Prof. Dr. Mathias Bähr

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Main Affiliation

Universitätsmedizin Göttingen

Staff Status

unigoe

Publications
Editorial
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2009 | Journal Article
Recombinant Human Erythropoietin in the Treatment of Acute Ischemic Stroke
Ehrenreich, H. ; Weißenborn, K.; Prange, H. ; Schneider, D.; Weimar, C.; Wartenberg, K. & Schellinger, P. D. et al. (2009)
Stroke, 40(12) pp. e647-e656. DOI: https://doi.org/10.1161/STROKEAHA.109.564872
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2009 | Journal Article |
Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy.
Weishaupt, J. H.; Dietz, G.; Göricke, B.; Bähr, M. ; Frank, T.; Schlachetzki, J. C. M. & Meuer, K. et al. (2009)
BMC Neuroscience,(10).
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2009 | Journal Article |
Role of N-Type Voltage-Dependent Calcium Channels in Autoimmune Optic Neuritis
Gadjanski, I.; Boretius, S.; Williams, S. K.; Lingor, P.; Knöferle, J.; Sättler, M. B. & Fairless, R. et al. (2009)
Annals of Neurology, 66 pp. 81-93. DOI: https://doi.org/10.1002/ ana.21668
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2009 | Journal Article | Research Paper
Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins
Nagel, F.; Bähr, M. & Dietz, G. P. H. (2009)
Brain Research Bulletin, 79(5) pp. 303-309. DOI: https://doi.org/10.1016/j.brainresbull.2009.04.010 10.1016/j.brainresbull.2009.04.010
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2009 | Journal Article | Research Paper
Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells
Bermel, C. ; Tönges, L. ; Planchamp, V. ; Gillardon, F.; Weishaupt, J. H. ; Dietz, G. P. H. & Bähr, M. et al. (2009)
Molecular and Cellular Neuroscience, 42(4) pp. 427-437. DOI: https://doi.org/10.1016/j.mcn.2009.09.005
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2009 | Journal Article | Research Paper
Proinflammatory cell stress in sporadic inclusion body myositis muscle: overexpression of alpha B-crystallin is associated with amyloid precursor protein and accumulation of beta-amyloid
Muth, I. E.; Barthel, K.; Bähr, M. ; Dalakas, M. C. & Schmidt, J. (2009)
Journal of Neurology, Neurosurgery & Psychiatry, 80(12) pp. 1344-1349. DOI: https://doi.org/10.1136/jnnp.2009.174276
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2009 | Journal Article | Research Paper
Bilateral ophthalmoplegia due to symmetric cavernous sinus metastasis from gastric adenocarcinoma
Ebert, S.; Pilgram, S. M.; Bähr, M. & Kermer, P. (2009)
Journal of the Neurological Sciences, 279(1-2) pp. 106-108. DOI: https://doi.org/10.1016/j.jns.2009.01.006
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2009 | Journal Article
TAT-Bcl-X-L improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia
Doeppner, T. R. ; Dietz, G. P. H. ; El Aanbouri, M.; Gerber, J.; Witte, O. W.; Bähr, M. & Weise, J. (2009)
Neurobiology of Disease, 34(1) pp. 87-94. DOI: https://doi.org/10.1016/j.nbd.2008.12.013
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2009 | Journal Article | Research Paper
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice
Doeppner, T. R. ; Nagel, F.; Dietz, G. P. H. ; Weise, J.; Tönges, L. ; Schwarting, S. & Bähr, M. (2009)
Journal of Cerebral Blood Flow & Metabolism, 29(6) pp. 1187-1196. DOI: https://doi.org/10.1038/jcbfm.2009.44
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2009 | Journal Article | Research Paper
BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution
Sroka, K. ; Voigt, A. ; Deeg, S. ; Reed, J. C.; Schulz, J. B. ; Bähr, M. & Kermer, P. (2009)
Journal of Neurochemistry, 111(3) pp. 801-807. DOI: https://doi.org/10.1111/j.1471-4159.2009.06363.x
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2008 | Journal Article | Research Paper
Automated cerebrospinal fluid cytology
Heller, T.; Nagel, I.; Ehrlich, B.; Bähr, M. & Strik, H. (2008)
Analytical and quantitative cytology and histology, 30(3) pp. 139-144.
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2008 | Journal Article
MRI of optic neuritis in a rat model
Boretius, S. ; Gadjanski, I. ; Demmer, I. ; Bähr, M. ; Diem, R. ; Michaelis, T. & Frahm, J. (2008)
NeuroImage, 41(2) pp. 323-334. DOI: https://doi.org/10.1016/j.neuroimage.2008.02.021
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2008 | Journal Article
Quantitative evaluation of chaperone activity and neuroprotection by different preparations of a cell-penetrating Hsp70
Nagel, F.; Dohm, C. P. ; Bähr, M. ; Wouters, F. S. & Dietz, G. P. (2008)
Journal of Neuroscience Methods, 171(2) pp. 226-232. DOI: https://doi.org/10.1016/j.jneumeth.2008.03.008
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2008 | Journal Article | Research Paper
Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia
Weise, J.; Doeppner, T. R. ; Müller, T.; Wrede, A.; Schulz-Schaeffer, W. J. ; Zerr, I. & Witte, O. W. et al. (2008)
Restorative neurology and neuroscience, 26(1) pp. 57-64.
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2008 | Journal Article |
The upregulation of GLAST-1 is an indirect antiapoptotic mechanism of GDNF and neurturin in the adult CNS
Koeberle, P. D. & Bähr, M. (2008)
Cell Death and Differentiation, 15(3) pp. 471-483. DOI: https://doi.org/10.1038/sj.cdd.4402281
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2008 | Journal Article | Research Paper
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice
Rohde, G.; Kermer, P. ; Reed, J. C.; Bähr, M. & Weishaupt, J. H. (2008)
Neuroscience, 157(4) pp. 844-849. DOI: https://doi.org/10.1016/j.neuroscience.2008.09.055
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2008 | Journal Article | Research Paper
BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity
Planchamp, V. ; Bermel, C. ; Tönges, L. ; Ostendorf, T.; Kügler, S. ; Reed, J. C. & Kermer, P. et al. (2008)
Brain, 131 pp. 2606-2619. DOI: https://doi.org/10.1093/brain/awn196
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2008 | Journal Article | Research Paper
Glial cell line-derived neurotrophic growth factor increases motility and survival of cultured mesenchymal stem cells and ameliorates acute kidney injury
Shi, H.; Patschan, D. ; Dietz, G. P. H. ; Bähr, M. ; Plotkin, M. & Goligorsky, M. S. (2008)
AJP: Renal Physiology, 294(1) pp. F229-F235. DOI: https://doi.org/10.1152/ajprenal.00386.2007
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2008 | Journal Article | Research Paper
Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis
Hein (née Maier), K.; Köhler, A.; Diem, R. ; Sättler, M. B. ; Demmer, I. ; Lange, P. & Bähr, M. et al. (2008)
Neuroscience Letters, 436(1) pp. 72-76. DOI: https://doi.org/10.1016/j.neulet.2008.02.064
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2008 | Journal Article | Research Paper
Membrane-permeable Bcl-x(L) prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra
Dietz, G. P. H. ; Stockhausen (née Peters), K. V.; Dietz, B. ; Falkenburger, B. H.; Valbuena, P. ; Opazo, F. & Lingor, P. et al. (2008)
Journal of Neurochemistry, 104(3) pp. 757-765. DOI: https://doi.org/10.1111/j.1471-4159.2007.05028.x
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2008 | Journal Article | Research Paper |
Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle
Schmidt, J. ; Barthel, K.; Wrede, A.; Salajegheh, M.; Bähr, M. & Dalakas, M. C. (2008)
Brain, 131(5) pp. 1228-1240. DOI: https://doi.org/10.1093/brain/awn053
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2008 | Journal Article | Research Paper
Slow breathing reduces sympathoexcitation in COPD
Raupach, T. ; Bähr, M. ; Herrmann, P. ; Luethje, L. ; Heusser, X.; Hasenfuß, G. & Bernardi, L. et al. (2008)
European Respiratory Journal, 32(2) pp. 387-392. DOI: https://doi.org/10.1183/09031936.00109607
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2008 | Journal Article | Research Paper |
Mutant SOD1 detoxification mechanisms in intact single cells
Ganesan, S.; Rohde, G.; Eckermann, K.; Sroka, K. ; Schaefer, M. K. E.; Dohm, C. P. & Kermer, P. et al. (2008)
Cell Death and Differentiation, 15(2) pp. 312-321. DOI: https://doi.org/10.1038/sj.cdd.4402262
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2008 | Journal Article | Research Paper
Flupirtine as Neuroprotective Add-On Therapy in Autoimmune Optic Neuritis
Sättler, M. B. ; Williams, S. K.; Neusch, C.; Otto, M. ; Pehlke, J. R.; Bähr, M. & Diem, R. (2008)
The American Journal of Pathology, 173(5) pp. 1496-1507. DOI: https://doi.org/10.2353/ajpath.2008.080491
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2008 | Journal Article | Research Paper
Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis
Sättler, M. B. ; Togni, M.; Gadjanski, I. ; Sühs, K.-W.; Meyer, N.; Bähr, M. & Diem, R. (2008)
Journal of Neuroimmunology, 193(1-2) pp. 77-86. DOI: https://doi.org/10.1016/j.jneuroim.2007.10.021
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2008 | Journal Article | Research Paper
Subcellular distribution affects BAG1 function
Liman, J. ; Faida, L. ; Dohm, C. P. ; Reed, J. C.; Bähr, M. & Kermer, P. (2008)
Brain Research, 1198 pp. 21-26. DOI: https://doi.org/10.1016/j.brainres.2008.01.010
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2008 | Journal Article | Research Paper
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease
Nagel, F.; Falkenburger, B. H.; Tönges, L. ; Kowsky, S.; Pöppelmeyer, C.; Schulz, J. B. & Bähr, M. et al. (2008)
Journal of Neurochemistry, 105(3) pp. 853-864. DOI: https://doi.org/10.1111/j.1471-4159.2007.05204.x
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2008 | Journal Article
Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology
Diem, R. ; Demmer, I. ; Boretius, S. ; Merkler, D. ; Schmelting, B. ; Williams, S. K. & Sättler, M. B. et al. (2008)
Investigative Opthalmology & Visual Science, 49(8) pp. 3707-3714. DOI: https://doi.org/10.1167/iovs.08-1896
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2008 | Journal Article | Research Paper
Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury
Schwarting, S.; Litwak, S.; Hao, W.; Bähr, M. ; Weise, J. & Neumann, H. (2008)
Stroke, 39(10) pp. 2867-2875. DOI: https://doi.org/10.1161/STROKEAHA.108.513978
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2008 | Journal Article | Research Paper
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells
Lingor, P. ; Tönges, L. ; Pieper, N. ; Bermel, C. ; Barski, E. ; Planchamp, V. & Bähr, M. (2008)
Brain, 131(1) pp. 250-263. DOI: https://doi.org/10.1093/brain/awm284
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2008 | Journal Article | Research Paper |
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen
Loh, S. H. Y.; Francescut, L.; Lingor, P. ; Bähr, M. & Nicotera, P. (2008)
Cell Death and Differentiation, 15(2) pp. 283-298. DOI: https://doi.org/10.1038/sj.cdd.4402258
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2007 | Journal Article | Research Paper
Monitoring of acute generalized status epilepticus using multilocal diffusion MR imaging: Early prediction of regional neuronal damage
Engelhorn, T.; Hufnagel, A.; Weise, J.; Bähr, M. & Dörfler, A. (2007)
AJNR, American journal of neuroradiology, 28(2) pp. 321-327.
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2007 | Journal Article | Research Paper |
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
Meuer, K. ; Suppanz, I. E. ; Lingor, P. ; Planchamp, V. ; Göricke, B.; Fichtner, L. & Braus, G. H. et al. (2007)
Cell Death and Differentiation, 14(4) pp. 651-661. DOI: https://doi.org/10.1038/sj.cdd.4402087
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2007 | Journal Article | Research Paper
Alpha-synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton
Esposito, A.; Dohm, C. P. ; Kermer, P. ; Bähr, M. & Wouters, F. S. (2007)
Neurobiology of Disease, 26(3) pp. 521-531. DOI: https://doi.org/10.1016/j.nbd.2007.01.014
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2007 | Journal Article | Research Paper
A highly sensitive automated complex running wheel test to detect latent motor deficits in the mouse MPTP model of Parkinson's disease
Liebetanz, D. ; Baier, P. C.; Paulus, W. ; Meuer, K. ; Bähr, M. & Weishaupt, J. H. (2007)
Experimental Neurology, 205(1) pp. 207-213. DOI: https://doi.org/10.1016/j.expneurol.2007.01.030
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2007 | Journal Article
Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation
Maier, K. ; Merkler, D. ; Gerber, J.; Taheri, N.; Kuhnert, A. V.; Williams, S. K. & Neusch, C. et al. (2007)
Neurobiology of Disease, 25(3) pp. 514-525. DOI: https://doi.org/10.1016/j.nbd.2006.10.022
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2007 | Journal Article | Research Paper
Bcl-X-L protects cerebellar granule neurons against the late phase, but not against the early phase of glutamate-induced cell death
Dietz, G. P. H. ; Dietz, B. & Bähr, M. (2007)
Brain Research, 1164 pp. 136-141. DOI: https://doi.org/10.1016/j.brainres.2007.06.025
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2007 | Journal Article | Research Paper
Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation
Peroni, D.; Negro, A.; Bähr, M. & Dietz, G. P. H. (2007)
Neuroscience Letters, 421(2) pp. 110-114. DOI: https://doi.org/10.1016/j.neulet.2007.05.046
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2007 | Journal Article | Research Paper
Targeting neurological disease with RNAi
Lingor, P. & Bähr, M. (2007)
Molecular BioSystems, 3(11) pp. 773-780. DOI: https://doi.org/10.1039/b701169e
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2007 | Journal Article | Research Paper
Mitofusin 2 gene mutation (R94Q) causing severe early-onset axonal polyneuropathy (CMT2A)
Neusch, C.; Senderek, J.; Eggermann, T.; Elolff, E.; Bähr, M. & Schneider-Gold, C. (2007)
European Journal of Neurology, 14(5) pp. 575-577. DOI: https://doi.org/10.1111/j.1468-1331.2006.01688.x
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2007 | Journal Article | Research Paper
Unsupervised fluorescence lifetime imaging microscopy for high content and high throughput screening
Esposito, A.; Dohm, C. P. ; Bähr, M. & Wouters, F. S. (2007)
Molecular & Cellular Proteomics, 6(8) pp. 1446-1454. DOI: https://doi.org/10.1074/mcp.T700006-MCP200
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2007 | Journal Article | Research Paper
Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo
Lingor, P. ; Teusch, N.; Schwarz, K.; Mueller, R.; Mack, H.; Bähr, M. & Mueller, B. K. (2007)
Journal of Neurochemistry, 103(1) pp. 181-189. DOI: https://doi.org/10.1111/j.1471-4159.2007.04756.x
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2007 | Journal Article | Research Paper
Enhanced poly (ADP-Ribose) polymerase-1 activation contributes to recombinant tissue plasminogen activator-induced aggravation of ischemic brain injury in vivo
Crome, O.; Doeppner, T. R. ; Schwarting, S.; Müller, B.; Bähr, M. & Weise, J. (2007)
Journal of Neuroscience Research, 85(8) pp. 1734-1743. DOI: https://doi.org/10.1002/jnr.21305
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2007 | Journal Article | Research Paper
Galectin-1 expression in human glioma cells: Modulation by ionizing radiation and effects on tumor cell proliferation and migration
Strik, H. M. ; Schmidt, K.; Lingor, P. ; Tönges, L. ; Kugler, W.; Nitsche, M. & Rabinovich, G. A. et al. (2007)
Oncology Reports, 18(2) pp. 483-488. DOI: https://doi.org/10.3892/or.18.2.483
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2006 | Journal Article
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment
Weishaupt, J. H. ; Bartels, C. ; Pölking, E. ; Dietrich, J.; Rohde, G. ; Poeggeler, B. & Mertens, N. et al. (2006)
Journal of Pineal Research, 41(4) pp. 313-323. DOI: https://doi.org/10.1111/j.1600-079X.2006.00377.x
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2006 | Journal Article | Research Paper
Models of monocytic invasion into glioma cell aggregates
Strik, H. M. ; Hulper, P.; Erdlenbruch, B.; Meier, J.; Kowalewski, A.; Hemmerlein, B. & Gold, R. et al. (2006)
Anticancer research, 26(2A) pp. 865-871.
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2006 | Journal Article | Research Paper
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis
Kaiser, M.; Maletzki, I.; Hülsmann, S. ; Holtmann, B.; Schulz-Schaeffer, W. ; Kirchhoff, F. & Bähr, M. et al. (2006)
Journal of Neurochemistry, 99(3) pp. 900-912. DOI: https://doi.org/10.1111/j.1471-4159.2006.04131.x
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2006 | Journal Article | Research Paper
PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms
Guegan, C.; Braudeau, J.; Couriaud, C.; Dietz, G. P. H. ; Lacombe, P.; Bähr, M. & Nosten-Bertrand, M. et al. (2006)
Neurobiology of Disease, 22(1) pp. 177-186. DOI: https://doi.org/10.1016/j.nbd.2005.10.014
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2006 | Journal Article | Research Paper
Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: A comparative study
Maier, K. ; Kuhnert, A. V.; Taheri, N.; Sättler, M. B. ; Storch, M. K.; Williams, S. K. & Bähr, M. et al. (2006)
The American Journal of Pathology, 169(4) pp. 1353-1364. DOI: https://doi.org/10.2353/ajpath.2006.060159
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2006 | Journal Article | Research Paper
Evaluation of epitope tags for protein detection after in vivo CNS gene transfer
Shevtsova, Z.; Malik, J. M. I.; Michel, U. ; Scholl, U.; Bähr, M. & Kugler, S. (2006)
European Journal of Neuroscience, 23(8) pp. 1961-1969. DOI: https://doi.org/10.1111/j.1460-9568.2006.04725.x
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2006 | Journal Article | Research Paper
Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: Discovery of a highly potent in vivo inhibitor and its action mechanism
Pietrancosta, N.; Moumen, A.; Dono, R.; Lingor, P. ; Planchamp, V. ; Lamballe, F. & Bähr, M. et al. (2006)
Journal of Medicinal Chemistry, 49(12) pp. 3645-3652. DOI: https://doi.org/10.1021/jm060318n
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2006 | Journal Article | Research Paper
Bcl-XL increases axonal numbers but not axonal elongation from rat retinal explants
Dietz, G. P. H. ; Dietz, B. & Bähr, M. (2006)
Brain Research Bulletin, 70(2) pp. 117-123. DOI: https://doi.org/10.1016/j.brainresbull.2006.03.022
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2006 | Journal Article | Research Paper
Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease
Dietz, G. P. H. ; Valbuena, P. C. ; Dietz, B. ; Meuer, K. ; Müller, P. ; Weishaupt, J. H. & Bähr, M. (2006)
Brain Research, 1082(1) pp. 61-66. DOI: https://doi.org/10.1016/j.brainres.2006.01.083
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2006 | Journal Article | Research Paper
Potentiation of in vivo neuroprotection by BclX(L) and GDNF co-expression depends on post-lesion time in deafferentiated CNS neurons
Shevtsova, Z.; Malik, I. ; Garrido, M.; Schoell, U.; Bähr, M. & Kügler, S. (2006)
Gene Therapy, 13(22) pp. 1569-1578. DOI: https://doi.org/10.1038/sj.gt.3302822
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2006 | Journal Article | Research Paper
Plasma exchange therapy for steroid-unresponsive multiple sclerosis relapses. Clinical experience with 16 patients
Schilling, S.; Linker, R. A. ; König, F. B. ; Koziolek, M. ; Bähr, M. ; Müller, G. A. & Paulus, W. et al. (2006)
Der Nervenarzt, 77(4) pp. 430-438. DOI: https://doi.org/10.1007/s00115-005-2019-1
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2006 | Journal Article | Research Paper
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury
Weise, J.; Sandau, R.; Schwarting, S.; Crome, O.; Wrede, A.; Schulz-Schaeffer, W. & Zerr, I. et al. (2006)
Stroke, 37(5) pp. 1296-1300. DOI: https://doi.org/10.1161/01.STR.0000217262.03192.d4
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2006 | Journal Article | Research Paper
Examination of cellular and molecular events associated with optic nerve Axotomy
Nitzan, A.; Kermer, P. ; Shirvan, A.; Bähr, M. ; Barzilai, A. & Solomon, A. S. (2006)
Glia, 54(6) pp. 545-556. DOI: https://doi.org/10.1002/glia.20398
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2006 | Journal Article | Research Paper
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: Impact on extracellular K+ regulation
Neusch, C.; Papadopoulos, N.; Müller, M. ; Maletzki, I.; Winter, S M; Hirrlinger, J. & Handschuh, M. et al. (2006)
Journal of Neurophysiology, 95(3) pp. 1843-1852. DOI: https://doi.org/10.1152/jn.00996.2005
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2006 | Journal Article | Research Paper
Comparison of test systems for RNAinterference
Malik, I. ; Garrido, M.; Bähr, M. ; Kügler, S. & Michel, U. (2006)
Biochemical and Biophysical Research Communications, 341(1) pp. 245-253. DOI: https://doi.org/10.1016/j.bbrc.2005.12.173
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2006 | Journal Article | Research Paper
TAT-BH4 and TAT-Bcl-x(L) peptides protect against sepsis-induced lymphocyte apoptosis in vivo
Hotchkiss, R. S.; Mcconnell, K. W.; Bullok, K.; Davis, C. G.; Chang, K. C.; Schwulst, S. J. & Dunne, J. C. et al. (2006)
The journal of immunology, 176(9) pp. 5471-5477. DOI: https://doi.org/10.4049/jimmunol.176.9.5471
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2006 | Journal Article | Research Paper
Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease
Meuer, K. ; Pitzer, C.; Teismann, P.; Krüger, C.; Göricke, B.; Laage, R. & Lingor, P. et al. (2006)
Journal of Neurochemistry, 97(3) pp. 675-686. DOI: https://doi.org/10.1111/j.1471-4159.2006.03727.x
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2006 | Journal Article | Research Paper
Bax inhibitor-1 protects neurons from oxygen-glucose deprivation
Dohm, C. P. ; Siedenberg, S. ; Liman, J. ; Esposito, A.; Wouters, F. S. ; Reed, J. C. & Bähr, M. et al. (2006)
Journal of Molecular Neuroscience, 29(1) pp. 1-8. DOI: https://doi.org/10.1385/JMN:29:1:1
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2006 | Journal Article | Research Paper
Transcranial color-coded duplex sonography in suspected acute basilar artery occlusion
Kermer, P. ; Wellmer, A. ; Crome, O.; Mohr, A. ; Knauth, M. & Bähr, M. (2006)
Ultrasound in Medicine & Biology, 32(3) pp. 315-320. DOI: https://doi.org/10.1016/j.ultrasmedbio.2005.12.004
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2006 | Journal Article | Letter Note
Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster
Ratzka, P. ; Schlachetzki, J. C. M.; Bähr, M. & Nau, R. (2006)
The Lancet, 367(9505). DOI: https://doi.org/10.1016/S0140-6736(06)67967-1
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2006 | Journal Article | Research Paper
Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons
Tönges, L. ; Lingor, P. ; Egle, R.; Dietz, G. P. H. ; Fahr, A. & Bähr, M. (2006)
RNA, 12(7) pp. 1431-1438. DOI: https://doi.org/10.1261/rna.2252206
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2006 | Journal Article | Research Paper
Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions
Sättler, M. B. ; Demmer, I. ; Williams, S. K.; Maier, K. ; Merkler, D. ; Gadjanski, I. & Stadelmann, C. et al. (2006)
Experimental Neurology, 201(1) pp. 172-181. DOI: https://doi.org/10.1016/j.expneurol.2006.04.015
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2006 | Journal Article | Research Paper
Improved high-capacity adenoviral vectors for high-level neuron-restricted gene transfer to the CNS
Hermening, S.; Kügler, S. ; Bähr, M. & Isenmann, S. (2006)
Journal of Virological Methods, 136(1-2) pp. 30-37. DOI: https://doi.org/10.1016/j.jviromet.2006.03.031
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2005 | Journal Article
Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis
Diem, R. ; Sättler, M. B. ; Merkler, D. ; Demmer, I. ; Maier, K. ; Stadelmann, C. & Ehrenreich, H. et al. (2005)
Brain, 128(2) pp. 375-385. DOI: https://doi.org/10.1093/brain/awh365
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2005 | Journal Article | Research Paper
Cerebral perfusion alterations during the acute phase of experimental generalized status epilepticus: Prediction of survival by using perfusion-weighted MR imaging and histopathology
Engelhorn, T.; Doerfler, A.; Weise, J.; Bähr, M. ; Forsting, M. & Hufnagel, A. (2005)
AJNR, American journal of neuroradiology, 26(6) pp. 1563-1570.
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2005 | Journal Article | Research Paper
Expression of the protein inhibitor of nitric oxide synthase in the adult rat retina before and after optic nerve lesion
Dietz, G. P. H. ; Schott, M.; Labes, M. & Bähr, M. (2005)
Molecular Brain Research, 136(1-2) pp. 118-124. DOI: https://doi.org/10.1016/j.molbrainres.2005.01.011
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2005 | Journal Article | Research Paper
Automated cerebrospinal fluid cytology - Limitations and reasonable applications
Strik, H. ; Luthe, H.; Nagel, I.; Ehrlich, B. & Bähr, M. (2005)
Analytical and quantitative cytology and histology, 27(3) pp. 167-173.
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2005 | Journal Article
Programmierter Zelltod in der Netzhaut: Molekulare Mechanismen und therapeutische Ansätze
Kermer, P. & Bähr, M. (2005)
Der Ophthalmologe, 102(7) pp. 674-678. DOI: https://doi.org/10.1007/s00347-005-1187-5
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2005 | Journal Article | Research Paper
Programmed cell death in the retina. Molecular mechanisms and therapeutic strategies
Kermer, P. & Bähr, M. (2005)
Der Ophthalmologe, 102(7) pp. 674-678.
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2005 | Journal Article | Research Paper
Mycophenolate mofetil: A new therapeutic option in neuroimmunological diseases
Schneider-Gold, C. ; Bähr, M. & Gold, R. (2005)
Aktuelle Neurologie, 32(8) pp. 477-480. DOI: https://doi.org/10.1055/s-2005-866941
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2005 | Journal Article | Research Paper
Simvastatin treatment does not protect retinal ganglion cells from degeneration in a rat model of autoimmune optic neuritis
Sattler, M.; Diem, R. ; Merkler, D. ; Demmer, I. ; Boger, I.; Stadelmann, C. & Bähr, M. (2005)
Experimental Neurology, 193(1) pp. 163-171. DOI: https://doi.org/10.1016/j.expneurol.2004.12.010
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2005 | Journal Article | Research Paper
Limited protection of TAT-Bcl-X-L against pneumolysin-induced neuronal cell death
Ebert, S.; Dietz, G. P. H. ; Mitchell, T. J.; Michel, U. ; Bähr, M. & Nau, R. (2005)
Neuroscience Letters, 384(3) pp. 349-353. DOI: https://doi.org/10.1016/j.neulet.2005.05.027
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2005 | Journal Article | Research Paper
Long-term in vivo inhibition of CNS neurodegeneration by Bcl-X-L gene transfer
Malik, J. M. I.; Shevtsova, Z.; Bähr, M. & Kugler, S. (2005)
Molecular Therapy, 11(3) pp. 373-381. DOI: https://doi.org/10.1016/j.ymthe.2004.11.014
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2005 | Journal Article | Research Paper
Tissue Plasminogen Activator-Induced Ischemic Injury Is Reversed by NMDA Antagonist MK-801 in vivo
Kilic, E. ; Kilic, U.; Bähr, M. & Hermann, D. M. (2005)
Neurodegenerative Diseases, 2(2) pp. 49-55. DOI: https://doi.org/10.1159/000089283
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2005 | Journal Article | Research Paper
HIV-tat-mediated BCl-X-L delivery protects retinal ganglion cells during experimental autoimmune optic neuritis
Diem, R. ; Taheri, N.; Dietz, G. P. H. ; Kuhnert, A. V.; Maier, K. ; Sattler, M. & Gadjanski, L. et al. (2005)
Neurobiology of Disease, 20(2) pp. 218-226. DOI: https://doi.org/10.1016/j.nbd.2005.03.003
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2005 | Journal Article | Research Paper
Expression time course and spatial after experimental neuronal cell death distribution of activated caspase-3 status epilepticus: Contribution of delayed to seizure-induced neuronal injury
Weise, J.; Engelhorn, T.; Dorfler, A.; Aker, S.; Bähr, M. & Hufnagel, A. (2005)
Neurobiology of Disease, 18(3) pp. 582-590. DOI: https://doi.org/10.1016/j.nbd.2004.10.025
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2005 | Journal Article | Research Paper
Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo
Lingor, P. ; Scholl, U.; Bähr, M. & Kugler, S. (2005)
Experimental Brain Research, 161(3) pp. 335-342. DOI: https://doi.org/10.1007/s00221-004-2077-9
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2005 | Journal Article | Research Paper
Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity
Liman, J. ; Ganesan, S.; Dohm, C. P. ; Krajewski, S.; Reed, J. C.; Bähr, M. & Wouters, F. S. et al. (2005)
Molecular and Cellular Biology, 25(9) pp. 3715-3725. DOI: https://doi.org/10.1128/MCB.25.9.3715-3725.2005
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2005 | Journal Article | Research Paper
Axotomy-induced early down-regulation of POU-IV class transcription factors Brn-3a and Brn-3b in retinal ganglion cells
Weishaupt, J. H. ; Klocker, N. & Bähr, M. (2005)
Journal of Molecular Neuroscience, 26(1) pp. 17-25. DOI: https://doi.org/10.1385/JMN:26:1:017
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2005 | Journal Article | Research Paper
Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons
Michel, U. ; Malik, I. ; Ebert, S.; Bähr, M. & Kugler, S. (2005)
Biochemical and Biophysical Research Communications, 326(2) pp. 307-312. DOI: https://doi.org/10.1016/j.bbrc.2004.11.029
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2005 | Journal Article | Research Paper
Peptide-enhanced cellular internalization of proteins in neuroscience
Dietz, G. P. H. & Bähr, M. (2005)
Brain Research Bulletin, 68(1-2) pp. 103-114. DOI: https://doi.org/10.1016/j.brainresbull.2005.08.015
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2005 | Journal Article | Research Paper |
NF-kappa B factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity
Pizzi, M.; Sarnico, I.; Boroni, F.; Benarese, M.; Steimberg, N.; Mazzoleni, G. & Dietz, G. P. H. et al. (2005)
Cell Death and Differentiation, 12(7) art. 1362. DOI: https://doi.org/10.1038/sj.cdd.4401598 10.1038/sj.cdd.4401742
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2005 | Journal Article | Letter Note
Pathophysiology of brain ischemia: Penumbra, gene expression, and future therapeutic options
Schaller, B. J.; Bähr, M. & Buchfelder, M. (2005)
European Neurology, 54(4) pp. 179-180. DOI: https://doi.org/10.1159/000090293
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2005 | Journal Article | Research Paper
Three-dimensional reconstruction and volumetry of intracranial haemorrhage and its mass effect
Strik, H. M. ; Borchert, H.; Fels, C.; Knauth, M. ; Rienhoff, O. ; Bähr, M. & Verhey, J. F. (2005)
Neuroradiology, 47(6) pp. 417-424. DOI: https://doi.org/10.1007/s00234-005-1373-9
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2005 | Journal Article | Research Paper
Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo
Lingor, P. ; Koeberle, P.; Kugler, S. & Bähr, M. (2005)
Brain, 128 pp. 550-558. DOI: https://doi.org/10.1093/brain/awh382
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2004 | Journal Article | Research Paper
Clinical Response Following Adjuvant Temozolomide in a Patient with Primary Cerebral Lymphoma
Strik, H. M. ; Spreer, A. ; Nagel, H. ; Jacob, S. ; Jung, W. ; Kitze, B. & Bähr, M. (2004)
Anticancer Research, 24(6) pp. 4121-4125.
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2004 | Journal Article |
Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis
Sättler, M. B. ; Merkler, D. ; Maier, K. ; Stadelmann, C. ; Ehrenreich, H. ; Bähr, M. & Diem, R. (2004)
Cell Death and Differentiation, 11(Suppl. 2) pp. S181-S192. DOI: https://doi.org/10.1038/sj.cdd.4401504
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2004 | Journal Article | Research Paper
Rifampicin attenuates brain damage in focal ischemia
Yulug, B.; Kilic, U.; Kilic, E. & Bähr, M. (2004)
Brain Research, 996(1) pp. 76-80. DOI: https://doi.org/10.1016/j.brainres.2003.10.012
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2004 | Journal Article | Research Paper
Increased protein expression from adenoviral shuttle plasmids and vectors by insertion of a small chimeric intron sequence
Hermening, S.; Kugler, S. ; Bähr, M. & Isenmann, S. (2004)
Journal of Virological Methods, 122(1) pp. 73-77. DOI: https://doi.org/10.1016/j.jviromet.2004.08.005
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2004 | Journal Article | Research Paper
Effect of Erythropoietin Axotomy-Induced Apoptosis in Rat Retinal Ganglion Cells
Weishaupt, J. H. ; Rohde, G. ; Pölking, E. ; Sirén, A.-L. ; Ehrenreich, H. & Bähr, M. (2004)
Investigative Ophthalmology & Visual Science, 45(5) pp. 1514-1522. DOI: https://doi.org/10.1167/iovs.03-1039
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2004 | Journal Article | Research Paper
The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice
Kilic, E. ; Weishaupt, J. H. ; Kilic, Ü.; Rohde, G. ; Yulug, B.; Peters, K. & Hermann, D. M. et al. (2004)
Neuroscience, 128(2) pp. 359-364. DOI: https://doi.org/10.1016/j.neuroscience.2004.06.064
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2004 | Journal Article | Research Paper
Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats
Maier, K. ; Rau, C. R.; Storch, M. K.; Sättler, M. B. ; Demmer, I. ; Weissert, R. & Taheri, N. et al. (2004)
Brain pathology, 14(4) pp. 378-387. DOI: https://doi.org/10.1111/j.1750-3639.2004.tb00081.x
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2004 | Journal Article | Research Paper
Upregulation of cellular prion protein (PrPc) after focal cerebral ischemia and influence of lesion severity
Weise, J.; Crome, O.; Sandau, R.; Schulz-Schaeffer, W. ; Baehr, M. & Zerr, I. (2004)
Neuroscience Letters, 372(1-2) pp. 146-150. DOI: https://doi.org/10.1016/j.neulet.2004.09.030
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2004 | Journal Article | Research Paper
Gender-specific risk of perioperative complications in carotid endarterectomy patients with contralateral carotid artery stenosis or occlusion
Weise, J.; Kuschke, S. & Bähr, M. (2004)
Journal of Neurology, 251(7) pp. 838-844. DOI: https://doi.org/10.1007/s00415-004-0438-8
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2004 | Journal Article | Research Paper
Mechanisms and time course of neuronal degeneration in experimental autoimmune encephalomyelitis
Hobom, M.; Storch, M. K.; Weisser, R.; Maier, K. ; Radhakrishnan, A.; Krämer, B. & Bähr, M. et al. (2004)
Brain pathology, 14(2) pp. 148-157. DOI: https://doi.org/10.1111/j.1750-3639.2004.tb00047.x
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2004 | Journal Article | Research Paper |
The TAT Protein Transduction Domain Enhances the Neuroprotective Effect of Glial-Cell-Line-Derived Neurotrophic Factor after Optic Nerve Transection
Kilic, U.; Kilic, E. ; Dietz, G. P. H. & Bähr, M. (2004)
Neurodegenerative Diseases, 1(1) pp. 44-49. DOI: https://doi.org/10.1159/000076669
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2004 | Journal Article | Research Paper
Excess Bcl-X-L increases the intrinsic growth potential of adult CNS neurons in vitro
Kretz, A.; Kugler, S. ; Happold, C.; Bähr, M. & Isenmann, S. (2004)
Molecular and Cellular Neuroscience, 26(1) pp. 63-74. DOI: https://doi.org/10.1016/j.mcn.2004.01.007
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2004 | Journal Article | Research Paper
Transfection of "naked" siRNA results in endosomal uptake and metabolic impairment in cultured neurons
Lingor, P. ; Michel, U. ; Scholl, U.; Bähr, M. & Kugler, S. (2004)
Biochemical and Biophysical Research Communications, 315(4) pp. 1126-1133. DOI: https://doi.org/10.1016/j.bbrc.2004.01.170
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2004 | Journal Article | Research Paper
Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro
Kilic, U.; Kilic, E. ; Lingor, P. ; Yulug, B. & Bähr, M. (2004)
Acta Neuropathologica, 108(1) pp. 65-68. DOI: https://doi.org/10.1007/s00401-004-0867-6
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2003 | Journal Article | Research Paper
Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway
Diem, R. ; Hobom, M.; Maier, K. ; Weissert, R.; Storch, M. K.; Meyer, R. & Bähr, M. (2003)
The Journal of neuroscience, 23(18) pp. 6993-7000.
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2003 | Journal Article | Research Paper
Differential transgene expression in brain cells in vivo and in vitro from AAV-2 vectors with small transcriptional control units
Kügler, S.; Schöll, U.; Zolotukhin, S.; Lingor, P. & Bähr, M. (2003)
Virology, 311(1) pp. 89-95. DOI: https://doi.org/10.1016/S0042-6822(03)00162-4
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2003 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
Editorial comment - Remote evaluation of acute ischemic stroke: A reliable tool to extend tissue plasminogen activator use to community and rural stroke patients?
Crome, O. & Bähr, M. (2003)
Stroke, 34(10) pp. E191-E192. DOI: https://doi.org/10.1161/01.STR.0000095163.28915.B9
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2003 | Journal Article | Research Paper
Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo
Weishaupt, J. H. ; Diem, R. ; Kermer, P. ; Krajewski, S.; Reed, J. C. & Bähr, M. (2003)
Neurobiology of Disease, 13(2) pp. 124-135. DOI: https://doi.org/10.1016/S0969-9961(03)00032-9
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2003 | Journal Article | Research Paper
Decreased amplitudes in multiple sclerosis patients with normal visual acuity: a VEP study
Diem, R. ; Tschirne, A. & Bähr, M. (2003)
Journal of Clinical Neuroscience, 10(1) pp. 67-70. DOI: https://doi.org/10.1016/S0967-5868(02)00172-8
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2003 | Journal Article | Research Paper
Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction
Weishaupt, J. H. ; Kussmaul, L.; Grotsch, P.; Hecke, A.; Rohde, G. ; Romig, H. & Bähr, M. et al. (2003)
Molecular and Cellular Neuroscience, 24(2) pp. 489-502. DOI: https://doi.org/10.1016/S1044-7431(03)00221-5
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2003 | Journal Article | Research Paper
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice
Kilic, U.; Kilic, E. ; Dietz, G. P. H. & Bähr, M. (2003)
Stroke, 34(5) pp. 1304-1310. DOI: https://doi.org/10.1161/01.STR.0000066869.45310.50
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2003 | Journal Article | Letter Note
Paraneoplastic polymyositis in recurring adrenal gland carcinoma
Lingor, P. ; von Boetticher, D. ; Bähr, M. & Fassbender, K. (2003)
The Lancet Neurology, 2(7) pp. 435-436. DOI: https://doi.org/10.1016/S1474-4422(03)00440-X
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2003 | Journal Article | Research Paper
Detection of acute thalamo-mesencephalic infarction: diffusion abnormality precedes T2 hyperintensity
Weise, J.; Bähr, M. ; Strayle-Batra, M. & Kuker, W. (2003)
Acta Neurologica Scandinavica, 108(1) pp. 52-54. DOI: https://doi.org/10.1034/j.1600-0404.2003.00094.x
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2003 | Journal Article | Research Paper
Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area
Kugler, S. ; Kilic, E. & Bähr, M. (2003)
Gene Therapy, 10(4) pp. 337-347. DOI: https://doi.org/10.1038/sj.gt.3301905
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2003 | Journal Article | Research Paper
Interleukin-1 beta protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo
Diem, R. ; Hobom, M.; Grotsch, P.; Krämer, B. & Bähr, M. (2003)
Molecular and Cellular Neuroscience, 22(4) pp. 487-500. DOI: https://doi.org/10.1016/S1044-7431(02)00042-8
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2002 | Journal Article
Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients
Jacob, S. ; Poeggeler, B. ; Weishaupt, J. H. ; Sirén, A.-L. ; Hardeland, R. ; Bähr, M. & Ehrenreich, H. (2002)
Journal of Pineal Research, 33(3) pp. 186-187. DOI: https://doi.org/10.1034/j.1600-079X.2002.02943.x
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2002 | Journal Article | Research Paper
Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice
Kilic, E. ; Hermann, D. M.; Isenmann, S. & Bähr, M. (2002)
Journal of Pineal Research, 32(2) pp. 106-111. DOI: https://doi.org/10.1034/j.1600-079x.2002.1823.x
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2002 | Journal Article | Research Paper
Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis
Straten, G.; Schmeer, C.; Kretz, A.; Gerhardt, E. ; Kugler, S. ; Schulz, J. B. & Gravel, C. et al. (2002)
Neurobiology of Disease, 11(1) pp. 123-133. DOI: https://doi.org/10.1006/nbdi.2002.0543
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2002 | Journal Article | Research Paper
Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice
Kilic, E. ; Dietz, G. P. H. ; Hermann, D. M. & Bähr, M. (2002)
Annals of Neurology, 52(5) pp. 617-622. DOI: https://doi.org/10.1002/ana.10356
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2002 | Journal Article | Research Paper
Inhibition of neuronal apoptosis in vitro and in vivo using TAT-Mediated protein transduction
Dietz, G. P. H. ; Kilic, E. & Bähr, M. (2002)
Molecular and Cellular Neuroscience, 21(1) pp. 29-37. DOI: https://doi.org/10.1006/mcne.2002.1165
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2002 | Journal Article | Research Paper
Adenovirus-mediated Bcl-X-L expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice
Kilic, E. ; Hermann, D. M.; Kugler, S. ; Kilic, U.; Holzmuller, H.; Schmeer, C. & Bähr, M. (2002)
Neurobiology of Disease, 11(2) pp. 275-284. DOI: https://doi.org/10.1006/nbdi.2002.0552
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2001 | Journal Article | Research Paper
Acute neuronal apoptosis in a rat model of multiple sclerosis
Meyer, R. ; Weissert, R.; Diem, R. ; Storch, M. K.; de Graaf, K. L.; Krämer, B. & Bähr, M. (2001)
The Journal of neuroscience, 21(16) pp. 6214-6220.
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2001 | Journal Article | Research Paper
Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand
Naumann, U.; Kugler, S. ; Wolburg, H.; Wick, W.; Rascher, G.; Schulz, J. B. & Conseiller, E. et al. (2001)
Cancer research, 61(15) pp. 5833-5842.
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2001 | Journal Article | Research Paper
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis
Roth, W.; Isenmann, S.; Nakamura, M.; Platten, M.; Wick, W.; Kleihues, P. & Bähr, M. et al. (2001)
Cancer research, 61(6) pp. 2759-2765.
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2001 | Journal Article | Letter Note
Molecular and cellular mechanisms of brain repair
Mueller, H. W. & Bahr, M. (2001)
Restorative Neurology and Neuroscience, 19(1-2).
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2001 | Journal Article | Research Paper
Degeneration of axotomized retinal ganglion cells as a model for neuronal apoptosis in the central nervous system - molecular death and survival pathways
Weishaupt, J. H. & Bähr, M. (2001)
Restorative neurology and neuroscience, 19(1-2) pp. 19-27.
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2001 | Journal Article | Research Paper
Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent Akt phosphorylation by tumor necrosis factor-alpha rescues axotomized retinal ganglion cells from retrograde cell death in vivo
Diem, R. ; Meyer, R. ; Weishaupt, J. H. & Bähr, M. (2001)
The Journal of neuroscience, 21(6) pp. 2058-2066.
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2001 | Journal Article | Research Paper |
Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection
Weise, J.; Isenmann, S. & Bähr, M. (2001)
Cell Death and Differentiation, 8(8) pp. 801-807. DOI: https://doi.org/10.1038/sj.cdd.4400872
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2001 | Journal Article | Research Paper
Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice
Hermann, D. M.; Kilic, E. ; Kugler, S. ; Isenmann, S. & Bähr, M. (2001)
Neurobiology of Disease, 8(4) pp. 655-666. DOI: https://doi.org/10.1006/nbdi.2001.0399
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2001 | Journal Article | Research Paper
Adenovirus-mediated glial cell line-derived neurotrophic factor (GDNF) expression protects against subsequent cortical cold injury in rats
Hermann, D. M.; Kilic, E. ; Kugler, S. ; Isenmann, S. & Bähr, M. (2001)
Neurobiology of Disease, 8(6) pp. 964-973. DOI: https://doi.org/10.1006/nbdi.2001.0448
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2001 | Journal Article | Research Paper
Transection of the optic nerve in rats: studying neuronal death and survival in vivo
Kermer, P. ; Klocker, N.; Weishaupt, J. H. & Bähr, M. (2001)
Brain Research Protocols, 7(3) pp. 255-260. DOI: https://doi.org/10.1016/S1385-299X(01)00076-9
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2001 | Journal Article | Research Paper
Cascade of caspase activation in potassium-deprived cerebellar granule neurons: Targets for treatment with peptide and protein inhibitors of apoptosis
Gerhardt, E. ; Kugler, S. ; Leist, M.; Beier, C.; Berliocchi, L.; Volbracht, C. & Weller, M. et al. (2001)
Molecular and Cellular Neuroscience, 17(4) pp. 717-731. DOI: https://doi.org/10.1006/mcne.2001.0962
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2001 | Journal Article | Research Paper
Intravitreal adenoviral gene transfer evokes an immune response in the retina that is directed against the heterologous lacZ transgene product but does not limit transgene expression
Isenmann, S.; Engel, S.; Kugler, S. ; Gravel, C.; Weller, M. & Bähr, M. (2001)
Brain Research, 892(2) pp. 229-240. DOI: https://doi.org/10.1016/S0006-8993(00)02957-7
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Neuron-specific expression of therapeutic proteins: Evaluation of different cellular promoters in recombinant adenoviral vectors
Kügler, S. ; Meyn, L.; Holzmüller, H.; Gerhardt, E. ; Isenmann, S.; Schulz, J. B. & Bähr, M. (2001)
Molecular and Cellular Neuroscience, 17(1) pp. 78-96. DOI: https://doi.org/10.1006/mcne.2000.0929
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Morphological and functional analysis of an incomplete CNS fiber tract lesion: Graded crush of the rat optic nerve
Klocker, N.; Zerfowski, M.; Gellrich, N. C. & Bähr, M. (2001)
Journal of Neuroscience Methods, 110(1-2) pp. 147-153. DOI: https://doi.org/10.1016/S0165-0270(01)00435-6
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
BDNF increases the number of axotomized rat retinal ganglion cells expressing GAP-43, L1, and TAG-1 mRNA - A supportive role for nitric oxide?
Klocker, N.; Jung, M.; Stuermer, C. A. O. & Bähr, M. (2001)
Neurobiology of Disease, 8(1) pp. 103-113. DOI: https://doi.org/10.1006/nbdi.2000.0329
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals
Coelln, R. von; Kugler, S. ; Weller, M.; Dichgans, J.; Bähr, M. & Schulz, J. B. (2001)
Journal of Neurochemistry, 77(1) pp. 263-273. DOI: https://doi.org/10.1046/j.1471-4159.2001.t01-1-00236.x
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve
Knoll, B.; Isenmann, S.; Kilic, E. ; Walkenhorst, J.; Engel, S.; Wehinger, J. & Bähr, M. et al. (2001)
Mechanisms of Development, 106(1-2) pp. 119-127. DOI: https://doi.org/10.1016/S0925-4773(01)00431-2
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice - Role of hemodynamic alterations
Kilic, E. ; Bähr, M. & Hermann, D. M. (2001)
Stroke, 32(11) pp. 2641-2647. DOI: https://doi.org/10.1161/hs1101.097381
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Modulation of metabotropic glutamate receptors fails to prevent the loss of adult rat retinal ganglion cells following axotomy or N-methyl-D-aspartate lesion in vivo
Kermer, P. ; Klocker, N. & Bähr, M. (2001)
Neuroscience Letters, 315(3) pp. 117-120. DOI: https://doi.org/10.1016/S0304-3940(01)02318-7
Details DOI PMID PMC WoS

2000 | Journal Article | Research Paper
Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3 '-kinase/protein kinase B signaling
Klocker, N.; Kermer, P. ; Weishaupt, J. H. ; Labes, M.; Ankerhold, R. & Bähr, M. (2000)
The Journal of neuroscience, 20(18) pp. 6962-6967.
Details PMID PMC WoS

2000 | Journal Article | Research Paper
Caspase-9: Involvement in secondary death of axotomized rat retinal ganglion cells in vivo
Kermer, P. ; Ankerhold, R.; Klocker, N.; Krajewski, S.; Reed, J. C. & Bähr, M. (2000)
Molecular Brain Research, 85(1-2) pp. 144-150. DOI: https://doi.org/10.1016/S0169-328X(00)00256-4
Details DOI WoS

2000 | Journal Article | Research Paper
Changes in BDNF and neurotrophin receptor expression in degenerating and regenerating rat retinal ganglion cells
Hirsch, S.; Labes, M. & Bähr, M. (2000)
Restorative neurology and neuroscience, 17(2-3) pp. 125-134.
Details PMID PMC WoS

2000 | Journal Article | Research Paper
Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent akt phosphorylation and inhibition of caspase-3 in vivo
Kermer, P. ; Klocker, N.; Labes, M. & Bähr, M. (2000)
The Journal of neuroscience, 20(2) pp. 722-728.
Details WoS

2000 | Journal Article | Research Paper
Adenovirus-mediated expression of ciliary neurotrophic factor (CNTF) rescues axotomized rat retinal ganglion cells but does not support axonal regeneration in vivo
Weise, J.; Isenmann, S.; Klocker, N.; Kugler, S. ; Hirsch, S.; Gravel, C. & Bähr, M. (2000)
Neurobiology of Disease, 7(3) pp. 212-223. DOI: https://doi.org/10.1006/nbdi.2000.0285
Details DOI PMID PMC WoS

2000 | Journal Article | Research Paper
Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
Eberhardt, O.; Coelln, R. V.; Kugler, S. ; Lindenau, J.; Rathke-Hartlieb, S.; Gerhardt, E. & Haid, S. et al. (2000)
The Journal of Neuroscience, 20(24) pp. 9126-9134. DOI: https://doi.org/10.1523/JNEUROSCI.20-24-09126.2000
Details DOI PMID PMC WoS

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