EXC 2067: Multiscale Bioimaging RSS Feed


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  • 2024 | Journal Article
    ​ ​Structure of the multi-subunit chloroplast RNA polymerase​
    do Prado, P. F. V.; Ahrens, F. M.; Liebers, M.; Ditz, N.; Braun, H.-P.; Pfannschmidt, T. & Hillen, H. S.​ (2024) 
    Molecular Cell, 84(5) pp. 910​-925.e5​.​ DOI: https://doi.org/10.1016/j.molcel.2024.02.003 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis​
    Galbusera, R.; Bahn, E.; Weigel, M.; Cagol, A.; Lu, P.-J.; Schaedelin, S. A. & Franz, J. et al.​ (2024) 
    Neurology, 102(3) art. e207966​.​ DOI: https://doi.org/10.1212/WNL.0000000000207966 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid​
    Aubrey, L. D.; Ninkina, N.; Ulamec, S. M.; Abramycheva, N. Y.; Vasili, E.; Devine, O. M. & Wilkinson, M. et al.​ (2024) 
    Proceedings of the National Academy of Sciences of the United States of America, 121(2) art. e2309700120​.​ DOI: https://doi.org/10.1073/pnas.2309700120 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Uncovering potential diagnostic and pathophysiological roles of α-synuclein and DJ-1 in melanoma​
    Quesnel, A.; Martin, L. D.; Tarzi, C.; Lenis, V. P.; Coles, N.; Islam, M. & Angione, C. et al.​ (2024) 
    Cancer Medicine,.​ DOI: https://doi.org/10.1002/cam4.6900 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM​
    Rapöhn, M.; Cyganek, L.; Voigt, N.; Hasenfuß, G.; Lehnart, S. E & Wegener, J. W​ (2024) 
    American Journal of Physiology. Heart and Circulatory Physiology,.​ DOI: https://doi.org/10.1152/ajpheart.00527.2023 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Image restoration of degraded time-lapse microscopy data mediated by near-infrared imaging​
    Gritti, N.; Power, R. M.; Graves, A. & Huisken, J.​ (2024) 
    Nature Methods,.​ DOI: https://doi.org/10.1038/s41592-023-02127-z 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes​
    Paasche, A.; Wiedmann, F.; Kraft, M.; Seibertz, F.; Herlt, V.; Blochberger, P. L. & Jávorszky, N. et al.​ (2024) 
    Basic Research in Cardiology,.​ DOI: https://doi.org/10.1007/s00395-023-01022-0 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Local Water Content in Polymer Gels Measured With Super-Resolved Fluorescence Lifetime Imaging​
    Jana, S.; Nevskyi, O.; Höche, H.; Trottenberg, L.; Siemes, E.; Enderlein, J. & Fürstenberg, A. et al.​ (2024) 
    Angewandte Chemie. International Edition, art. e202318421​.​ DOI: https://doi.org/10.1002/anie.202318421 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins​
    Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A. A.; Fedou, S.; Thézé, N.; Zabelskii, D. & Alekseev, A. et al.​ (2024) 
    Nature Communications, 15(1) pp. 65​.​ DOI: https://doi.org/10.1038/s41467-023-44548-6 
    ​Details  DOI  PMID  PMC 
  • 2024 | Preprint
    ​ ​Rational Approximation of Golden Angles for Simple and Reproducible Radial Sampling​
    Scholand, N.; Graf, C.; Mackner, D.; Holme, H. C. M.& Uecker, M.​ (2024). DOI: https://doi.org/10.48550/ARXIV.2401.02892 
    ​Details  DOI 
  • 2024 | Preprint
    ​ ​Thermogenetics for cardiac pacing​
    Balatskiy, A. V.; Nesterenko, A. M.; Lanin, A. A.; Ovechkina, V. S.; Sabinin, S. S.; Fetisova, E. S.& Moshchenko, A. A. et al.​ (2024). DOI: https://doi.org/10.1101/2024.01.02.573885 
    ​Details  DOI 
  • 2024 | Journal Article
    ​ ​Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus​
    Hintze, A.; Lange, F.; Steyer, A. M.; Anstatt, J.; Möbius, W.; Jakobs, S. & Wichmann, C.​ (2024) 
    iScience, 27(1) art. 108700​.​ DOI: https://doi.org/10.1016/j.isci.2023.108700 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria​
    Poerschke, S.; Oeljeklaus, S.; Cruz-Zaragoza, L. D.; Schenzielorz, A.; Dahal, D.; Hillen, H. S. & Das, H. et al.​ (2023) 
    Molecular Cell,.​ DOI: https://doi.org/10.1016/j.molcel.2023.12.013 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase​
    Sievers, K.; Neumann, P.; Sušac, L.; Da Vela, S.; Graewert, M.; Trowitzsch, S. & Svergun, D. et al.​ (2023) 
    Structure,.​ DOI: https://doi.org/10.1016/j.str.2023.12.006 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells​
    Schreiber, M.-K. & Zafeiriou, M.-P.​ (2023) 
    Stem Cell Research, 75 art. 103295​.​ DOI: https://doi.org/10.1016/j.scr.2023.103295 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis​
    Sant’Anna, R.; Robbs, B. K.; de Freitas, J. A.; dos Santos, P. P.; König, A.; Outeiro, T. F. & Foguel, D.​ (2023) 
    Molecular Medicine, 29(1) art. 111​.​ DOI: https://doi.org/10.1186/s10020-023-00704-8 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism​
    Grammatika Pavlidou, N.; Dobrev, S.; Beneke, K.; Reinhardt, F.; Pecha, S.; Jacquet, E. & Abu-Taha, I. H. et al.​ (2023) 
    European Heart Journal,.​ DOI: https://doi.org/10.1093/eurheartj/ehad086 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Trafficking proteins show limited differences in mobility across different postsynaptic spines​
    Mougios, N.; Opazo, F. ; Rizzoli, S. O.   & Reshetniak, S.​ (2023) 
    iScience, 26(2) art. 105971​.​ DOI: https://doi.org/10.1016/j.isci.2023.105971 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reaction​
    Fu, Y.; Simeth, N. A. ; Toyoda, R.; Brilmayer, R.; Szymanski, W. & Feringa, B. L.​ (2023) 
    Angewandte Chemie. International Edition, art. e202218203​.​ DOI: https://doi.org/10.1002/anie.202218203 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF​
    Antoniou, A.; Auderset, L.; Kaurani, L.; Sebastian, E.; Zeng, Y.; Allahham, M. & Cases-Cunillera, S. et al.​ (2023) 
    Cell Reports, 42(2) art. 112063​.​ DOI: https://doi.org/10.1016/j.celrep.2023.112063 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system​
    Saha, I.; Yuste-Checa, P.; Da Silva Padilha, M.; Guo, Q.; Körner, R.; Holthusen, H. & Trinkaus, V. A. et al.​ (2023) 
    Nature Communications, 14(1) pp. 560​.​ DOI: https://doi.org/10.1038/s41467-023-36058-2 
    ​Details  DOI  PMID  PMC 
  • 2023 | Preprint
    ​ ​In vitro reconstitution of chromatin domains​
    Quililan, K.; Oberbeckmann, E.; Cramer, P.& Oudelaar, A. M.​ (2023). DOI: https://doi.org/10.1101/2023.02.27.530214 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes​
    Haro-Moreno, J. M.; López-Pérez, M.; Alekseev, A.; Podoliak, E.; Kovalev, K.; Gordeliy, V.& Stepanauskas, R. et al.​ (2023). DOI: https://doi.org/10.1101/2023.01.04.522823 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome​
    Busley, A. V.; Gutiérrez-Gutiérrez, Ó.; Hammer, E.; Steinegger, M.; Böhmer, L.; Schroeder, H.& Kleinsorge, M. et al.​ (2023). DOI: https://doi.org/10.1101/2023.01.10.523203 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Age-dependent structural reorganization of utricular ribbon synapses​
    Michanski, S.; Henneck, T.; Mukhopadhyay, M.; Steyer, A. M.; Gonzalez, P. A.; Grewe, K.& Ilgen, P. et al.​ (2023). DOI: https://doi.org/10.1101/2022.12.19.521049 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse​
    Hain, P. J. H.& Moser, T. ​ (2023). DOI: https://doi.org/10.1101/2022.11.27.518035 
    ​Details  DOI 
  • 2023 | Journal Article | Overview
    ​ ​Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets​
    Mudryi, V.; Peske, F. & Rodnina, M. ​ (2023) 
    BBA Advances, 3 art. 100074​.​ DOI: https://doi.org/10.1016/j.bbadva.2023.100074 
    ​Details  DOI 
  • 2023 | Conference Paper
    ​ ​Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency​
    Schlotawa, L.; Matysiak, K.; Kettwig, M.; Ahrens-Nicklas, R. C.; Baud, M.; Berulava, T. & Brunetti-Pierri, N. et al.​ (2023)
    Neuropediatrics, 54(S01) pp. S1​-S32. ​German Neuropediatric Society Congress 2023​, Dortmund. DOI: https://doi.org/10.1055/s-0043-1777171 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Convergence of Empirical Optimal Transport in Unbounded Settings​
    Staudt, T.& Hundrieser, S.​ (2023). DOI: https://doi.org/10.48550/ARXIV.2306.11499 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Doubling the resolution of single-molecule localization microscopy with image scanning microscopy​
    Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.& Enderlein, J.​ (2023). DOI: https://doi.org/10.1101/2023.08.23.554438 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)​
    Frieg, B.; Han, M.; Giller, K.; Dienemann, C.; Riedel, D.; Becker, S.& Andreas, L. B. et al.​ (2023). DOI: https://doi.org/10.1101/2023.06.28.546947 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Multiscale scanning with nuisance parameters​
    König, C.; Munk, A.& Werner, F.​ (2023). DOI: https://doi.org/10.48550/ARXIV.2307.13301 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Infomorphic networks: Locally learning neural networks derived from partial information decomposition​
    Graetz, M.; Makkeh, A.; Schneider, A. C.; Ehrlich, D. A.; Priesemann, V.& Wibral, M.​ (2023). DOI: https://doi.org/10.48550/ARXIV.2306.02149 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Hijacking of internal calcium dynamics by intracellularly residing rhodopsins​
    Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A. A.; Fedou, S.; Thézé, N.; Zabelskii, D.& Alekseev, A. et al.​ (2023). DOI: https://doi.org/10.1101/2023.05.25.542240 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Unravelling ATP processing by the AAA+ protein p97 at the atomic level​
    Shein, M.; Hitzenberger, M.; Cheng, T. C.; Rout, S. R.; Leitl, K. D.; Sato, Y.& Zacharias, M. et al.​ (2023). DOI: https://doi.org/10.1101/2023.08.26.554927 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Metal-induced energy transfer (MIET) imaging of cell surface engineering with multivalent DNA nanobrushes​
    Wang, D.-X.; Liu, B.; Han, G.-M.; Li, Q.-N.; Kong, D.-M.; Enderlein, J.& Chen, T.​ (2023). DOI: https://doi.org/10.1101/2023.07.05.547790 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Measuring sub-nanometer fluctuations at microsecond temporal resolution with metal-and graphene-induced energy transfer spectroscopy​
    Chen, T.; Karedla, N.& Enderlein, J.​ (2023). DOI: https://doi.org/10.1101/2023.05.16.540910 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Segment Anything for Microscopy​
    Archit, A.; Nair, S.; Khalid, N.; Hilt, P.; Rajashekar, V.; Freitag, M.& Gupta, S. et al.​ (2023). DOI: https://doi.org/10.1101/2023.08.21.554208 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis​
    Ricagno, S.; Schulte, T.; Chaves-Sanjuan, A.; Speranzini, V.; Sicking, K.; Mazzini, G.& Rognoni, P. et al.​ (2023). DOI: https://doi.org/10.21203/rs.3.rs-3625869/v1 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Efficient and sustained optogenetic control of nervous and cardiac systems​
    Zerche, M.; Hunniford, V.; Alekseev, A.; May, F. E.; Vavakou, A.; Siegenthaler, D.& Hüser, M. A. et al.​ (2023). DOI: https://doi.org/10.1101/2023.11.17.567544 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Structure and dynamics of human cardiac fibroblast nanotubes​
    Schmid-Herbstritt, S. C.; Stief, G.; Greiner, J.; Felekary, A.; Madl, J.; Zeidler, V.& Heer, J. et al.​ (2023). DOI: https://doi.org/10.1101/2023.11.28.568871 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag​
    Kim, D.; Stoldt, S.; Weber, M.; Jakobs, S.; Belov, V. N. & Hell, S. W.​ (2023) 
    Chemistry Methods, 3(9).​ DOI: https://doi.org/10.1002/cmtd.202200076 
    ​Details  DOI 
  • 2023 | Conference Abstract
    ​ ​Approaching automation of multiple instance orchestration of the menoci web portal​
    Freckmann, L.; Henke, C.; Kossen, R.; Weber, L.; Suhr, M.; Sax, U. & Nussbeck, S. Y. et al.​ (2023)
    ​68. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)​, Heilbronn.
    German Medical Science GMS Publishing House. DOI: https://doi.org/10.3205/23GMDS020 
    ​Details  DOI 
  • 2023 | Conference Paper
    ​ ​In vitro and in vivo characterization of improved channelrhodopsin ChRmine variants for optogenetic activation of the auditory pathway​
    Zerche, M.; Hunniford, V.; Witzke, I.; Wolf, B.; Mager, T. & Moser, T.​ (2023)
    Laryngo-Rhino-Otologie, 102(S02) p. S287. ​94. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.​, Leipzig. DOI: https://doi.org/10.1055/s-0043-1767412 
    ​Details  DOI 
  • 2023 | Conference Paper
    ​ ​Characterization of novel channelrhodopsin variants for blue-light optogenetic activation of the auditory pathway​
    Roos, L.; Garrido-Charles, A.; Wolf, B.; Kusch, K.; Mager, T. & Moser, T.​ (2023)
    Laryngo-Rhino-Otologie, 102(S02) p. S279. ​94. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.​, Leipzig. DOI: https://doi.org/10.1055/s-0043-1767383 
    ​Details  DOI 
  • 2023 | Conference Paper
    ​ ​Investigating human lung tissue by propagation-based phase-contrast X-ray tomography​
    Reichmann, J.; Verleden, S.; Kühnel, M.; Kamp, J. C.; Werlein, C.; Neubert, L. & QuynhBui, T. et al.​ (2023)
    ​LEAPS Meets Life Sciences Conference, Bioimaging​, Elba.
    ​Details 
  • 2023 | Book Chapter
    ​ ​Fluorescence Spectroscopy in Planar Dielectric and Metallic Systems​
    Chizhik, A. I.; Ruhlandt, D.& Enderlein, J.​ (2023)
    In:​Benyoucef, Mohamed​ (Ed.), Photonic Quantum Technologies: Science and Applications pp. 151​-181. ​Wiley. DOI: https://doi.org/10.1002/9783527837427.ch8 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Bioengineering of a human innervated cardiac muscle model​
    Schneider, L. V.; Guobin, B.; Methi, A.; Jensen, O.; Schmoll, K. A.; Setya, M. G.& Sakib, S. et al.​ (2023). DOI: https://doi.org/10.1101/2023.08.18.552653 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​A metabolically controlled contact site between lipid droplets and vacuoles​
    Diep, D. T. V.; Collado, J. F.; Hugenroth, M.; Wälte, M.; Schmidt, O.; Fernández-Busnadiego, R.& Bohnert, M.​ (2023). DOI: https://doi.org/10.1101/2023.04.21.537652 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Approaching automation of multiple instance orchestration of the menoci web portal​
    Freckmann, L.; Henke, C.; Kossen, R.; Weber, L.; Sax, U.; Nussbeck, S. Y. & Kusch, H.​ (2023) 
    Bausteine Forschungsdatenmanagement, 5 pp. 1​-11​.​ DOI: https://doi.org/10.17192/BFDM.2023.5.8608 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Boosting of neural circuit chaos at the onset of collective oscillations​
    Palmigiano, A.; Engelken, R.& Wolf, F.​ (2023). DOI: https://doi.org/10.1101/2022.08.28.505598 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments​
    Stephan, T.; Stoldt, S.; Barbot, M.; Carney, T. D.; Lange, F.; Bates, M.& Dib, P. B. et al.​ (2023). DOI: https://doi.org/10.1101/2023.04.17.537183 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice​
    Edelman, B. J.; Siegenthaler, D.; Wanken, P.; Jenkins, B.; Schmid, B.; Ressle, A.& Gogolla, N. et al.​ (2023). DOI: https://doi.org/10.1101/2023.10.02.560470 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy​
    Kyriakopoulou, E.; Versteeg, D.; de Ruiter, H.; Perini, I.; Seibertz, F.; Döring, Y. & Zentilin, L. et al.​ (2023) 
    Nature cardiovascular research, 2(12) pp. 1262​-1276​.​ DOI: https://doi.org/10.1038/s44161-023-00378-9 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​Natural stimuli drive concerted nonlinear responses in populations of retinal ganglion cells​
    Karamanlis, D.; Khani, M. H.; Schreyer, H. M.; Zapp, S. J.; Mietsch, M.& Gollisch, T. ​ (2023). DOI: https://doi.org/10.1101/2023.01.10.523412 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Boosting of neural circuit chaos at the onset of collective oscillations​
    Palmigiano, A.; Engelken, R. & Wolf, F.​ (2023) 
    eLife,.​ DOI: https://doi.org/10.7554/eLife.90378 
    ​Details  DOI 
  • 2023 | Preprint
    ​ ​A scalable clustering algorithm to approximate graph cuts​
    Suchan, L.; Li, H.  & Munk, A. ​ (2023). DOI: https://doi.org/10.48550/ARXIV.2308.09613 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​MemBrain: A deep learning-aided pipeline for detection of membrane proteins in Cryo-electron tomograms​
    Lamm, L.; Righetto, R. D; Wietrzynski, W.; Pöge, M.; Martinez-Sanchez, A.; Peng, T. & Engel, B. D​ (2022) 
    Computer Methods and Programs in Biomedicine, 224 art. 106990​.​ DOI: https://doi.org/10.1016/j.cmpb.2022.106990 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative Analysis​
    Oleksiievets, N.; Mathew, C.; Thiele, J. C.; Gallea, J. I.; Nevskyi, O.; Gregor, I. & Weber, A. et al.​ (2022) 
    Nano Letters, 22(15) pp. 6454​-6461​.​ DOI: https://doi.org/10.1021/acs.nanolett.2c01586 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Overview | 
    ​ ​Is there an unmet medical need for improved hearing restoration?​
    Wolf, B. J.; Kusch, K. ; Hunniford, V.; Vona, B.; Kühler, R.; Keppeler, D.   & Strenzke, N.  et al.​ (2022) 
    EMBO Molecular Medicine, 14(8) art. e15798​.​ DOI: https://doi.org/10.15252/emmm.202215798 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues​
    Santos, G. L.; DeGrave, A. N.; Rehman, A.; Al Disi, S.; Xhaxho, K.; Schröder, H. & Bao, G. et al.​ (2022) 
    Biomaterials Advances, 139 art. 213041​.​ DOI: https://doi.org/10.1016/j.bioadv.2022.213041 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study​
    Lange, T.; Backhaus, S. J.; Beuthner, B. E.; Topci, R.; Rigorth, K.-R.; Kowallick, J. T. & Evertz, R. et al.​ (2022) 
    Journal of Cardiovascular Magnetic Resonance, 24(1) art. 45​.​ DOI: https://doi.org/10.1186/s12968-022-00874-0 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX​
    Grabner, C. P.; Jansen, I.; Neef, J.; Weihs, T.; Schmidt, R.; Riedel, D. & Wurm, C. A. et al.​ (2022) 
    Science Advances, 8(28) art. eabl7560​.​ DOI: https://doi.org/10.1126/sciadv.abl7560 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Structure of a backtracked hexasomal intermediate of nucleosome transcription​
    Farnung, L.; Ochmann, M.; Garg, G.; Vos, S. M. & Cramer, P. ​ (2022) 
    Molecular Cell,.​ DOI: https://doi.org/10.1016/j.molcel.2022.06.027 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Distinct roles of the meningeal layers in CNS autoimmunity​
    Merlini, A.; Haberl, M.; Strauß, J.; Hildebrand, L.; Genc, N.; Franz, J. & Chilov, D. et al.​ (2022) 
    Nature Neuroscience, 25(7) pp. 887​-899​.​ DOI: https://doi.org/10.1038/s41593-022-01108-3 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​A Mathematical Model for Electrical Activity in Pig Atrial Tissue​
    Peris-Yagüe, V.; Rubio, T.; Fakuade, F. E.; Voigt, N. ; Luther, S.   & Majumder, R.​ (2022) 
    Frontiers in Physiology, 13.​ DOI: https://doi.org/10.3389/fphys.2022.812535 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Overview | 
    ​ ​Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology​
    Chowdhury, A.; Witte, S. & Aich, A.​ (2022) 
    Frontiers in Cell and Developmental Biology, 10.​ DOI: https://doi.org/10.3389/fcell.2022.796066 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2 Interaction in Constrained Geometries​
    Dietz, J.; Oelkers, M.; Hubrich, R.; Pérez-Lara, A.; Jahn, R.; Steinem, C.   & Janshoff, A. ​ (2022) 
    Nano Letters, 22(3) pp. 1449​-1455​.​ DOI: https://doi.org/10.1021/acs.nanolett.1c02491 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures​
    Gönenc, I. I.; Wolff, A.; Schmidt, J.; Zibat, A.; Müller, C.; Cyganek, L. & Argyriou, L. et al.​ (2022) 
    Human Molecular Genetics,.​ DOI: https://doi.org/10.1093/hmg/ddab373 
    ​Details  DOI  PMID  PMC 
  • 2022 | Preprint
    ​ ​On the Uniqueness of Kantorovich Potentials​
    Staudt, T.; Hundrieser, S.& Munk, A. ​ (2022)
    ​Details  arXiv 
  • 2022 | Journal Article | Research Paper
    ​ ​Molecular and functional architecture of striatal dopamine release sites​
    Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L. & Wang, J. et al.​ (2022) 
    Neuron, 110(2) pp. 248.e9​-265.e9​.​ DOI: https://doi.org/10.1016/j.neuron.2021.10.028 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Erratum | 
    ​ ​Author Correction: Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms​
    Moebel, E.; Martinez-Sanchez, A.; Lamm, L.; Righetto, R. D.; Wietrzynski, W.; Albert, S. & Larivière, D. et al.​ (2022) 
    Nature Methods, 19(1) pp. 129​-129​.​ DOI: https://doi.org/10.1038/s41592-021-01349-3 
    ​Details  DOI  PMID  PMC 
  • 2022 | Preprint
    ​ ​Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II​
    Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.& Urlaub, H. et al.​ (2022). DOI: https://doi.org/10.1101/2022.09.21.508861 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Effects of cryo-EM cooling on structural ensembles​
    Bock, L. V.& Grubmüller, H. ​ (2022). DOI: https://doi.org/10.1101/2021.10.08.463658 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​The 3D structure of lipidic fibrils of α-synuclein​
    Frieg, B.; Antonschmidt, L.; Dienemann, C.; Geraets, J. A.; Najbauer, E. E.; Matthes, D.& de Groot, B. L.  et al.​ (2022). DOI: https://doi.org/10.1101/2022.03.02.481946 
    ​Details  DOI 
  • 2022 | Conference Paper
    ​ ​In vivo investigation of f-Chrimson variants for optogenetic hearing restoration​
    Wrobel, C.; Zerche, M.; Kusch, K.; Mager, T.   & Moser, T. ​ (2022)
    Laryngo-Rhino-Otologie, 101(S02) pp. S243​-S244.  DOI: https://doi.org/10.1055/s-0042-1746830 
    ​Details  DOI 
  • 2022 | Conference Paper
    ​ ​Identification and optimization of channelrhodopsin variants for optogenetic hearing restoration​
    Zerche, M.; Moser, T.   & Mager, T. ​ (2022)
    Laryngo-Rhino-Otologie, 101(S02) pp. S243​-S244.  DOI: https://doi.org/10.1055/s-0042-1746832 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper
    ​ ​Statistical Methods for Minimax Estimation in Linear Models with Unknown Design Over Finite Alphabets​
    Behr, M. & Munk, A. ​ (2022) 
    SIAM Journal on Mathematics of Data Science, 4(2) pp. 490​-513​.​ DOI: https://doi.org/10.1137/21M1398860 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Roadmap for Optical Tweezers​
    Volpe, G.; Maragò, O. M.; Rubinzstein-Dunlop, H.; Pesce, G.; Stilgoe, A. B.; Volpe, G.& Tkachenko, G. et al.​ (2022). DOI: https://doi.org/10.48550/ARXIV.2206.13789 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina​
    Nitsche, S.; Khani, M. H.; Karamanlis, D.; Erol, Y. C.; Zapp, S. J.; Mietsch, M.& Protti, D. A. et al.​ (2022). DOI: https://doi.org/10.1101/2022.08.12.503725 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Statistical analysis of random objects via metric measure Laplacians​
    Mordant, G.& Munk, A. ​ (2022). DOI: https://doi.org/10.48550/arXiv.2204.06493 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses​
    Chakrabarti, R.; Jaime Tobon, L. M.; Slitin, L.; Redondo-Canales, M.; Hoch, G.; Slashcheva, M.& Fritsch, E. et al.​ (2022). DOI: https://doi.org/10.1101/2022.05.10.491334 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control​
    Nadler, F.; Lavdovskaia, E.; Krempler, A.; Cruz-Zaragoza, L. D.; Dennerlein, S.& Richter-Dennerlein, R. ​ (2022). DOI: https://doi.org/10.1101/2022.07.08.499411 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​In silico modeling for personalized stenting in aortic coarctation​
    Ma, D.; Wang, Y.; Azhar, M.; Adler, A.; Steinmetz, M.& Uecker, M. ​ (2022). DOI: https://doi.org/10.48550/ARXIV.2205.04518 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data​
    Chen, X.; Sailer, C.; Kammer, K. M.; Fürsch, J.; Eisele, M. R.; Sakata, E.  & Stengel, F.​ (2022). DOI: https://doi.org/10.1101/2022.02.03.478943 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Graded optogenetic activation of the auditory pathway for hearing restoration​
    Mittring, A.; Moser, T.  & Huet, A. ​ (2022). DOI: https://doi.org/10.1101/2022.09.05.506618 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABAARs and cytosolic gephyrin aggregation​
    Zeppillo, T.; Ali, H.; Wenger, S.; Lopez Murcia, F. J.; Gideons, E.; Signorelli, J.& Schmeisser, M. J. et al.​ (2022). DOI: https://doi.org/10.1101/2022.08.08.503083 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling​
    Paulke, N.; Amlaz, S.; Fleischhacker, C.; Kohl, T.; Kownatzki-Danger, D.; Hasenfuss, G.   & Lehnart, S.  et al.​ (2022) 
    European Heart Journal, 43(Suppl. 2).​ DOI: https://doi.org/10.1093/eurheartj/ehac544.2944 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Graphene-Induced Energy Transfer for Quantitative Membrane Biophysics at Sub-Nanometer Resolution​
    Chen, T.; Ghosh, A.& Enderlein, J. ​ (2022). DOI: https://doi.org/10.48550/ARXIV.2211.03517 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita​
    Schnabel, F.; Schuler, E.; Al-Maawali, A.; Chaurasia, A.; Syrbe, S.; Al-Kindi, A.& Bhav, G. S. et al.​ (2022). DOI: https://doi.org/10.21203/rs.3.rs-2121654/v1 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Unbalanced Kantorovich-Rubinstein distance and barycenter for finitely supported measures: A statistical perspective​
    Heinemann, F.; Klatt, M.& Munk, A. ​ (2022). DOI: https://doi.org/10.48550/ARXIV.2211.08858 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses​
    Michanski, S.; Kapoor, R.; Steyer, A. M.; Möbius, W. ; Früholz, I.; Ackermann, F.& Gültas, M. et al.​ (2022). DOI: https://doi.org/10.1101/2022.12.15.520589 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Dystrophin is a mechanical tension modulator​
    Hofemeier, A. D.; Muenker, T. M.; Herkenrath, F.; Ristau, M.; Brandt, M.; Shahriyari, M.& Tiburcy, M. et al.​ (2022). DOI: https://doi.org/10.1101/2022.12.23.521750 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress​
    Nanadikar, M.; Leon, A. V.; Guo, J.; Belle, G. van; Jatho, A.; Brandner, A.& Böckmann, R. et al.​ (2022). DOI: https://doi.org/10.21203/rs.3.rs-1594117/v1 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain​
    Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Romanowski, A. J.& Robertson, C. D. et al.​ (2022). DOI: https://doi.org/10.1101/2022.07.23.501257 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Whole genome sequencing for newborns—The devil is in the details​
    Vona, B.​ (2022) 
    Clinical and Translational Discovery, 2(3).​ DOI: https://doi.org/10.1002/ctd2.102 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Cryo-electron tomography reveals enrichment and identifies microtubule lumenal particles in neuronal differentiation​
    Chakraborty, S.; Martinez-Sanchez, A.; Beck, F.; Toro-Nahuelpan, M.; Hwang, I.-Y.; Noh, K.-M.& Baumeister, W. et al.​ (2022). DOI: https://doi.org/10.1101/2022.07.28.501854 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​From LUVs to GUVs - how to cover micrometer-sized pores with membranes​
    Kramer, K.; Sari, M.; Schulze, K.; Flegel, H.; Stehr, M.; Mey, I.& Janshoff, A.  et al.​ (2022). DOI: https://doi.org/10.26434/chemrxiv-2022-1jtms 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli​
    Shahidi, N.; Rozenblit, F.; Khani, M. H.; Schreyer, H. M.; Mietsch, M.; Protti, D. A.& Gollisch, T. ​ (2022). DOI: https://doi.org/10.1101/2022.12.01.518577 
    ​Details  DOI 
  • 2022 | Journal Article | Discussion
    ​ ​New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain​
    Weninger, G. & Lehnart, S. E. ​ (2022) 
    Journal of Cellular Signaling, 3(4).​ DOI: https://doi.org/10.33696/Signaling.3.081 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Impact of native-like lipid membranes on the architecture and contractility of actomyosin networks​
    Liebe, N. L.; Mey, I.; Vuong, L.; Geil, B.; Janshoff, A.  & Steinem, C. ​ (2022). DOI: https://doi.org/10.1101/2022.07.22.501094 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Expansion microscopy at one nanometer resolution​
    Shaib, A. H.; Chouaib, A. A.; Imani, V.; Chowdhury, R.; Georgiev, S. V.; Mougios, N.& Monga, M. et al.​ (2022). DOI: https://doi.org/10.1101/2022.08.03.502284 
    ​Details  DOI 
  • 2022 | Journal Article | Overview | 
    ​ ​Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden​
    Bhatta, A. & Hillen, H. S. ​ (2022) 
    Biospektrum, 28(1) pp. 18​-20​.​ DOI: https://doi.org/10.1007/s12268-022-1711-z 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance​
    Ding, Y.; Korchak, S.; Mamone, S.; Jagtap, A. P.; Stevanato, G.; Sternkopf, S. & Moll, D. et al.​ (2022) 
    Chemistry Methods, 2(7).​ DOI: https://doi.org/10.1002/cmtd.202200023 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming​
    Lyra-Leite, D. M.; Gutiérrez-Gutiérrez, Ó.; Wang, M.; Zhou, Y.; Cyganek, L.   & Burridge, P. W.​ (2022) 
    STAR Protocols, 3(3) art. 101560​.​ DOI: https://doi.org/10.1016/j.xpro.2022.101560 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration​
    Liu, J. K. ; Karamanlis, D.& Gollisch, T. ​ (2022). DOI: https://doi.org/10.1101/2021.08.29.458067 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​A quantitative fluorescence-based approach to study mitochondrial protein import​
    Jain, N.; Gomkale, R.; Bernhard, O.; Rehling, P.  & Cruz-Zaragoza, L. D.​ (2022). DOI: https://doi.org/10.1101/2022.10.10.511594 
    ​Details  DOI 
  • 2022 | Preprint
    ​ ​The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity​
    Stewart, H.; Lu, Y.; O’Keefe, S.; Valpadashi, A.; Cruz-Zaragoza, L. D.; Michel, H. A.& Nguyen, S. K. et al.​ (2022). DOI: https://doi.org/10.1101/2022.11.15.516323 
    ​Details  DOI 
  • 2022 | Journal Article | Overview
    ​ ​The Role of Junctophilin Proteins in Cellular Function​
    Lehnart, S. E.   & Wehrens, X. H. T.​ (2022) 
    Physiological Reviews,.​ DOI: https://doi.org/10.1152/physrev.00024.2021 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants​
    Khurana, L.; Keppeler, D.; Jablonski, L. & Moser, T. ​ (2022) 
    Computational and structural biotechnology journal, 20 pp. 3621​-3629​.​ DOI: https://doi.org/10.1016/j.csbj.2022.06.061 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper
    ​ ​Mechanism of spindle pole organization and instability in human oocytes​
    So, C.; Menelaou, K.; Uraji, J.; Harasimov, K.; Steyer, A. M.; Seres, K. B. & Bucevičius, J. et al.​ (2022) 
    Science, 375(6581) art. eabj3944​.​ DOI: https://doi.org/10.1126/science.abj3944 
    ​Details  DOI  PMID  PMC 
  • 2021 | Preprint
    ​ ​Minimax detection of localized signals in statistical inverse problems​
    Pohlmann, M.; Werner, F.& Munk, A. ​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms​
    Heinemann, F.; Klatt, M.& Munk, A. ​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​Free-Breathing Myocardial T1 Mapping using Inversion-Recovery Radial FLASH and Motion-Resolved Model-Based Reconstruction​
    Wang, X.; Rosenzweig, S.; Roeloffs, V.; Blumenthal, M.; Tan, Z.; Scholand, N.& Holme, H. C. M. et al.​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​Optimal transfer functions for bandwidth-limited imaging​
    Stallinga, S.; Delon, A.& Enderlein, J. ​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​Statistical spatial analysis for cryo-electron tomography​
    Martinez-Sanchez, A.; Baumeister, W.& Lučić, V.​ (2021)
    ​Details  arXiv 
  • 2021 | Journal Article | Overview
    ​ ​Physics-based reconstruction methods for magnetic resonance imaging​
    Wang, X.; Tan, Z.; Scholand, N.; Roeloffs, V. & Uecker, M. ​ (2021) 
    Philosophical Transactions of the Royal Society of London. A, Mathematical, Physical and Engineering Sciences, 379(2200) art. 20200196​.​ DOI: https://doi.org/10.1098/rsta.2020.0196 
    ​Details  DOI  PMID  PMC 
  • 2021 | Preprint
    ​ ​Limit Distributions and Sensitivity Analysis for Entropic Optimal Transport on Countable Spaces​
    Hundrieser, S.; Klatt, M.& Munk, A. ​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​The Statistics of Circular Optimal Transport​
    Hundrieser, S.; Klatt, M.& Munk, A. ​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​The ultrametric Gromov-Wasserstein distance​
    Mémoli, F.; Munk, A. ; Wan, Z.& Weitkamp, C.​ (2021)
    ​Details  arXiv 
  • 2021 | Preprint
    ​ ​Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures​
    Gönenc, I. I.; Wolff, A.; Schmidt, J.; Zibat, A.; Müller, C.; Cyganek, L.  & Argyriou, L. et al.​ (2021). DOI: https://doi.org/10.1101/2021.10.01.462717 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis​
    Kabinger, F.; Stiller, C.; Schmitzová, J.; Dienemann, C.; Hillen, H. S. ; Höbartner, C.& Cramer, P. ​ (2021). DOI: https://doi.org/10.1101/2021.05.11.443555 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Sequence determinants of human gene regulatory elements​
    Sahu, B.; Hartonen, T.; Pihlajamaa, P.; Wei, B.; Dave, K.; Zhu, F.& Kaasinen, E. et al.​ (2021). DOI: https://doi.org/10.1101/2021.03.18.435942 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging​
    Raja, S. O.; Chizhik, A. I.; Schmidt, C. F.; Enderlein, J.  & Ghosh, A.​ (2021). DOI: https://doi.org/10.1101/2021.06.15.448547 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways​
    Schaffner, S. L.; Wassouf, Z.; Lazaro, D. F.; Xylaki, M.; Gladish, N.; Lin, D. T. S.& MacIsaac, J. et al.​ (2021). DOI: https://doi.org/10.1101/2021.06.12.448150 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy​
    Oliveira da Silva, M. I.; Santejo, M.; Babcock, I. W.; Magalhães, A.; Minamide, L. S.; Castillo, E.& Gerhardt, E. et al.​ (2021). DOI: https://doi.org/10.1101/2021.02.02.425931 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells​
    Vasili, E.; Dominguez-Meijide, A.; Flores-Léon, M.; Al-Azzani, M.; Kanellidi, A.; Melki, R.& Stefanis, L. et al.​ (2021). DOI: https://doi.org/10.21203/rs.3.rs-1152192/v1 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Oct4 primarily controls enhancer activity rather than accessibility​
    Xiong, L.; Tolen, E. A.; Choi, J.; Caizzi, L.; Adachi, K.; Lidschreiber, M.& Cramer, P.  et al.​ (2021). DOI: https://doi.org/10.1101/2021.06.28.450119 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons​
    Riemenschneider, H.; Guo, Q.; Bader, J.; Frottin, F.; Farny, D.; Kleinberger, G.& Haass, C. et al.​ (2021). DOI: https://doi.org/10.1101/2021.03.15.435268 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​A DNA-based optical force sensor for live-cell applications​
    Jayachandran, C.; Ghosh, A.; Prabhune, M.; Bath, J.; Turberfield, A. J.; Hauke, L.& Enderlein, J. et al.​ (2021). DOI: https://doi.org/10.1101/2021.12.21.473677 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity​
    Riera-Tur, I.; Schäfer, T.; Hornburg, D.; Mishra, A.; Fernández-Mosquera, L.; Feigenbutz, D.& Auer, P. et al.​ (2021). DOI: https://doi.org/10.1101/2019.12.16.877431 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel​
    Kolář, M. H.; Nagy, G.; Kunkel, J.; Vaiana, S. M.; Bock, L. V.& Grubmüller, H. ​ (2021). DOI: https://doi.org/10.1101/2021.04.15.440051 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain​
    Weish, P.; Lázaro, D. F.; Palmares, L.; Santos, P. I.; Stadelmann, C. ; Höglinger, G. U.& Rizzoli, S. O.  et al.​ (2021). DOI: https://doi.org/10.1101/2021.04.25.441304 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Dimeric form of SARS-CoV-2 polymerase​
    Jochheim, F. A.; Tegunov, D.; Hillen, H. S. ; Schmitzova, J.; Kokic, G.; Dienemann, C.& Cramer, P. ​ (2021). DOI: https://doi.org/10.1101/2021.03.23.436644 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease​
    Shomroni, O.; Sitte, M.; Schmidt, J.; Parbin, S.; Ludewig, F.; Yigit, G.& Zelarayan, L. C.  et al.​ (2021). DOI: https://doi.org/10.21203/rs.3.rs-957427/v1 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Cryo-electron tomography of native Drosophila tissues vitrified by plunge freezing​
    Bäuerlein, F. J. B.; Pastor-Pareja, J. C.& Fernández Busnadiego, R. ​ (2021). DOI: https://doi.org/10.1101/2021.04.14.437159 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Instant three color multi-plane fluorescence microscopy​
    Gregor, I.; Butkevich, E.; Enderlein, J.  & Mojiri, S.​ (2021). DOI: https://doi.org/10.1101/2021.05.07.443091 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​PolyQ expansion does not alter the Huntingtin-HAP40 complex​
    Huang, B.; Guo, Q.; Niedermeier, M. L.; Cheng, J.; Engler, T.; Maurer, M.& Pautsch, A. et al.​ (2021). DOI: https://doi.org/10.1101/2021.02.02.429316 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea​
    Garrido-Charles, A.; Huet, A.; Matera, C.; Thirumalai, A.; Llebaria, A.; Moser, T.  & Gorostiza, P.​ (2021). DOI: https://doi.org/10.1101/2021.05.25.445123 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites​
    Elizarova, S.; Chouaib, A.; Shaib, A.; Mann, F.; Brose, N. ; Kruss, S.& Daniel, J. A.​ (2021). DOI: https://doi.org/10.1101/2021.03.28.437019 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation​
    Torres-Garcia, L.; Domingues, J. M.; Brandi, E.; Haikal, C.; Brás, I. C.; Gerhardt, E.& Li, W. et al.​ (2021). DOI: https://doi.org/10.21203/rs.3.rs-960446/v1 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Ectosomes and exosomes are distinct proteomic entities that modulate spontaneous activity in neuronal cells​
    Brás, I. C.; Khani, M. H.; Riedel, D.; Parfentev, I.; Gerhardt, E.; van Riesen, C.& Urlaub, H. et al.​ (2021). DOI: https://doi.org/10.1101/2021.06.24.449731 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Allosteric control of Ubp6 and the proteasome via a bidirectional switch​
    Hung, K. Y. S.; Klumpe, S.; Eisele, M. R.; Elsasser, S.; Tian, G.; Sun, S.& Moroco, J. A. et al.​ (2021). DOI: https://doi.org/10.1101/2021.07.16.452743 
    ​Details  DOI 
  • 2021 | Conference Abstract
    ​ ​Free-Breathing Liver Fat and R2 Mapping: Multi-Echo Radial FLASH and Model-based Reconstruction (MERLOT)​
    Tan, Z.; Rosenzweig, S.; Wang, X.; Scholand, N.; Holme, H. C. M.; Blumenthal, M. & Uecker, M. ​ (2021)
    ​Proceedings. ​2021 ISMRM & SMRT Annual Meeting & Exhibition​
    ​Details 
  • 2021 | Preprint
    ​ ​Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity​
    Shahriyari, M.; Islam, M. R.; Sakib, M. S.; Rika, A.; Krüger, D.; Kaurani, L.& Anandakumar, H. et al.​ (2021). DOI: https://doi.org/10.1101/2021.07.12.452030 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​A mathematical model for electrical activity in pig atrial tissue​
    Peris-Yagüe, V.; Rubio, T.; Fakuade, F. E.; Voigt, N. ; Luther, S.  & Majumder, R.​ (2021). DOI: https://doi.org/10.1101/2021.10.18.464761 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy​
    Grabner, C. P.; Jansen, I.; Neef, J.; Weiss, T.; Schmidt, R.; Riedel, D.& Wurm, C. A. et al.​ (2021). DOI: https://doi.org/10.1101/2021.05.28.446138 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells​
    Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W. ; Riedel, D.; Parfentev, I.& Gerhardt, E. et al.​ (2021). DOI: https://doi.org/10.1101/2021.07.18.452825 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers​
    Yudovich, S.; Marzouqe, A.; Kantorovitsch, J.; Teblum, E.; Chen, T.; Enderlein, J.  & Miller, E. W. et al.​ (2021). DOI: https://doi.org/10.1101/2021.12.10.472087 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies​
    Koss, D. J.; Erskine, D.; Porter, A.; Palmoski, P.; Leite, M.; Attems, J.& Outeiro, T. F. ​ (2021). DOI: https://doi.org/10.1101/2021.10.20.465125 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter​
    Katsenelson, M.; Shapira, I.; Abbas, E.; Styr, B.; Aïd, S.; Holzenberger, M.& Rizzoli, S.  et al.​ (2021). DOI: https://doi.org/10.1101/2021.12.11.469196 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus​
    Akol, I.; Heidrich, S.; ÓhAilín, D.; Hacker, C.; Villarreal, A.; Rauleac, T.& Bella, C. et al.​ (2021). DOI: https://doi.org/10.1101/2021.10.25.465562 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture revealed by STED nanoscopy​
    Wegner, W.; Steffens, H.; Gregor, C.; Wolf, F.  & Willig, K. I. ​ (2021). DOI: https://doi.org/10.1101/2020.10.23.352195 
    ​Details  DOI 
  • 2021 | Preprint
    ​ ​Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling​
    Hillen, H. S. ; Lavdovskaia, E.; Nadler, F.; Hanitsch, E.; Linden, A.; Bohnsack, K. E.& Urlaub, H. et al.​ (2021). DOI: https://doi.org/10.1101/2021.03.17.435767 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Parental genome unification is highly error-prone in mammalian embryos​
    Cavazza, T.; Takeda, Y.; Politi, A. Z.; Aushev, M.; Aldag, P.; Baker, C. & Choudhary, M. et al.​ (2021) 
    Cell, 184(11) pp. 2860.e22​-2877.e22​.​ DOI: https://doi.org/10.1016/j.cell.2021.04.013 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo​
    Žumer, K.; Maier, K. C.; Farnung, L.; Jaeger, M. G.; Rus, P.; Winter, G. & Cramer, P. ​ (2021) 
    Molecular Cell, 81(15) pp. 3096.e8​-3109.e8​.​ DOI: https://doi.org/10.1016/j.molcel.2021.05.028 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening​
    Schilbach, S.; Aibara, S.; Dienemann, C.; Grabbe, F. & Cramer, P. ​ (2021) 
    Cell, 184(15) pp. 4064.e28​-4072.e28​.​ DOI: https://doi.org/10.1016/j.cell.2021.05.012 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy​
    Bertero, E.; Nickel, A.; Kohlhaas, M.; Hohl, M.; Sequeira, V.; Brune, C. & Schwemmlein, J. et al.​ (2021) 
    Circulation, 144(21) pp. 1694​-1713​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.121.053755 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells​
    Tegunov, D.; Xue, L.; Dienemann, C.; Cramer, P.   & Mahamid, J.​ (2021) 
    Nature Methods, 18(2) pp. 186​-193​.​ DOI: https://doi.org/10.1038/s41592-020-01054-7 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Allosteric transcription stimulation by RNA polymerase II super elongation complex​
    Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H. & Cramer, P. ​ (2021) 
    Molecular Cell, 81(16) pp. 3386.e10​-3399.e10​.​ DOI: https://doi.org/10.1016/j.molcel.2021.06.019 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Structure of a transcribing RNA polymerase II-U1 snRNP complex​
    Zhang, S.; Aibara, S.; Vos, S. M.; Agafonov, D. E.; Lührmann, R. & Cramer, P. ​ (2021) 
    Science, 371(6526) pp. 305​-309​.​ DOI: https://doi.org/10.1126/science.abf1870 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Structures and implications of TBP-nucleosome complexes​
    Wang, H.; Xiong, L. & Cramer, P. ​ (2021) 
    Proceedings of the National Academy of Sciences of the United States of America, 118(30) pp. e2108859118​.​ DOI: https://doi.org/10.1073/pnas.2108859118 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Integrator is a genome-wide attenuator of non-productive transcription​
    Lykke-Andersen, S.; Žumer, K.; Molska, E. Š.; Rouvière, J. O.; Wu, G.; Demel, C. & Schwalb, B. et al.​ (2021) 
    Molecular Cell, 81(3) pp. 514.e6​-529.e6​.​ DOI: https://doi.org/10.1016/j.molcel.2020.12.014 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Two mechanisms drive pronuclear migration in mouse zygotes​
    Scheffler, K.; Uraji, J.; Jentoft, I.; Cavazza, T.; Mönnich, E.; Mogessie, B. & Schuh, M. ​ (2021) 
    Nature Communications, 12(1) pp. 841​.​ DOI: https://doi.org/10.1038/s41467-021-21020-x 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Transcription activation depends on the length of the RNA polymerase II C-terminal domain​
    Sawicka, A.; Villamil, G.; Lidschreiber, M.; Darzacq, X.; Dugast-Darzacq, C.; Schwalb, B. & Cramer, P. ​ (2021) 
    The EMBO Journal, 40(9) art. e107015​.​ DOI: https://doi.org/10.15252/embj.2020107015 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Structures of mammalian RNA polymerase II pre-initiation complexes​
    Aibara, S.; Schilbach, S. & Cramer, P. ​ (2021) 
    Nature, 594(7861) pp. 124​-128​.​ DOI: https://doi.org/10.1038/s41586-021-03554-8 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Efficient RNA polymerase II pause release requires U2 snRNP function​
    Caizzi, L.; Monteiro-Martins, S.; Schwalb, B.; Lysakovskaia, K.; Schmitzova, J.; Sawicka, A. & Chen, Y. et al.​ (2021) 
    Molecular Cell, 81(9) pp. 1920.e9​-1934.e9​.​ DOI: https://doi.org/10.1016/j.molcel.2021.02.016 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Structure of the human Mediator-RNA polymerase II pre-initiation complex​
    Rengachari, S.; Schilbach, S.; Aibara, S.; Dienemann, C. & Cramer, P. ​ (2021) 
    Nature, 594(7861) pp. 129​-133​.​ DOI: https://doi.org/10.1038/s41586-021-03555-7 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Overview | 
    ​ ​Phase Separation during Germline Development​
    So, C.; Cheng, S. & Schuh, M. ​ (2021) 
    Trends in Cell Biology, 31(4) pp. 254​-268​.​ DOI: https://doi.org/10.1016/j.tcb.2020.12.004 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse​
    Butola, T.; Alvanos, T.; Hintze, A.; Koppensteiner, P.; Kleindienst, D.; Shigemoto, R. & Wichmann, C.  et al.​ (2021) 
    The Journal of Neuroscience, 41(37) pp. 7742​-7767​.​ DOI: https://doi.org/10.1523/JNEUROSCI.0586-21.2021 
    ​Details  DOI  PMID  PMC 
  • 2020 | Preprint
    ​ ​Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees​
    Heinemann, F.; Munk, A.  & Zemel, Y.​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Variational Multiscale Nonparametric Regression: Algorithms and Implementation​
    del Alamo, M.; Li, H. ; Munk, A.  & Werner, F.​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries​
    Kovács, S.; Li, H. ; Haubner, L.; Munk, A.  & Bühlmann, P.​ (2020)
    ​Details  arXiv 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases​
    Menezes, R.; Foito, A.; Jardim, C.; Costa, I.; Garcia, G.; Rosado-Ramos, R. & Freitag, S. et al.​ (2020) 
    Antioxidants, 9(9) pp. 789​.​ DOI: https://doi.org/10.3390/antiox9090789 
    ​Details  DOI  PMID  PMC 
  • 2020 | Preprint
    ​ ​CG-SENSE revisited: Results from the first ISMRM reproducibility challenge​
    Maier, O.; Baete, S. H.; Fyrdahl, A.; Hammernik, K.; Harrevelt, S.; Kasper, L.& Karakuzu, A. et al.​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Heterogeneous Idealization of Ion Channel Recordings -- Open Channel Noise​
    Pein, F.; Bartsch, A.; Steinem, C.  & Munk, A. ​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Gromov-Wasserstein Distance based Object Matching: Asymptotic Inference​
    Weitkamp, C. A.; Proksch, K.; Tameling, C.& Munk, A. ​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​What is resolution? A statistical minimax testing perspective on super-resolution microscopy​
    Kulaitis, G.; Munk, A.  & Werner, F.​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Seeded Binary Segmentation: A general methodology for fast and optimal change point detection​
    Kovács, S.; Li, H. ; Bühlmann, P.& Munk, A. ​ (2020)
    ​Details  arXiv 
  • 2020 | Preprint
    ​ ​Testing for dependence on tree structures​
    Behr, M.; Ansari, M. A.; Munk, A.  & Holmes, C.​ (2020). DOI: https://doi.org/10.1101/622811 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Structural basis of nucleosome transcription mediated by Chd1 and FACT​
    Farnung, L.; Ochmann, M.; Engeholm, M.& Cramer, P. ​ (2020). DOI: https://doi.org/10.1101/2020.11.30.403857 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Stable but not rigid: Long-term in vivo STED nanoscopy uncovers extensive remodeling of stable spines and indicates multiple drivers of structural plasticity​
    Steffens, H.; Mott, A. C.; Li, S.; Wegner, W.; Švehla, P.; Kan, V. W. Y.& Wolf, F.  et al.​ (2020). DOI: https://doi.org/10.1101/2020.09.21.306902 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Three-dimensional beating dynamics of Chlamydomonas flagella​
    Mojiri, S.; Isbaner, S.; Mühle, S.; Jang, H.; Bae, A. J.; Gregor, I.& Gholami, A. et al.​ (2020). DOI: https://doi.org/10.1101/2020.07.20.212159 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes​
    Michurina, A.; Sakib, S.; Kerimoglu, C.; Krüger, D. M.; Kaurani, L.; Islam, R.& Centeno, T. P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.07.240853 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Molecular and functional architecture of striatal dopamine release sites​
    Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L.& Wang, J. et al.​ (2020). DOI: https://doi.org/10.1101/2020.11.25.398255 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo​
    Dominguez-Meijide, A.; Parrales, V.; Vasili, E.; González-Lizárraga, F.; König, A.; Lázaro, D. F.& Lannuzel, A. et al.​ (2020). DOI: https://doi.org/10.1101/2020.11.06.371229 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.7 Å inside cells​
    Tegunov, D.; Xue, L.; Dienemann, C.; Cramer, P.  & Mahamid, J.​ (2020). DOI: https://doi.org/10.1101/2020.06.05.136341 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity​
    Medina, L.; González-Lizárraga, F.; Dominguez-Meijide, A.; Ploper, D.; Parrales, V.; Sequeira, S.& Cima-Omori, M. S. et al.​ (2020). DOI: https://doi.org/10.1101/2020.11.18.388561 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Choice of fluorophore affects dynamic DNA nanostructures​
    Jahnke, K.; Grubmüller, H. ; Igaev, M.& Göpfrich, K.​ (2020). DOI: https://doi.org/10.1101/2020.12.12.422444 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​White matter integrity requires continuous myelin synthesis at the inner tongue​
    Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K.; Jahn, O.; Piepkorn, L.& Agüi-Gonzalez, P. et al.​ (2020). DOI: https://doi.org/10.1101/2020.09.02.279612 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Local translation in synaptic mitochondria influences synaptic transmission​
    Yousefi, R.; Fornasiero, E. F.; Cyganek, L.; Jakobs, S. ; Rizzoli, S. O. ; Rehling, P.  & Pacheu-Grau, D.​ (2020). DOI: https://doi.org/10.1101/2020.07.22.215194 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​In situ architecture of neuronal α-Synuclein inclusions​
    Trinkaus, V. A.; Riera-Tur, I.; Martínez-Sánchez, A.; Bäuerlein, F. J. B.; Guo, Q.; Arzberger, T.& Baumeister, W. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.07.234138 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Multiple Haplotype Reconstruction from Allele Frequency Data​
    Pelizzola, M.; Behr, M.; Li, H. ; Munk, A.  & Futschik, A.​ (2020). DOI: https://doi.org/10.1101/2020.07.09.191924 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Parental genome unification is highly erroneous in mammalian embryos​
    Cavazza, T.; Politi, A. Z.; Aldag, P.; Baker, C.; Elder, K.; Blayney, M.& Lucas-Hahn, A. et al.​ (2020). DOI: https://doi.org/10.1101/2020.08.27.269779 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding​
    Bartsch, A.; Ives, C. M.; Kattner, C.; Pein, F.; Diehn, M.; Tanabe, M.& Munk, A.  et al.​ (2020). DOI: https://doi.org/10.1101/2020.11.06.369579 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders​
    Morato Torres, C. A.; Wassouf, Z.; Zafar, F.; Sastre, D.; Outeiro, T. F.  & Schüle, B.​ (2020). DOI: https://doi.org/10.20944/preprints202007.0334.v1 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Macromolecular and electrical coupling between inner hair cells in the rodent cochlea​
    Jean, P.; Anttonen, T.; Michanski, S.; de Diego, A. M. G.; Steyer, A. M.; Neef, A.& Oestreicher, D. et al.​ (2020). DOI: https://doi.org/10.1101/2019.12.17.879767 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19​
    Islam, M. R.& Fischer, A. ​ (2020). DOI: https://doi.org/10.20944/preprints202004.0399.v1 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Epigenetic gene-expression links heart failure to memory impairment​
    Islam, R.; Lbik, D.; Sakib, S.; Hofmann, R. M.; Berulava, T.; Mausbach, M. J.& Cha, J. et al.​ (2020). DOI: https://doi.org/10.1101/2020.01.22.915637 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R​
    Dankovich, T. M.; Kaushik, R.; Petersen, G. C.; Giro, P. E.; Hadi, H. A.; Bao, G.& Beuermann, S. et al.​ (2020). DOI: https://doi.org/10.1101/2020.11.11.377515 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Seeded intervals and noise level estimation in change point detection: a discussion of Fryzlewicz (2020)​
    Kovács, S.; Li, H.   & Bühlmann, P.​ (2020) 
    Journal of the Korean Statistical Society, 49(4) pp. 1081​-1089​.​ DOI: https://doi.org/10.1007/s42952-020-00077-2 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Ruler elements in chromatin remodelers set nucleosome array spacing and phasing​
    Oberbeckmann, E.; Niebauer, V.; Watanabe, S.; Farnung, L.; Moldt, M.; Schmid, A.& Cramer, P.  et al.​ (2020). DOI: https://doi.org/10.1101/2020.02.28.969618 
    ​Details  DOI 
  • 2020 | Preprint
    ​ ​Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology​
    Kargapolova, Y.; Rehimi, R.; Kayserili, H.; Brühl, J.; Zirkel, A.; Li, Y.& Yigit, G. et al.​ (2020). DOI: https://doi.org/10.1101/2020.01.27.921171 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​Fluorescence polarization filtering for accurate single molecule localization​
    Nevskyi, O.; Tsukanov, R. ; Gregor, I. ; Karedla, N.   & Enderlein, J. ​ (2020) 
    APL Photonics, 5(6) pp. 061302​.​ DOI: https://doi.org/10.1063/5.0009904 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper
    ​ ​The essential histogram​
    Li, H. ; Munk, A. ; Sieling, H.   & Walther, G.​ (2020) 
    Biometrika, 107(2) pp. 347​-364​.​ DOI: https://doi.org/10.1093/biomet/asz081 
    ​Details  DOI 
  • 2020 | Journal Article | Overview
    ​ ​Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells​
    Effertz, T. ; Moser, T.   & Oliver, D.​ (2020) 
    Faculty Reviews, 9 pp. 24​.​ DOI: https://doi.org/10.12703/r/9-24 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​NETT: solving inverse problems with deep neural networks​
    Li, H. ; Schwab, J.; Antholzer, S. & Haltmeier, M.​ (2020) 
    Inverse Problems, 36(6) pp. 065005​.​ DOI: https://doi.org/10.1088/1361-6420/ab6d57 
    ​Details  DOI 
  • 2020 | Preprint | 
    ​ ​Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software​
    Pein, F.; Eltzner, B.& Munk, A. ​ (2020)
    ​Details 
  • 2020 | Journal Article | Research Paper
    ​ ​Small-molecule inhibitors of human mitochondrial DNA transcription​
    Bonekamp, N. A.; Peter, B.; Hillen, H. S. ; Felser, A.; Bergbrede, T.; Choidas, A. & Horn, M. et al.​ (2020) 
    Nature, 588(7839) pp. 712-716​-716​.​ DOI: https://doi.org/10.1038/s41586-020-03048-z 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function​
    Dodonova, S. O; Zhu, F.; Dienemann, C.; Taipale, J. & Cramer, P. ​ (2020) 
    Nature, 580(7805) pp. 669​-672​.​ DOI: https://doi.org/10.1038/s41586-020-2195-y 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Doubling the resolution of a confocal spinning-disk microscope using image scanning microscopy​
    Qin, S.; Isbaner, S.; Gregor, I.   & Enderlein, J. ​ (2020) 
    Nature Protocols, 16(1) pp. 164​-181​.​ DOI: https://doi.org/10.1038/s41596-020-00408-x 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response​
    Stik, G.; Vidal, E.; Barrero, M.; Cuartero, S.; Vila-Casadesús, M.; Mendieta-Esteban, J. & Tian, T. V. et al.​ (2020) 
    Nature Genetics, 52(7) pp. 655​-661​.​ DOI: https://doi.org/10.1038/s41588-020-0643-0 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Emission States Variation of Single Graphene Quantum Dots​
    Ghosh, S.; Oleksiievets, N.; Enderlein, J.   & Chizhik, A. I. ​ (2020) 
    The Journal of Physical Chemistry Letters, 11(17) pp. 7356​-7362​.​ DOI: https://doi.org/10.1021/acs.jpclett.0c02008 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Generation of Engineered Human Myocardium in a Multi-well Format​
    Tiburcy, M. ; Meyer, T. ; Liaw, N. Y. & Zimmermann, W.-H. ​ (2020) 
    STAR Protocols, 1(1) art. 100032​.​ DOI: https://doi.org/10.1016/j.xpro.2020.100032 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations​
    Farnung, L.; Ochmann, M. & Cramer, P. ​ (2020) 
    eLife, 9.​ DOI: https://doi.org/10.7554/eLife.56178 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding​
    Wang, H.; Farnung, L.; Dienemann, C. & Cramer, P. ​ (2020) 
    Nature Structural & Molecular Biology, 27(1) pp. 8​-13​.​ DOI: https://doi.org/10.1038/s41594-019-0345-4 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Structure of replicating SARS-CoV-2 polymerase​
    Hillen, H. S. ; Kokic, G.; Farnung, L.; Dienemann, C.; Tegunov, D. & Cramer, P. ​ (2020) 
    Nature, 584(7819) pp. 154-156​-156​.​ DOI: https://doi.org/10.1038/s41586-020-2368-8 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Overview
    ​ ​Rosalind Franklin and the Advent of Molecular Biology​
    Cramer, P. ​ (2020) 
    Cell, 182(4) pp. 787​-789​.​ DOI: https://doi.org/10.1016/j.cell.2020.07.028 
    ​Details  DOI  PMID  PMC 
  • 2020 | Book Chapter
    ​ ​Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture​
    Chizhik, A. I.; Chizhik, A. M.; Ruhlandt, D.; Pfaff, J.; Karedla, N.; Gregor, I.& Kehlenbach, R. H.  et al.​ (2020)
    In:​Hancock, Ronald​ (Ed.), The Nucleus pp. 33​-45. (3. ed.). ​New York: ​Springer. DOI: https://doi.org/10.1007/978-1-0716-0763-3_4 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Overview
    ​ ​Structural Biology of RNA Polymerase II Transcription: 20 Years On​
    Osman, S. & Cramer, P. ​ (2020) 
    Annual Review of Cell and Developmental Biology, 36(1) pp. 1​-34​.​ DOI: https://doi.org/10.1146/annurev-cellbio-042020-021954 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes​
    Hillen, H. S. ; Bartuli, J.; Grimm, C.; Dienemann, C. ; Bedenk, K.; Szalay, A. A & Fischer, U. et al.​ (2019) 
    Cell, 179(7) pp. 1525​-1536​.​ DOI: https://doi.org/10.1016/j.cell.2019.11.023 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Sharing Data from Molecular Simulations​
    Abraham, M.; Apostolov, R.; Barnoud, J.; Bauer, P.; Blau, C. ; Bonvin, A. M. J. J. & Chavent, M. et al.​ (2019) 
    Journal of Chemical Information and Modeling, 59(10) pp. 4093-4099​-4099​.​ DOI: https://doi.org/10.1021/acs.jcim.9b00665 
    ​Details  DOI  PMID  PMC 
  • 2019 | Preprint
    ​ ​Multiscale quantile segmentation​
    Vanegas, L. J.; Behr, M.& Munk, A. ​ (2019)
    ​Details  arXiv 
  • 2019 | Preprint
    ​ ​Modeling Fluorescence Correlation Spectroscopy through an aberrating sphere​
    Ruhlandt, D.; Katti, A.; Derouard, J.; Delon, A.& Enderlein, J. ​ (2019)
    ​Details  arXiv 
  • 2019 | Preprint
    ​ ​Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome​
    Wagner, F. R.; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.& Cramer, P. ​ (2019). DOI: https://doi.org/10.1101/800508 
    ​Details  DOI 
  • 2019 | Journal Article | Overview
    ​ ​Organization and regulation of gene transcription​
    Cramer, P. ​ (2019) 
    Nature, 573(7772) pp. 45​-54​.​ DOI: https://doi.org/10.1038/s41586-019-1517-4 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Overview
    ​ ​Eukaryotic Transcription Turns 50​
    Cramer, P. ​ (2019) 
    Cell, 179(4) pp. 808​-812​.​ DOI: https://doi.org/10.1016/j.cell.2019.09.018 
    ​Details  DOI  PMID  PMC 
  • 2018 | Preprint
    ​ ​Posterior analysis of $ in the binomial $(n,p)$ problem with both parameters unknown -- with applications to quantitative nanoscopy​
    Schmidt-Hieber, J.; Schneider, L. F.; Staudt, T.; Krajina, A.; Aspelmeier, T.& Munk, A. ​ (2018)
    ​Details  arXiv 
  • 2018 | Preprint
    ​ ​Frame-constrained Total Variation Regularization for White Noise Regression​
    del Álamo, M.; Li, H.  & Munk, A. ​ (2018)
    ​Details  arXiv 
  • 2017 | Preprint
    ​ ​Minimax estimation in linear models with unknown finite alphabet design​
    Behr, M.  & Munk, A. ​ (2017)
    ​Details  arXiv 
  • 2016 | Preprint
    ​ ​The Essential Histogram​
    Li, H. ; Munk, A. ; Sieling, H.  & Walther, G.​ (2016)
    ​Details  arXiv 

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