Prof. Dr. Kaomei Guan-Schmidt

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  • 2020 | Journal Article
    ​ ​Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation​
    Li, W.; Stauske, M.; Luo, X.; Wagner, S. ; Vollrath, M.; Mehnert, C. S. & Schubert, M. et al.​ (2020) 
    Frontiers in Cell and Developmental Biology, 8.​ DOI: https://doi.org/10.3389/fcell.2020.592893 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Control of p21Cip by BRAP is Critical for Cardiomyocyte Cell Cycle Progression and Survival​
    Volland, C.; Schott, P. ; Didié, M. ; Männer, J. ; Unsöld, B.; Toischer, K.   & Schmidt, C. et al.​ (2019) 
    Cardiovascular Research,.​ DOI: https://doi.org/10.1093/cvr/cvz177 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities​
    Ben Jehuda, R.; Eisen, B.; Shemer, Y.; Mekies, L. N.; Szantai, A.; Reiter, I. & Cui, H. et al.​ (2018) 
    Heart Rhythm, 15(2) pp. 267​-276​.​ DOI: https://doi.org/10.1016/j.hrthm.2017.09.024 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper
    ​ ​Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression​
    Mohamed, B. A. ; Hartmann, N. ; Tirilomis, P.; Sekeres, K.; Li, W.; Neef, S. & Richter, C.  et al.​ (2018) 
    Science Translational Medicine, 10(458) art. eaan0724​.​ DOI: https://doi.org/10.1126/scitranslmed.aan0724 
    ​Details  DOI  PMID  PMC 
  • 2017 | Conference Abstract
    ​ ​P1334 - The relevant role of SR Ca leak in the development of heart failure​
    Mohamed, B. A.; Kattner, L.; Guan, K. ; Lehnart, S. E. ; Luther, S. ; Sossalla, S.   & Hasenfuß, G.  et al.​ (2017)
    European Journal of Heart Failure, 19(Suppl. 1) ​Heart Failure 2017 and the 4th World Congress on Acute Heart Failure​, Paris.
    ​Details 
  • 2017 | Conference Abstract
    ​ ​The relevant role of SR Ca leak in the development of heart failure​
    Mohamed, B. A.; Kattner, L.; Guan, K. ; Lehnart, S. E. ; Luther, S.; Sossalla, S. T.   & Hasenfuß, G.  et al.​ (2017)
    European Journal of Heart Failure, 19 
    Hoboken​: Wiley.
    ​Details  WoS 
  • 2017 | Journal Article | Overview
    ​ ​PDE2 at the crossway between cAMP and cGMP signalling in the heart​
    Weber, S.; Zeller, M.; Guan, K. ; Wunder, F.; Wagner, M. & El-Armouche, A. ​ (2017) 
    Cellular Signalling, 38 pp. 76​-84​.​ DOI: https://doi.org/10.1016/j.cellsig.2017.06.020 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper
    ​ ​Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention​
    Chowdhury, S. K.; Liu, W.; Zi, M.; Li, Y.; Wang, S.; Tsui, H. & Prehar, S. et al.​ (2017) 
    Circulation, 135(7) pp. 683​-699​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.116.022941 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective method​
    Liu, X.; Qi, J.; Xu, X.; Zeisberg, M. ; Guan-Schmidt, K.   & Zeisberg, E. M. ​ (2016) 
    Differentiation, 92(4) pp. 225​-236​.​ DOI: https://doi.org/10.1016/j.diff.2016.05.004 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Conference Abstract
    ​ ​Generation of iPSC-based cardiomyocytes for investigating mechanisms of dilated cardiomyopathy​
    Streckfuss-Boemeke, K.; Tiburcy, M. ; Fomin, V. M.; Fischer, C.; Perrot, A.; Oezcelik, C. & Sossalla, S. T.  et al.​ (2015)
    Acta Physiologica, 213 pp. 23​-24. 
    Hoboken​: Wiley-blackwell.
    ​Details  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Sensing Cardiac Electrical Activity With a Cardiac Myocyte-Targeted Optogenetic Voltage Indicator​
    Chang Liao, M.-L.; Boer, T. P. de; Mutoh, H.; Raad, N.; Richter, C. ; Wagner, E.   & Downie, B. R. et al.​ (2015) 
    Circulation Research, 117(5) pp. 401​-412​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.117.306143 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Efficient Generation of Hepatic Cells from Multipotent Adult Mouse Germ-Line Stem Cells Using an OP9 Co-Culture System​
    Streckfuss-Bömeke, K. ; Jende, J.; Cheng, I.-F. ; Hasenfuß, G.   & Guan, K. ​ (2014) 
    Cellular Reprogramming, 16(1) pp. 65​-76​.​ DOI: https://doi.org/10.1089/cell.2013.0057 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article | Research Paper
    ​ ​Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts​
    Streckfuss-Boemeke, K. ; Wolf, F.; Azizian, A. ; Stauske, M.; Tiburcy, M. ; Wagner, S.   & Huebscher, D.  et al.​ (2013) 
    European heart journal, 34(33) pp. 2618​-2629​.​ DOI: https://doi.org/10.1093/eurheartj/ehs203 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Letter Note
    ​ ​Cardiac resident progenitor cells: evidence and functional significance​
    Guan, K.   & Hasenfuß, G. ​ (2013) 
    European heart journal, 34(36) pp. 2784​-2787​.​ DOI: https://doi.org/10.1093/eurheartj/ehs208 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Conference Abstract
    ​ ​Comparative studies of human induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes and skin fibroblasts​
    Guan, K. ; Streckfuss-Bömeke, K. ; Wolf, F.; Azizian, A.; Stauske, M.; Tiburcy, M.   & Wagner, S. et al.​ (2012)
    European Heart Journal, 33 pp. 21​-22. , Munchen, GERMANY.
    Oxford​: Oxford Univ Press.
    ​Details  WoS 
  • 2012 | Journal Article | Research Paper
    ​ ​Age-dependent changes in contractile function and passive elastic properties of myocardium from mice lacking muscle LIM protein (MLP)​
    Unsoeld, B. W.; Schotola, H.; Jacobshagen, C. ; Seidler, T. ; Sossalla, S. ; Emmons, J. & Klede, S. et al.​ (2012) 
    European Journal of Heart Failure, 14(4) pp. 430​-437​.​ DOI: https://doi.org/10.1093/eurjhf/hfs020 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Conference Abstract
    ​ ​Generation of cardiovascular progenitors from multipotent adult mouse germline stem cells​
    Kaiser, D.; Cheng, I.-F.; Unsoeld, B. W.; Toischer, K. ; Schaefer, K. ; Hasenfuß, G.   & Guan, K. ​ (2009)
    Human Gene Therapy, 20(11) ​Combined Meeting of the 17th European-Society-of-Gene-and-Cell-Therapy/16th German-Society-for-Gene-Therapy/4th German-Society-for-Stem-Cell-Research​, Hannover, GERMANY.
    New rochelle​: Mary Ann Liebert Inc.
    ​Details  WoS 
  • 2009 | Journal Article | Research Paper
    ​ ​Generation of functional neurons and glia from multipotent adult mouse germ-line stem cells​
    Streckfuss-Boemeke, K. ; Vlasov, A.; Huelsmann, S. ; Yin, D.; Nayernia, K.; Engel, W. & Hasenfuß, G.  et al.​ (2009) 
    Stem Cell Research, 2(2) pp. 139​-154​.​ DOI: https://doi.org/10.1016/j.scr.2008.09.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | Research Paper
    ​ ​Isolation and cultivation of stem cells from adult mouse testes​
    Guan, K. ; Wolf, F.; Becker, A. ; Engel, W.; Nayernia, K. & Hasenfuß, G. ​ (2009) 
    Nature Protocols, 4(2) pp. 143​-154​.​ DOI: https://doi.org/10.1038/nprot.2008.242 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Conference Paper | Research Paper
    ​ ​Potency of germ cells and its relevance for regenerative medicine​
    Mardanpour, P.; Guan, K. ; Nolte, J. ; Lee, J. H.; Hasenfuß, G. ; Engel, W. & Nayernia, K.​ (2008)
    ​Journal of Anatomy (1) pp. 26​-29. (Vol. 213). ​International Conference on Advances in Stem Cell Biology​, Durham Univ, Durham, ENGLAND.
    Malden​: Wiley-blackwell. DOI: https://doi.org/10.1111/j.1469-7580.2008.00930.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article | Research Paper
    ​ ​Multipotent adult germline stem cells and embryonic stem cells have similar microRNA profiles​
    Zovoilis, A.; Nolte, J. ; Drusenheimer, N.; Zechner, U.; Hada, H.; Guan, K.   & Hasenfuß, G.  et al.​ (2008) 
    Molecular Human Reproduction, 14(9) pp. 521​-529​.​ DOI: https://doi.org/10.1093/molehr/gan044 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Conference Abstract
    ​ ​Disturbed MAPK signaling and heart failure in Impedes Mitogenic Signaling (IMP) transgenic mice​
    Seidler, T.; Schott, P.; Grebe, C.; Unsoeld, B. W.; Schmidt, A.; Koegler, H. & Guan-Schmidt, K.  et al.​ (2007)
    European Heart Journal, 28 
    Oxford​: Oxford Univ Press.
    ​Details  WoS 
  • 2007 | Journal Article | Research Paper
    ​ ​Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells​
    Guan, K. ; Wagner, S. ; Unsoeld, B. W.; Maier, L. S. ; Kaiser, D.; Hemmerlein, B.   & Nayernia, K. et al.​ (2007) 
    Circulation Research, 100(11) pp. 1615​-1625​.​ DOI: https://doi.org/10.1161/01.RES.0000269182.22798.d9 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Review
    ​ ​Do stem cells in the heart truly differentiate into cardiomyocytes?​
    Guan, K.  & Hasenfuß, G. ​ (2007)
    Journal of Molecular and Cellular Cardiology, 43​(4) pp. 377​-387​.​
    Academic Press Ltd- Elsevier Science Ltd. DOI: https://doi.org/10.1016/j.yjmcc.2007.07.056 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | Research Paper
    ​ ​Pluripotency of spermatogonial stem cells from adult mouse testis​
    Guan, K. ; Nayernia, K.; Maier, L. S. ; Wagner, S. ; Dressel, R. ; Lee, J. H. & Nolte, J.  et al.​ (2006) 
    Nature, 440(7088) pp. 1199​-1203​.​ DOI: https://doi.org/10.1038/nature04697 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Conference Abstract
    ​ ​Adult mouse spermatogonial stem cells differentiate into cardiovascular lineages and generate functional cardiomyocytes​
    Guan, K. ; Nayernia, K.; Maier, L. S. ; Wagner, S.; Wolf, F.; Li, M. Y. & Engel, W. et al.​ (2005)
    Circulation Research, 97(11) ​Scientific Meeting of the American-Heart-Association​, Dallas, TX.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2004 | Journal Article | Research Paper
    ​ ​Cellular repopulation of myocardial infarction in patients with sex-mismatched heart transplantation​
    Höcht-Zeisberg, E. ; Kahnert, H.; Guan, K. ; Wulf, G. ; Hemmerlein, B. ; Schlott, T. & Tenderich, G. et al.​ (2004) 
    European heart journal, 25(9) pp. 749​-758​.​ DOI: https://doi.org/10.1016/j.ehj.2004.01.017 
    ​Details  DOI  PMID  PMC  WoS 

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