Prof. Dr. Mathias Bähr

 
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  • 2020 Journal Article | Research Paper | 
    ​ ​CARASIL with coronary artery disease and distinct cerebral microhemorrhage: A case report and literature review​
    Müller, S. J.; Khadhraoui, E.; Allam, I.; Argyriou, L.; Hehr, U.; Liman, J.   & Hasenfuß, G.  et al.​ (2020) 
    Clinical and Translational Neuroscience4(1) pp. 1​-5​.​ DOI: https://doi.org/10.1177/2514183X20914182 
    Details  DOI 
  • 2016 Journal Article | Research Paper | 
    ​ ​Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration​
    Zhang, J.-N. ; Michel, U. ; Lenz, C. ; Friedel, C. C.; Köster, S. ; D'Hedouville, Z. & Tönges, L.  et al.​ (2016) 
    Scientific Reports6 art. 37050​.​ DOI: https://doi.org/10.1038/srep37050 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper | 
    ​ ​CatWalk gait analysis in a rat model of multiple sclerosis​
    Herold, S.; Kumar, P.; Jung, K. ; Graf, I.; Menkhoff, H.; Schulz, X.   & Bähr, M.  et al.​ (2016) 
    BMC Neuroscience17 art. 78​.​ DOI: https://doi.org/10.1186/s12868-016-0317-0 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper | 
    ​ ​Transcranial Alternating Current Stimulation Affects the BOLD Signal in a Frequency and Task-dependent Manner​
    Cabral-Calderin, Y. ; Weinrich, C. A. ; Schmidt-Samoa, C. ; Poland, E.; Dechent, P. ; Bähr, M.   & Wilke, M. ​ (2016) 
    Human Brain Mapping37(1) pp. 94​-121​.​ DOI: https://doi.org/10.1002/hbm.23016 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper | 
    ​ ​Brain Metabolite Changes in Patients with Relapsing-Remitting and Secondary Progressive Multiple Sclerosis: A Two-Year Follow-Up Study​
    Obert, D.; Helms, G.; Sättler, M. B. ; Jung, K. ; Kretzschmar, B.; Bähr, M.   & Dechent, P.  et al.​ (2016) 
    PLoS ONE11(9) art. e0162583​.​ DOI: https://doi.org/10.1371/journal.pone.0162583 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons​
    Koch, J. C. ; Bitow, F.; Haack, J.; D'Hedouville, Z.; Zhang, J.-N.; Tönges, L.   & Michel, U.  et al.​ (2015) 
    Cell Death and Disease6 art. e1811​.​ DOI: https://doi.org/10.1038/cddis.2015.169 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​The indirect NMDAR inhibitor flupirtine induces sustained post-ischemic recovery, neuroprotection and angioneurogenesis​
    Jaeger, H. M.; Pehlke, J. R.; Kaltwasser, B.; Kilic, E. ; Bähr, M. ; Hermann, D. M. & Doeppner, T. R. ​ (2015) 
    Oncotarget6(16) pp. 14033​-14044​.​ DOI: https://doi.org/10.18632/oncotarget.4226 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition​
    Doeppner, T. R. ; Kaltwasser, B.; Schlechter, J.; Jaschke, J.; Kilic, E. ; Bähr, M.   & Hermann, D. M. et al.​ (2015) 
    Cell Death and Disease6 art. e2024​.​ DOI: https://doi.org/10.1038/cddis.2015.365 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation​
    Kunadt, M.; Eckermann, K.; Stuendl, A.; Gong, J.; Russo, B.; Strauss, K. & Rai, S. et al.​ (2015) 
    Acta Neuropathologica129(5) pp. 695​-713​.​ DOI: https://doi.org/10.1007/s00401-015-1408-1 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Systemic Escherichia coli infection does not influence clinical symptoms and neurodegeneration in experimental autoimmune encephalomyelitis​
    Kumar, P.; Friebe, K.; Schallhorn, R.; Moinfar, Z.; Nau, R. ; Bähr, M.   & Schütze, S. et al.​ (2015) 
    BMC Neuroscience16 art. 36​.​ DOI: https://doi.org/10.1186/s12868-015-0172-4 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53​
    Herold, S.; Kumar, P.; Wichert, S. P.; Kretzschmar, B.; Bähr, M. ; Rossner, M. J.   & Hein, K.​ (2015) 
    PLoS ONE10(10) art. e0138852​.​ DOI: https://doi.org/10.1371/journal.pone.0138852 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Effect of Beta-Blocker Therapy on the Risk of Infections and Death after Acute Stroke - A Historical Cohort Study​
    Maier, I. L. ; Karch, A. ; Mikolajczyk, R. T.; Bähr, M.   & Liman, J. ​ (2015) 
    PLoS ONE10(2) art. e0116836​.​ DOI: https://doi.org/10.1371/journal.pone.0116836 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice​
    Günther, R. ; Saal, K.-A. ; Suhr, M. ; Scheer, D.; Koch, J. C. ; Bähr, M.   & Lingor, P.  et al.​ (2014) 
    Frontiers in Neuroscience8 art. 304​.​ DOI: https://doi.org/10.3389/fnins.2014.00304 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model​
    Mlynarczuk-Bialy, I.; Doeppner, T. R. ; Golab, J.; Nowis, D.; Wilczynski, G. M.; Parobczak, K. & Wigand, M. E. et al.​ (2014) 
    Translational Oncology7(5) pp. 570​-579​.​ DOI: https://doi.org/10.1016/j.tranon.2014.07.002 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells​
    Koch, J. C. ; Tönges, L. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Frontiers in Cellular Neuroscience8 art. 273​.​ DOI: https://doi.org/10.3389/fncel.2014.00273 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Effects of acute versus post-acute systemic delivery of neural progenitor cells on neurological recovery and brain remodeling after focal cerebral ischemia in mice​
    Doeppner, T. R. ; Kaltwasser, B.; Teli, M. K.; Bretschneider, E. ; Bähr, M.   & Hermann, D. M.​ (2014) 
    Cell Death and Disease5 art. e1386​.​ DOI: https://doi.org/10.1038/cddis.2014.359 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease​
    Tönges, L. ; Szegö, E. M. ; Hause, P.; Saal, K.-A. ; Tatenhorst, L. ; Koch, J. C.   & D'Hedouville, Z. et al.​ (2014) 
    Frontiers in Aging Neuroscience6 art. UNSP 239​.​ DOI: https://doi.org/10.3389/fnagi.2014.00239 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Effects of neural progenitor cells on post-stroke neurological impairment-a detailed and comprehensive analysis of behavioral tests​
    Doeppner, T. R. ; Kaltwasser, B.; Bähr, M.   & Hermann, D. M.​ (2014) 
    Frontiers in Cellular Neuroscience8 art. 338​.​ DOI: https://doi.org/10.3389/fncel.2014.00338 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS​
    Koch, J. C. ; Tönges, L. ; Barski, E. ; Michel, U. ; Bähr, M.   & Lingor, P. ​ (2014) 
    Cell Death and Disease5 art. e1225​.​ DOI: https://doi.org/10.1038/cddis.2014.191 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Impact of the Cellular Prion Protein on Amyloid-beta and 3PO-Tau Processing​
    Schmitz, M.; Wulf, K.; Signore, S. C. ; Schulz-Schaeffer, W. J. ; Kermer, P. ; Baehr, M.   & Wouters, F. S.  et al.​ (2014) 
    Journal of Alzheimer's Disease38(3) pp. 551​-565​.​ DOI: https://doi.org/10.3233/JAD-130566 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper | 
    ​ ​Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease​
    Wagner, J. ; Ryazanov, S. ; Leonov, A. ; Levin, J.; Shi, S.; Schmidt, F. & Prix, C. et al.​ (2013) 
    Acta Neuropathologica125(6) pp. 795​-813​.​ DOI: https://doi.org/10.1007/s00401-013-1114-9 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper | 
    ​ ​Plaque morphology detected with Duplex ultrasound before carotid angioplasty and stenting (CAS) is not a predictor of carotid artery in-stent restenosis, a case control study​
    Wasser, K. ; Karch, A. ; Gröschel, S.; Witzenhausen, J. ; Gröschel, K.; Bähr, M.   & Liman, J. ​ (2013) 
    BMC Neurology13 art. 163​.​ DOI: https://doi.org/10.1186/1471-2377-13-163 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper | 
    ​ ​X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons​
    Dučić, T.; Barski, E. ; Salome, M.; Koch, J. C. ; Bähr, M.   & Lingor, P. ​ (2013) 
    Journal of Neurochemistry124(2) pp. 250​-261​.​ DOI: https://doi.org/10.1111/jnc.12073 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​HDAC1 Regulates Fear Extinction in Mice​
    Bahari-Javan, S. ; Maddalena, A.; Kerimoglu, C. ; Wittnam, J.; Held, T.; Bähr, M.   & Burkhardt, S.  et al.​ (2012) 
    The Journal of Neuroscience32(15) pp. 5062​-5073​.​ DOI: https://doi.org/10.1523/JNEUROSCI.0079-12.2012 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis​
    Koziolek, M. J. ; Tampe, D. ; Bähr, M. ; Dihazi, H. ; Jung, K. ; Fitzner, D. & Klingel, R. et al.​ (2012) 
    Journal of Neuroinflammation9 art. 80​.​ DOI: https://doi.org/10.1186/1742-2094-9-80 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery​
    Drinkut, A.; Tereshchenko, Y. ; Schulz, J. B. ; Bähr, M.   & Kügler, S. ​ (2012) 
    Molecular Therapy20(3) pp. 534​-543​.​ DOI: https://doi.org/10.1038/mt.2011.249 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease​
    Tönges, L. ; Frank, T. ; Tatenhorst, L. ; Saal, K. A. ; Koch, J. C. ; Szego, E. M.   & Bähr, M.  et al.​ (2012) 
    Brain135(11) pp. 3355​-3370​.​ DOI: https://doi.org/10.1093/brain/aws254 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Review | 
    ​ ​Axonal degeneration as a therapeutic target in the CNS​
    Lingor, P. ; Koch, J. C. ; Tönges, L.  & Bähr, M. ​ (2012)
    Cell and Tissue Research, 349​(1) pp. 289​-311​.​ DOI: https://doi.org/10.1007/s00441-012-1362-3 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | Research Paper | 
    ​ ​Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons​
    Taschenberger, G. ; Garrido, M.; Tereshchenko, Y. ; Baehr, M. ; Zweckstetter, M.   & Kügler, S. ​ (2012) 
    Acta Neuropathologica123(5) pp. 671​-683​.​ DOI: https://doi.org/10.1007/s00401-011-0926-8 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Review | 
    ​ ​ROCKing regeneration: Rho kinase inhibition as molecular target for neurorestoration​
    Tönges, L. ; Koch, J.-C. ; Bähr, M.  & Lingor, P. ​ (2011)
    Frontiers in Molecular Neuroscience, 4​.​ DOI: https://doi.org/10.3389/fnmol.2011.00039 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​JNK Isoforms Differentially Regulate Neurite Growth and Regeneration in Dopaminergic Neurons In Vitro​
    Tönges, L. ; Planchamp, V. ; Koch, J.-C. ; Herdegen, T.; Bähr, M.   & Lingor, P. ​ (2011) 
    Journal of Molecular Neuroscience45(2) pp. 284​-293​.​ DOI: https://doi.org/10.1007/s12031-011-9519-1 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​Sumoylation inhibits alpha-synuclein aggregation and toxicity​
    Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H.-H.; Bossis, G. & Urlaub, H.  et al.​ (2011) 
    The Journal of Cell Biology194(1) pp. 49​-60​.​ DOI: https://doi.org/10.1083/jcb.201010117 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons​
    Garrido, M.; Tereshchenko, Y. ; Zhevtsova, Z.; Taschenberger, G. ; Bähr, M.   & Kügler, S. ​ (2011) 
    Acta Neuropathologica121(4) pp. 475​-485​.​ DOI: https://doi.org/10.1007/s00401-010-0791-x 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper | 
    ​ ​Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia​
    Doeppner, T. R. ; Bretschneider, E. ; Doehring, M.; Segura, I.; Sentürk, A.; Acker-Palmer, A. & Hasan, M. R. et al.​ (2011) 
    Acta Neuropathologica122(4) pp. 429​-442​.​ DOI: https://doi.org/10.1007/s00401-011-0856-5 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper | 
    ​ ​Modulation of Huntingtin Toxicity by BAG1 is Dependent on an Intact BAG Domain​
    Liman, J. ; Sroka, K. ; Dohm, C. P. ; Deeg, S. ; Bähr, M.   & Kermer, P. ​ (2010) 
    Molecules15(10) pp. 6678​-6687​.​ DOI: https://doi.org/10.3390/molecules15106678 
    Details  DOI  WoS 
  • 2010 Journal Article | Research Paper | 
    ​ ​BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity​
    Deeg, S. ; Gralle, M. ; Sroka, K. ; Bähr, M. ; Wouters, F. S.   & Kermer, P. ​ (2010) 
    The Journal of Cell Biology188(4) pp. 505​-513​.​ DOI: https://doi.org/10.1083/jcb.200904103 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | 
    ​ ​The upregulation of GLAST-1 is an indirect antiapoptotic mechanism of GDNF and neurturin in the adult CNS​
    Koeberle, P. D. & Bähr, M. ​ (2008) 
    Cell Death and Differentiation15(3) pp. 471​-483​.​ DOI: https://doi.org/10.1038/sj.cdd.4402281 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper | 
    ​ ​Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle​
    Schmidt, J. ; Barthel, K.; Wrede, A.; Salajegheh, M.; Bähr, M.   & Dalakas, M. C.​ (2008) 
    Brain131(5) pp. 1228​-1240​.​ DOI: https://doi.org/10.1093/brain/awn053 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper | 
    ​ ​Mutant SOD1 detoxification mechanisms in intact single cells​
    Ganesan, S.; Rohde, G.; Eckermann, K.; Sroka, K. ; Schaefer, M. K. E.; Dohm, C. P.   & Kermer, P.  et al.​ (2008) 
    Cell Death and Differentiation15(2) pp. 312​-321​.​ DOI: https://doi.org/10.1038/sj.cdd.4402262 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper | 
    ​ ​Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen​
    Loh, S. H. Y.; Francescut, L.; Lingor, P. ; Bähr, M.   & Nicotera, P.​ (2008) 
    Cell Death and Differentiation15(2) pp. 283​-298​.​ DOI: https://doi.org/10.1038/sj.cdd.4402258 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper | 
    ​ ​Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis​
    Meuer, K. ; Suppanz, I. E. ; Lingor, P. ; Planchamp, V. ; Göricke, B.; Fichtner, L.   & Braus, G. H.  et al.​ (2007) 
    Cell Death and Differentiation14(4) pp. 651​-661​.​ DOI: https://doi.org/10.1038/sj.cdd.4402087 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper | 
    ​ ​NF-kappa B factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity​
    Pizzi, M.; Sarnico, I.; Boroni, F.; Benarese, M.; Steimberg, N.; Mazzoleni, G. & Dietz, G. P. H.  et al.​ (2005) 
    Cell Death and Differentiation12(7) art. 1362​.​ DOI: https://doi.org/10.1038/sj.cdd.4401598 10.1038/sj.cdd.4401742 
    Details  DOI; DOI  PMID  PMC  WoS; WoS 
  • 2004 Journal Article | Research Paper | 
    ​ ​The TAT Protein Transduction Domain Enhances the Neuroprotective Effect of Glial-Cell-Line-Derived Neurotrophic Factor after Optic Nerve Transection​
    Kilic, U.; Kilic, E. ; Dietz, G. P. H.   & Bähr, M. ​ (2004) 
    Neurodegenerative Diseases1(1) pp. 44​-49​.​ DOI: https://doi.org/10.1159/000076669 
    Details  DOI  PMID  PMC  WoS 
  • 2001 Journal Article | Research Paper | 
    ​ ​Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection​
    Weise, J.; Isenmann, S. & Bähr, M. ​ (2001) 
    Cell Death and Differentiation8(8) pp. 801​-807​.​ DOI: https://doi.org/10.1038/sj.cdd.4400872 
    Details  DOI  PMID  PMC  WoS 
  • 1999 Journal Article | Research Paper | 
    ​ ​Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma​
    Wagenknecht, B.; Glaser, T.; Naumann, U.; Kugler, S. ; Isenmann, S.; Bähr, M.   & Korneluk, R. G. et al.​ (1999) 
    Cell Death and Differentiation6(4) pp. 370​-376​.​ DOI: https://doi.org/10.1038/sj.cdd.4400503 
    Details  DOI  PMID  PMC  WoS 
  • 1999 Journal Article | Research Paper | 
    ​ ​Bax antisense oligonucleotides reduce axotomy-induced retinal ganglion cell death in vivo by reduction of Bax protein expression​
    Isenmann, S.; Engel, S.; Gillardon, F. & Bähr, M. ​ (1999) 
    Cell Death and Differentiation6(7) pp. 673​-682​.​ DOI: https://doi.org/10.1038/sj.cdd.4400538 
    Details  DOI  PMID  PMC  WoS 

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