Prof. Dr. Heike Bickeböller

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unigoe
 

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  • 2022 | Journal Article | Research Paper | 
    ​ ​ImputAccur: fast and user-friendly calculation of genotype-imputation accuracy-measures​
    Thormann, K. A.; Tozzi, V.; Starke, P.; Bickeböller, H. ; Baum, M.   & Rosenberger, A. ​ (2022) 
    BMC Bioinformatics, 23(1) art. 316​.​ DOI: https://doi.org/10.1186/s12859-022-04863-z 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk​
    Yang, W.; Liu, H.; Zhang, R.; Freedman, J. A.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2022) 
    npj Precision Oncology, 6(1).​ DOI: https://doi.org/10.1038/s41698-022-00281-9 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model​
    Hung, R. J.; Warkentin, M. T.; Brhane, Y.; Chatterjee, N.; Christiani, D. C.; Landi, M. T. & Caporaso, N. E. et al.​ (2021) 
    Cancer Research, 81(6) pp. 1607​-1615​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-20-1237 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper
    ​ ​I'am hiQ - A Novel Pair of Accuracy Indices for Imputed Genotypes​
    Rosenberger, A. ; Tozzi, V.; Baum, M. ; Thormann, K.; Hung, R. J.; Amos, C. I. & Bickeboeller, H. ​ (2021) 
    Genetic Epidemiology, 45(7) pp. 786​.​
    ​Details  WoS 
  • 2021 | Journal Article | Research Paper | 
    ​ ​A microRNA signature that correlates with cognition and is a target against cognitive decline​
    Islam, M. R.; Kaurani, L.; Berulava, T.; Heilbronner, U.; Budde, M.; Centeno, T. P. & Elerdashvili, V. et al.​ (2021) 
    EMBO Molecular Medicine, 13(11).​ DOI: https://doi.org/10.15252/emmm.202013659 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization​
    Zhou, W.; Liu, G.; Hung, R. J.; Haycock, P. C.; Aldrich, M. C.; Andrew, A. S. & Arnold, S. M. et al.​ (2020) 
    International Journal of Cancer, 148(5) pp. 1077​-1086​.​ DOI: https://doi.org/10.1002/ijc.33292 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Genome‐wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk​
    Dai, J.; Huang, M.; Amos, C. I.; Hung, R. J.; Tardon, A.; Andrew, A. & Chen, C. et al.​ (2020) 
    International Journal of Cancer, 146(10) pp. 2855​-2864​.​ DOI: https://doi.org/10.1002/ijc.32698 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation​
    Partanen, J.; Hyvärinen, K.; Bickeböller, H. ; Bogunia-Kubik, K.; Crossland, R. E.; Ivanova, M. & Perutelli, F. et al.​ (2020) 
    Frontiers in Immunology, 11.​ DOI: https://doi.org/10.3389/fimmu.2020.575492 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma​
    Qin, N.; Li, Y.; Wang, C.; Zhu, M.; Dai, J.; Hong, T. & Albanes, D. et al.​ (2020) 
    Frontiers of Medicine,.​ DOI: https://doi.org/10.1007/s11684-020-0779-4 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Association Analysis of Driver Gene–Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls​
    Wang, Y.; Gorlova, O. Y.; Gorlov, I. P.; Zhu, M.; Dai, J.; Albanes, D. & Lam, S. et al.​ (2020) 
    Cancer Epidemiology Biomarkers & Prevention, 29(7) pp. 1423​-1429​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-19-1085 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility​
    Kachuri, L.; Johansson, M.; Rashkin, S. R.; Graff, R. E.; Bossé, Y.; Manem, V. & Caporaso, N. E. et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-019-13855-2 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder​
    Budde, M.; Friedrichs, S.; Alliey-Rodriguez, N.; Ament, S.; Badner, J. A.; Berrettini, W. H. & Bloss, C. S. et al.​ (2019) 
    European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology, 29(1) pp. 156​-170​.​ DOI: https://doi.org/10.1016/j.euroneuro.2018.10.005 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Candidate-gene association analysis for a continuous phenotype with a spike at zero using parent-offspring trios​
    Klein, N. ; Entwistle, A.; Rosenberger, A. ; Kneib, T.   & Bickeböller, H. ​ (2019) 
    Journal of Applied Statistics, pp. 1​-15​.​ DOI: https://doi.org/10.1080/02664763.2019.1704226 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​S46A GENOME-WIDE ASSOCIATION STUDY OF THE LONGITUDINAL COURSE OF EXECUTIVE FUNCTIONS​
    Heilbronner, U.; Wendel, B.; Budde, M.; Gade, K.; Adorjan, K.; Kalman, J. & Senner, F. et al.​ (2019) 
    European Neuropsychopharmacology, 29 pp. S137​-S138​.​ DOI: https://doi.org/10.1016/j.euroneuro.2019.08.047 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​SU53A CROSS-DIAGNOSTIC GWAS OF LONGITUDINAL EXECUTIVE FUNCTION PROFILE SCORES​
    Heilbronner, U. ; Wendel, B.; Budde, M. ; Gade, K. ; Adorjan, K.; Kalman, J. & Senner, F. et al.​ (2019) 
    European Neuropsychopharmacology, 29 pp. S1295​-S1296​.​ DOI: https://doi.org/10.1016/j.euroneuro.2018.08.417 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Transcriptome-wide association study reveals candidate causal genes for lung cancer​
    Bossé, Y.; Li, Z.; Xia, J.; Manem, V.; Carreras-Torres, R.; Gabriel, A. & Gaudreault, N. et al.​ (2019) 
    International Journal of Cancer,.​ DOI: https://doi.org/10.1002/ijc.32771 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region​
    Hung, R. J.; Spitz, M. R.; Houlston, R. S.; Schwartz, A. G.; Field, J. K.; Ying, J. & Li, Y. et al.​ (2019) 
    Journal of Thoracic Oncology, 14(8) pp. 1360​-1369​.​ DOI: https://doi.org/10.1016/j.jtho.2019.04.008 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients​
    Papiol, S. ; Keeser, D.; Hasan, A.; Schneider-Axmann, T.; Raabe, F.; Degenhardt, F. & Rossner, M. J.  et al.​ (2019) 
    Translational Psychiatry, 9(1) art. 284​.​ DOI: https://doi.org/10.1038/s41398-019-0618-z 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Global, pathway and gene coverage of three Illumina arrays with respect to inflammatory and immune-related pathways​
    Tozzi, V.; Rosenberger, A. ; Kube, D. & Bickeböller, H. ​ (2019) 
    European Journal of Human Genetics, 27(11) pp. 1716​-1723​.​ DOI: https://doi.org/10.1038/s41431-019-0441-2 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis​
    Zhu, Y.; Wei, Y.; Zhang, R.; Dong, X.; Shen, S.; Zhao, Y. & Bai, J. et al.​ (2019) 
    Cancer Epidemiology, Biomarkers & Prevention, 28(5) pp. 935​-942​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-18-0356 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers​
    Kachuri, L.; Saarela, O.; Bojesen, S. E.; Davey Smith, G.; Liu, G.; Landi, M. T. & Caporaso, N. E et al.​ (2018) 
    International Journal of Epidemiology, 48(3) pp. 751​-766​.​ DOI: https://doi.org/10.1093/ije/dyy140 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners​
    Rosenberger, A. ; Hung, R. J.; Christiani, D. C.; Caporaso, N. E.; Liu, G.; Bojesen, S. E. & Le Marchand, L. et al.​ (2018) 
    International Archives of Occupational and Environmental Health, 91(8) pp. 937​-950​.​ DOI: https://doi.org/10.1007/s00420-018-1334-3 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Relating drug response to epigenetic and genetic markers using a region-based kernel score test​
    Yasmeen, S.; Burger, P.; Friedrichs, S.; Papiol, S. & Bickeböller, H. ​ (2018) 
    BMC Proceedings, 12(Suppl 9) art. 47​.​ DOI: https://doi.org/10.1186/s12919-018-0154-5 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity​
    Ferreiro-Iglesias, A.; Lesseur, C.; McKay, J.; Hung, R. J.; Han, Y.; Zong, X. & Christiani, D. et al.​ (2018) 
    Nature Communications, 9(1).​ DOI: https://doi.org/10.1038/s41467-018-05890-2 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Detecting responses to treatment with fenofibrate in pedigrees​
    Cherlin, S.; Wang, M. H.; Bickeböller, H.   & Cantor, R. M​ (2018) 
    BMC Genetics, 19(Suppl 1) art. 64​.​ DOI: https://doi.org/10.1186/s12863-018-0652-5 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Weighting Schemes in Pooled Linkage Analysis​
    Loesgen, S.; Dempfle, A.; Golla, A. & Bickeböller, H. ​ (2017) 
    Genetic Epidemiology, 21(S1) pp. S142​-S147​.​ DOI: https://doi.org/10.1002/gepi.2001.21.s1.s142 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer​
    Feng, Y.; Wang, Y.; Liu, H.; Liu, Z.; Mills, C.; Owzar, K. & Xie, J. et al.​ (2017) 
    Molecular Carcinogenesis, 57(2) pp. 216​-224​.​ DOI: https://doi.org/10.1002/mc.22748 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population​
    Li, Y.; Xiao, X.; Han, Y.; Gorlova, O.; Qian, D.; Leighl, N. & Johansen, J. S et al.​ (2017) 
    Carcinogenesis, 39(3) pp. 336​-346​.​ DOI: https://doi.org/10.1093/carcin/bgx113 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia​
    Gu, F.; Zhang, H.; Hyland, P. L.; Berndt, S.; Gapstur, S. M.; Wheeler, W. & ELLIPSE consortium, t. et al.​ (2017) 
    International Journal of Cancer, 141(9) pp. 1794​-1802​.​ DOI: https://doi.org/10.1002/ijc.30883 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers​
    Amos, C. I.; Dennis, J.; Wang, Z.; Byun, J.; Schumacher, F. R.; Gayther, S. A. & Casey, G. et al.​ (2017) 
    Cancer Epidemiology Biomarkers & Prevention, 26(1) pp. 126​-135​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-16-0106 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia​
    Papiol, S.; Popovic, D.; Keeser, D.; Hasan, A.; Schneider-Axmann, T.; Degenhardt, F. A. & Rossner, M. J. et al.​ (2017) 
    Translational Psychiatry, 7 art. e1159​.​ DOI: https://doi.org/10.1038/tp.2017.131 
    ​Details  DOI  WoS 
  • 2017 | Journal Article | 
    ​ ​Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.​
    Carreras-Torres, R.; Johansson, M.; Haycock, P. C.; Wade, K. H.; Relton, C. L.; Martin, R. M. & Davey Smith, G. et al.​ (2017) 
    PloS one, 12(6) art. e0177875​.​ DOI: https://doi.org/10.1371/journal.pone.0177875 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium​
    Feng, Y.; Wang, Y.; Liu, H.; Liu, Z.; Mills, C.; Han, Y. & Hung, R. J. et al.​ (2017) 
    Scientific Reports, 7 art. 825​.​ DOI: https://doi.org/10.1038/s41598-017-00850-0 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus​
    Yin, J.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2017) 
    Molecular Carcinogenesis, 56(6) pp. 1663​-1672​.​ DOI: https://doi.org/10.1002/mc.22622 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​Susceptibility Loci of CNOT6 in the General mRNA Degradation Pathway and Lung Cancer Risk-A Re-Analysis of Eight GWASs​
    Zhou, F.; Wang, Y.; Liu, H.; Ready, N.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2017) 
    Molecular Carcinogenesis, 56(4) pp. 1227​-1238​.​ DOI: https://doi.org/10.1002/mc.22585 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​Functional variants in DCAF4 associated with lung cancer risk in European populations​
    Liu, H.; Liu, Z.; Wang, Y.; Stinchcombe, T. E.; Owzar, K.; Han, Y. & Hung, R. J. et al.​ (2017) 
    Carcinogenesis, 38(5) pp. 541​-551​.​ DOI: https://doi.org/10.1093/carcin/bgx033 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs​
    Pan, Y.; Liu, H.; Wang, Y.; Kang, X.; Liu, Z.; Owzar, K. & Han, Y. et al.​ (2017) 
    Scientific Reports, 7 art. 44634​.​ DOI: https://doi.org/10.1038/srep44634 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus​
    Rosenberger, A. ; Sohns, M.; Friedrichs, S.; Hung, R. J.; Fehringer, G.; McLaughlin, J. R. & Amos, C. I. et al.​ (2017) 
    PLoS ONE, 12(3) art. e0173339​.​ DOI: https://doi.org/10.1371/journal.pone.0173339 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies​
    Friedrichs, S. ; Manitz, J. ; Burger, P.; Amos, C. I.; Risch, A.; Chang-Claude, J. & Wichmann, H.-E. et al.​ (2017) 
    Computational and mathematical methods in medicine, 2017 pp. 6742763​-17​.​ DOI: https://doi.org/10.1155/2017/6742763 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis​
    Chen, L.-S.; Baker, T.; Hung, R. J.; Horton, A.; Culverhouse, R.; Hartz, S. & Saccone, N. et al.​ (2016) 
    EBioMedicine, 11 pp. 219​-226​.​ DOI: https://doi.org/10.1016/j.ebiom.2016.08.012 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data​
    Malzahn, D.; Friedrichs, S. & Bickeböller, H. ​ (2016) 
    BMC Proceedings, 10 art. 17​.​ DOI: https://doi.org/10.1186/s12919-016-0042-9 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls (vol 132, pg 579, 2013)​
    Brenner, D. R.; Brennan, P. C.; Boffetta, P.; Amos, C. I.; Spitz, M. R.; Chen, C. & Goodman, G. et al.​ (2016) 
    Human Genetics, 135(8).​ DOI: https://doi.org/10.1007/s00439-016-1692-4 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses​
    Khankari, N. K.; Shu, X.-O.; Wen, W.; Kraft, P.; Lindstrom, S.; Peters, U. & Schildkraut, J. et al.​ (2016) 
    PLoS Medicine, 13(9) art. e1002118​.​ DOI: https://doi.org/10.1371/journal.pmed.1002118 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium​
    Wang, L.; Liu, H.; Liu, Z.; Yi, X.; Bickeboller, H. ; Hung, R. J. & Brennan, P. C. et al.​ (2016) 
    Carcinogenesis, 37(9) pp. 888​-896​.​ DOI: https://doi.org/10.1093/carcin/bgw070 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer​
    Yuan, H.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2016) 
    Scientific Reports, 6 art. 34234​.​ DOI: https://doi.org/10.1038/srep34234 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls​
    Kang, X.; Liu, H.; Onaitis, M. W.; Liu, Z.; Owzar, K.; Han, Y. & Su, L. I. et al.​ (2016) 
    Carcinogenesis, 37(3) pp. 280​-289​.​ DOI: https://doi.org/10.1093/carcin/bgw014 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Overview | 
    ​ ​Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks​
    Isernhagen, A.; Malzahn, D. ; Bickeboeller, H.   & Dressel, R. ​ (2016) 
    Frontiers in Immunology, 7 art. 588​.​ DOI: https://doi.org/10.3389/fimmu.2016.00588 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Impact of genomic risk factors on survival after haematopoietic stem cell transplantation for patients with acute leukaemia​
    Pearce, K. F.; Balavarca, Y.; Norden, J.; Jackson, G. H.; Holler, E.; Dressel, R. & Greinix, H. T. et al.​ (2016) 
    International Journal of Immunogenetics, 43(6) pp. 404​-412​.​ DOI: https://doi.org/10.1111/iji.12295 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk​
    Patel, Y. M.; Park, S. L.; Han, Y.; Wilkens, L. R.; Bickeböller, H. ; Rosenberger, A.   & Caporaso, N. et al.​ (2016) 
    Cancer Research, 76(19) pp. 5768​-5776​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-16-0446 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer​
    Hung, R. J.; Ulrich, C. M.; Goode, E. L.; Brhane, Y.; Muir, K.; Chan, A. T. & Le Marchand, L. et al.​ (2015) 
    JNCI Journal of the National Cancer Institute, 107(11) art. djv246​.​ DOI: https://doi.org/10.1093/jnci/djv246 
    ​Details  DOI  WoS 
  • 2015 | Journal Article
    ​ ​Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia​
    Brenner, D. R.; Amos, C. I.; Brhane, Y.; Timofeeva, M. N.; Caporaso, N.; Wang, Y. & Christiani, D. C. et al.​ (2015) 
    Carcinogenesis, 36(11) pp. 1314​-1326​.​ DOI: https://doi.org/10.1093/carcin/bgv128 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study​
    Zhang, C.; Doherty, J. A.; Burgess, S.; Hung, R. J.; Lindstroem, S.; Kraft, P. & Gong, J. et al.​ (2015) 
    Human Molecular Genetics, 24(18) pp. 5356​-5366​.​ DOI: https://doi.org/10.1093/hmg/ddv252 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence​
    Hancock, D. B.; Reginsson, G. W.; Gaddis, N. C.; Chen, X.; Saccone, N. L.; Lutz, S. M. & Qaiser, B. et al.​ (2015) 
    Translational Psychiatry, 5 art. e651​.​ DOI: https://doi.org/10.1038/tp.2015.149 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions​
    Qian, D. C.; Byun, J.; Han, Y.; Greene, C. S.; Field, J. K.; Hung, R. J. & Brhane, Y. et al.​ (2015) 
    Human Molecular Genetics, 24(25) pp. 7406​-7420​.​ DOI: https://doi.org/10.1093/hmg/ddv440 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies​
    Rosenberger, A. ; Friedrichs, S.; Amos, C. I.; Brennan, P. C.; Fehringer, G.; Heinrich, J. & Hung, R. J. et al.​ (2015) 
    PLoS ONE, 10(10) art. e0140179​.​ DOI: https://doi.org/10.1371/journal.pone.0140179 
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  • 2015 | Journal Article
    ​ ​Informed Genome-Wide Association Analysis With Family History As a Secondary Phenotype Identifies Novel Loci of Lung Cancer​
    Poirier, J. G.; Brennan, P. C.; McKay, J. D.; Spitz, M. R.; Bickeboeller, H. ; Risch, A. & Liu, G. et al.​ (2015) 
    Genetic Epidemiology, 39(3) pp. 197​-206​.​ DOI: https://doi.org/10.1002/gepi.21882 
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  • 2015 | Journal Article
    ​ ​Predicting survival using clinical risk scores and non-HLA immunogenetics​
    Balavarca, Y.; Pearce, K. F.; Norden, J.; Collin, M.; Jackson, G. H.; Holler, E. & Dressel, R. et al.​ (2015) 
    Bone Marrow Transplantation, 50(11) pp. 1445​-1452​.​ DOI: https://doi.org/10.1038/bmt.2015.173 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation​
    Isernhagen, A.; Malzahn, D. ; Viktorova, E.; Elsner, L.; Monecke, S.; von Bonin, F. & Kilisch, M. et al.​ (2015) 
    EMBO Molecular Medicine, 7(11) pp. 1480​-1502​.​ DOI: https://doi.org/10.15252/emmm.201505246 
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  • 2014 | Journal Article | 
    ​ ​Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia​
    Park, S. L.; Fesinmeyer, M. D.; Timofeeva, M. N.; Caberto, C. P.; Kocarnik, J. M.; Han, Y. & Love, S.-A. et al.​ (2014) 
    JNCI Journal of the National Cancer Institute, 106(4) art. dju061​.​ DOI: https://doi.org/10.1093/jnci/dju061 
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  • 2014 | Journal Article | 
    ​ ​Coverage and efficiency in current SNP chips​
    Ngoc-Thuy Ha, N. Ngoc-Thuy Ha, Ngoc-Thuy Ha; Freytag, S. & Bickeboeller, H. ​ (2014) 
    European Journal of Human Genetics, 22(9) pp. 1124​-1130​.​ DOI: https://doi.org/10.1038/ejhg.2013.304 
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  • 2014 | Journal Article
    ​ ​Comparison of three summary statistics for ranking genes in genome-wide association studies​
    Freytag, S. & Bickeboeller, H. ​ (2014) 
    Statistics in Medicine, 33(11) pp. 1828​-1841​.​ DOI: https://doi.org/10.1002/sim.6063 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies​
    Freytag, S.; Manitz, J. ; Schlather, M.; Kneib, T. ; Amos, C. I.; Risch, A. & Chang-Claude, J. et al.​ (2014) 
    Human Heredity, 76(2) pp. 64​-75​.​ DOI: https://doi.org/10.1159/000357567 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article
    ​ ​Genetic factors in individual radiation sensitivity​
    Hornhardt, S.; Roessler, U.; Sauter, W.; Rosenberger, A. ; Illig, T.; Bickeboeller, H.   & Wichmann, H.-E. et al.​ (2014) 
    DNA Repair, 16 pp. 54​-65​.​ DOI: https://doi.org/10.1016/j.dnarep.2014.02.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R​
    Malzahn, D. ; Mueller-Nurasyid, M.; Heid, I. M.; Wichmann, H.-E. & Bickeboeller, H. ​ (2014) 
    European Journal of Human Genetics, 22(10) pp. 1217​-1224​.​ DOI: https://doi.org/10.1038/ejhg.2014.3 
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  • 2013 | Journal Article | Letter Note
    ​ ​"Tradition Is not Preserving the Ashes, It Is Passing on the Fire" On Strengthening Ties with GMDS​
    Bickeboeller, H. ; Haux, R. & Winter, A.​ (2013) 
    METHODS OF INFORMATION IN MEDICINE, 52(1) pp. 1​-2​.​
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  • 2013 | Journal Article
    ​ ​Empirical Hierarchical Bayes Approach to Gene-Environment Interactions: Development and Application to Genome-Wide Association Studies of Lung Cancer in TRICL​
    Sohns, M.; Viktorova, E.; Amos, C. I.; Brennan, P. C.; Fehringer, G.; Gaborieau, V. & Han, Y. et al.​ (2013) 
    Genetic Epidemiology, 37(6) pp. 551​-559​.​ DOI: https://doi.org/10.1002/gepi.21741 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​A Novel Kernel for Correcting Size Bias in the Logistic Kernel Machine Test with an Application to Rheumatoid Arthritis​
    Freytag, S.; Bickeböller, H. ; Amos, C. I.; Kneib, T.   & Schlather, M.​ (2013) 
    Human Heredity, 74(2) pp. 97​-108​.​ DOI: https://doi.org/10.1159/000347188 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters​
    Kästner, A. ; Malzahn, D. ; Begemann, M. ; Hilmes, C.; Bickeböller, H.   & Ehrenreich, H. ​ (2013) 
    BMC Psychiatry, 13 art. 218​.​ DOI: https://doi.org/10.1186/1471-244X-13-218 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article
    ​ ​Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls​
    Brenner, D. R.; Brennan, P. C.; Boffetta, P.; Amos, C. I.; Spitz, M. R.; Chen, C. & Goodman, G. et al.​ (2013) 
    Human Genetics, 132(5) pp. 579​-589​.​ DOI: https://doi.org/10.1007/s00439-013-1270-y 
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  • 2012 | Journal Article
    ​ ​Novel Kernel for Correcting Significance Bias in the Logistic Kernel Machine Test with an Application to Rheumatoid Arthritis​
    Freytag, S.; Amos, C. I.; Bickeböller, H. ; Kneib, T.   & Schlather, M.​ (2012) 
    Human Heredity, 74 pp. 97​-108​.​
    ​Details 
  • 2012 | Journal Article
    ​ ​Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium​
    Rosenberger, A. ; Bickeboeller, H. ; McCormack, V.; Brenner, D. R.; Duell, E. J.; Tjonneland, A. & Friis, S. et al.​ (2012) 
    Carcinogenesis, 33(3) pp. 587​-597​.​ DOI: https://doi.org/10.1093/carcin/bgr307 
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  • 2012 | Journal Article | 
    ​ ​Comparison of Pathway Analysis Approaches Using Lung Cancer GWAS Data Sets​
    Fehringer, G.; Liu, G.; Briollais, L.; Brennan, P. C.; Amos, C. I.; Spitz, M. R. & Bickeboeller, H.  et al.​ (2012) 
    PLoS ONE, 7(2) art. e31816​.​ DOI: https://doi.org/10.1371/journal.pone.0031816 
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  • 2012 | Journal Article | 
    ​ ​Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls​
    Timofeeva, M. N.; Hung, R. J.; Rafnar, T.; Christiani, D. C.; Field, J. K.; Bickeboeller, H.   & Risch, A. et al.​ (2012) 
    Human Molecular Genetics, 21(22) pp. 4980​-4995​.​ DOI: https://doi.org/10.1093/hmg/dds334 
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  • 2012 | Journal Article | 
    ​ ​Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies​
    Zaitlen, N.; Lindstroem, S.; Pasaniuc, B.; Cornelis, M.; Genovese, G.; Pollack, S. & Barton, A. et al.​ (2012) 
    PLoS Genetics, 8(11) art. e1003032​.​ DOI: https://doi.org/10.1371/journal.pgen.1003032 
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  • 2012 | Journal Article | 
    ​ ​Heritability of Radiation Response in Lung Cancer Families​
    Rosenberger, A. ; Roessler, U.; Hornhardt, S.; Sauter, W.; Bickeboeller, H. ; Wichmann, H.-E. & Gomolka, M.​ (2012) 
    Genes, 3(2) pp. 248​-260​.​ DOI: https://doi.org/10.3390/genes3020248 
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  • 2012 | Journal Article
    ​ ​Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium​
    Cote, M. L.; Liu, M.; Bonassi, S.; Neri, M.; Schwartz, A. G.; Christiani, D. C. & Spitz, M. R. et al.​ (2012) 
    European Journal of Cancer, 48(13) pp. 1957​-1968​.​ DOI: https://doi.org/10.1016/j.ejca.2012.01.038 
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  • 2011 | Journal Article | 
    ​ ​Identifying rare variants from exome scans: the GAW17 experience​
    Ghosh, S.; Bickeböller, H. ; Bailey, J.; Bailey-Wilson, J. E.; Cantor, R.; Culverhouse, R. & Daw, W. et al.​ (2011) 
    BMC Proceedings, 5(Suppl 9) pp. S1​.​ DOI: https://doi.org/10.1186/1753-6561-5-S9-S1 
    ​Details  DOI 
  • 2011 | Journal Article | 
    ​ ​Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO)​
    McCormack, V. A.; Hung, R. J.; Brenner, D. R.; Bickeboeller, H. ; Rosenberger, A. ; Muscat, J. E. & Lazarus, P. et al.​ (2011) 
    Cancer Causes & Control, 22(12) pp. 1709​-1720​.​ DOI: https://doi.org/10.1007/s10552-011-9847-z 
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  • 2011 | Journal Article
    ​ ​Validation of a fully automated COMET assay: 1.75 million single cells measured over a 5 year period​
    Rosenberger, A. ; Roessler, U.; Hornhardt, S.; Sauter, W.; Bickeboeller, H. ; Wichmann, H.-E. & Gomolka, M.​ (2011) 
    DNA Repair, 10(3) pp. 322​-337​.​ DOI: https://doi.org/10.1016/j.dnarep.2010.12.003 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia​
    Papiol, S. ; Malzahn, D. ; Kästner, A. ; Sperling, S. ; Begemann, M. ; Stefansson, H. & Bickeböller, H.  et al.​ (2011) 
    Translational Psychiatry, 1(10) art. e45​.​ DOI: https://doi.org/10.1038/tp.2011.43 
    ​Details  DOI  PMID  PMC 
  • 2011 | Journal Article | Research Paper | 
    ​ ​A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia​
    Grube, S.; Gerchen, M. F.; Adamcio, B. ; Pardo, L. A. ; Martin, S. ; Malzahn, D.   & Papiol, S.  et al.​ (2011) 
    EMBO Molecular Medicine, 3(6) pp. 309​-319​.​ DOI: https://doi.org/10.1002/emmm.201100135 
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  • 2011 | Journal Article
    ​ ​Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction​
    Bickeboeller, H. ; Houwing-Duistermaat, J. J.; Wang, X. & Yan, X.​ (2011) 
    Genetic Epidemiology, 35 pp. S35​-S40​.​ DOI: https://doi.org/10.1002/gepi.20647 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms​
    Begemann, M. ; Grube, S.; Papiol, S. ; Malzahn, D. ; Krampe, H. ; Ribbe, K.   & Friedrichs, H.  et al.​ (2010) 
    Archives of General Psychiatry, 67(9) pp. 879​-888​.​ DOI: https://doi.org/10.1001/archgenpsychiatry.2010.107 
    ​Details  DOI 
  • 2010 | Journal Article | 
    ​ ​Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium​
    Truong, T.; Hung, R. J.; Amos, C. I.; Wu, X.; Bickeböller, H. ; Rosenberger, A.   & Sauter, W. et al.​ (2010) 
    JNCI Journal of the National Cancer Institute, 102(13) pp. 959​-971​.​ DOI: https://doi.org/10.1093/jnci/djq178 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​Inverse Relationship Between Cerebrovascular Lesions and Severity of Lewy Body Pathology in Patients With Lewy Body Diseases​
    Ghebremedhin, E.; Rosenberger, A. ; Rueb, U.; Vuksic, M.; Berhe, T.; Bickeboeller, H.   & de Vos, R. A. I. et al.​ (2010) 
    Journal of Neuropathology & Experimental Neurology, 69(5) pp. 442​-448​.​ DOI: https://doi.org/10.1097/NEN.0b013e3181d88e63 
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  • 2010 | Journal Article
    ​ ​Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer​
    Timofeeva, M. N.; Kropp, S.; Sauter, W.; Beckmann, L.; Rosenberger, A. ; Illig, T. & Jaeger, B. et al.​ (2010) 
    International Journal of Cancer, 127(7) pp. 1547​-1561​.​ DOI: https://doi.org/10.1002/ijc.25175 
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  • 2010 | Journal Article | Letter Note
    ​ ​GPC5 rs2352028 variant and risk of lung cancer in never smokers​
    Landi, M. T.; Chatterjee, N.; Caporaso, N. E.; Rotunno, M.; Albanes, D.; Thun, M. & Wheeler, W. et al.​ (2010) 
    The Lancet Oncology, 11(8) pp. 714​-716​.​ DOI: https://doi.org/10.1016/S1470-2045(10)70096-6 
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  • 2010 | Journal Article
    ​ ​The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells​
    Elsner, L.; Lozano, J. P.; Muppala, V.; Eiz-Vesper, B.; Demiroglu, S. Y. ; Malzahn, D.   & Herrmann, T. R. et al.​ (2010) 
    Journal of Cellular and Molecular Medicine, 14(4) pp. 992​-1002​.​ DOI: https://doi.org/10.1111/j.1582-4934.2008.00677.x 
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  • 2010 | Journal Article | Research Paper
    ​ ​A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy​
    Knöll, R.; Kostin, S.; Klede, S.; Savvatis, K.; Klinge, L. ; Stehle, I. & Gunkel, S. et al.​ (2010) 
    Circulation Research, 106(4) pp. 695​-704​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.109.206243 
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  • 2010 | Journal Article | Research Paper
    ​ ​Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia​
    Radyushkin, K.; El-Kordi, A. ; Boretius, S. ; Castaneda, S.; Ronnenberg, A.; Reim, K. & Bickeböller, H.  et al.​ (2010) 
    Genes, Brain and Behavior, 9(6) pp. 592​-602​.​ DOI: https://doi.org/10.1111/j.1601-183X.2010.00590.x 
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  • 2010 | Journal Article | 
    ​ ​Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia​
    Dickinson, A. M.; Pearce, K. F.; Norden, J.; O'Brien, S. G.; Holler, E.; Bickeboeller, H.   & Balavarca, Y. et al.​ (2010) 
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(6) pp. 922​-927​.​ DOI: https://doi.org/10.3324/haematol.2009.016220 
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  • 2010 | Journal Article | 
    ​ ​The Longitudinal Nonparametric Test as a New Tool to Explore Gene-Gene and Gene-Time Effects in Cohorts​
    Malzahn, D. ; Schillert, A.; Mueller, M. & Bickeboeller, H. ​ (2010) 
    Genetic Epidemiology, 34(5) pp. 469​-478​.​ DOI: https://doi.org/10.1002/gepi.20500 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​International Lung Cancer Consortium: Coordinated association study of 10 potential lung cancer susceptibility variants​
    Truong, T.; Sauter, W.; McKay, J. D.; Hosgood, H. D. I.; Gallagher, C.; Amos, C. I. & Spitz, M. R. et al.​ (2010) 
    Carcinogenesis, 31(4) pp. 625​-633​.​ DOI: https://doi.org/10.1093/carcin/bgq001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | 
    ​ ​Tests for candidate-gene interaction for longitudinal quantitative traits measured in a large cohort​
    Malzahn, D.; Balavarca, Y.; Lozano, J. P & Bickeböller, H. ​ (2009) 
    BMC Proceedings, 3(S7).​ DOI: https://doi.org/10.1186/1753-6561-3-S7-S80 
    ​Details  DOI 
  • 2009 | Journal Article | Research Paper | 
    ​ ​Integration of a priori gene set information into genome-wide association studies​
    Sohns, M. ; Rosenberger, A.   & Bickeböller, H. ​ (2009) 
    BMC Proceedings, 3(Suppl 7) art. S95​.​ DOI: https://doi.org/10.1186/1753-6561-3-S7-S95 
    ​Details  DOI 
  • 2009 | Journal Article | Research Paper | 
    ​ ​Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses​
    Cupples, L. A.; Beyene, J.; Bickeböller, H. ; Daw, E. W.; Fallin, M. D.; Gauderman, W. J. & Ghosh, S. et al.​ (2009) 
    BMC Proceedings, 3(Suppl 7) art. S1​.​ DOI: https://doi.org/10.1186/1753-6561-3-S7-S1 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences​
    Timofeeva, M. N.; Kropp, S.; Sauter, W.; Beckmann, L.; Rosenberger, A. ; Illig, T. & Jaeger, B. et al.​ (2009) 
    Carcinogenesis, 30(7) pp. 1161​-1169​.​ DOI: https://doi.org/10.1093/carcin/bgp102 
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  • 2009 | Journal Article
    ​ ​A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma​
    Landi, M. T.; Chatterjee, N.; Yu, K.; Goldin, L. R.; Goldstein, A. M.; Rotunno, M. & Mirabello, L. et al.​ (2009) 
    The American Journal of Human Genetics, 85(5) pp. 679​-691​.​ DOI: https://doi.org/10.1016/j.ajhg.2009.09.012 
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  • 2009 | Journal Article | Letter Note
    ​ ​Association of HLA-E Polymorphism With the Outcome of Hematopoietic Stem-Cell Transplantation With Unrelated Donors​
    Ludajic, K.; Rosenmayr, A.; Fae, I.; Fischer, G. F.; Balavarca, Y.; Bickeboeller, H.   & Kalhs, P. et al.​ (2009) 
    Transplantation Journal, 88(10) pp. 1227​-1228​.​ DOI: https://doi.org/10.1097/TP.0b013e3181bbb8fe 
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  • 2009 | Journal Article
    ​ ​KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation​
    Ludajic, K.; Balavarca, Y.; Bickeboeller, H. ; Rosenmayr, A.; Fae, I.; Fischer, G. F. & Kouba, M. et al.​ (2009) 
    Bone Marrow Transplantation, 44(2) pp. 97​-103​.​ DOI: https://doi.org/10.1038/bmt.2008.432 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​Minor ABO-Mismatches are Risk Factors for Acute Graft-versus-Host Disease in Hematopoietic Stem Cell Transplant Patients​
    Ludajic, K.; Balavarca, Y.; Bickeboeller, H. ; Rosenmayr, A.; Fischer, G. F.; Fae, I. & Kalhs, P. et al.​ (2009) 
    Biology of Blood and Marrow Transplantation, 15(11) pp. 1400​-1406​.​ DOI: https://doi.org/10.1016/j.bbmt.2009.07.002 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | 
    ​ ​Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity​
    Mertens, J.; Bregadze, R.; Mansur, A. ; Askar, E.; Bickeboeller, H. ; Ramadori, G. & Mihm, S.​ (2009) 
    Journal of Molecular Medicine, 87(8) pp. 815​-824​.​ DOI: https://doi.org/10.1007/s00109-009-0479-7 
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  • 2009 | Journal Article | 
    ​ ​GENESTAT: an information portal for design and analysis of genetic association studies​
    Ripatti, S.; Becker, T.; Bickeboeller, H. ; Dominicus, A.; Fischer, C.; Humphreys, K. & Jonasdottir, G. et al.​ (2009) 
    European Journal of Human Genetics, 17(4) pp. 533​-536​.​ DOI: https://doi.org/10.1038/ejhg.2008.216 
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  • 2009 | Journal Article
    ​ ​A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers​
    Timofeeva, M. N.; Jaeger, B.; Rosenberger, A. ; Sauter, W.; Wichmann, H.-E.; Bickeboeller, H.   & Risch, A.​ (2009) 
    Clinical Biochemistry, 42(6) pp. 500​-509​.​ DOI: https://doi.org/10.1016/j.clinbiochem.2008.12.011 
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  • 2008 | Journal Article
    ​ ​Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer​
    Sauter, W.; Rosenberger, A. ; Beckmann, L.; Kropp, S.; Mittelstrass, K.; Timofeeva, M. N. & Woelke, G. et al.​ (2008) 
    Cancer Epidemiology Biomarkers & Prevention, 17(5) pp. 1127​-1135​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-07-2840 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Quantifying the contribution of genetic variants for survival phenotypes​
    Mueller, M.; Doering, A.; Kuechenhoff, H.; Lamina, C.; Malzahn, D. ; Bickeboeller, H.   & Vollmert, C. et al.​ (2008) 
    Genetic Epidemiology, 32(6) pp. 574​-585​.​ DOI: https://doi.org/10.1002/gepi.20333 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Impact of HLA-DPB1 allelic and single amino acid mismatches on HSCT​
    Ludajic, K.; Balavarca, Y.; Bickeboeller, H. ; Pohlreich, D.; Kouba, M.; Dobrovolna, M. & Vrana, M. et al.​ (2008) 
    British Journal of Haematology, 142(3) pp. 436​-443​.​ DOI: https://doi.org/10.1111/j.1365-2141.2008.07177.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article | 
    ​ ​The Tumorigenicity of Mouse Embryonic Stem Cells and In Vitro Differentiated Neuronal Cells Is Controlled by the Recipients' Immune Response​
    Dressel, R.; Schindehuette, J.; Kuhlmann, T.; Elsner, L.; Novota, P.; Baier, P. C. & Schillert, A. et al.​ (2008) 
    PLoS ONE, 3(7) art. e2622​.​ DOI: https://doi.org/10.1371/journal.pone.0002622 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Correlation of Hsp70-1 and Hsp70-2 gene expression with the degree of graft-versus-host reaction in a rat skin explant model​
    Novota, P.; Sviland, L.; Zinocker, S.; Stocki, P.; Balavarca, Y.; Bickeboeller, H.   & Rolstad, B. et al.​ (2008) 
    Transplantation Journal, 85(12) pp. 1809​-1816​.​ DOI: https://doi.org/10.1097/TP.0b013e31817753f7 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Detection of ATM gene mutations in young lung cancer patients: A population-based control study​
    Schneider, J.; Illig, T.; Rosenberger, A. ; Bickeboeller, H.   & Wichmann, H.-E.​ (2008) 
    Archives of Medical Research, 39(2) pp. 226​-231​.​ DOI: https://doi.org/10.1016/j.arcmed.2007.08.004 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article | Research Paper | 
    ​ ​Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci​
    Cordell, H. J.; de Andrade, M.; Babron, M.-C.; Bartlett, C. W.; Beyene, J.; Bickeböller, H.   & Culverhouse, R. et al.​ (2007) 
    BMC Proceedings, 1(Suppl 1) art. S1​.​ DOI: https://doi.org/10.1186/1753-6561-1-S1-S1 
    ​Details  DOI 
  • 2007 | Journal Article | 
    ​ ​Case-control studies with affected sibships​
    Köhler, K.; Sohns, M. & Bickeböller, H. ​ (2007) 
    BMC Proceedings, 1(Suppl 1) art. S29​.​ DOI: https://doi.org/10.1186/1753-6561-1-s1-s29 
    ​Details  DOI 
  • 2007 | Journal Article
    ​ ​German cattle allergy study (CAS): public health relevance of cattle-allergic farmers​
    Heutelbeck, A. R. R.; Janicke, N.; Hilgers, R. ; Kutting, B.; Drexler, H. G.; Hallier, E. & Bickeboeller, H. ​ (2007) 
    International Archives of Occupational and Environmental Health, 81(2) pp. 201​-208​.​ DOI: https://doi.org/10.1007/s00420-007-0207-y 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​The Heat Shock Protein HSP70 Promotes Mouse NK Cell Activity against Tumors That Express Inducible NKG2D Ligands​
    Elsner, L.; Muppala, V.; Gehrmann, M.; Lozano, J.; Malzahn, D.; Bickeböller, H.   & Brunner, E. et al.​ (2007) 
    The Journal of Immunology, 179(8) pp. 5523​-5533​.​ DOI: https://doi.org/10.4049/jimmunol.179.8.5523 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​Strategy for detecting susceptibility genes with weak or no marginal effect​
    Kotti, S.; Bickeboeller, H.   & Clerget-Darpoux, F.​ (2007) 
    Human Heredity, 63(2) pp. 85​-92​.​ DOI: https://doi.org/10.1159/000099180 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article | 
    ​ ​Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease​
    Rosenberger, A. ; Sharma, M.; Mueller-Myhsok, B.; Gasser, T. & Bickeboeller, H. ​ (2007) 
    BMC Genetics, 8 art. 44​.​ DOI: https://doi.org/10.1186/1471-2156-8-44 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article
    ​ ​Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection​
    Wietzke-Braun, P.; Maouzi, A. B.; Maenhardt, L. B.; Bickeboeller, H. ; Ramadori, G. & Mihm, S.​ (2006) 
    European Journal of Gastroenterology & Hepatology, 18(9) pp. 991​-997​.​ DOI: https://doi.org/10.1097/01.meg.0000224478.89545.76 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article
    ​ ​Case-control association tests correcting for population stratification​
    Kohler, K. & Bickeboeller, H. ​ (2006) 
    Annals of Human Genetics, 70 pp. 98​-115​.​ DOI: https://doi.org/10.1111/j.1529-8817.2005.00214.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | 
    ​ ​Hidden population substructures in an apparently homogeneous population bias association studies​
    Berger, M.; Stassen, H. H.; Kohler, K.; Krane, V.; Monks, D.; Wanner, C. & Hoffmann, K. et al.​ (2006) 
    European Journal of Human Genetics, 14(2) pp. 236​-244​.​ DOI: https://doi.org/10.1038/sj.ejhg.5201546 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article
    ​ ​Relationship of Apolipoprotein E and Age at Onset to Parkinson Disease Neuropathology​
    Ghebremedhin, E.; Tredici, K. D.; Vuksic, M.; Rüb, U.; Thal, D. R; Burbach, G. J & Rosenberger, A.  et al.​ (2006) 
    Journal of Neuropathology and Experimental Neurology, 65(2) pp. 116​-123​.​ DOI: https://doi.org/10.1097/01.jnen.0000199572.96472.1c 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article
    ​ ​Significant association of a M129V independent polymorphism in the 5 ' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study​
    Vollmert, C.; Windl, O.; Xiang, W.; Rosenberger, A. ; Zerr, I.; Wichmann, H.-E. & Bickeboeller, H.  et al.​ (2006) 
    Journal of Medical Genetics, 43(10) art. e53​.​ DOI: https://doi.org/10.1136/jmg.2006.040931 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article
    ​ ​A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease​
    Riemenschneider, M.; Konta, L.; Friedrich, P.; Schwarz, S.; Taddei, K.; Neff, F. & Padovani, A. et al.​ (2006) 
    Human Molecular Genetics, 15(16) pp. 2446​-2456​.​ DOI: https://doi.org/10.1093/hmg/ddl167 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article
    ​ ​Systematic search of susceptibility loci with methods using gametic disequilibrium​
    Bickeböller, H. ; Margaritte-Jeannin, P.; Babron, M.-C. & Clerget-Darpoux, F.​ (2005) 
    Genetic Epidemiology, 12(6) pp. 577​-582​.​ DOI: https://doi.org/10.1002/gepi.1370120609 
    ​Details  DOI 
  • 2005 | Journal Article
    ​ ​Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers​
    Bickeböller, H.   & Clerget-Darpoux, F.​ (2005) 
    Genetic Epidemiology, 12(6) pp. 865​-870​.​ DOI: https://doi.org/10.1002/gepi.1370120656 
    ​Details  DOI 
  • 2005 | Journal Article
    ​ ​Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test​
    Clerget-Darpoux, F.; Babron, M.-C. & Bickeböller, H. ​ (2005) 
    Genetic Epidemiology, 12(6) pp. 583​-588​.​ DOI: https://doi.org/10.1002/gepi.1370120610 
    ​Details  DOI 
  • 2005 | Journal Article | Research Paper
    ​ ​NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity​
    Wojnowski, L.; Kulle, B.; Schirmer, M. ; Schlüter, G.; Schmidt, A.; Rosenberger, A.   & Vonhof, S. et al.​ (2005) 
    Circulation, 112(24) pp. 3754​-3762​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.576850 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Letter Note | 
    ​ ​Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans​
    Bailey-Wilson, J. E.; Almasy, L.; de Andrade, M.; Bailey, J. A.; Bickeboeller, H. ; Cordell, H. J. & Daw, E. W. et al.​ (2005) 
    BMC Genetics, 6 art. S1​.​ DOI: https://doi.org/10.1186/1471-2156-6-S1-S1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Application of genomewide SNP arrays for detection of simulated susceptibility loci​
    Kulle, B.; Schirmer, M. ; Toliat, M. R.; Suk, A.; Becker, C.; Tzvetkov, M.   & Brockmöller, J.  et al.​ (2005) 
    Human Mutation, 25(6) pp. 557​-565​.​ DOI: https://doi.org/10.1002/humu.20174 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article
    ​ ​High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11​
    Berger, M.; Mattheisen, M.; Kulle, B.; Schmidt, H.; Oldenburg, J.; Bickeboeller, H.   & Walter, U. et al.​ (2005) 
    Blood, 105(2) pp. 638​-644​.​ DOI: https://doi.org/10.1182/blood-2004-05-2018 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Angiotensin converting enzyme gene polymorphism and myocardial infarction a large association and linkage study​
    Holmer, S. R.; Bickeboeller, H. ; Hengstenberg, C.; Rohlmann, F.; Engel, S.; Lowel, H. & Mayer, B. et al.​ (2003) 
    The International Journal of Biochemistry & Cell Biology, 35(6) art. PII S1357-2725(02)00261-3​.​ DOI: https://doi.org/10.1016/S1357-2725(02)00261-3 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Journal Article
    ​ ​Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes​
    Immervoll, T.; Loesgen, S.; Dütsch, G.; Gohlke, H.; Herbon, N.; Klugbauer, S. & Dempfle, A. et al.​ (2001) 
    Human Mutation, 18(4) pp. 327​-336​.​ DOI: https://doi.org/10.1002/humu.1194 
    ​Details  DOI 
  • 2000 | Journal Article | Research Paper
    ​ ​Investigation of Linkage and Association: Issues on Study Design​
    Bickeböller, H. ​ (2000) 
    International Statistical Review, 68(1) pp. 75​.​ DOI: https://doi.org/10.2307/1403558 
    ​Details  DOI 
  • 2000 | Journal Article
    ​ ​Association of β 2 -Adrenoreceptor Variants with Bronchial Hyperresponsiveness​
    ULBRECHT, M.; HERGETH, M.; WJST, M.; HEINRICH, J.; Bickeböller, H. ; WICHMANN, H.-E. & WEISS, E.​ (2000) 
    American Journal of Respiratory and Critical Care Medicine, 161(2) pp. 469​-474​.​ DOI: https://doi.org/10.1164/ajrccm.161.2.9902072 
    ​Details  DOI 
  • 1999 | Journal Article | 
    ​ ​Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians​
    Scholz, M.; Kraft, H.-G.; Lingenhel, A.; Delport, R.; Vorster, E. H; Bickeböller, H.   & Utermann, G.​ (1999) 
    European Journal of Human Genetics, 7(2) pp. 169​-178​.​ DOI: https://doi.org/10.1038/sj.ejhg.5200290 
    ​Details  DOI 
  • 1997 | Journal Article
    ​ ​Investigation of the candidate genes ACTHR and Golf for bipolar illness by the transmission/disequilibrium test​
    Bickeböller, H. ; Kistler, M. & Scholz, M.​ (1997) 
    Genetic Epidemiology, 14(6) pp. 575​-580​.​ DOI: https://doi.org/10.1002/(SICI)1098-2272(1997)14:6<575::AID-GEPI4>3.0.CO;2-Z 
    ​Details  DOI 
  • 1996 | Journal Article
    ​ ​Distribution of Genome Shared IBD by Half-Sibs: Approximation by the Poisson Clumping Heuristic​
    Bickeböller, H.   & Thompson, E. A.​ (1996) 
    Theoretical Population Biology, 50(1) pp. 66​-90​.​ DOI: https://doi.org/10.1006/tpbi.1996.0023 
    ​Details  DOI 

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