 2012 Journal Article | Research Paper
    ​ ​Testa, Ilaria, et al. "Nanoscopy of Living Brain Slices with Low Light Levels​." ​Neuron, vol. 75, no. 6, ​2012, pp. 992​-1000​, ​doi: 10.1016/j.neuron.2012.07.028. 
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  • 2012 Journal Article | Research Paper
    ​ ​Leutenegger, Marcel, et al. "Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS)​." ​Optics Express, vol. 20, no. 5, ​2012, pp. 5243​-5263​, ​doi: 10.1364/OE.20.005243. 
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  • 2012 Journal Article | Research Paper
    ​ ​Vicidomini, Giuseppe, et al. "STED with wavelengths closer to the emission maximum​." ​Optics Express, vol. 20, no. 5, ​2012, pp. 5225​-5236​, ​doi: 10.1364/OE.20.005225. 
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  • 2012 Journal Article | Research Paper | 
    ​ ​Grotjohann, Tim, et al. "rsEGFP2 enables fast RESOLFT nanoscopy of living cells​." ​eLife, vol. 1, ​2012, pp. 1​-14​, ​doi: 10.7554/eLife.00248. 
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  • 2011 Journal Article
    ​ ​Hell, Stefan, et al. "A new class of reversibly switchable fluorescent proteins​." ​European biophysics journal : with biophysics letters, vol. 40, no. 1, ​2011, . ​
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  • 2011 Journal Article
    ​ ​Hell, Stefan, et al. "Imaging membrane heterogeneities and domains by super-resolution STED nanoscopy​." ​European biophysics journal : with biophysics letters / Supplement, vol. 40, no. 1, ​2011, . ​
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  • 2011 Journal Article | Research Paper
    ​ ​Vicidomini, Giuseppe, et al. "Sharper low-power STED nanoscopy by time gating​." ​Nature Methods, vol. 8, no. 7, ​2011, pp. 571​-573​, ​doi: 10.1038/NMETH.1624. 
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  • 2011 Journal Article | Research Paper | 
    ​ ​Grotjohann, Tim, et al. "Diffraction-unlimited all-optical imaging and writing with a photochromic GFP​." ​Nature, vol. 478, ​2011, pp. 204​-208​, ​doi: 10.1038/nature10497. 
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  • 2011 Journal Article | Research Paper
    ​ ​Brakemann, Tanja, et al. "A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching​." ​Nature Biotechnology, vol. 29, no. 10, ​2011, pp. 942​-U132​, ​doi: 10.1038/nbt.1952. 
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  • 2011 Journal Article | Research Paper
    ​ ​Mueller, Veronica, et al. "STED Nanoscopy Reveals Molecular Details of Cholesterol- and Cytoskeleton-Modulated Lipid Interactions in Living Cells​." ​Biophysical Journal, vol. 101, no. 7, ​2011, pp. 1651​-1660​, ​doi: 10.1016/j.bpj.2011.09.006. 
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  • 2010 Journal Article | Research Paper
    ​ ​Kolmakov, Kirill, et al. "A Versatile Route to Red-Emitting Carbopyronine Dyes for Optical Microscopy and Nanoscopy​." ​European Journal of Organic Chemistry, vol. 2010, no. 19, ​2010, pp. 3593​-3610​, ​doi: 10.1002/ejoc.201000343. 
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  • 2010 Journal Article
    ​ ​Honigmann, A., et al. "Characterization of horizontal lipid bilayers as a model system to study lipid phase separation​." ​Biophysical Journal, vol. 98, no. 12, ​2010, pp. 2886​-2894​, ​doi: 10.1016/j.bpj.2010.03.033. 
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  • 2010 Journal Article | Research Paper
    ​ ​Kolmakov, Kirill, et al. "Red-Emitting Rhodamine Dyes for Fluorescence Microscopy and Nanoscopy​." ​Chemistry - A European Journal, vol. 16, no. 1, ​2010, pp. 158​-166​, ​doi: 10.1002/chem.200902309. 
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  • 2010 Journal Article | Research Paper
    ​ ​Bierwagen, Jakob, et al. "Far-Field Autofluorescence Nanoscopy​." ​Nano Letters, vol. 10, no. 10, ​2010, pp. 4249​-4252​, ​doi: 10.1021/nl1027638. 
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  • 2010 Journal Article | Research Paper
    ​ ​Leutenegger, Marcel, Christian Eggeling, and Stefan Hell. "Analytical description of STED microscopy performance​." ​Optics Express, vol. 18, no. 25, ​2010, pp. 26417​-26429​, ​doi: 10.1364/OE.18.026417. 
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  • 2010 Journal Article | Research Paper
    ​ ​Mitronova, Gyuzel Yu, et al. "New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy​." ​Chemistry - A European Journal, vol. 16, no. 15, ​2010, pp. 4477​-4488​, ​doi: 10.1002/chem.200903272. 
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  • 2010 Journal Article | Research Paper
    ​ ​Sahl, Steffen J., et al. "Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids​." ​Proceedings of the National Academy of Sciences, vol. 107, no. 15, ​2010, pp. 6829​-6834​, ​doi: 10.1073/pnas.0912894107. 
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  • 2010 Journal Article | Research Paper
    ​ ​Han, Kyu Young, et al. "Metastable Dark States Enable Ground State Depletion Microscopy of Nitrogen Vacancy Centers in Diamond with Diffraction-Unlimited Resolution​." ​Nano Letters, vol. 10, no. 8, ​2010, pp. 3199​-3203​, ​doi: 10.1021/nl102156m. 
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  • 2010 Journal Article | Research Paper
    ​ ​Testa, Ilaria, et al. "Multicolor Fluorescence Nanoscopy in Fixed and Living Cells by Exciting Conventional Fluorophores with a Single Wavelength​." ​Biophysical Journal, vol. 99, no. 8, ​2010, pp. 2686​-2694​, ​doi: 10.1016/j.bpj.2010.08.012. 
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  • 2010 Journal Article | Research Paper
    ​ ​Brakemann, Tanja, et al. "Molecular Basis of the Light-driven Switching of the Photochromic Fluorescent Protein Padron​." ​Journal of biological chemistry, vol. 285, no. 19, ​2010, pp. 14603​-14609​, ​doi: 10.1074/jbc.M109.086314. 
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  • 2009 Journal Article | Research Paper
    ​ ​Rittweger, Eva, et al. "STED microscopy reveals crystal colour centres with nanometric resolution​." ​Nature Photonics, vol. 3, no. 3, ​2009, pp. 144​-147​, ​doi: 10.1038/NPHOTON.2009.2. 
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  • 2009 Review
    ​ ​Polyakova, Svetlana, et al. "New GM1 Ganglioside Derivatives for Selective Single and Double Labelling of the Natural Glycosphingolipid Skeleton​." ​European Journal of Organic Chemistry, vol. 2009, no. 30, ​2009, pp. 5162​-5177​, ​doi: 10.1002/ejoc.200900645. 
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  • 2009 Journal Article | Research Paper
    ​ ​Ringemann, Christian, et al. "Exploring single-molecule dynamics with fluorescence nanoscopy​." ​New Journal of Physics, vol. 11, ​2009, , ​doi: 10.1088/1367-2630/11/10/103054. 
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  • 2009 Journal Article | Research Paper
    ​ ​Han, Kyu Young, et al. "Three-Dimensional Stimulated Emission Depletion Microscopy of Nitrogen-Vacancy Centers in Diamond Using Continuous-Wave Light​." ​Nano Letters, vol. 9, no. 9, ​2009, pp. 3323​-3329​, ​doi: 10.1021/nl901597v. 
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  • 2009 Journal Article | Research Paper
    ​ ​Eggeling, Christian, et al. "Direct observation of the nanoscale dynamics of membrane lipids in a living cell​." ​Nature, vol. 457, no. 7233, ​2009, pp. 1159​-1162​, ​doi: 10.1038/nature07596. 
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  • 2009 Journal Article | Research Paper
    ​ ​Donnert, Gerald, Christian Eggeling, and Stefan Hell. "Triplet-relaxation microscopy with bunched pulsed excitation​." ​Photochemical & Photobiological Sciences, vol. 8, no. 4, ​2009, pp. 481​-485​, ​doi: 10.1039/b903357m. 
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  • 2008 Journal Article | Research Paper | 
    ​ ​Andresen, Martin, et al. "Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy​." ​Nature Biotechnology, vol. 26, no. 9, ​2008, pp. 1035​-1040​, ​doi: 10.1038/nbt.1493. 
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  • 2008 Journal Article | Research Paper
    ​ ​Fölling, Jonas, et al. "Fluorescence nanoscopy with optical sectioning by two-photon induced molecular switching using continuous-wave lasers​." ​ChemPhysChem, vol. 9, no. 2, ​2008, pp. 321​-326​, ​doi: 10.1002/cphc.200700655. 
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  • 2008 Journal Article | Research Paper
    ​ ​Ringemann, Christian, et al. "Enhancing fluorescence brightness: Effect of reverse intersystem crossing studied by fluorescence fluctuation spectroscopy​." ​ChemPhysChem, vol. 9, no. 4, ​2008, pp. 612​-624​, ​doi: 10.1002/cphc.200700596. 
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  • 2008 Journal Article | Research Paper
    ​ ​Testa, Ilaria, et al. "Nanoscale separation of molecular species based on their rotational mobility​." ​Optics Express, vol. 16, no. 25, ​2008, pp. 21093​-21104​, ​doi: 10.1364/OE.16.021093. 
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  • 2008 Journal Article | Research Paper
    ​ ​Fölling, Jonas, et al. "Fluorescence nanoscopy by ground-state depletion and single-molecule return​." ​Nature Methods, vol. 5, no. 11, ​2008, pp. 943​-945​, ​doi: 10.1038/nmeth.1257. 
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  • 2008 Journal Article | Research Paper
    ​ ​Stiel, Andre C., et al. "Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy​." ​Biophysical Journal, vol. 95, no. 6, ​2008, pp. 2989​-2997​, ​doi: 10.1529/biophysj.108.130146. 
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  • 2008 Journal Article | Research Paper
    ​ ​Bossi, Mariano L., et al. "Multicolor far-field fluorescence nanoscopy through isolated detection of distinct molecular species​." ​Nano Letters, vol. 8, no. 8, ​2008, pp. 2463​-2468​, ​doi: 10.1021/nl801471d. 
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  • 2007 Journal Article | Research Paper
    ​ ​Bock, H., et al. "Two-color far-field fluorescence nanoscopy based on photoswitchable emitters​." ​Applied Physics B Lasers and Optics, vol. 88, no. 2, ​2007, pp. 161​-165​, ​doi: 10.1007/s00340-007-2729-0. 
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  • 2007 Journal Article | Research Paper
    ​ ​Geisler, Claudia, et al. "Resolution of λ /10 in fluorescence microscopy using fast single molecule photo-switching​." ​Applied Physics A: Materials Science & Processing, vol. 88, no. 2, ​2007, pp. 223​-226​, ​doi: 10.1007/s00339-007-4144-0. 
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  • 2007 Journal Article | Research Paper
    ​ ​Andresen, Martin, et al. "Structural basis for reversible photoswitching in Dronpa​." ​Proceedings of the National Academy of Sciences, vol. 104, no. 32, ​2007, pp. 13005​-13009​, ​doi: 10.1073/pnas.0700629104. 
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  • 2007 Journal Article | Research Paper
    ​ ​Schwentker, Miriam A., et al. "Wide-field subdiffraction RESOLFT microscopy using fluorescent protein photoswitching​." ​Microscopy research and technique, vol. 70, no. 3, ​2007, pp. 269​-280​, ​doi: 10.1002/jemt.20443. 
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  • 2007 Journal Article | Research Paper
    ​ ​Bretschneider, Stefan, Christian Eggeling, and Stefan Hell. "Breaking the diffraction barrier in fluorescence microscopy by optical shelving​." ​Physical Review Letters, vol. 98, no. 21, ​2007, , ​doi: 10.1103/PhysRevLett.98.218103. 
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  • 2007 Journal Article | Research Paper
    ​ ​Fölling, Jonas, et al. "Photochromic rhodamines provide nanoscopy with optical sectioning​." ​Angewandte Chemie International Edition, vol. 46, no. 33, ​2007, pp. 6266​-6270​, ​doi: 10.1002/anie.200702167. 
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  • 2007 Journal Article | Research Paper
    ​ ​Sieber, Jochen J., et al. "Anatomy and dynamics of a supramolecular membrane protein cluster​." ​Science, vol. 317, no. 5841, ​2007, pp. 1072​-1076​, ​doi: 10.1126/science.1141727. 
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  • 2007 Journal Article | Research Paper
    ​ ​Neubauer, Heike, et al. "Orientational and dynamical heterogeneity of rhodamine 6G terminally attached to a DNA helix revealed by NMR and single-molecule fluorescence spectroscopy​." ​Journal of the American Chemical Society, vol. 129, no. 42, ​2007, pp. 12746​-12755​, ​doi: 10.1021/ja0722574. 
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  • 2007 Journal Article | Research Paper
    ​ ​Donnert, Gerald, et al. "Two-color far-field fluorescence nanoscopy​." ​Biophysical Journal, vol. 92, no. 8, ​2007, pp. L67​-L69​, ​doi: 10.1529/biophysj.107.104497. 
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  • 2007 Journal Article | Research Paper
    ​ ​Stiel, Andre C., et al. "1.8 Å bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants​." ​Biochemical Journal, vol. 402, ​2007, pp. 35​-42​, ​doi: 10.1042/BJ20061401. 
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  • 2007 Journal Article | Research Paper
    ​ ​Donnert, Gerald, Christian Eggeling, and Stefan Hell. "Major signal increase in fluorescence microscopy through dark-state relaxation​." ​Nature Methods, vol. 4, no. 1, ​2007, pp. 81​-86​, ​doi: 10.1038/NMETH986. 
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  • 2007 Journal Article | Research Paper
    ​ ​Egner, Alexander, et al. "Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters​." ​Biophysical Journal, vol. 93, no. 9, ​2007, pp. 3285​-3290​, ​doi: 10.1529/biophysj.107.112201. 
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  • 2007 Journal Article | Research Paper
    ​ ​Eggeling, C., et al. "Reversible photoswitching enables single-molecule fluorescence fluctuation Spectroscopy at high molecular concentration​." ​Microscopy research and technique, vol. 70, no. 12, ​2007, pp. 1003​-1009​, ​doi: 10.1002/jemt.20505. 
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  • 2006 Journal Article
    ​ ​Blom, H., L. Kastrup, and C. Eggeling. "Fluorescence spectroscopy in reduced detection volumes​." ​Current Pharmaceutical Biotechnology, vol. 7, no. 1, ​2006, pp. 51​-56​. ​
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  • 2006 Journal Article
    ​ ​Leutenegger, M., et al. "Dual-color total internal reflection fluorescence cross-correlation spectroscopy​." ​Journal of Biomedical Optics, vol. 11, no. 4, ​2006, , ​doi: 10.1117/1.2221714. 
    Details  DOI 
  • 2006 Journal Article | Research Paper
    ​ ​Donnert, Gerald, et al. "Macromolecular-scale resolution in biological fluorescence microscopy​." ​Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 31, ​2006, pp. 11440​-11445​, ​doi: 10.1073/pnas.0604965103. 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article
    ​ ​Andresen, Martin, et al. "Insight into the structure and mechanism of the reversible photoswitch of a fl uorescent protein: ​A multi-departmental research approach​." ​MPIbpc News, vol. 11, no. 12, ​2005, pp. 1​-4​. ​
    Details 
  • 2005 Journal Article
    ​ ​Andresen, Martin, et al. "Insight into the structure and mechanism of the reversible photoswitch of a fluorescent protein: A multi-departmental research approach​." ​MPIbpc news, vol. 11, no. 12, ​2005, . ​
    Details 
  • 2005 Journal Article | Research Paper
    ​ ​Kastrup, Lars, et al. "Fluorescence fluctuation spectroscopy in subdiffraction focal volumes​." ​Physical Review Letters, vol. 94, no. 17, ​2005, , ​doi: 10.1103/PhysRevLett.94.178104. 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Andresen, Martin, et al. "Structure and mechanism of the reversible photoswitch of a fluorescent protein​." ​Proceedings of the National Academy of Sciences, vol. 102, no. 37, ​2005, pp. 13070​-13074​, ​doi: 10.1073/pnas.0502772102. 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Hofmann, Michael, et al. "Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins​." ​Proceedings of the National Academy of Sciences, vol. 102, no. 49, ​2005, pp. 17565​-17569​, ​doi: 10.1073/pnas.0506010102. 
    Details  DOI  PMID  PMC  WoS 

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