Prof. Dr. med. Lars Siegfried Maier

 
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  • 2022 Journal Article
    ​ ​Na v 1.8 Dysregulates Na and Ca Leading to Arrhythmias in Patients with Sleep-disordered Breathing​
    Lebek, S.; Hegner, P.; Hultsch, R.; Rohde, J.; Rupprecht, L.; Schmid, C. & Sossalla, S. T.  et al.​ (2022) 
    American Journal of Respiratory and Critical Care Medicine, art. rccm.202205-0981LE​.​ DOI: https://doi.org/10.1164/rccm.202205-0981LE 
    Details  DOI 
  • 2022 Journal Article
    ​ ​Atrial Fibrillation Burden Specifically Determines Human Ventricular Cellular Remodeling​
    Körtl, T.; Stehle, T.; Riedl, D.; Trausel, J.; Rebs, S. ; Pabel, S.   & Paulus, M. et al.​ (2022) 
    JACC: Clinical Electrophysiology8(11) pp. 1357​-1366​.​ DOI: https://doi.org/10.1016/j.jacep.2022.07.016 
    Details  DOI 
  • 2021 Journal Article
    ​ ​Phosphorylation of RyR2 Ser‐2814 by CaMKII mediates β1‐adrenergic stress induced Ca 2+ ‐leak from the sarcoplasmic reticulum​
    Baier, M. J.; Noack, J.; Seitz, M. T.; Maier, L. S.   & Neef, S.​ (2021) 
    FEBS Open Bio, art. 2211-5463.13274​.​ DOI: https://doi.org/10.1002/2211-5463.13274 
    Details  DOI 
  • 2021 Journal Article
    ​ ​CaMKII δ Met281/282 oxidation is not required for recovery of calcium transients during acidosis​
    Kreitmeier, K. G.; Tarnowski, D.; Nanadikar, M. S.; Baier, M. J.; Wagner, S. ; Katschinski, D. M.   & Maier, L. S.  et al.​ (2021) 
    American Journal of Physiology-Heart and Circulatory Physiology320(3) pp. H1199​-H1212​.​ DOI: https://doi.org/10.1152/ajpheart.00040.2020 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation​
    Kolijn, D.; Pabel, S. ; Tian, Y.; Lódi, M.; Herwig, M.; Carrizzo, A. & Zhazykbayeva, S. et al.​ (2020) 
    Cardiovascular Research117(2) pp. 495​-507​.​ DOI: https://doi.org/10.1093/cvr/cvaa123 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart​
    Trum, M.; Islam, M. M. T.; Lebek, S.; Baier, M.; Hegner, P.; Eaton, P. & Maier, L. S.  et al.​ (2020) 
    American Journal of Physiology-Heart and Circulatory Physiology319(6) pp. H1347​-H1357​.​ DOI: https://doi.org/10.1152/ajpheart.00182.2020 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias​
    Pabel, S. ; Mustroph, J.; Stehle, T.; Lebek, S.; Dybkova, N.; Keyser, A. & Rupprecht, L. et al.​ (2020) 
    Europace22(7) pp. 1111​-1118​.​ DOI: https://doi.org/10.1093/europace/euaa079 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Contribution of the neuronal sodium channel NaV1.8 to sodium- and calcium-dependent cellular proarrhythmia​
    Bengel, P. ; Ahmad, S. ; Tirilomis, P.; Trum, M.; Dybkova, N.; Wagner, S.   & Maier, L. S.  et al.​ (2020) 
    Journal of Molecular and Cellular Cardiology144 pp. 35​-46​.​ DOI: https://doi.org/10.1016/j.yjmcc.2020.05.002 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Long-term effects of a standardized feedback-driven quality improvement program for timely reperfusion therapy in regional STEMI care networks​
    Scholz, K. H.; Lengenfelder, B.; Jacobshagen, C. ; Fleischmann, C.; Moehlis, H.; Olbrich, H. G & Jung, J. et al.​ (2020) 
    European Heart Journal. Acute Cardiovascular Care,.​ DOI: https://doi.org/10.1177/2048872620907323 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Dysferlin links excitation-contraction coupling to structure and maintenance of the cardiac transverse-axial tubule system​
    Hofhuis, J. ; Bersch, K.; Wagner, S. ; Molina, C. E. ; Fakuade, F. E.; Iyer, L. M.   & Streckfuß-Bömeke, K.  et al.​ (2020) 
    Europace22(7) pp. 1119​-1131​.​ DOI: https://doi.org/10.1093/europace/euaa093 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect​
    Reil, J.; Reil, G.; Kovács, Á.; Sequeira, V.; Waddingham, M. T.; Lodi, M. & Herwig, M. et al.​ (2020) 
    The Journal of Physiology598(15) pp. 3129​-3153​.​ DOI: https://doi.org/10.1113/JP279607 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice​
    Pabel, S. ; Ahmad, S. ; Tirilomis, P.; Stehle, T.; Mustroph, J.; Knierim, M. & Dybkova, N. et al.​ (2020) 
    Basic Research in Cardiology115(2).​ DOI: https://doi.org/10.1007/s00395-020-0780-8 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy​
    Ahmad, S. ; Tirilomis, P.; Pabel, S. ; Dybkova, N.; Hartmann, N. ; Molina, C. E.   & Tirilomis, T.  et al.​ (2019) 
    ESC Heart Failure6(1) pp. 154​-163​.​ DOI: https://doi.org/10.1002/ehf2.12378 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes​
    Mustroph, J.; Wagemann, O.; Lücht, C. M.; Trum, M.; Hammer, K. P.; Sag, C. M. & Lebek, S. et al.​ (2018) 
    ESC Heart Failure5(4) pp. 642​-648​.​ DOI: https://doi.org/10.1002/ehf2.12336 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy​
    Olivotto, I.; Camici, P. G.; Merlini, P. A.; Rapezzi, C.; Patten, M.; Climent, V. & Sinagra, G. et al.​ (2018) 
    Circulation: Heart Failure11(1).​ DOI: https://doi.org/10.1161/CIRCHEARTFAILURE.117.004124 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor​
    Neef, S.; Steffens, A.; Pellicena, P.; Mustroph, J.; Lebek, S.; Ort, K. R. & Schulman, H. et al.​ (2018) 
    Journal of Molecular and Cellular Cardiology115 pp. 73​-81​.​ DOI: https://doi.org/10.1016/j.yjmcc.2017.12.015 
    Details  DOI 
  • 2018 Journal Article | Research Paper
    ​ ​Empagliflozin directly improves diastolic function in human heart failure​
    Pabel, S. ; Wagner, S. ; Bollenberg, H.; Bengel, P. ; Kovács, Á.; Schach, C. & Tirilomis, P. et al.​ (2018) 
    European Journal of Heart Failure20(12) pp. 1690​-1700​.​ DOI: https://doi.org/10.1002/ejhf.1328 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart​
    Dybkova, N.; Ahmad, S. ; Pabel, S. ; Tirilomis, P.; Hartmann, N. ; Fischer, T. H   & Bengel, P.  et al.​ (2018) 
    Cardiovascular Research114(13) pp. 1728​-1737​.​ DOI: https://doi.org/10.1093/cvr/cvy152 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure​
    Fischer, T. H. ; Eiringhaus, J. ; Dybkova, N.; Saadatmand, A.; Pabel, S. ; Weber, S. & Wang, Y. et al.​ (2018) 
    European Journal of Heart Failure20(12) pp. 1673​-1685​.​ DOI: https://doi.org/10.1002/ejhf.1297 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article
    ​ ​Modulation of Cardiac Function by Oxidized Type I Protein Kinase A​
    Towhidul Islam, M M; Eaton, P.; Maier, L.   & Wagner, S. ​ (2017) 
    Free Radical Biology and Medicine112 pp. 123​-124​.​ DOI: https://doi.org/10.1016/j.freeradbiomed.2017.10.187 
    Details  DOI 
  • 2017 Journal Article | Research Paper
    ​ ​PP1 activation as novel antiarrhythmic approach in human heart failure​
    Eiringhaus, J. ; Fischer, T. H. ; Kohn, M.; Wang, Y.; Maier, L. S. ; Hasenfuss, G.   & Sossalla, S. T. ​ (2017) 
    European Heart Journal38(suppl_1) art. P5841​.​ DOI: https://doi.org/10.1093/eurheartj/ehx493.P5841 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart​
    Molina, C. E ; Jacquet, E.; Ponien, P.; Muñoz-Guijosa, C.; Baczkó, I.; Maier, L. S   & Donzeau-Gouge, P. et al.​ (2017) 
    Cardiovascular Research114(2) pp. 247​-258​.​ DOI: https://doi.org/10.1093/cvr/cvx182 
    Details  DOI 
  • 2017 Journal Article
    ​ ​CaMKII oxidation causes increased atrial fibrillation in diabetic mice​
    Mesubi, O.; Rokita, A.; Abrol, N.; Wu, Y.; Chen, B.; Wang, Q. & Granger, J. et al.​ (2017) 
    Journal of Molecular and Cellular Cardiology112 pp. 161​-162​.​ DOI: https://doi.org/10.1016/j.yjmcc.2017.07.092 
    Details  DOI 
  • 2017 Journal Article
    ​ ​PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock​
    Thiele, H.; Akin, I.; Sandri, M.; Fuernau, G.; de Waha, S.; Meyer-Saraei, R. & Nordbeck, P. et al.​ (2017) 
    New England Journal of Medicine377(25) pp. 2419​-2432​.​ DOI: https://doi.org/10.1056/nejmoa1710261 
    Details  DOI 
  • 2017 Journal Article | Research Paper | 
    ​ ​Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4​
    Perera, R. K. ; Fischer, T. H. ; Wagner, M.; Dewenter, M. ; Vettel, C. ; Bork, N. I. & Maier, L. S.  et al.​ (2017) 
    Scientific Reports7(1) art. 15222​.​ DOI: https://doi.org/10.1038/s41598-017-15632-x 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy​
    Hofhuis, J. ; Bersch, K.; Büssenschütt, R.; Drzymalski, M.; Liebetanz, D. ; Nikolaev, V. O.   & Wagner, S.  et al.​ (2017) 
    Journal of Cell Science130(5) pp. 841​-852​.​ DOI: https://doi.org/10.1242/jcs.198861 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure​
    Dewenter, M. ; Neef, S.; Vettel, C. ; Lämmle, S.; Beushausen, C.; Zelarayan, L. C.   & Katz, S. et al.​ (2017) 
    Circulation: Heart Failure10(5) art. e003840​.​ DOI: https://doi.org/10.1161/CIRCHEARTFAILURE.117.003840 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity​
    Neef, S.; Heijman, J.; Otte, K.; Dewenter, M. ; Saadatmand, A. R.; Meyer-Roxlau, S.   & Antos, C. L. et al.​ (2017) 
    Naunyn-Schmiedeberg's Archives of Pharmacology390(8) pp. 857​-862​.​ DOI: https://doi.org/10.1007/s00210-017-1376-1 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article | Research Paper
    ​ ​Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure​
    Fischer, T. H. ; Herting, J. ; Eiringhaus, J. ; Pabel, S. ; Hartmann, N. H. ; Ellenberger, D.   & Friedrich, M.  et al.​ (2016) 
    EP Europace18(9) pp. 1440​-1448​.​ DOI: https://doi.org/10.1093/europace/euv313 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII​
    Fischer, T. H. ; Herting, J. ; Mason, F. E. ; Hartmann, N. ; Watanabe, S.; Nikolaev, V. O.   & Sprenger, J. U. et al.​ (2015) 
    Cardiovascular Research107(1) pp. 184​-196​.​ DOI: https://doi.org/10.1093/cvr/cvv153 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy​
    Kreussner, M. M.; Lehmann, L. H.; Keranov, S.; Hoting, M.-O.; Oehl, U.; Kohlhaas, M. & Reil, J.-C. et al.​ (2014) 
    Circulation130(15) pp. 1262​-1273​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.114.006185 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article | Overview | 
    ​ ​CaMKII regulation of cardiac K channels​
    Mustroph, J.; Maier, L. S.   & Wagner, S.​ (2014) 
    Frontiers in Pharmacology5 art. 20​.​ DOI: https://doi.org/10.3389/fphar.2014.00020 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Overview
    ​ ​Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology​
    Köhler, A. C.; Sag, C. M. & Maier, L. S. ​ (2014) 
    Journal of Molecular and Cellular Cardiology73 pp. 92​-102​.​ DOI: https://doi.org/10.1016/j.yjmcc.2014.03.001 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article | Research Paper
    ​ ​Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner​
    Sag, C. M.; Mallwitz, A.; Wagner, S. ; Hartmann, N. ; Schotola, H.; Fischer, T. H.   & Ungeheuer, N. et al.​ (2014) 
    Journal of Molecular and Cellular Cardiology76 pp. 94​-105​.​ DOI: https://doi.org/10.1016/j.yjmcc.2014.08.016 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper | 
    ​ ​Enhanced Ca2+ influx through cardiac L-type Ca2+ channels maintains the systolic Ca2+ transient in early cardiac atrophy induced by mechanical unloading​
    Schwoerer, A. P.; Neef, S.; Broichhausen, I.; Jacubeit, J.; Tiburcy, M. ; Wagner, M. & Biermann, D. et al.​ (2013) 
    Pflügers Archiv - European Journal of Physiology465(12) pp. 1763​-1773​.​ DOI: https://doi.org/10.1007/s00424-013-1316-y 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Overview
    ​ ​Redox Regulation of Sodium and Calcium Handling​
    Wagner, S.; Rokita, A. G.; Anderson, M. E. & Maier, L. S. ​ (2013) 
    Antioxidants & Redox Signaling18(9) pp. 1063​-1077​.​ DOI: https://doi.org/10.1089/ars.2012.4818 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Overview
    ​ ​Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes​
    Sag, C. M.; Wagner, S.   & Maier, L. S. ​ (2013) 
    Free Radical Biology and Medicine63 pp. 338​-349​.​ DOI: https://doi.org/10.1016/j.freeradbiomed.2013.05.035 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Diabetes increases mortality after myocardial infarction by oxidizing CaMKII​
    Luo, M.; Guan, X.; Luczak, E. D.; Lang, D.; Kutschke, W.; Gao, Z. & Yang, J. et al.​ (2013) 
    Journal of Clinical Investigation123(3) pp. 1262​-1274​.​ DOI: https://doi.org/10.1172/JCI65268 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation​
    Purohit, A.; Rokita, A. G.; Guan, X.; Chen, B.; Koval, O. M.; Voigt, N.   & Neef, S. et al.​ (2013) 
    Circulation128(16) pp. 1748​-1757​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.113.003313 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Phosphodiesterase-2 Is Up-Regulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes​
    Mehel, H.; Emons, J.; Vettel, C. ; Wittköpper, K.; Seppelt, D.; Dewenter, M.   & Lutz, S.  et al.​ (2013) 
    Journal of the American College of Cardiology62(17) pp. 1596​-1606​.​ DOI: https://doi.org/10.1016/j.jacc.2013.05.057 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Overview
    ​ ​Novel aspects of excitation-contraction coupling in heart failure​
    Neef, S. & Maier, L. S. ​ (2013) 
    Basic Research in Cardiology108(4) art. 360​.​ DOI: https://doi.org/10.1007/s00395-013-0360-2 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease​
    Toischer, K. ; Hartmann, N. ; Wagner, S. ; Fischer, T. H. ; Herting, J. ; Danner, B. C.   & Sag, C. M. et al.​ (2013) 
    Journal of Molecular and Cellular Cardiology61 pp. 111​-122​.​ DOI: https://doi.org/10.1016/j.yjmcc.2013.03.021 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​RAnoLazIne for the Treatment of Diastolic Heart Failure in Patients With Preserved Ejection Fraction: ​The RALI-DHF Proof-of-Concept Study​
    Maier, L. S. ; Layug, B.; Karwatowska-Prokopczuk, E.; Belardinelli, L.; Lee, S.; Sander, J. & Lang, C. et al.​ (2013) 
    JACC: Heart Failure1(2) pp. 115​-122​.​ DOI: https://doi.org/10.1016/j.jchf.2012.12.002 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article
    ​ ​Influence of the Novel Inotropic Agent Levosimendan on Isometric Tension and Calcium Cycling in Failing Human Myocardium​
    Hasenfuss, G. ; Pieske, B. ; Castell, M. ; Kretschmann, B. ; Maier, L. S.   & Just, H. ​ (2012) 
    Circulation98(20) pp. 2141​-2147​.​ DOI: https://doi.org/10.1161/01.cir.98.20.2141 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Functional Effects of Endothelin and Regulation of Endothelin Receptors in Isolated Human Nonfailing and Failing Myocardium​
    Pieske, B. ; Beyermann, B.; Breu, V.; Löffler, B. M.; Schlotthauer, K.; Maier, L. S.   & Schmidt-Schweda, S. et al.​ (2012) 
    Circulation99(14) pp. 1802​-1809​.​ DOI: https://doi.org/10.1161/01.cir.99.14.1802 
    Details  DOI 
  • 2012 Journal Article | Overview | 
    ​ ​New Treatment Options for Late Na Current, Arrhythmias, and Diastolic Dysfunction​
    Maier, L. S. ​ (2012) 
    Current Heart Failure Reports9(3) pp. 183​-191​.​ DOI: https://doi.org/10.1007/s11897-012-0099-3 
    Details  DOI 
  • 2010 Journal Article | Research Paper
    ​ ​A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy​
    Knöll, R.; Kostin, S.; Klede, S.; Savvatis, K.; Klinge, L. ; Stehle, I. & Gunkel, S. et al.​ (2010) 
    Circulation Research106(4) pp. 695​-704​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.109.206243 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​Frequency-dependence of the slow force response​
    Lewinski, D. von; Zhu, D.; Khafaga, M.; Kockskamper, J.; Maier, L. S. ; Hasenfuss, G.   & Pieske, B. ​ (2008) 
    Frontiers in Bioscience13 pp. 7202​-7209​.​ DOI: https://doi.org/10.2741/3222 
    Details  DOI  PMID  PMC  WoS 
  • 1999 Journal Article
    ​ ​Relationship Between Na + -Ca 2+ –Exchanger Protein Levels and Diastolic Function of Failing Human Myocardium​
    Hasenfuß, G. ; Schillinger, W.; Lehnart, S. E. ; Preuss, M.; Pieske, B.; Maier, L. S.   & Prestle, J. et al.​ (1999) 
    Circulation99(5) pp. 641​-648​.​ DOI: https://doi.org/10.1161/01.CIR.99.5.641 
    Details  DOI 
  • 1998 Journal Article
    ​ ​Influence of SR Ca2+-ATPase and Na+-Ca2+-exchanger on the force-frequency relation​
    Schillinger, W. ; Lehnart, S. E. ; Prestle, J. ; Preuss, M.; Pieske, B. ; Maier, L. S.   & Meyer, M. et al.​ (1998) 
    Basic Research in Cardiology93(Supplement 1) pp. 38​-45​.​ DOI: https://doi.org/10.1007/s003950050208 
    Details  DOI 

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