Dr. med. Stefan Wagner

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  • 2022 | Journal Article
    ​ ​Na v 1.8 Dysregulates Na and Ca Leading to Arrhythmias in Patients with Sleep-disordered Breathing​
    Lebek, S.; Hegner, P.; Hultsch, R.; Rohde, J.; Rupprecht, L.; Schmid, C. & Sossalla, S. T.  et al.​ (2022) 
    American Journal of Respiratory and Critical Care Medicine, art. rccm.202205-0981LE​.​ DOI: https://doi.org/10.1164/rccm.202205-0981LE 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​CaMKIIδC Drives Early Adaptive Ca 2+ Change and Late Eccentric Cardiac Hypertrophy​
    Ljubojevic-Holzer, S.; Herren, A. W.; Djalinac, N.; Voglhuber, J.; Morotti, S.; Holzer, M. & Wood, B. M. et al.​ (2020) 
    Circulation Research, 127(9) pp. 1159​-1178​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.120.316947 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias​
    Pabel, S. ; Mustroph, J.; Stehle, T.; Lebek, S.; Dybkova, N.; Keyser, A. & Rupprecht, L. et al.​ (2020) 
    Europace, 22(7) pp. 1111​-1118​.​ DOI: https://doi.org/10.1093/europace/euaa079 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Contribution of the neuronal sodium channel NaV1.8 to sodium- and calcium-dependent cellular proarrhythmia​
    Bengel, P. ; Ahmad, S. ; Tirilomis, P.; Trum, M.; Dybkova, N.; Wagner, S.   & Maier, L. S.  et al.​ (2020) 
    Journal of Molecular and Cellular Cardiology, 144 pp. 35​-46​.​ DOI: https://doi.org/10.1016/j.yjmcc.2020.05.002 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes​
    Mustroph, J.; Wagemann, O.; Lücht, C. M.; Trum, M.; Hammer, K. P.; Sag, C. M. & Lebek, S. et al.​ (2018) 
    ESC Heart Failure, 5(4) pp. 642​-648​.​ DOI: https://doi.org/10.1002/ehf2.12336 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper
    ​ ​Empagliflozin directly improves diastolic function in human heart failure​
    Pabel, S. ; Wagner, S. ; Bollenberg, H.; Bengel, P. ; Kovács, Á.; Schach, C. & Tirilomis, P. et al.​ (2018) 
    European Journal of Heart Failure, 20(12) pp. 1690​-1700​.​ DOI: https://doi.org/10.1002/ejhf.1328 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart​
    Dybkova, N.; Ahmad, S. ; Pabel, S. ; Tirilomis, P.; Hartmann, N. ; Fischer, T. H   & Bengel, P.  et al.​ (2018) 
    Cardiovascular Research, 114(13) pp. 1728​-1737​.​ DOI: https://doi.org/10.1093/cvr/cvy152 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper | 
    ​ ​Enhanced cardiac TBC1D10C expression lowers heart rate and enhances exercise capacity and survival​
    Volland, C.; Bremer, S. ; Hellenkamp, K. ; Hartmann, N. H. ; Dybkova, N.; Khadjeh, S.   & Kutschenko, A. et al.​ (2016) 
    Scientific Reports, 6 art. 33853​.​ DOI: https://doi.org/10.1038/srep33853 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner​
    Sag, C. M.; Mallwitz, A.; Wagner, S. ; Hartmann, N. ; Schotola, H.; Fischer, T. H.   & Ungeheuer, N. et al.​ (2014) 
    Journal of Molecular and Cellular Cardiology, 76 pp. 94​-105​.​ DOI: https://doi.org/10.1016/j.yjmcc.2014.08.016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease​
    Toischer, K. ; Hartmann, N. ; Wagner, S. ; Fischer, T. H. ; Herting, J. ; Danner, B. C.   & Sag, C. M. et al.​ (2013) 
    Journal of Molecular and Cellular Cardiology, 61 pp. 111​-122​.​ DOI: https://doi.org/10.1016/j.yjmcc.2013.03.021 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper | 
    ​ ​Diastolic dysfunction and arrhythmias caused by overexpression of CaMKII delta(C) can be reversed by inhibition of late Na+ current​
    Sossalla, S. ; Maurer, U.; Schotola, H.; Hartmann, N. H. ; Didie, M. ; Zimmermann, W.-H.   & Jacobshagen, C.  et al.​ (2011) 
    Basic Research in Cardiology, 106(2) pp. 263​-272​.​ DOI: https://doi.org/10.1007/s00395-010-0136-x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | Research Paper | 
    ​ ​Altered Na+ Currents in Atrial Fibrillation Effects of Ranolazine on Arrhythmias and Contractility in Human Atrial Myocardium​
    Sossalla, S. ; Kallmeyer, B.; Wagner, S. ; Mazur, M.; Maurer, U.; Toischer, K.   & Schmitto, J. D. et al.​ (2010) 
    Journal of the American College of Cardiology, 55(21) pp. 2330​-2342​.​ DOI: https://doi.org/10.1016/j.jacc.2009.12.055 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article | Research Paper
    ​ ​Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts - Role of late sodium current and intracellular ion accumulation​
    Sossalla, S. ; Wagner, S. ; Rasenack, E. C. L.; Ruff, H.; Weber, S. L.; Schoendube, F. A.   & Tirilomis, T.  et al.​ (2008) 
    Journal of Molecular and Cellular Cardiology, 45(1) pp. 32​-43​.​ DOI: https://doi.org/10.1016/j.yjmcc.2008.03.006 
    ​Details  DOI  PMID  PMC  WoS 

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